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Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

A little bit of kindlin goes a long way

Joel S. Bennett
Journal: Blood
Blood (2015) 126 (24): 2535–2536.
https://doi.org/10.1182/blood-2015-10-675454
Published: 2015
Journal Articles

Analysis of β3 Binding to the c-Src SH3 Domain

Patrik Nygren, Ph.D., Lisa M. Span, David T. Moore, M.D, Ph.D, Hong Cheng, Ph.D., Heinrich Roder, PhD, William F. DeGrado, Ph.D., Joel S. Bennett, M.D.
Journal: Blood
Blood (2012) 120 (21): 383.
https://doi.org/10.1182/blood.V120.21.383.383
Published: 2012
Journal Articles

Kindlin-3 Undergoes Endoproteolysis in Stored Platelets and After Platelet Stimulation

Craig N. Streu, Ph.D., Patrik Nygren, Ph.D., Paul C. Billings, Ph.D., David T. Moore, B.S., M.S., Kathleen S. Molnar, B.S.E., William F. DeGrado, Ph.D., Joel S. Bennett, M.D.
Journal: Blood
Blood (2011) 118 (21): 1255.
https://doi.org/10.1182/blood.V118.21.1255.1255
Published: 2011
Journal Articles

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Natalina E. Elliott, Susan M. Cleveland, Victor Grann, John Janik, Thomas A. Waldmann, Utpal P. Davé
Journal: Blood
Blood (2011) 118 (14): 3911–3921.
https://doi.org/10.1182/blood-2010-12-319467
Published: 2011
Includes: Supplemental data
Journal Articles

ALL-Associated JAK1 Mutations Confer Hypersensitivity to the Anti-Proliferative Effect of Type I Interferon.

Tekla Hornakova, Sabina Chiaretti, Muriel Lemaire, Robin Foà, Marco Tartaglia, Jean-Christophe Renauld, Laurent Knoops
Journal: Blood
Blood (2009) 114 (22): 3066.
https://doi.org/10.1182/blood.V114.22.3066.3066
Published: 2009
Journal Articles

ALL-Associated JAK1 Mutants Activate the JAK/STAT Pathway Via IL-9Rα Homodimers

Tekla Hornakova, Judith Staerk, Yohan Royer, Elisabetta Flex, Marco Tartaglia, Stefan N. Constantinescu, MD, PhD, Jean-Christophe Renauld, Laurent Knoops
Journal: Blood
Blood (2008) 112 (11): 2848.
https://doi.org/10.1182/blood.V112.11.2848.2848
Published: 2008
Journal Articles

The Jak2 V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes

Gerlinde Wernig, Jeffrey R. Gonneville, Brian J. Crowley, Margret S. Rodrigues, Mamatha M. Reddy, Heidi E. Hudon, Christoph Walz, Andreas Reiter, Klaus Podar, Yohan Royer, Stefan N. Constantinescu, Michael H. Tomasson, James D. Griffin, D. Gary Gilliland, Martin Sattler
Journal: Blood
Blood (2008) 111 (7): 3751–3759.
https://doi.org/10.1182/blood-2007-07-102186
Published: 2008
Journal Articles

Essential Role of Kindlin 3 in Zebrafish Thrombopoiesis.

James J. Mann, PhD, Nathaniel B. Langer, BS, Andrew Woo, PhD, Tyler B. Moran, BS, Yocheved Schindler, BS, Matthew Sullivan, BA, Barry H. Paw, MD PhD, Alan B. Cantor, MD PhD
Journal: Blood
Blood (2006) 108 (11): 1166.
https://doi.org/10.1182/blood.V108.11.1166.1166
Published: 2006
Journal Articles

The Jak2 V617F Oncogene Associated with Polycythemia Vera Requires a Functional FERM Domain for Transformation and for Expression of the Myc and Pim Proto-Oncogenes.

Martin Sattler, PhD, Brian J. Crowley, Jeffrey R. Gonneville, Jeremy Ho, Heidi H. Hudon, Klaus Podar, M.D., Ph.D., Yohan Royer, Stefan N. Constantinescu, M.D., Ph.D., James D. Griffin, M.D.
Journal: Blood
Blood (2006) 108 (11): 3611.
https://doi.org/10.1182/blood.V108.11.3611.3611
Published: 2006
Journal Articles

Overexpression of Jak Kinases Promotes In Vitro Transformation.

Laurent Knoops, MD, Yohan Royer, PhD, Stefan Constantinescu, MD, PhD, Jean-Christophe Renauld, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 4325.
https://doi.org/10.1182/blood.V104.11.4325.4325
Published: 2004