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Journal Articles

Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia

Laurent Kiger, Sandia Adypagavane, Laura Bencheikh, PhD, Nicolas Hebert, Stephane Moutereau, MD, Frédéric Galactéros, MD PhD, Michael Marden, PhD, Yves Beuzard, MD, France Pirenne, MD PhD, Pablo Bartolucci, MD PhD

Blood (2019) 134 (Supplement_1): 3381.

https://doi.org/10.1182/blood-2019-130600

Published: 2019

Journal Articles

Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy

Blood (2017) 130 (Supplement 1): 4609.

https://doi.org/10.1182/blood.V130.Suppl_1.4609.4609

Published: 2017

Journal Articles

Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies

Blood (2016) 128 (22): 2311.

https://doi.org/10.1182/blood.V128.22.2311.2311

Published: 2016

Journal Articles

Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector

Blood (2015) 126 (23): 202.

https://doi.org/10.1182/blood.V126.23.202.202

Published: 2015

Journal Articles

Study Hgb-205: Outcomes of Gene Therapy for Hemoglobinopathies Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral β Α-T87Q -Globin Vector (LentiGlobin ® BB305 Drug Product)

Blood (2014) 124 (21): 4797.

https://doi.org/10.1182/blood.V124.21.4797.4797

Published: 2014

Journal Articles

Modulation of Activin Signaling by RAP-011 (ActRIIA-IgG1) Improve Anemia, Increases Hemoglobin Levels and Corrects Ineffective Erythropoiesis in β-Thalassemia

Michael Dussiot, Thiago Maciel, PhD, Aurelie Fricot, Joel Veiga, Etienne Paubelle, Emmanuel Payen, Yves Beuzard, MD, Jean-Antoine Ribeil, MD, PhD, Jean-Benoît Arlet, MD, Genevieve Courtois, PhD, Tom O Daniel, MD, PhD, Rajesh Chopra, MD, PhD, Victoria Sung, Ph.D., Olivier Hermine, MD, PhD, Ivan Cruz Moura, PhD

Blood (2012) 120 (21): 247.

https://doi.org/10.1182/blood.V120.21.247.247

Published: 2012

Journal Articles

Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion

Olivier Negre, Floriane Fusil, Charlotte Colomb, Shoshannah Roth, Beatrix Gillet-Legrand, Annie Henri, Yves Beuzard, Frederic Bushman, Philippe Leboulch, Emmanuel Payen

Blood (2011) 117 (20): 5321–5331.

https://doi.org/10.1182/blood-2010-01-263582

Published: 2011

Includes: Supplemental data

Journal Articles

Phosphodiesterase-4 Inhibition Reduces Ischemic/Reperfusion Liver Injury in a Mouse Model for Sickle Cell Disease.

Alida Filippini, Giorgio Malpeli, Anne Janin, Orah S Platt, Christhope Leboeuf, Aldo Scarpa, Yves Beuzard, Lucia De Franceschi, MD

Blood (2008) 112 (11): 1444.

https://doi.org/10.1182/blood.V112.11.1444.1444

Published: 2008

Journal Articles

Heat-Shock Protein-70, -27 and Peroxiredoxin-2 Show Chaperone Function in Sickle Red Cells: Evidences from Transgenic Sickle Cell Mouse Model.

Andrea Biondani, PhD, Franco Turrini, MD, Alessandro Matte’, Franco Carta, PhD, Alida Filippini, MD, Yves Beuzard, MD, Lucia De Franceschi, MD

Blood (2007) 110 (11): 845.

https://doi.org/10.1182/blood.V110.11.845.845

Published: 2007

Journal Articles

The Dual Endothelin Receptor Antagonist Bosentan Prevents the Acute Sickle Cell-Related Hypoxic Lung and Kidney Injury in Transgenic SAD Mice.

Nathalie Sabaa, Lucia de Franceschi, Philippe Bonnin, Giorgio Malpeli, Stéphane Germain, Sophie Vandermeersch, Micheline Maier-Redelsperger, Aldo Scarpa, Anne Janin, Bernard Levy, Robert Girot, Yves Beuzard, Christophe Leboeuf, Annick Henri, Jean-Claude Dussaule, Pierre-Louis Tharaux

Blood (2006) 108 (11): 687.

https://doi.org/10.1182/blood.V108.11.687.687

Published: 2006

Journal Articles

PDE-4 Inhibitor Rolipram Prevents Hypoxia Induced Pulmonary Hypertension in Transgenic Sickle Cell Sad Mice.

