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Journal Articles

Unveiling a Critical Role of Thrombin in Enhanced CD8+ T Cell Response to Cancer

Rachel Cantrell, BS, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Balkrishan Sharma, PhD, Alexey Revenko, PhD, Brett P Monia, PhD, Joseph S. Palumbo, MD

Blood (2019) 134 (Supplement_1): 4918.

https://doi.org/10.1182/blood-2019-128739

Published: 2019

Journal Articles

Recombinant Human Thrombopoietin Increases Platelet Numbers and Reduces the Risk of Bleeding Events in Thrombocytopenic Patients with Chronic Hepatitis B Virus Infection: A Multicenter Observational Study

Blood (2018) 132 (Supplement 1): 4990.

https://doi.org/10.1182/blood-2018-99-116000

Published: 2018

Journal Articles

Prolonged Prothrombin Time in DIC: Contributions of Excess Thrombin and Fibrinogen Degradation Products

Michael Meledeo, PhD, Prajeeda M Nair, PhD, Grantham Peltier, MS, Ashley S Taylor, BA, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2017) 130 (Supplement 1): 2346.

https://doi.org/10.1182/blood.V130.Suppl_1.2346.2346

Published: 2017

Journal Articles

Prothrombin "Carmel": Identification of a Novel Homozygous Mutation in the Prothrombin Gene Causing Coagulation Factor II Deficiency and Inherited Bleeding Disorder in an Israeli Arab Family

Emad Muhammad, PhD, Aliza Cassel, PhD, Miriam Berl, Meir Preis, MD PhD, Ayala Rozano Gorelick, MD

Blood (2017) 130 (Supplement 1): 4872.

https://doi.org/10.1182/blood.V130.Suppl_1.4872.4872

Published: 2017

Journal Articles

Idarucizumab for Reversing Anticoagulation in Patients Treated with Dabigatran: Experience in Our Center

Estefania Morente Constatin, MDCINE Resident, Marta Rivas Luque, Pablo Romero Garcia, MDCINE Resident, Maria Almudena Garcia-Ruiz, Manuel Jurado, MD PhD

Blood (2017) 130 (Supplement 1): 4923.

https://doi.org/10.1182/blood.V130.Suppl_1.4923.4923

Published: 2017

Journal Articles

Three Factor Prothrombin Complex Concentrates in Cardiac Surgery: A Novel Algorithmic Approach to Perioperative Bleeding

Nazish Khalid Hashmi, MD, Kamrouz Ghadimi, Jacob Schroder, Jerrold Levy, MD, Ian J Welsby, MD

Blood (2016) 128 (22): 5035.

https://doi.org/10.1182/blood.V128.22.5035.5035

Published: 2016

Journal Articles

Restoration of Procoagulant Factor Levels after Cardiac Surgery Causes Thrombin Generation to Rise to Thrombotic Levels

Romy Kremers, MSc, Yvonne Bosch, MSc, Saartje Bloemen, PhD, Bas De Laat, MD PhD, Rob Wagenvoord, PhD, Raed Al Dieri, PhDPharmD, Coenraad Hemker, MD PhD

Blood (2015) 126 (23): 1143.

https://doi.org/10.1182/blood.V126.23.1143.1143

Published: 2015

Journal Articles

Characterization of a High-Affinity Fully Human IgG2 Antibody Against Tissue Factor Pathway Inhibitor As a Bypass Agent for the Treatment of Hemophilia

Maxine Bauzon, Bing Liu, Joanna Grudzinska-Goebel, Jan Tebbe, Junliang Pan, Jill Cifrese, Zhuozhi Wang, Derek Sim

Blood (2015) 126 (23): 3513.

https://doi.org/10.1182/blood.V126.23.3513.3513

Published: 2015

Journal Articles

Thrombin and Factor XII Drive Prostate Tumor Growth In Vivo

Gregory Adams, PhD, Leah Rosenfeldt, BS, Malinda Frederick, BS, Keith Kombrinck, MS, Brett P. Monia, PhD, Alexey Revenko, PhD, Joseph S. Palumbo, MD

