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Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Chibueze A. Ihunnah, PhD, Samit Ghosh, PhD, Scott A. Hahn, MS, Adam C Straub, PhD, Solomon F Ofori-Acquah, PhD

Blood (2016) 128 (22): 1296.

https://doi.org/10.1182/blood.V128.22.1296.1296

Published: 2016

Journal Articles

Endothelin a Receptor (ETR A ) Blockade Inhibits Leukocyte Adhesion to the Vascular Endothelium in Sickle Cell Disease

Haiyan Xiao, PhD, Diana R. Gutsaeva, PhD, Zhen Zheng, MD, Nianlan Yang, MD PhD, Carol Dickerson, MS, James B Parkerson, Shobha Yerigenahally, Songwei Wu, MD, Steffen E. Meiler, MD

Blood (2016) 128 (22): 3635.

https://doi.org/10.1182/blood.V128.22.3635.3635

Published: 2016

Journal Articles

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

Bérengere Koehl, MD, Pierre Nivoit, PhD, Wassim El Nemer, PhD, Catia Pereira, Valentine Brousse, MD, Lea Guyonnet, Anna Chipont, Olivia Lenoir, Malika Benkerrou, MD, Yves Colin Aronovicz, PhD, Pierre-Louis Tharaux, Caroline Le Van Kim, PhD

Blood (2016) 128 (22): 857.

https://doi.org/10.1182/blood.V128.22.857.857

Published: 2016

Journal Articles

Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD

Kaifeng Lisa Lin, LeShara M. Fulton, Matthew Berginski, Michelle L. West, Nicholas A. Taylor, Timothy P. Moran, James M. Coghill, Bruce R. Blazar, James E. Bear, Jonathan S. Serody

Blood (2014) 123 (10): 1604–1614.

https://doi.org/10.1182/blood-2013-09-526020

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Regulation of Endothelin-1-Mediated Reactive Oxygen Species Production by Protein Disulfide Isomerase in Endothelial Cells: Role in Sickle Cell Disease

Patricia Neuman, BS, Gregory N. Prado, PhD, Philip Asamoah, Daphne Diaz, BS, Jose R Romero, PhD, Alicia Rivera, MS, PhD

Blood (2012) 120 (21): 1073.

https://doi.org/10.1182/blood.V120.21.1073.1073

Published: 2012

Journal Articles

Baseline Serum Cytokines Profiles in Mantle Cell Lymphoma Correlates with Outcome

Anthony R Mato, MD, James Greenberg, BS, Mary E Putt, PhD, ScD, K. Stephen Suh, PhD, Yvonne Remache, BA, BSN, Tania Zielonka, RDC, Kathryn Waksmundzki, BS, Ewelina A Protomastro, BA, Susan Stives, APN, Tatyana Feldman, MD, Pritish K. Bhattacharyya, MD, Xiao Yang, M.D. Ph.D, Kar Fai Chow, MD, Alex Campaiola, BSN, Andrew L Pecora, MD, Andre Goy, MD

Blood (2012) 120 (21): 1579.

https://doi.org/10.1182/blood.V120.21.1579.1579

Published: 2012

Journal Articles

Protective Effect of Fetal Hemoglobin On Inflammation-Induced Expression of Hypoxia-Inducible Factor-1α (HIF-1α) in Sickle Mice: Microvascular Implications

Dhananjay K. Kaul, Ph.D., Mary E. Fabry, Ph.D., Sandra M Suzuka, M.S., Janki Shah, M.S.

Blood (2012) 120 (21): 3250.

https://doi.org/10.1182/blood.V120.21.3250.3250

Published: 2012

Journal Articles

Role of Connective Tissue Growth Factor In Endothelin-Mediated Endothelial Cell Activation

Anna J Hernandez, Sonia Henriquez, Enrique R Maldonado, Rodeler Youte, Gregory N Prado, Constanca Coelho, Alicia Rivera, Jose R Romero

Blood (2010) 116 (21): 2107.

https://doi.org/10.1182/blood.V116.21.2107.2107

Published: 2010

Journal Articles

Elevated Tricuspid Regurgitation Jet Velocity on Echocardiogram In Patients with Sickle Cell Disease Is Associated with Worse Steady State Functional Class, Poor Lung Function and Low Haemoglobin but Not Other Markers of Haemolysis or Endothelin-1.

Harpreet Ranu, MBBS, MRCP, BSc, Emma Connell, BSc, PhD, Clare Hunt, BSc, PhD, Frances Boa, MBBS, BSc, PhD, Jayne Lee, BSc, Luise Brown, BSc, Fenella Willis, MBBS, FRCP, MD, FRCPath, Hubertus Buyck, MBChB, PhD, FRACP, FRCPA, Brendan Madden, MBBS, MSc, MD, FRCP, FRCPI

Blood (2010) 116 (21): 1638.

https://doi.org/10.1182/blood.V116.21.1638.1638

Published: 2010

Journal Articles

Natriuretic Peptides as Well as Endothelin, and Not Troponin Are of Value in Early Diagnosis of Acute Cardiotoxicity in Children Undergoing Hematopoietic Stem Cell Transplantation

Agnieszka Zaucha-Prazmo, Katarzyna Drabko, Elzbieta Sadurska, Jerzy R Kowalczyk

Blood (2008) 112 (11): 4300.

https://doi.org/10.1182/blood.V112.11.4300.4300

Published: 2008

Journal Articles

Association of Placenta Growth Factor with Hemolysis and Inflammation in Sickle Cell Disease (SCD)

Kenneth I. Ataga, MD, Susan K Jones, RN, Ben Hulkower, BS, Eugene P. Orringer, MD, Julia E. Brittain, PhD

