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Alexander A. Vinks
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Journal Articles

Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis

Alina Sadaf, Min Dong, Jennifer Korpik, Amanda Pfeiffer, Theodosia A. Kalfa, Teresa S. Latham, Alexander A. Vinks, Russell E. Ware, Charles T. Quinn
Journal: Blood
Blood (2023) 142 (Supplement 1): 1145.
https://doi.org/10.1182/blood-2023-180312
Published: 2023
Journal Articles

Hydroxyurea Pharmacokinetics in Young Children with Sickle Cell Anemia: Results from the Therapeutic Response Evaluation and Adherence Trial (TREAT)

Min Dong, Angela Good, Alexander A. Vinks, Russell E. Ware, Patrick T. McGann
Journal: Blood
Blood (2022) 140 (Supplement 1): 8168–8169.
https://doi.org/10.1182/blood-2022-171022
Published: 2022
Journal Articles

Hydroxyurea Pharmacokinetics and Fetal Hemoglobin Response in Ugandan Children with Sickle Cell Anemia

Alexandra Power-Hays, Min Dong, Kathryn McElhinney, Andrea L. Conroy, Teresa Latham, Adam Lane, Robert O. Opoka, Alexander A. Vinks, Russell E. Ware
Journal: Blood
Blood (2022) 140 (Supplement 1): 5461–5462.
https://doi.org/10.1182/blood-2022-170839
Published: 2022
Journal Articles

Evaluation of Dosage and Food Effect on L-Glutamine Exposure for Sickle Cell Anemia: A Population Pharmacokinetic Analysis

Min Dong, Alina Sadaf, Alexander A. Vinks, Russell E. Ware, Charles T. Quinn
Journal: Blood
Blood (2022) 140 (Supplement 1): 8256–8257.
https://doi.org/10.1182/blood-2022-167550
Published: 2022
Journal Articles

Pharmacokinetics of L-Glutamine (Endari) in Pediatric and Adult Sickle Cell Disease Patients: A Phase 4, Open-Label, Single-Center Study

Alina Sadaf, Min Dong, Amanda Pfeiffer, Teresa Latham, Alexander A. Vinks, Russell E. Ware, Charles T. Quinn
Journal: Blood
Blood (2021) 138 (Supplement 1): 980.
https://doi.org/10.1182/blood-2021-147631
Published: 2021
Journal Articles

V2 Trial: A Phase I Study of Venetoclax Combined with CPX-351 for Children, Adolescents and Young Adults with Relapsed or Refractory Acute Leukemia

Laura Agresta, MD, Maureen M O'Brien, MD, Kana Mizuno, PhD, Robin Norris, MD MS, MPH, Erin H. Breese, MD PhD, Christine L Phillips, MD, Karen Burns, MD, Benjamin Mizukawa, Lynn Lee, MD, Adam Lane, PhD, Robert B. Lorsbach, MD PhD, Thomas D. Ryan, MD PhD, Pankaj B. Desai, PhD, Alexander A. Vinks, PharmD, PhD, H. Leighton Grimes, PhD, John P Perentesis, Michael J. Absalon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3830.
https://doi.org/10.1182/blood-2019-121514
Published: 2019
Journal Articles

Hydroxyurea Pharmacokinetic Profiles in Children Treated for Extreme Thrombocytosis after Total Pancreatectomy with Islet Cell Autotransplant Demonstrate Poor Absorption

Alexander A Boucher, MD, Min Dong, PhD, Anu Marahatta, PhD, Adriane Hausfeld, Thad A. Howard, MS, Jaimie D Nathan, MD, Alexander A. Vinks, PharmD, PhD FCP, Patrick T. McGann, MD, Russell E. Ware, MD PhD, Lori Luchtman-Jones, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4893.
https://doi.org/10.1182/blood-2019-127378
Published: 2019
Journal Articles

Clinical and Laboratory Benefits of Early Initiation of Hydroxyurea with Pharmacokinetic Guided Dosing for Young Children with Sickle Cell Anemia

Patrick T. McGann, MD, Omar Niss, MD, Min Dong, PhD, Anu Marahatta, PhD, Tomoyuki Mizuno, PhD, Karen Kalinyak, MD, Theodosia A. Kalfa, MD PhD, Punam Malik, MD, Charles T. Quinn, MD, Russell E. Ware, MD PhD, Alexander A. Vinks, PharmD, PhD FCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 507.
https://doi.org/10.1182/blood-2018-99-112909
Published: 2018
Journal Articles

Hydroxyurea Exposure in Lactation—a Pharmacokinetics Study (HELPS)