Blood (2015) 126 (23): 424.

https://doi.org/10.1182/blood.V126.23.424.424

Published: 2015

Journal Articles

Thrombin Drives Colorectal Cancer Pathogenesis at the Level of Primary Tumor Growth, Tumor Invasion and Metastasis

Gregory N Adams, PhD, Dusty Waltz, Leah Rosenfeldt, Malinda Frederick, Whitney Miller, Alexey S Revenko, PhD, Brett P. Monia, PhD, Joseph S. Palumbo, MD

Blood (2014) 124 (21): 2812.

https://doi.org/10.1182/blood.V124.21.2812.2812

Published: 2014

Journal Articles

Diminished Multi-Organ Pathologies and Inflammation Associated With Sickle Cell Disease In Mice With Genetically Limited Prothrombin Levels

Paritha Arumugam, PhD, Eric S. Mullins, MD, Maureen A Shaw, MS, Kumar Shanmukhappa, BVSc., PhD, Anastacia Loberg, Tilat Rizvi, PhD, Janaka Wansapura, PhD, David Witte, MD, Punam Malik, MD, Jay L. Degen, PhD

Blood (2013) 122 (21): 729.

https://doi.org/10.1182/blood.V122.21.729.729

Published: 2013

Journal Articles

Thrombin Inhibition Prevents Against Severe Atherosclerosis Progression in Prothrombotic Mice

Henri M.H. Spronk, PhD, Julian I Borissoff, Oliver Soehnlein, Rory Koenen, Rene van Oerle, Sylvia Heeneman, Mat J.A.P. Daemen, Charles T Esmon, PhD, Jay L. Degen, PhD, Hartmut Weiler, PhD, Joanne van Ryn, MSc, PhD, Hugo Ten Cate, MD, PhD

Blood (2012) 120 (21): 103.

https://doi.org/10.1182/blood.V120.21.103.103

Published: 2012

Journal Articles

Thrombin Supports Colitis and Colitis-Associated Cancer Pathogenesis

Brian K. Turpin, DO, Whitney M Miller, Eric S. Mullins, MD, Jay L. Degen, PhD, Matthew J. Flick, PhD, Brett P. Monia, PhD, Robert MacLeod, Ph.D., Alexey S Revenko, PhD, Joseph S. Palumbo, MD

Blood (2011) 118 (21): 2237.

https://doi.org/10.1182/blood.V118.21.2237.2237

Published: 2011

Journal Articles

Determination of the International Sensitivity Index for Rivaroxaban Using the WHO RBT/90 Thromboplastin as a Calibrant for Other Thromboplastin Reagents.

Job Harenberg, Prof., Dr., Christina Giese, Svetlana Marx, Dipl., Math., Roland Kraemer, Prof., Dr.

Blood (2010) 116 (21): 1089.

https://doi.org/10.1182/blood.V116.21.1089.1089

Published: 2010

Journal Articles

Thrombin-Thrombomodulin Interactions Are An Important Determinant of Metastatic Potential

Netanel A Horowitz, MD, Elizabeth A. Blevins, Whitney M Miller, Ashely R Perry, Kathryn E Talmage, Eric S. Mullins, MD, Brett P. Monia, PhD, Jay L. Degen, PhD, Joseph S. Palumbo, MD

Blood (2010) 116 (21): 822.

https://doi.org/10.1182/blood.V116.21.822.822

Published: 2010

Journal Articles

EspP, An Extracellular Serine Protease From Enterohemorrhagic E. Coli , Induces Coagulopathy In Human Whole Blood and Plasma

Kevin H.M. Kuo, MD, Shekeb Khan, MSc, Elena Brnjac, MLT, Emil F. Pai, Dr.rer.nat, Alden E. Chesney, MD

Blood (2010) 116 (21): 4416.

https://doi.org/10.1182/blood.V116.21.4416.4416

Published: 2010

Journal Articles

Predicting Thrombosis in Factor V Leiden Heterozygotes.

