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Journal Articles

Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations

Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Charu Mehta, MS, Kyle J Hewitt, PhD, Alexandra Soukup, PhD, Isabela J Fraga de Andrade, Bachelors in Biological Science, Erik A. Ranheim, MD PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 2519.

https://doi.org/10.1182/blood-2019-129447

Published: 2019

Journal Articles

Integrated Anemia Detection and Hemoglobin Variant Identification Using Point-of-Care Microchip Electrophoresis

Ran An, PhD, Muhammad Noman Hasan, MS, Yuncheng Man, Umut A. Gurkan, PhD

Blood (2019) 134 (Supplement_1): 378.

https://doi.org/10.1182/blood-2019-126096

Published: 2019

Journal Articles

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

Taishi Yonezawa, MSc, Hirotaka Takahasi, PhD, Tatsuya Sawasaki, PhD, Toshio Kitamura, MD PhD, Susumu Goyama, MD PhD

Blood (2019) 134 (Supplement_1): 1252.

https://doi.org/10.1182/blood-2019-126264

Published: 2019

Journal Articles

The Impact of PHF6 Mutations in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

Kelly S. Chien, MD, Rashmi Kanagal-Shamanna, MD, Kiran Naqvi, MDMPH, Koji Sasaki, MD, Yesid Alvarado, MD, Koichi Takahashi, MD, Tapan M. Kadia, MD, Gautam M. Borthakur, MD, Elias Jabbour, MD, Mark Routbort, MD PhD, Sherry A. Pierce, BSN, BA, Kelly Soltysiak, PhD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD, Guillermo Montalban-Bravo, MD

Blood (2019) 134 (Supplement_1): 1436.

https://doi.org/10.1182/blood-2019-131188

Published: 2019

Journal Articles

Hydroxyurea Pharmacokinetic Profiles in Children Treated for Extreme Thrombocytosis after Total Pancreatectomy with Islet Cell Autotransplant Demonstrate Poor Absorption

Alexander A Boucher, MD, Min Dong, PhD, Anu Marahatta, PhD, Adriane Hausfeld, Thad A. Howard, MS, Jaimie D Nathan, MD, Alexander A. Vinks, PharmD, PhD FCP, Patrick T. McGann, MD, Russell E. Ware, MD PhD, Lori Luchtman-Jones, MD

Blood (2019) 134 (Supplement_1): 4893.

https://doi.org/10.1182/blood-2019-127378

Published: 2019

Journal Articles

High Levels of Peripheral Vasoconstriction Detected By Polysomnography Predict More Acute Severe Pain Episodes in Children with Sickle Cell Anemia

Patjanaporn Chalacheva, PhD, Yunhua Ji, MS, Carol L. Rosen, MD, Michael R. DeBaun, MDMPH, Michael C.K. Khoo, PhD, Thomas Coates, MD

Blood (2019) 134 (Supplement_1): 894.

https://doi.org/10.1182/blood-2019-121944

Published: 2019

Journal Articles

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

Ruopeng Feng, PhD, Phillip A Doerfler, PhD, Yu Yao, MD, Xing Tang, PhD, Yong-Dong Wang, PhD, Chunliang Li, PhD, David E. Root, PhD, Yong Cheng, PhD, Mitchell J. Weiss, MD PhD

Blood (2018) 132 (Supplement 1): 410.

https://doi.org/10.1182/blood-2018-99-115589

Published: 2018

Journal Articles

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Blood (2018) 132 (Supplement 1): 211.

https://doi.org/10.1182/blood-2018-99-116411

Published: 2018

Journal Articles

Hematologic Malignancies Arising in Patients with Germ Cell Tumors: Secondary Somatic Differentiation of Hematopoietic Malignancies from Germ Cell Precursors

Justin Taylor, MD, Mark Donoghue, PhD, Raajit K. Rampal, MD PhD, Roni Tamari, MD, Martin S. Tallman, MD, Darren R. Feldman, MD, Barry S Taylor, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 87.

https://doi.org/10.1182/blood-2018-99-111976

Published: 2018

Journal Articles

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Meiling May, BA, Stephen Desiderio, MD PhD, John Thomas Bettridge, BA