Russell E. Ware, MD PhD, Anu Marahatta, PhD, Julie L Ware, MD MPH, Kathryn L McElhinney, BS, Min Dong, PhD, Alexander A. Vinks, PharmD, PhD FCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 3677.
https://doi.org/10.1182/blood-2018-99-114142
Published: 2018
Journal Articles

Personalized Hydroxyurea Dosing to Reduce Time to MTD and Optimize the HbF Response: Results from the TREAT Study

Patrick T. McGann, MD MS, Omar Niss, MD, Min Dong, PhD, Anu Marahatta, PhD, Kathryn L McElhinney, BS, Thad A. Howard, MS, Tomoyuki Mizuno, PhD, Theodosia A. Kalfa, MD PhD, Karen Kalinyak, MD, Punam Malik, MD, Charles T. Quinn, MD MS, Russell E. Ware, MD PhD, Alexander A. Vinks, PharmD, PhD FCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 615.
https://doi.org/10.1182/blood.V130.Suppl_1.615.615
Published: 2017
Journal Articles

Quercetin: A Novel Targeted Chemoprevention for Patients with Fanconi Anemia (FA)

Parinda A Mehta, MD, Tsuyoshi Fukuda, Junfang Zhao, Cancelas-Perez Jose, Sara Loveless, BSN, Kenneth Setchell, Alexander A. Vinks, Qishen Pang, Deborah Elder, Susan Rose, Kasiani C. Myers, MD, Adam S. Nelson, Stephanie Edwards, Adam Lane, Stella M Davies
Journal: Blood
Blood (2017) 130 (Supplement 1): 1178.
https://doi.org/10.1182/blood.V130.Suppl_1.1178.1178
Published: 2017
Journal Articles

Pharmacokinetics of Hydroxyurea Therapy in African Children with Sickle Cell Anemia:Â Noharm Ancillary PK Study

Anu Marahatta, PhD, Min Dong, PhD, Robert Opoka, Kathryn E. McElhinney, Teresa S. Latham, Chandy C. John, MDMS, Alexander A. Vinks, Russell E. Ware, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2252.
https://doi.org/10.1182/blood.V130.Suppl_1.2252.2252
Published: 2017
Journal Articles

Individualized Dosing of Hydroxyurea for Children with Sickle Cell Anemia Using a Population Pharmacokinetic-Based Model: The TREAT Study

Patrick T. McGann, MD MS, Min Dong, PhD, Anu Marahatta, PhD, Thad A. Howard, MS, Tomoyuki Mizuno, PhD, Karen A. Kalinyak, MD, Theodosia A. Kalfa, MD PhD, Punam Malik, MD, Omar Niss, MD, Charles T Quinn, MD, Russell E. Ware, MD PhD, Alexander A. Vinks, PharmD, PhD
Journal: Blood
Blood (2016) 128 (22): 3652.
https://doi.org/10.1182/blood.V128.22.3652.3652
Published: 2016
Journal Articles

Precision Dosing of Alemtuzumab: Population Pharmacokinetic Modeling in Pediatric Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Non-Malignant Diseases

Tsuyoshi Fukuda, PhD, Chie Emoto, PhD, Rebecca A Marsh, MD, Lisa Neumeier, BS, Alexander A. Vinks, PharmD, PhD, Parinda A Mehta, MD
Journal: Blood
Blood (2016) 128 (22): 2203.
https://doi.org/10.1182/blood.V128.22.2203.2203
Published: 2016
Journal Articles

Pharmacokinetics-Based Individualized Dosing Strategy to Predict Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Patrick T. McGann, MD MS, Min Dong, PhD, Russell E. Ware, MD PhD, Alexander A Vinks, PharmD, PhD
Journal: Blood
Blood (2015) 126 (23): 982.
https://doi.org/10.1182/blood.V126.23.982.982
Published: 2015
Journal Articles

A Phase I Trial Of Zileuton In Sickle Cell Disease

Marthe-Sandrine Eiymo Mwa Mpollo, M.Sc., Maa-Ohui Quarmyne, MBChB, Omar Rayes, MD, Caryn S. Gonsalves, PhD, Laurie Vanderah, RN, Christina Canter, Johnson Haynes, Jr., MD, Claudia Fernanda Clavijio, MD, Christians Uwe, MD, PhD, Karen Kalinyak, MD, Clinton H. Joiner, MD, PhD, Alexander A. Vinks, PharmD, PhD, FCP, Punam Malik, MD
Journal: Blood
Blood (2013) 122 (21): 993.
https://doi.org/10.1182/blood.V122.21.993.993
Published: 2013