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Journal Articles

Bellio M, Garcia C, Edouard T, et al. Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions. Blood. 2019;134(25):2304-2317.

Blood (2020) 135 (24): 2197–2198.

https://doi.org/10.1182/blood.2020006308

Published: 2020

Journal Articles

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, Zhaojin Yu, Paulina Siejka-Zielinska, Zhenhua Chen, PhD, Emily Prince, Chao Shen, PhD, Zejuan Li, MD, Chunxiao Song, Yingming Zhao, Jianjun Chen, PhD

Blood (2019) 134 (Supplement_1): 1249.

https://doi.org/10.1182/blood-2019-127321

Published: 2019

Journal Articles

Loss of EZH2 Protein Expression in Myelodysplastic Syndrome Correlates with EZH2 Mutation and Portends a Worse Outcome

Ali Sakhdari, MD MSc, Caleb Class, PhD, Guillermo Montalban-Bravo, MD, Koji Sasaki, MD, Carlos E. Bueso-Ramos, MD PhD, Keyur P. Patel, MBBS, PhD, Joseph D. Khoury, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, L. Jeffrey Medeiros, MD, Rashmi Kanagal-Shamanna, MD

Blood (2019) 134 (Supplement_1): 3016.

https://doi.org/10.1182/blood-2019-131774

Published: 2019

Journal Articles

CCL2 Promotes Macrophages-Associated Chemoresistance Via MCPIP1 Dual Catalytic Activities in Multiple Myeloma

Ruyi Xu, Yi Li, MD, Haimeng Yan, MD, Xi Huang, MD, He Huang, MD PhD, Zhen Cai, MD PhD

Blood (2019) 134 (Supplement_1): 3086.

https://doi.org/10.1182/blood-2019-126498

Published: 2019

Journal Articles

Class I PI3K Is Required for HSC Differentiation

Kristina Ames, PhD, Imit Kaur, PhD, Meng Tong, Shayda Hemmati, PhD, Ellen Tein, Shira Glushakow-Smith, Lindsay Gurska, Kira Gritsman, MD PhD

Blood (2019) 134 (Supplement_1): 2461.

https://doi.org/10.1182/blood-2019-123823

Published: 2019

Journal Articles

Cofactor and Cofactor Mimetics

Peter J. Lenting, PhD

Blood (2019) 134 (Supplement_1): SCI-17.

https://doi.org/10.1182/blood-2019-121059

Published: 2019

Journal Articles

Heavy chain of FXII: not an innocent bystander!

Helen Philippou

Blood (2019) 133 (10): 1008–1009.

https://doi.org/10.1182/blood-2019-01-895110

Published: 2019

Journal Articles

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Nicolas Chatain, PhD, Juliane Lüscher-Firzlaff, Chao-Chung Kuo, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan Costa, Steffen Koschmieder, MD, Bernhard Lüscher

Blood (2018) 132 (Supplement 1): 2566.

https://doi.org/10.1182/blood-2018-99-115950

Published: 2018

Journal Articles

Elucidating the Non-Catalytic Function of Fatty Acid Synthase and Its Autophagy-Dependent Degradation in Acute Myelocytic Leukemia Differentiation Therapy

Magali Humbert, PhD, Severin Mosimann, Vreni Rentsch, Mario P. Tschan, PhD

Blood (2018) 132 (Supplement 1): 2624.

https://doi.org/10.1182/blood-2018-99-112068

Published: 2018

Journal Articles

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Meiling May, BA, Stephen Desiderio, MD PhD, John Thomas Bettridge, BA

Blood (2018) 132 (Supplement 1): 512.

https://doi.org/10.1182/blood-2018-99-116675

Published: 2018

Journal Articles

Contribution of Factor VIII A3 Domain Residues 1793-1795 to a Factor IXa-Interactive Site

Masahiro Takeyama, Keiji Nogami, MDPhD, Kana Sasai, Midori Shima, MD PhD

Blood (2018) 132 (Supplement 1): 1173.

https://doi.org/10.1182/blood-2018-99-113260

Published: 2018

Journal Articles

Kinetic Catalytic Inhibition and Cell-Based Analysis, Not Just Target Binding, Are Required to Assess Kinase Selectivity of Covalent Inhibitors: Comparable BTK vs TEC Selectivity Profile for Ibrutinib and Acalabrutinib

Melissa Hopper, MS, Tarikere Gururaja, PhD, Taisei Kinoshita, PhD, James P. Dean, Ronald Hill, PhD, Ann Mongan, PhD

Blood (2018) 132 (Supplement 1): 3498.

https://doi.org/10.1182/blood-2018-99-110849

Published: 2018

Journal Articles

Hematopoietic-Specific CSNK2B Loss in Mice Causes Impaired Erythropoiesis

Laura Quotti Tubi, PhD, Sara Canovas Nunes, PhD, Marilena Carrino, PhD, Ketty Gianesin, PhD, Sabrina Manni, PhD, Odile Filhol-Cochet, PhD, Brigitte Boldyreff, PhD, Livio Trentin, MD, Gianpietro Semenzato, MD, Francesco Piazza, MD