Blood (2018) 132 (Supplement 1): 512.

https://doi.org/10.1182/blood-2018-99-116675

Published: 2018

Journal Articles

Role of KDM2B and Non-Canonical PRC1.1 As a Tumor Suppressor in T-ALL

Yusuke Isshiki, MD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Kazumasa Aoyama, PhD, Atsunori Saraya, Emiko Sakaida, MD PhD, Chiaki Nakaseko, MD PhD, Koutaro Yokote, MD PhD, Haruhiko Koseki, PhD, Atsushi Iwama, MD PhD

Blood (2018) 132 (Supplement 1): 2597.

https://doi.org/10.1182/blood-2018-99-117831

Published: 2018

Journal Articles

Clinical Testing of Hemechip in Nigeria for Point-of-Care Screening of Sickle Cell Disease

Muhammad Noman Hasan, MS, Arwa Fraiwan, PhD, Priyaleela Thota, MD, Tolulope Oginni, BS, Grace Mfon Olanipekun, Fatimah Hassan-Hanga, MD, Jane Little, MD, Stephen K. Obaro, MD PhD, Umut A. Gurkan, PhD

Blood (2018) 132 (Supplement 1): 1095.

https://doi.org/10.1182/blood-2018-99-115355

Published: 2018

Journal Articles

A Novel Device Suitable for Home Monitoring of White Blood Cell and Neutrophil Counts

David C Dale, MD, Merideth L. Kelley, MSc, Myriam Navarro-De La Vega, Dhruv Parthasarathy, Deepika Bodapati, Louis Virey, MSc, Steve Moffatt, BSc, Tanay Tandon

Blood (2018) 132 (Supplement 1): 1103.

https://doi.org/10.1182/blood-2018-99-112647

Published: 2018

Journal Articles

Impact of Inotersen on Functioning and Activities of Daily Living for Patients with Hereditary TTR Amyloidosis: Results from a Double-Blind Placebo-Controlled Trial

Aaron Yarlas, PhD, Giampaolo Merlini, MD, Michelle K White, PhD, Asia Sikora Kessler, PhD, Andrew Lovley, MA, Spencer D Guthrie, MPH, MBA, Michael Pollock, Morie A. Gertz, MD

Blood (2018) 132 (Supplement 1): 4812.

https://doi.org/10.1182/blood-2018-99-119578

Published: 2018

Journal Articles

Successful Simultaneous Screening of Sickle Cell Disease, HIV and Tuberculosis in Rural Guinea Bissau, West Africa through Rapid Tests and a Standardized Clinical Questionnaire: An Outreach Program Due to a Public-Private Partnership

Federica Menzato, MD, Luca Bosa, MD, Armando Sifna, MD, Luisa Da Silva, MD, Elena Gasperoni, Maddalena Martella, Mamadu Saliu Sanha, Alfa Mustik, Liviana Da Dalt, Prof., Fabio Riccardi, MD, Raffaella Colombatti, MD PhD

Blood (2018) 132 (Supplement 1): 4715.

https://doi.org/10.1182/blood-2018-99-119006

Published: 2018

Journal Articles

Insufficiency of Non-Canonical PRC1 Complex Cooperates with an Activating JAK2 Mutation in the Pathogenesis of Myelofibrosis

Daisuke Shinoda, MD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Atsunori Saraya, Hironori Harada, MD PhD, Haruhiko Koseki, PhD, Kazuya Shimoda, MD PhD, Goro Sashida, MD PhD, Atsushi Iwama, MD PhD

Blood (2018) 132 (Supplement 1): 100.

https://doi.org/10.1182/blood-2018-99-117741

Published: 2018

Journal Articles

Novel Therapeutic Targeting of UHRF1 Restores 5'-Azacytidine Response in Resistant Acute Myeloid Leukemia

Anup Kumar Singh, MS, PhD, Xiaochun Yu, MD PhD

Blood (2018) 132 (Supplement 1): 1356.

https://doi.org/10.1182/blood-2018-99-115735

Published: 2018

Journal Articles

Importance of Transcription Factor Nrf2 for Cereblon Expression and Clinical Response to Combination of Lenalidomide and Erythropoietin in Lower-Risk Myelodysplastic Syndromes

