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Journal Articles

Simultaneous bone marrow involvement by CLL/SLL and LEF1/cyclin D1-positive metastatic melanoma

Kirill A. Lyapichev, Fatima Z. Jelloul
Journal: Blood
Blood (2020) 136 (2): 258.
https://doi.org/10.1182/blood.2020006057
Published: 2020
Journal Articles

Notch1 mutation in B Chronic Lymphocytic Lymphocytes Induces Proliferation through Cell Cycle G1/S Phase-Specific Cyclin Overexpression

Ana M Hurtado López, Tzu Hua Chen-Liang, María Zurdo, Anna Puiggros, PhD, Andrea Gómez-Llonín, B.Sc., María-Dolores García-Malo, MD, Francisco José Ortuño, Vicente Vicente Garcia, MD PhD, Blanca Espinet, PhD, Andres Jerez
Journal: Blood
Blood (2019) 134 (Supplement_1): 851.
https://doi.org/10.1182/blood-2019-127960
Published: 2019
Journal Articles

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Ting Du, PhD, Yan Song, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3074.
https://doi.org/10.1182/blood-2019-130236
Published: 2019
Journal Articles

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Kathleen E. McGrath, PhD, Catherman C Seana, MS, Zachary T Hilt, MS, Katherine H Fegan, MS, Paul D. Kingsley, PhD, Leah A Vitt, BS, Massiel Chavez Stolla, PhD, Craig N. Morrell, PhD, James Palis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2470.
https://doi.org/10.1182/blood-2019-131039
Published: 2019
Journal Articles

Graft-Versus-Host Disease Causes the Failure of Donor Hematopoietic Progenitor Cells to Reconstitute Plasmacytoid Dendritic Cells That Promote Tolerance of Donor T Cells Against the Host

Yuanyuan Tian, Lijun Meng, PhD, Hongshuang Yu, Ying Wang, PhD, Tien Bui, Shin Mineishi, MD, Hong Zheng, MD PhD, Stefania Gallucci, MD, Yanyun Zhang, Shaoyan Hu, MD PhD, Yi Zhang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 193.
https://doi.org/10.1182/blood-2019-128721
Published: 2019
Journal Articles

Akt Inhibition Differently Controls PRC2 Components and Synergizes with Dual EZH2/1 Inhibitor in the Treatment of Multiple Myeloma

Mohamed Rizk, BSc, MSc, Ola Rizq, MD PhD, Motohiko Oshima, PhD, Yaeko Nakajima-Takagi, PhD, Shuhei Koide, PhD, Atsunori Saraya, Yusuke Isshiki, MD PhD, Tetsuhiro Chiba, MD PhD, Satoshi Yamazaki, PhD, Anqi Ma, PhD, Jian Jin, PhD, Atsushi Iwama, MD PhD, Naoya Mimura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4400.
https://doi.org/10.1182/blood-2019-122157
Published: 2019
Journal Articles

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Taylor J Chen, BS, Ye Shen, PhD, Cory Seth Bridges, BS, Chun Shik Park, PhD, Jacob J. Junco, PhD, Karen R. Rabin, MD PhD, H. Daniel Lacorazza, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3889.
https://doi.org/10.1182/blood-2019-129127
Published: 2019
Journal Articles

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Takashi Ishio, Joji Shimono, Sarvesh Kumar, Yuquan Lin, Emmanuel Bachy, Michael N. Petrus, Yandan Yang, Michiyuki Maeda, Hideki Goto, Satoshi Hashino, Takanori Teshima, MD, Thomas A. Waldmann, MD, Louis Staudt, MD, Masao Nakagawa
Journal: Blood
Blood (2019) 134 (Supplement_1): 3781.
https://doi.org/10.1182/blood-2019-124670
Published: 2019
Journal Articles

P53 Pathway Activation Mediated High c-MAF Expression Is Associated with Overall and Post-Progression Survival in Multiple Myeloma

Eiko Yamane, Master, Graduate Student, Tsukasa Oda, PhD, Masanobu Sunaga, Master, Graduate Student, Yuki Murakami, Master, Graduate Student, Rei Ishihara, Master, Graduate Student, Yuta Asao, Graduate Student, Yuta Masuda, Master, Saki Watanabe, Master, Nobuhiko Kobayashi, MD PhD, Hisashi Takei, MD, Yohei Osaki, MD PhD, Gotoh Nanami, Tetsuhiro Kasamatsu, PhD, Hiroaki Shimizu, MD PhD, Takuma Ishizaki, MD PhD, Hiromi Koiso, MD PhD, Makiko Takizawa, MD PhD, Yoshiyuki Ogawa, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MD PhD, Takayuki Saitoh, MD PhD, Hirokazu Murakami, MD PhD, Hiroshi Handa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4330.
https://doi.org/10.1182/blood-2019-125172
Published: 2019
Journal Articles

