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Journal Articles

CRISPR-Based Functional Genomics Studies Reveal Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins: Implications for Novel Therapeutics across Diverse Neoplasias

Ryosuke Shirasaki, MD PhD, Sara Gandolfi, MD, Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Dennis Buckley, Olga Dashevsky, PhD, Sondra L. Downey-Kopyscinski, PhD, Huihui Tang, PhD, Michal Sheffer, PhD, Eugen Dhimolea, PhD, Brian Glassner, PhD, Megan Bariteau, BSc, Jeffrey Sorrell, BA, Johanna B Bruggenthies, Quinlan Sievers, BA, Haley Poarch, Nicholas P Kwiatkowski, PhD, Tinghu Zhang, PhD, Jacob Laubach, MD, Robert L. Schlossman, MD, Paul Richardson, Aedin Culhane, PhD, Richard WJ Groen, PhD, Eric S. Fischer, PhD, Francisca Vazquez, PhD, Aviad Tsherniak, PhD, William C. Hahn, MD PhD, Joan Levy, Daniel Auclair, PhD, Jonathan D. Licht, MD, Jonathan J Keats, PhD, Lawrence H. Boise, PhD, Benjamin L. Ebert, MDPhD, James Bradner, MD, Nathanae Gray, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1367.
https://doi.org/10.1182/blood-2018-99-116232
Published: 2018
Journal Articles

MYD88 L265P Mutations Influence Clinical Outcome and Identify a Pathway for Targeted Inhibition in Chronic Lymphocytic Leukemia

Bethany Tesar, MS, Reina Improgo, PhD, Josephine L. Klitgaard, MSc,PhD, Reuma Magori-Cohen, Lijian Yu, Divya Chaudhary, Wenyan Miao, Stacey M. Fernandes, Kevin Hoang, William F Westlin, Haesook T. Kim, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2015) 126 (23): 491.
https://doi.org/10.1182/blood.V126.23.491.491
Published: 2015
Journal Articles

A Dynamic Intron Retention Program in the Mammalian Megakaryocyte and Erythrocyte Lineages

Christopher R Edwards, PhD, Rob Middleton, Xiuli An, MD PhD, Tejaswini Mishra, PhD, Narla Mohandas, DSc, Ross C. Hardison, PhD, John Rasko, MBBS, PhD, Gerd A. Blobel, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2380.
https://doi.org/10.1182/blood.V126.23.2380.2380
Published: 2015
Journal Articles

Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition

Michal Sheffer, PhD, Yiguo Hu, PhD, Ophir Shalem, PhD, Neville Sanjana, PhD, Eugen Dhimolea, PhD, Subhashis Sarkar, PhD, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Richard W.J. Groen, PhD, Feng Zhang, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 273.
https://doi.org/10.1182/blood.V124.21.273.273
Published: 2014
Journal Articles

CEBPα Is a Transcriptional Repressor of T-Cell Related Genes Explaining the Myeloid/T-Lymphoid Features of CEBPα-Silenced AML

Erdogan Taskesen, Roberto Avellino, Meritxell AlberichJorda, Daniel G. Tenen, Jeroen Ridder de, Peter Valk, Bas Wouters, Claudia Erpelinck, Marcel Reinders, Ruud Delwel, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 554.
https://doi.org/10.1182/blood.V118.21.554.554
Published: 2011
Journal Articles

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes

Gabriela B. Iwanski, MD, Nils H. Thoennissen, MD, Joy Nakitandwe, BSc, MSc, PhD, Patricia Lin, Norihiko Kawamata, Rahul Nahar, Parham Ramezani-Rad, Shann-Ching Chen, Sheila Shurtleff, PhD, Daniel Nowak, MD, Christian Ruckert, Martin Dugas, MD, Carsten Bokemeyer, MD, Grazia Fazio, Andrea Biondi, Professor, MD, Giovanni Cazzaniga, PhD, James R. Downing, MD, Markus Müschen, H. Phillip Koeffler, MD
Journal: Blood
Blood (2010) 116 (21): 3231.
https://doi.org/10.1182/blood.V116.21.3231.3231
Published: 2010
Journal Articles

Comparative gene expression analysis of zebrafish and mammals identifies common regulators in hematopoietic stem cells

e-blood
Isao Kobayashi, Hiromasa Ono, Tadaaki Moritomo, Koichiro Kano, Teruyuki Nakanishi, Toshio Suda
Journal: Blood
Blood (2010) 115 (2): e1–e9.
https://doi.org/10.1182/blood-2009-07-232322
Published: 2010
Includes: Supplemental data
Journal Articles

ABC and GCB DLBCLs Display Unique Biologically Distinct and Clinically Relevant Epigenetic Signatures.

Rita Shaknovich, MD/PhD, Huimin Geng, Ph.D., Nathalie Johnson, MD, Leandro Cerchietti, MD, Maria E Figueroa, MD, Lucas Tsikitas, Olivier Elemento, Ph.D., Joseph M. Connors, MD, Laurie Sehn, MD, MPH, Randy D. Gascoyne, MD, Ari Melnick, MD
Journal: Blood
Blood (2009) 114 (22): 619.
https://doi.org/10.1182/blood.V114.22.619.619
Published: 2009
Journal Articles

Redundant Leukemogenicity of NUP98-HOX Fusion Genes in Primary Murine Bone Marrow Cells Correlates with Gene Expression Changes Consistent with Common Key Target Genes.

Lars Palmqvist, MD, PhD, Nicolas Pineault, PhD, Patricia Rosten, Keith R. Humphries, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1134.
https://doi.org/10.1182/blood.V104.11.1134.1134
Published: 2004