Radka Bokorová, MSc, Jaroslav Polak, MSc, Anna Jonasova, MD, Radana Neuwirtova, MD PhD, Marie Lauermannova, MD, Jaroslav Cermak, MD PhD, Marketa Stastna, MD PhD, Cyril Salek, Dana Mikulenkova, MD, Zuzana Zemanova, PhD, Jana Brezinova, Kyra Michalova, PhD, Denisa Myslivcova, PhD, Ota Fuchs, PhD

Blood (2018) 132 (Supplement 1): 5507.

https://doi.org/10.1182/blood-2018-99-115803

Published: 2018

Journal Articles

A Single Intravenous Infusion of FLT180a Results in Factor IX Activity Levels of More Than 40% and Has the Potential to Provide a Functional Cure for Patients with Haemophilia B

Pratima Chowdary, MD, Susie Shapiro, MD, Andrew M. Davidoff, MD, Ulrike Reiss, MD, Rebecca Alade, PhD, Geoff Brooks, BSc, Allison Dane, PhD, Jenny McIntosh, PhD, Gerard Short, MBBS, Edward Tuddenham, MD, Amit C Nathwani, MD PhD

Blood (2018) 132 (Supplement 1): 631.

https://doi.org/10.1182/blood-2018-99-118050

Published: 2018

Journal Articles

Hemechip: An Automated Portable Microchip Electrophoresis Platform for Point-of-Care Sickle Cell Disease Screening

Muhammad Noman Hasan, MS, Arwa Fraiwan, PhD, Jane A. Little, MD, Umut A. Gurkan, PhD

Blood (2017) 130 (Supplement 1): 3519.

https://doi.org/10.1182/blood.V130.Suppl_1.3519.3519

Published: 2017

NARROW

Loss-of-Function and Gain-of-Function Consequences of GATA2 Disease Mutations

Integrated Anemia Detection and Hemoglobin Variant Identification Using Point-of-Care Microchip Electrophoresis

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

The Impact of PHF6 Mutations in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

Hydroxyurea Pharmacokinetic Profiles in Children Treated for Extreme Thrombocytosis after Total Pancreatectomy with Islet Cell Autotransplant Demonstrate Poor Absorption

High Levels of Peripheral Vasoconstriction Detected By Polysomnography Predict More Acute Severe Pain Episodes in Children with Sickle Cell Anemia

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Hematologic Malignancies Arising in Patients with Germ Cell Tumors: Secondary Somatic Differentiation of Hematopoietic Malignancies from Germ Cell Precursors

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Role of KDM2B and Non-Canonical PRC1.1 As a Tumor Suppressor in T-ALL

Clinical Testing of Hemechip in Nigeria for Point-of-Care Screening of Sickle Cell Disease

A Novel Device Suitable for Home Monitoring of White Blood Cell and Neutrophil Counts

Impact of Inotersen on Functioning and Activities of Daily Living for Patients with Hereditary TTR Amyloidosis: Results from a Double-Blind Placebo-Controlled Trial

Successful Simultaneous Screening of Sickle Cell Disease, HIV and Tuberculosis in Rural Guinea Bissau, West Africa through Rapid Tests and a Standardized Clinical Questionnaire: An Outreach Program Due to a Public-Private Partnership

Insufficiency of Non-Canonical PRC1 Complex Cooperates with an Activating JAK2 Mutation in the Pathogenesis of Myelofibrosis

Novel Therapeutic Targeting of UHRF1 Restores 5'-Azacytidine Response in Resistant Acute Myeloid Leukemia

Importance of Transcription Factor Nrf2 for Cereblon Expression and Clinical Response to Combination of Lenalidomide and Erythropoietin in Lower-Risk Myelodysplastic Syndromes

A Single Intravenous Infusion of FLT180a Results in Factor IX Activity Levels of More Than 40% and Has the Potential to Provide a Functional Cure for Patients with Haemophilia B

Hemechip: An Automated Portable Microchip Electrophoresis Platform for Point-of-Care Sickle Cell Disease Screening

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American Society of Hematology

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