Stephen J. Everse, Ph.D., Thomas Orfeo, Ph.D., Kathleen E. Brummel-Ziedins, Ph.D., Matthew F. Hockin, Ph.D., Kenneth G. Mann, Ph.D.

Blood (2008) 112 (11): 1818.

https://doi.org/10.1182/blood.V112.11.1818.1818

Published: 2008

Journal Articles

Prothrombin 20209C>T: Thirteen New Cases and Association with the 19911A>G Polymorphism.

Ilka Warshawsky, MD, PhD, Vinit Makkar, MD, Kandice Kottke-Marchant, MD, PhD

Blood (2008) 112 (11): 1827.

https://doi.org/10.1182/blood.V112.11.1827.1827

Published: 2008

Journal Articles

The G20210A Mutation Alters the Structure and Function of Prothrombin mRNA.

J. Eric Russell, MD, Xingge Liu, MD

Blood (2006) 108 (11): 1610.

https://doi.org/10.1182/blood.V108.11.1610.1610

Published: 2006

Journal Articles

Conditional Disruption of the Murine Prothrombin Gene.

Eric S. Mullins, MD, Matthew J. Flick, PhD, Keith W. Kombrinck, Sandra J. Degen, PhD, William Sun, PhD, Jay L. Degen, PhD

Blood (2006) 108 (11): 1600.

https://doi.org/10.1182/blood.V108.11.1600.1600

Published: 2006

NARROW

Unveiling a Critical Role of Thrombin in Enhanced CD8+ T Cell Response to Cancer

Recombinant Human Thrombopoietin Increases Platelet Numbers and Reduces the Risk of Bleeding Events in Thrombocytopenic Patients with Chronic Hepatitis B Virus Infection: A Multicenter Observational Study

Prolonged Prothrombin Time in DIC: Contributions of Excess Thrombin and Fibrinogen Degradation Products

Prothrombin "Carmel": Identification of a Novel Homozygous Mutation in the Prothrombin Gene Causing Coagulation Factor II Deficiency and Inherited Bleeding Disorder in an Israeli Arab Family

Idarucizumab for Reversing Anticoagulation in Patients Treated with Dabigatran: Experience in Our Center

Three Factor Prothrombin Complex Concentrates in Cardiac Surgery: A Novel Algorithmic Approach to Perioperative Bleeding

Restoration of Procoagulant Factor Levels after Cardiac Surgery Causes Thrombin Generation to Rise to Thrombotic Levels

Characterization of a High-Affinity Fully Human IgG2 Antibody Against Tissue Factor Pathway Inhibitor As a Bypass Agent for the Treatment of Hemophilia

Thrombin and Factor XII Drive Prostate Tumor Growth In Vivo

Thrombin Drives Colorectal Cancer Pathogenesis at the Level of Primary Tumor Growth, Tumor Invasion and Metastasis

Diminished Multi-Organ Pathologies and Inflammation Associated With Sickle Cell Disease In Mice With Genetically Limited Prothrombin Levels

Thrombin Inhibition Prevents Against Severe Atherosclerosis Progression in Prothrombotic Mice

Thrombin Supports Colitis and Colitis-Associated Cancer Pathogenesis

Determination of the International Sensitivity Index for Rivaroxaban Using the WHO RBT/90 Thromboplastin as a Calibrant for Other Thromboplastin Reagents.

Thrombin-Thrombomodulin Interactions Are An Important Determinant of Metastatic Potential

EspP, An Extracellular Serine Protease From Enterohemorrhagic E. Coli , Induces Coagulopathy In Human Whole Blood and Plasma

Predicting Thrombosis in Factor V Leiden Heterozygotes.

Prothrombin 20209C>T: Thirteen New Cases and Association with the 19911A>G Polymorphism.

The G20210A Mutation Alters the Structure and Function of Prothrombin mRNA.

Conditional Disruption of the Murine Prothrombin Gene.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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