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Journal Articles

High-Throughput Immunofluorescence and Electron Tomography to Characterize Centrosomal Aberrations in Plasma Cell Neoplasia

Tobias Dittrich, MD, Martin Schorb, Isabella Haberbosch, MD, Elena Bausch, PhD, Mandy Börmel, Marco Cosenza, PhD, Hartmut Goldschmidt, MD, Carsten Müller-Tidow, MD, Marc S Raab, MD PhD, Ute Hegenbart, MD, Stefan O. Schönland, MD, Yannick Schwab, PhD, Alwin Krämer, MD

Blood (2019) 134 (Supplement_1): 3077.

https://doi.org/10.1182/blood-2019-130713

Published: 2019

Journal Articles

A Semi-Automated Knime-Based Workflow for High Throughput Quantification and Analysis of Centrosome Aberrations

Tobias Dittrich, MD, Elena Bausch, PhD, Johannes Bausch, PhD, Hartmut Goldschmidt, MD, Ute Hegenbart, MD, Stefan O. Schönland, MD, Marc S Raab, MD PhD, Alwin Krämer, MD

Blood (2019) 134 (Supplement_1): 3379.

https://doi.org/10.1182/blood-2019-129863

Published: 2019

Journal Articles

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Adrian R. Wilkie, PhD, Leila J. Noetzli, PhD, Genevieve Couldwell, Anthony R. Sciaudone, Anjana Ray, PhD, Kellie R. Machlus, PhD, Joseph E. Italiano, Jr., BS, PhD

Blood (2019) 134 (Supplement_1): 721.

https://doi.org/10.1182/blood-2019-130803

Published: 2019

Journal Articles

VPS4A mutations Cause a Syndrome with Dyserythropoiesis, Hemolytic Anemia, and Neurodevelopmental Delay

Katie Giger Seu, PhD, Lisa Trump, PhD, Sana Emberesh, MBBS, Robert B. Lorsbach, MD PhD, Clarissa E. Johnson, MD, Jessica Meznarich, MD, Hunter Underhill, MD PhD, Haripriya Sakthivel, Omar Niss, MD, Shannon Nortman, Lionel Blanc, PhD, Wenying Zhang, MD PhD, Carolyn Lutzko, PhD, Theodosia A. Kalfa, MD PhD

Blood (2019) 134 (Supplement_1): 339.

https://doi.org/10.1182/blood-2019-128230

Published: 2019

Journal Articles

Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells

Ryo Uozaki, Shuji Aida, Takasi Yamagughi, Tomofumi Yamamoto, BPharm, Sho Kashiwazaki, Hiroshi Yanagawa, Daiju Ichikawa, Maiko Matsushita, Yutaka Hattori

Blood (2018) 132 (Supplement 1): 4451.

https://doi.org/10.1182/blood-2018-99-115909

Published: 2018

Journal Articles

Expression Signature of Myeloma Residual Cells Is Characterized By Genes Associated with Proliferation, Epigenetic Modification, and Stem Cell Maintenance

Michael A Bauer, PhD, Matthew Henry, M.S., Purvi Patel, Yan Wang, Joshua Epstein, DSc, Faith E. Davies, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Frits van Rhee, MD PhD, Gareth Morgan, MD, Brian A Walker, PhD, Sarah K Johnson, PhD

Blood (2018) 132 (Supplement 1): 4465.

https://doi.org/10.1182/blood-2018-99-119131

Published: 2018

Journal Articles

Genomic Landscape of Multiple Myeloma with Elevated Lactate Dehydrogenase

Susan Bal, MBBS, Saulius K. Girnius, MD, Daniel T. Starczynowski, PhD, Heather J. Landau, MD, Kwangmin Choi, PhD

Blood (2018) 132 (Supplement 1): 470.

https://doi.org/10.1182/blood-2018-99-115523

Published: 2018

Journal Articles

Targeting WEE1 Kinase after G2/M Checkpoint Arrest Induces Apoptosis in Chronic Myeloid Leukemia Progenitors

Manuela Mancini, PhD, Sara De Santis, Cecilia Monaldi, Fausto Castagnetti, MD PhD, Luana Bavaro, Margherita Martelli, Gabriele Gugliotta, MD PhD, Gianantonio Rosti, MD, Elena Tenti, PhD, Maria Alessandr Santucci, MD, Michele Cavo, MD, Giovanni Martinelli, MD, Simona Soverini, PhD

Blood (2017) 130 (Supplement 1): 1588.

https://doi.org/10.1182/blood.V130.Suppl_1.1588.1588

Published: 2017

Journal Articles

Possible Involvement of YB-1 in Abnormal Nuclear Shape of Adult T-Cell　Leukemia/Lymphoma Cell

Misaki Kakoki, Hiroo Katsuya, MD, Paola Miyazato, PhD, Takafumi Noguchi, Yuki Inada, Misaki Matsuo, Hiroyuki Hata, MDPhD, Tokio Tani, Yorifumi Satou, MD PhD

Blood (2017) 130 (Supplement 1): 5150.

https://doi.org/10.1182/blood.V130.Suppl_1.5150.5150

Published: 2017

Journal Articles

High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster

Felipe C Souza, Msc., Josiane L Schiavinato, PhD, Antonio R. Lucena-Araujo, PhD, Fabio M Oliveira, PhD, Amelia G Araújo, Dimas Tadeu Covas, MD, PhD, Carlos Martínez-A, PhD, Marco A Zago, MD PhD, Rodrigo A Panepucci, PhD

Blood (2016) 128 (22): 2029.