Blood (2008) 112 (11): 2500.

https://doi.org/10.1182/blood.V112.11.2500.2500

Published: 2008

Journal Articles

Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1α

Nitin Patel, Caryn S. Gonsalves, Punam Malik, Vijay K. Kalra

Blood (2008) 112 (3): 856–865.

https://doi.org/10.1182/blood-2007-12-130567

Published: 2008

Journal Articles

High Efficiency Retro- and Lentiviral Transduction of Blood Endothelial Outgrowth Cells

Marcus A. Stockschlaeder, MD, Olga Shardakova, MD, Boris Fehse, PhD, Rudiger E. Scharf, MD

Blood (2007) 110 (11): 3727.

https://doi.org/10.1182/blood.V110.11.3727.3727

Published: 2007

Journal Articles

Plasma Endothelin-1 and Leukocyte Microparticles Increase during Pain Episode in Patients with Sickle Cell Disease.

Ofelia Alvarez, MD, Joaquin Jimenez, MD, Mary Donovan, RN, Gabriela Lopez-Mitnik, MS, Carlos Bidot, MD, Wenche Jy, PhD, Loreta Bidot, BS, Lawrence Horstman, BS, Yeon-Soong Ahn, MD

Blood (2007) 110 (11): 3807.

https://doi.org/10.1182/blood.V110.11.3807.3807

Published: 2007

Journal Articles

Pulmonary Hypertension after Thalidomide Administration in Multiple Myeloma Patients. Pilot Study.

Christos Lafaras, PhD, Eudokia Mandala, PhD, Eugenia Verrou, MD, Dimitrios Platogiannis, PhD, Kostas Zervas, PhD, Theodoros Bischiniotis, PhD, George Ilonidis

Blood (2007) 110 (11): 4846.

https://doi.org/10.1182/blood.V110.11.4846.4846

Published: 2007

Journal Articles

Arginine Diet for Sickle Transgenic Mice Reduces Endothelin-1-Stimulated Gardos Channel Activity.

Jose R. Romero, Alicia Rivera, Adriana Muñiz, Ronald Nagel, Mary E. Fabry

Blood (2007) 110 (11): 3399.

https://doi.org/10.1182/blood.V110.11.3399.3399

Published: 2007

Journal Articles

The Dual Endothelin Receptor Antagonist Bosentan Prevents the Acute Sickle Cell-Related Hypoxic Lung and Kidney Injury in Transgenic SAD Mice.

Nathalie Sabaa, Lucia de Franceschi, Philippe Bonnin, Giorgio Malpeli, Stéphane Germain, Sophie Vandermeersch, Micheline Maier-Redelsperger, Aldo Scarpa, Anne Janin, Bernard Levy, Robert Girot, Yves Beuzard, Christophe Leboeuf, Annick Henri, Jean-Claude Dussaule, Pierre-Louis Tharaux

Blood (2006) 108 (11): 687.

https://doi.org/10.1182/blood.V108.11.687.687

Published: 2006

Journal Articles

Hypoxia-Inducible Factor (HIF-1alpha) Has a Crucial Role in Microvascular Regulation in Transgenic/Knockout Sickle Mouse Models.

Dhananjay K. Kaul, PhD, Xiao-du Liu, MD, Xiaoqin Zhang, MS, Ronald L. Nagel, MD, Mary E. Fabry, PhD

Blood (2006) 108 (11): 690.

https://doi.org/10.1182/blood.V108.11.690.690

Published: 2006

NARROW

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Endothelin a Receptor (ETR A ) Blockade Inhibits Leukocyte Adhesion to the Vascular Endothelium in Sickle Cell Disease

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD

Regulation of Endothelin-1-Mediated Reactive Oxygen Species Production by Protein Disulfide Isomerase in Endothelial Cells: Role in Sickle Cell Disease

Baseline Serum Cytokines Profiles in Mantle Cell Lymphoma Correlates with Outcome

Protective Effect of Fetal Hemoglobin On Inflammation-Induced Expression of Hypoxia-Inducible Factor-1α (HIF-1α) in Sickle Mice: Microvascular Implications

Role of Connective Tissue Growth Factor In Endothelin-Mediated Endothelial Cell Activation

Elevated Tricuspid Regurgitation Jet Velocity on Echocardiogram In Patients with Sickle Cell Disease Is Associated with Worse Steady State Functional Class, Poor Lung Function and Low Haemoglobin but Not Other Markers of Haemolysis or Endothelin-1.

Natriuretic Peptides as Well as Endothelin, and Not Troponin Are of Value in Early Diagnosis of Acute Cardiotoxicity in Children Undergoing Hematopoietic Stem Cell Transplantation

Association of Placenta Growth Factor with Hemolysis and Inflammation in Sickle Cell Disease (SCD)

Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1α

High Efficiency Retro- and Lentiviral Transduction of Blood Endothelial Outgrowth Cells

Plasma Endothelin-1 and Leukocyte Microparticles Increase during Pain Episode in Patients with Sickle Cell Disease.

Pulmonary Hypertension after Thalidomide Administration in Multiple Myeloma Patients. Pilot Study.

Arginine Diet for Sickle Transgenic Mice Reduces Endothelin-1-Stimulated Gardos Channel Activity.

The Dual Endothelin Receptor Antagonist Bosentan Prevents the Acute Sickle Cell-Related Hypoxic Lung and Kidney Injury in Transgenic SAD Mice.

Hypoxia-Inducible Factor (HIF-1alpha) Has a Crucial Role in Microvascular Regulation in Transgenic/Knockout Sickle Mouse Models.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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