Blood (2017) 130 (Supplement 1): 82.

https://doi.org/10.1182/blood.V130.Suppl_1.82.82

Published: 2017

Journal Articles

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Alboukadel Kassambara, PhD, Laurie Herviou, Michel Jourdan, Coraline Thibaut, Veronika Vikova, Olivier Elemento, PhD, Jerome Moreaux, PhD

Blood (2017) 130 (Supplement 1): 4382.

https://doi.org/10.1182/blood.V130.Suppl_1.4382.4382

Published: 2017

Journal Articles

Non-Catalytic Role of SETD1A Regulates DNA Repair in Leukemia

Takayuki Hoshii, PhD, Paolo Cifani, PhD, Tomoyoshi Nakadai, PhD, Zhaohui Feng, BM, BS, Chun-Hao Huang, PhD, Richard Koche, PhD, Christopher D Delaney, Chun-Wei David Chen, PhD, Scott W. Lowe, PhD, Robert Roeder, PhD, Alex Kentsis, MD PhD, Scott A. Armstrong, MD PhD

Blood (2016) 128 (22): 434.

https://doi.org/10.1182/blood.V128.22.434.434

Published: 2016

Journal Articles

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

Tushar Murthy, MS, Theresa Bluemn, Manoj M. Pillai, MD, Alex C Minella, MD

Blood (2016) 128 (22): 1480.

https://doi.org/10.1182/blood.V128.22.1480.1480

Published: 2016

Journal Articles

New Hyperactive Factor IX Variants Bioengineered Based upon Biochemical Studies of Factor IX Padua

Ben J. Samelson-Jones, MD PhD, Jonathan D Finn, PhD, Rodney M. Camire, PhD, Valder R Arruda, MD PhD

Blood (2016) 128 (22): 1384.

https://doi.org/10.1182/blood.V128.22.1384.1384

Published: 2016

Journal Articles

The PAF Complex Regulation of Prmt5 Facilitates Leukemic Progression

Justin Serio, B.S., Wei Chen, Maria Mysliwski, Lili Chen, PhD, James Ropa, B.S., Jingya Wang, PhD, Andrew G. Muntean, PhD

Blood (2016) 128 (22): 3914.

https://doi.org/10.1182/blood.V128.22.3914.3914

Published: 2016

Journal Articles

Allosteric Regulation of V(D)J Recombination By Active Chromatin

John T Bettridge, Chan-Hyun Na, PhD, Akhilesh Pandey, MD PhD, Stephen Desiderio, MD PhD

Blood (2016) 128 (22): 3707.

https://doi.org/10.1182/blood.V128.22.3707.3707

Published: 2016

Journal Articles

Identification of a Factor X-Interactive Site on the Factor VIII A2 Domain

Masahiro Takeyama, MD PhD, Keiji Nogami, MD PhD, Shoko Furukawa, MD, Midori Shima, MD PhD

Blood (2016) 128 (22): 3760.

https://doi.org/10.1182/blood.V128.22.3760.3760

Published: 2016

NARROW

Bellio M, Garcia C, Edouard T, et al. Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions. Blood. 2019;134(25):2304-2317.

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Loss of EZH2 Protein Expression in Myelodysplastic Syndrome Correlates with EZH2 Mutation and Portends a Worse Outcome

CCL2 Promotes Macrophages-Associated Chemoresistance Via MCPIP1 Dual Catalytic Activities in Multiple Myeloma

Class I PI3K Is Required for HSC Differentiation

Cofactor and Cofactor Mimetics

Heavy chain of FXII: not an innocent bystander!

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Elucidating the Non-Catalytic Function of Fatty Acid Synthase and Its Autophagy-Dependent Degradation in Acute Myelocytic Leukemia Differentiation Therapy

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Contribution of Factor VIII A3 Domain Residues 1793-1795 to a Factor IXa-Interactive Site

Kinetic Catalytic Inhibition and Cell-Based Analysis, Not Just Target Binding, Are Required to Assess Kinase Selectivity of Covalent Inhibitors: Comparable BTK vs TEC Selectivity Profile for Ibrutinib and Acalabrutinib

Hematopoietic-Specific CSNK2B Loss in Mice Causes Impaired Erythropoiesis

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Non-Catalytic Role of SETD1A Regulates DNA Repair in Leukemia

SF3B1 Interactions with Chromatin Are Dynamic and Regulated in a Cell Cycle-Dependent Manner

New Hyperactive Factor IX Variants Bioengineered Based upon Biochemical Studies of Factor IX Padua

The PAF Complex Regulation of Prmt5 Facilitates Leukemic Progression

Allosteric Regulation of V(D)J Recombination By Active Chromatin

Identification of a Factor X-Interactive Site on the Factor VIII A2 Domain

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American Society of Hematology

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