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Journal Articles

A FULLY Human Bispecific Antibody Functionally Rescues Factor VIII Deficiency EX VIVO

Wei Wang, PhD, John Blackwood, PhD, Roberto Magliozzi, PhD, Leonardo Moraes, PhD, Jeffrey Hollins, PhD, Alessandro Sinopoli, PhD, Bertie Chi, PhD, Laura Mitchell, PhD, Chris Sellick, PhD, Claire Pearce, PhD, Igor Theurl, MD PhD, Volker Germaschewski, Jacob Galson, PhD, Luca Badiali, PhD, Karen Dickson, PhD, Allan Bradley, PhD, E-Chiang Lee, PhD

Blood (2019) 134 (Supplement_1): 2410.

https://doi.org/10.1182/blood-2019-123359

Published: 2019

Journal Articles

Functional Properties of Hb S and Hb C in Stored Cpda-1 Red Blood Cells Concentrate — a Prospective Study

Susan Elisabeth Jorge, MMSc, PhD, Marcela Regina Grigoleto, BSc, Maria Lourdes Barjas Castro, MD PhD, Fernando F. Costa, MD, PhD, Maria de Fátima Sonati, MSc, PhD

Blood (2018) 132 (Supplement 1): 2548.

https://doi.org/10.1182/blood-2018-99-117298

Published: 2018

Journal Articles

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Valerie Anne Novakovic, MS, Gary E Gilbert, MD

Blood (2017) 130 (Supplement 1): 1064.

https://doi.org/10.1182/blood.V130.Suppl_1.1064.1064

Published: 2017

Journal Articles

Phe174-Mutated Human Factor X As Bypassing Agent to the Direct FXa Inhibitors

Mark Schreuder, MD, Daniel Verhoef, MSc, Ka Lei Cheung, Koen Visscher, MSc, Daan Geerke, PhD, Pieter H. Reitsma, PhD, Mettine H.A. Bos, PhD

Blood (2017) 130 (Supplement 1): 363.

https://doi.org/10.1182/blood.V130.Suppl_1.363.363

Published: 2017

Journal Articles

Preclinical Development of Gene Therapy for X-Linked Severe Combined Immunodeficiency (SCID-X1)

Valentina Poletti, PhD, Sabine Charrier, PhD, Samia Martin, Bernard Gjata, Alban Vignaud, PhD, Fang Zhang, PhD, Karen Buckland, PhD, Michael Rothe, PhD, Axel Schambach, MD PhD, Sung-Yun Pai, MD, David A. Williams, MD, H. Bobby Gaspar, MD PhD, Adrian J Thrasher, MD PhD, Fulvio Mavilio, PhD

Blood (2016) 128 (22): 4705.

https://doi.org/10.1182/blood.V128.22.4705.4705

Published: 2016

Journal Articles

Therapeutic Activity of Peg Albumin in Transgenic Mouse Model of Sickle Cell Disease Is a Function of the Pattern of Pegylation

Devendra Lingojwar, PhD, Savita Bhutoria, PhD, Fantao Meng, PhD, Sangeetha Thangaswamy, PhD, Henny H Billett, MD, Caterina Minniti, MD, Amy Tsai, PhD, Marcos Intaglietta, PhD, Craig A Branch, PhD, Seetharama A Acharya, PhD

Blood (2016) 128 (22): 4848.

https://doi.org/10.1182/blood.V128.22.4848.4848

Published: 2016

Journal Articles

Novel Human Factor VIII Variant with Impaired Intracellular Processing Exhibits Enhanced In Vivo Efficacy

Giang N. Nguyen, B.S., Christian M. Wood, Tanner Dirstine, B.S., Robert J. Davidson, B.S., Denise E. Sabatino, PhD

Blood (2016) 128 (22): 256.

https://doi.org/10.1182/blood.V128.22.256.256

Published: 2016

Journal Articles

Pre-Targeted Radioimmunotherapy Employing a Recombinant Bispecific Antibody Using a Murine Xenograft Model of Human Leukemia