Lucia De Franceschi, MD, Giorgio Malpeli, Anne Janin, MD, Aldo Scarpa, MD, Christhophe Leboeuf, Orah Platt, MD, Philippe Leboulch, Emmanuel Payen, Yves Beuzard, MD, Carlo Brugnara, MD

Blood (2004) 104 (11): 3577.

https://doi.org/10.1182/blood.V104.11.3577.3577

Published: 2004

Journal Articles

Protective Effects of No-Albumin and Albumin on Lung Injury Induced by Hypoxia/Reoxygenation in a Mouse Model of Sickle Cell Disease.

Lucia De Franceschi, MD, Giorgio Malpeli, Anne Janin, MD, Eva Muchitsch, Aldo Scarpa, MD, Philippe Leboulch, Christhope Leboeuf, Yves Beuzard, MD, Carlo Brugnara, MD

Blood (2004) 104 (11): 3580.

https://doi.org/10.1182/blood.V104.11.3580.3580

Published: 2004

Journal Articles

Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease–specific lung injury induced by hypoxia/reoxygenation

Lucia de Franceschi, Antonella Baron, Aldo Scarpa, Christophe Adrie, Anne Janin, Stefano Barbi, Jean Kister, Philippe Rouyer-Fessard, Roberto Corrocher, Philippe Leboulch, Yves Beuzard

Blood (2003) 102 (3): 1087–1096.

https://doi.org/10.1182/blood-2002-07-2135

Published: 2003

Journal Articles

ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice

Jonathan W. Stocker, Lucia De Franceschi, Grant A. McNaughton-Smith, Roberto Corrocher, Yves Beuzard, Carlo Brugnara

Blood (2003) 101 (6): 2412–2418.

https://doi.org/10.1182/blood-2002-05-1433

Published: 2003

Journal Articles

Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo

Bruno Dalle, Annie Henri, Philippe Rouyer-Fessard, Mickaël Bettan, Daniel Scherman, Yves Beuzard, Emmanuel Payen

Blood (2001) 97 (12): 3776–3782.

https://doi.org/10.1182/blood.V97.12.3776

Published: 2001

Journal Articles

Formation of Dense Erythrocytes in SAD Mice Exposed to Chronic Hypoxia: Evaluation of Different Therapeutic Regimens and of a Combination of Oral Clotrimazole and Magnesium Therapies

Lucia De Franceschi, Carlo Brugnara, Philippe Rouyer-Fessard, Helene Jouault, Yves Beuzard

Blood (1999) 94 (12): 4307–4313.

https://doi.org/10.1182/blood.V94.12.4307

Published: 1999

Journal Articles

Dietary Magnesium Supplementation Ameliorates Anemia in a Mouse Model of β-Thalassemia

Lucia De Franceschi, Carlo Brugnara, Yves Beuzard

Blood (1997) 90 (3): 1283–1290.

https://doi.org/10.1182/blood.V90.3.1283

Published: 1997

NARROW

Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia

Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy

Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies

Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector

Study Hgb-205: Outcomes of Gene Therapy for Hemoglobinopathies Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral β Α-T87Q -Globin Vector (LentiGlobin ® BB305 Drug Product)

Modulation of Activin Signaling by RAP-011 (ActRIIA-IgG1) Improve Anemia, Increases Hemoglobin Levels and Corrects Ineffective Erythropoiesis in β-Thalassemia

Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion

Phosphodiesterase-4 Inhibition Reduces Ischemic/Reperfusion Liver Injury in a Mouse Model for Sickle Cell Disease.

Heat-Shock Protein-70, -27 and Peroxiredoxin-2 Show Chaperone Function in Sickle Red Cells: Evidences from Transgenic Sickle Cell Mouse Model.

The Dual Endothelin Receptor Antagonist Bosentan Prevents the Acute Sickle Cell-Related Hypoxic Lung and Kidney Injury in Transgenic SAD Mice.

PDE-4 Inhibitor Rolipram Prevents Hypoxia Induced Pulmonary Hypertension in Transgenic Sickle Cell Sad Mice.

Protective Effects of No-Albumin and Albumin on Lung Injury Induced by Hypoxia/Reoxygenation in a Mouse Model of Sickle Cell Disease.

Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease–specific lung injury induced by hypoxia/reoxygenation

ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice

Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo

Formation of Dense Erythrocytes in SAD Mice Exposed to Chronic Hypoxia: Evaluation of Different Therapeutic Regimens and of a Combination of Oral Clotrimazole and Magnesium Therapies

Dietary Magnesium Supplementation Ameliorates Anemia in a Mouse Model of β-Thalassemia

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American Society of Hematology

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