https://doi.org/10.1182/blood.V128.22.2029.2029

Published: 2016

Journal Articles

Cdkn3 Knockout Mice Develop Hematopoietic Malignancies

Zejin Sun, MD PhD, Donna Cerabona, Ying He, Grzegorz Nalepa, MD PhD

Blood (2016) 128 (22): 1537.

https://doi.org/10.1182/blood.V128.22.1537.1537

Published: 2016

Journal Articles

Concordant Underexpression of Fanconi Anemia/BRCA1 Pathway Proteins in a Major Proportion of Myelodysplastic Syndromes

Fatemeh Majidi, MD, Judith Neukirchen, MD, Ulrich Germing, M. D., Ron-Patrick Cadeddu, Stefan Braunstein, MD, Rainer Haas, MD, Norbert Gattermann, MD

Blood (2016) 128 (22): 4311.

https://doi.org/10.1182/blood.V128.22.4311.4311

Published: 2016

Journal Articles

Kinome-Wide shRNA Screen Reveals Functional Connections Between FANCA, Mitotic Centrosomes and the Spindle Assembly Checkpoint Tumor Suppressor Pathways

Richa Sharma, MD, Zahi Abdul Sater, Rikki Enzor, PhD, Ying He, Grzegorz Nalepa, MDPhD

Blood (2015) 126 (23): 3612.

https://doi.org/10.1182/blood.V126.23.3612.3612

Published: 2015

Journal Articles

A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium

Blood (2015) 126 (23): 3840.

https://doi.org/10.1182/blood.V126.23.3840.3840

Published: 2015

Journal Articles

Impaired Spindle Assembly Checkpoint In Vivo Promotes MDS/AML in a Novel Mouse Model of Fanconi Anemia

Donna Cerabona, Zahi Abdul Sater, Elizabeth Sierra Potchanant, PhD, Ying He, Zejin Sun, MD PhD, Grzegorz Nalepa, MDPhD

Blood (2015) 126 (23): 1211.

https://doi.org/10.1182/blood.V126.23.1211.1211

Published: 2015

Journal Articles

A Striking Reduction of Monoclonal Protein in a Patient with Concurrent Plasma Cell Dyscrasia and CMML-2, after Treatment with Rigosertib (01910.Na)

Jamile M. Shammo, MD, Agne Paner, MD, MV Ramana Reddy, PhD, Rachel L Mitchell, MD, Parameswaran Venugopal, MD

Blood (2015) 126 (23): 5362.

https://doi.org/10.1182/blood.V126.23.5362.5362

Published: 2015

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

Upfront 28-Day Metronomic Therapy for High-Risk Multiple Myeloma (HRMM)

Sharmilan Thanendrarajan, MD, Daisy V. Alapat, MD, Maurizio Zangari, MD, Carolina Schinke, MD, Christoph Heuck, MD, Frits van Rhee, MD PhD, Adam Rosenthal, Joshua Epstein, DSc, Shmuel Yaccoby, PhD, Faith E Davies, MD, Gareth J Morgan, MDPhD, Bart Barlogie, MD PhD

Blood (2015) 126 (23): 1843.

https://doi.org/10.1182/blood.V126.23.1843.1843

Published: 2015

Journal Articles

Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice

Marianna Trakala, David Partida, María Salazar-Roa, María Maroto, Paulina Wachowicz, Guillermo de Cárcer, Marcos Malumbres

Blood (2015) 126 (14): 1707–1714.

https://doi.org/10.1182/blood-2015-03-634402

Published: 2015

Includes: Supplemental data

Journal Articles

Morgana acts as an oncosuppressor in chronic myeloid leukemia

Blood (2015) 125 (14): 2245–2253.

https://doi.org/10.1182/blood-2014-05-575001

Published: 2015

Includes: Supplemental data

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High-Throughput Immunofluorescence and Electron Tomography to Characterize Centrosomal Aberrations in Plasma Cell Neoplasia

A Semi-Automated Knime-Based Workflow for High Throughput Quantification and Analysis of Centrosome Aberrations

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

VPS4A mutations Cause a Syndrome with Dyserythropoiesis, Hemolytic Anemia, and Neurodevelopmental Delay

Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells

Expression Signature of Myeloma Residual Cells Is Characterized By Genes Associated with Proliferation, Epigenetic Modification, and Stem Cell Maintenance

Genomic Landscape of Multiple Myeloma with Elevated Lactate Dehydrogenase

Targeting WEE1 Kinase after G2/M Checkpoint Arrest Induces Apoptosis in Chronic Myeloid Leukemia Progenitors

Possible Involvement of YB-1 in Abnormal Nuclear Shape of Adult T-Cell　Leukemia/Lymphoma Cell

High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster

Cdkn3 Knockout Mice Develop Hematopoietic Malignancies

Concordant Underexpression of Fanconi Anemia/BRCA1 Pathway Proteins in a Major Proportion of Myelodysplastic Syndromes

Kinome-Wide shRNA Screen Reveals Functional Connections Between FANCA, Mitotic Centrosomes and the Spindle Assembly Checkpoint Tumor Suppressor Pathways

A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium

Impaired Spindle Assembly Checkpoint In Vivo Promotes MDS/AML in a Novel Mouse Model of Fanconi Anemia

A Striking Reduction of Monoclonal Protein in a Patient with Concurrent Plasma Cell Dyscrasia and CMML-2, after Treatment with Rigosertib (01910.Na)

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Upfront 28-Day Metronomic Therapy for High-Risk Multiple Myeloma (HRMM)

Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice

Morgana acts as an oncosuppressor in chronic myeloid leukemia

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