Aimee L. Kenoyer, BS, Yukang Lin, PhD, Johnnie J. Orozco, MD PhD, Ethan Balkin, Don Hamlin, BS, Alexandra H. Hernandez, BS, Chen Fang, PhD, Kelly Laird, Sofia H.L. Frost, PhD, Mark Hylarides, PhD, Kelly D. Orcutt, PhD, D Scott Wilbur, PhD, K. Dane Wittrup, PhD, Oliver W. Press, MD PhD, John Pagel, MD PhD

Blood (2014) 124 (21): 3749.

https://doi.org/10.1182/blood.V124.21.3749.3749

Published: 2014

Journal Articles

Human Factor VIII Variants with Diminished PACE-Furin Cleavage Exhibit Increased Biological Activity and Therapeutic Efficacy

Giang N. Nguyen, Joshua I. Siner, Robert J. Davidson, Valder R. Arruda, MD PhD, Rodney M. Camire, PhD, Denise E. Sabatino, PhD

Blood (2014) 124 (21): 104.

https://doi.org/10.1182/blood.V124.21.104.104

Published: 2014

Journal Articles

Reduced Antigenicity of Recombinant Ovine Factor VIII in Hemophilia A Inhibitor Patient Plasmas

Philip M Zakas, Shannon L. Meeks, MD, Christopher B Doering, PhD

Blood (2012) 120 (21): 1124.

https://doi.org/10.1182/blood.V120.21.1124.1124

Published: 2012

Journal Articles

Generation of a Novel Bispecific Antibody (ACE910) Against Activated Factor IX and Factor X Mimicking the Function of Factor VIII Cofactor Activity

Tomoyuki Igawa, PhD, Zenjiro Sampei, Tetsuhiro Soeda, PhD, Yukiko Okuyama-Nishida, PhD, Chifumi Moriyama, Tetsuya Wakabayashi, Eriko Tanaka, Atsushi Muto, Tetsuo Kojima, PhD, Takehisa Kitazawa, DVM, Kazutaka Yoshihashi, DVM, PhD, Aya Harada, Miho Funaki, Kenta Haraya, Tachibana Tatsuhiko, PhD, Sachiyo Suzuki, Keiko Esaki, Yoshiaki Nabuchi, PhD, Kunihiro Hattori, PhD

Blood (2012) 120 (21): 1126.

https://doi.org/10.1182/blood.V120.21.1126.1126

Published: 2012

Journal Articles

High Margin of Pathogen Safety for a Plasma-Derived FXIII Concentrate for the Treatment of Congenital FXIII Deficiency

Albrecht Groener, Thomas Nowak, Birgit Popp, Wolfram Schäfer

Blood (2011) 118 (21): 4655.

https://doi.org/10.1182/blood.V118.21.4655.4655

Published: 2011

Journal Articles

Expression of the Light Chain of Coagulation Factor VIII in Insect Cells

Svetlana A Shestopal, PhD, James H Kurasawa, MS, Timothy K Lee, PhD, Andrey G Sarafanov, PhD

Blood (2011) 118 (21): 2269.

https://doi.org/10.1182/blood.V118.21.2269.2269

Published: 2011

Journal Articles

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

Valerie A Novakovic, M.S., Hongzhi Miao, Steven Pipe, MD, Gary E. Gilbert, M.D.

Blood (2011) 118 (21): 2243.

https://doi.org/10.1182/blood.V118.21.2243.2243

Published: 2011

Journal Articles

Does Protease Domain of Human Factor IXa Contain a Sodium Site? Evidence From the 1.64 Å Resolution Crystal Structure

Kanagasabai Vadivel, Amy E Schmidt, S. Paul Bajaj

Blood (2011) 118 (21): 2246.

https://doi.org/10.1182/blood.V118.21.2246.2246

Published: 2011

Journal Articles

Development and Characterization of Recombinant Ovine Factor VIII

Philip M Zakas, Bagirath Gangadharan, MS, Graca Almeida-Porada, MD, PhD, Christopher D Porada, PhD, H. Trent Spencer, PhD, Christopher B Doering, PhD

Blood (2011) 118 (21): 1193.

https://doi.org/10.1182/blood.V118.21.1193.1193

Published: 2011

Journal Articles

GRP-78 Secreted by Tumor Cells Blocks the Anti-Angiogenic Activity of Bortezomib.