T Cell Immunity Toward Viral- and Tumor-Antigens Is Preserved in MDS Patients

Hussein Hamad, MD, Wingchi K Leung, MD, Spyridoula Vasileiou, PhD, Shivani Mukhi, Quillan Huang, MD, George Carrum, MD, Carlos A. Ramos, MD, Rammurti Kamble, MD, LaQuisa C. Hill, MD, Ann M. Leen, PhD, Premal Lulla, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4225.
https://doi.org/10.1182/blood-2019-126792
Published: 2019
Journal Articles

CDK6 Antagonizes TP53-Induced Responses during Tumorigenesis

Veronika Sexl, MD PhD, Karoline Kollmann, PhD, Florian Bellutti
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-15.
https://doi.org/10.1182/blood-2019-121101
Published: 2019
Journal Articles

Mcph1 , Mutated in Primary Microcephaly, Is Required to Complete Terminal Erythroid Differentiation

Yoann Vial, PharmD, Jeannette Nardelli, PhD, Justine Rousselot, Emilie Lepeu, Michele Souyri, PhD, Sandrine Passemard, MD PhD, Helene Cave, PharmD, PhD, Severine Drunat, PharmD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1192.
https://doi.org/10.1182/blood-2019-126475
Published: 2019
Journal Articles

Panobinostat (LBH589) in Combination with the β-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both in Vitro and In Vivo

Ioanna Savvidou, MD, Tiffany Khong, BSc, PhD, Sophie Whish, Tara Sepehrizadeh, Sridurga Mithraprabhu, PhD MSc, Michael DeVeer, BSc, PhD, Andrew Spencer, DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 5540.
https://doi.org/10.1182/blood-2019-126468
Published: 2019
Journal Articles

Overexpression of Mir-21-5p Induces Apoptosis and Cell Cycle Arrest By Down-Regulating SKP2 and Overcomes Bortezomib Resistance in Multiple Myeloma

Jonahunnatha Nesson George William, PhD, Jian Wu, MD, Ziyan Chen, Omar Faruq, PhD, Hong Chang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1823.
https://doi.org/10.1182/blood-2019-128917
Published: 2019
Journal Articles

CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1 − mantle cell lymphoma

David Martín-Garcia, Alba Navarro, Rafael Valdés-Mas, Guillem Clot, Jesús Gutiérrez-Abril, Miriam Prieto, Inmaculada Ribera-Cortada, Renata Woroniecka, Grzegorz Rymkiewicz, Susanne Bens, Laurence de Leval, Andreas Rosenwald, Judith A. Ferry, Eric D. Hsi, Kai Fu, Jan Delabie, Dennis Weisenburger, Daphne de Jong, Fina Climent, Sheila J. O’Connor, Steven H. Swerdlow, David Torrents, Sergi Beltran, Blanca Espinet, Blanca González-Farré, Luis Veloza, Dolors Costa, Estella Matutes, Reiner Siebert, German Ott, Leticia Quintanilla-Martinez, Elaine S. Jaffe, Carlos López-Otín, Itziar Salaverria, Xose S. Puente, Elias Campo, Sílvia Beà
Journal: Blood
Blood (2019) 133 (9): 940–951.
https://doi.org/10.1182/blood-2018-07-862151
Published: 2019
Includes: Supplemental data
Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3216.
https://doi.org/10.1182/blood-2018-99-116500
Published: 2018
Journal Articles

Phase I Study of Palbociclib Alone and in Combination in Patients with Relapsed and Refractory (R/R) Leukemias

Tapan M. Kadia, MD, Marina Y. Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Christopher B. Benton, MD, William G. Wierda, MD PhD, Prithviraj Bose, MD, Musa E. Yilmaz, MD, Elias J. Jabbour, MD, Steven M. Kornblau, MD, Kapil N. Bhalla, MD, Naveen Pemmaraju, MD, Nitin Jain, MD, Rashmi Malla, RN, BSN, Gautam Borthakur, MD, Jorge E. Cortes, MD, Farhad Ravandi, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4057.
https://doi.org/10.1182/blood-2018-99-117334
Published: 2018
Journal Articles

FOXM1 Controls Leukemia Stem Cell Fate in MLL-Rearranged AML

Yue Sheng, PhD, Chao Hu, PhD, Chunjie Yu, PhD, Rui Ma, Master, Zhijian Qian, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2742.
https://doi.org/10.1182/blood-2018-99-116983
Published: 2018
Journal Articles

Global 3D-Epigenetic Dysregulation of Cyclin D1 and D2 Actively Controls Their Expression Pattern in Multiple Myeloma

Samrat Roy Choudhury, PhD, Cody Ashby, PhD, Ruslana G. Tytarenko, MS, Yan Wang, Purvi Patel, Katie Rose Ryan, PhD, Judith A Dent, Faith E. Davies, MD, Gareth Morgan, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3904.
https://doi.org/10.1182/blood-2018-99-115547
Published: 2018
Journal Articles

Splenic B-Cell Lymphoma/Leukemia, Unclassifiable in Japan

Takaharu Suzuki, MD, Hiroaki Miyoshi, MD PhD, Keisuke Kawamoto, MD PhD, Joji Shimono, MD PhD, Jun Takizawa, MD PhD, Masao Seto, MD PhD, Koichi Ohshima, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5301.
https://doi.org/10.1182/blood-2018-99-113239
Published: 2018