Johann Kern, Gerold Untergasser, PhD, Christoph Zenzmaier, Bettina Sarg, Gunther Gastl, Prof., Dr., Eberhard Gunsilius, M.D., Michael Steurer, MD

Blood (2009) 114 (22): 4805.

https://doi.org/10.1182/blood.V114.22.4805.4805

Published: 2009

Journal Articles

Comparative Decay Rates of Human, Rhesus Macaque, Cynomolgus, and Porcine Activated Factor VIII.

John F Healey, BS, Ernest Parker, BS, John (Pete) S. Lollar, MD

Blood (2009) 114 (22): 3164.

https://doi.org/10.1182/blood.V114.22.3164.3164

Published: 2009

Journal Articles

Effect of Membrane Binding Upon Intramolecular Dynamics of the Factor VIII C2 Domain.

Dennis Pantazatos, PhD, Christopher Gessner, Virgil Woods, MD, Gary E. Gilbert, MD

Blood (2009) 114 (22): 3168.

https://doi.org/10.1182/blood.V114.22.3168.3168

Published: 2009

Journal Articles

Decreased Immunogenicity of Purified Topical Bovine Thrombin Preparations.

He Zhu, MD, Debra Hoppensteadt, Rakesh Wahi, MD, Jawed Fareed

Blood (2009) 114 (22): 4209.

https://doi.org/10.1182/blood.V114.22.4209.4209

Published: 2009

NARROW

A FULLY Human Bispecific Antibody Functionally Rescues Factor VIII Deficiency EX VIVO

Functional Properties of Hb S and Hb C in Stored Cpda-1 Red Blood Cells Concentrate — a Prospective Study

Factor VIII Binds to an Acidic Fibrinogen Variant, a Critical Component of the High-Affinity Fibrin Binding Site, Resulting in Increased Cofactor Activity

Phe174-Mutated Human Factor X As Bypassing Agent to the Direct FXa Inhibitors

Preclinical Development of Gene Therapy for X-Linked Severe Combined Immunodeficiency (SCID-X1)

Therapeutic Activity of Peg Albumin in Transgenic Mouse Model of Sickle Cell Disease Is a Function of the Pattern of Pegylation

Novel Human Factor VIII Variant with Impaired Intracellular Processing Exhibits Enhanced In Vivo Efficacy

Pre-Targeted Radioimmunotherapy Employing a Recombinant Bispecific Antibody Using a Murine Xenograft Model of Human Leukemia

Human Factor VIII Variants with Diminished PACE-Furin Cleavage Exhibit Increased Biological Activity and Therapeutic Efficacy

Reduced Antigenicity of Recombinant Ovine Factor VIII in Hemophilia A Inhibitor Patient Plasmas

Generation of a Novel Bispecific Antibody (ACE910) Against Activated Factor IX and Factor X Mimicking the Function of Factor VIII Cofactor Activity

High Margin of Pathogen Safety for a Plasma-Derived FXIII Concentrate for the Treatment of Congenital FXIII Deficiency

Expression of the Light Chain of Coagulation Factor VIII in Insect Cells

Conservative Mutations in the Membrane-Binding Motif of Factor V C2 Domain to Residues of Pseudonaja Textilis Venom Factor V Confer Phosphatidylserine-Independent Activity

Does Protease Domain of Human Factor IXa Contain a Sodium Site? Evidence From the 1.64 Å Resolution Crystal Structure

Development and Characterization of Recombinant Ovine Factor VIII

GRP-78 Secreted by Tumor Cells Blocks the Anti-Angiogenic Activity of Bortezomib.

Comparative Decay Rates of Human, Rhesus Macaque, Cynomolgus, and Porcine Activated Factor VIII.

Effect of Membrane Binding Upon Intramolecular Dynamics of the Factor VIII C2 Domain.

Decreased Immunogenicity of Purified Topical Bovine Thrombin Preparations.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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