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Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, Boaz Nachmias, MD PhD, Jordan M Chin, Fieke W Hoff, BSc, Kerstin Kaufmann, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Neil MacLean, Xiaoming Wang, Veronique Voisin, PhD, Aaron Botham, Andrea Arruda, Mark D. Minden, MD PhD, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD, Aaron D Schimmer, MD PhD

Blood (2019) 134 (Supplement_1): 2532.

https://doi.org/10.1182/blood-2019-123121

Published: 2019

Journal Articles

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Blood (2018) 132 (Supplement 1): 2543.

https://doi.org/10.1182/blood-2018-99-119262

Published: 2018

Journal Articles

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

Kristina Seiler, MD, Petra Minder, PhD, Iris Mashimo, Magali Humbert, PhD, Elizabeth Simpson, Mario P. Tschan, PhD, Bruce E. Torbett, PhD

Blood (2018) 132 (Supplement 1): 5088.

https://doi.org/10.1182/blood-2018-99-112145

Published: 2018

Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Thomas, PhD MSc, BSc, Laura Garcia Prat, Marcela Gronda, MSc, Rose Hurren, BSc, Neil MacLean, Xiaoming Wang, Botham Aaron, John E. Dick, Aaron D Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): 2795.

https://doi.org/10.1182/blood-2018-99-110021

Published: 2018

Journal Articles

Rasburicase and Glucose 6-Phophaste Dehydrogenase: Clinical Utility in the Management of Acute Leukemia Related Hyperuricemia

Walid Mohamedali, MD, Jesus Vera Aguilera, MD, Ryan M. Carr, MD, PhD, Mythri Mudireddy, MBBS, Abhishek Mangaonkar, MD, Jonas Paludo, MD, Kebede H. Begna, MD

Blood (2017) 130 (Supplement 1): 5668.

https://doi.org/10.1182/blood.V130.Suppl_1.5668.5668

Published: 2017

Journal Articles

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Zuzana Maceckova, MSc, Pavla Koralkova, MSc, Jana Volejnikova, MD PhD, Petr Vojta, MSc, Alexandra Jungova, MD, Zuzana Saxova, MSc, Renata Mojzikova, MSc, PhD, Marie Jarosova, MSc PhD, Ivana Hadacova, MD, Marian Hajduch, MD PhD, Monika Horvathova, MSc, PhD, Dagmar Pospisilova, MD PhD

Blood (2016) 128 (22): 3903.

https://doi.org/10.1182/blood.V128.22.3903.3903

Published: 2016

Journal Articles

Incidence of Hemolytic Events after Exposure to Triggering Medications in Pediatric Patients with G6PD Deficiency

Bhavya Doshi, MD, Aditi Kamdar, MD, Kim Smith-Whitley, MD, Michele P Lambert, MD MTR, Amrom Obstfeld, MD PhD

Blood (2016) 128 (22): 4810.

https://doi.org/10.1182/blood.V128.22.4810.4810

Published: 2016

Journal Articles

Characteristics and Outcome of Direct Antiglobulin Test-Negative Hemolytic Anemia: A Case Series

Aishwarya Ravindran, MBBS, Janani Sankaran, MBBS, Min Shi, MD PhD, Eapen K. Jacob, MD, Justin D. Kreuter, MD, Jeffrey L. Winters, MD, C. Christopher Hook, MD, Timothy G. Call, MD, Ariela L. Marshall, MD, Rajiv K. Pruthi, MD, Aneel A. Ashrani, MD MS, Kebede H. Begna, MD, Neil E. Kay, MD, Ronald S. Go, MD

Blood (2016) 128 (22): 2451.

https://doi.org/10.1182/blood.V128.22.2451.2451

Published: 2016

Journal Articles

Cap Analysis of Gene Expression (CAGE) Sequencing Reveals Alterations of the Transcript Signatures in Acute Monocytic Leukemia Cells By Fatty Acid Oxidation Inhibition

Yoko Tabe, MD PhD, Marina Konopleva, MD PhD, Norikazu Monma, PhD, Kazuho Ikeo, PhD, Kaoru Mogushi, PhD, Yasunari Yamanaka, MD PhD, Hiromichi Matsushita, MD PhD, Takashi Miida, MD PhD, Yoshihide Hayashizaki, MD PhD, Michael Andreeff, MD PhD

Blood (2015) 126 (23): 3631.

https://doi.org/10.1182/blood.V126.23.3631.3631

Published: 2015

Journal Articles

Novel FAO Inhibitor Avocatin B Induces Apoptosis of Acute Monocytic Leukemia Cells in Adipocyte Co-Culture System Via ER Stress and ATF4 Activation

Yoko Tabe, MD PhD, Shinichi Yamamoto, PhD, Mika Kikkawa, PhD, Hikari Taka, PhD, Kaoru Mogushi, PhD, Hiromichi Mastushita, MD PhD, Takashi Miida, MDPhD, Michael Andreeff, MD PhD, Paul A Spagnuolo, PhD, Marina Konopleva, MD PhD

Blood (2015) 126 (23): 3692.

https://doi.org/10.1182/blood.V126.23.3692.3692

Published: 2015

Journal Articles

Mesenchymal Stem Cells Lacking Glucose-6-Phosphatase-β Exhibit Disturbed Energy Homeostasis and Defective Adipogenesis

Hyun Sik Jun, PhD, Janice Y Chou, PhD

Blood (2014) 124 (21): 4323.

https://doi.org/10.1182/blood.V124.21.4323.4323

Published: 2014

Journal Articles

Up-Regulation of Hexokinase II (HK) Alters the Glucose Metabolism and Disrupts the Mitochondrial Potential in Aggressive B-Cell Lymphoma Contributing to Rituximab-Chemotherapy Resistance and Is a Clinically Relevant Target for Future Therapeutic Development

Juan J Gu, PhD, Anil Singh, MD, Cory Mavis, MSc, Vivek Yanamadala, Kai Xue, MD, Michael Grau, Peter Lenz, Georg Lenz, Myron S. Czuczman, MD, Francisco Hernandez, MD

Blood (2014) 124 (21): 1767.

https://doi.org/10.1182/blood.V124.21.1767.1767

Published: 2014

Journal Articles

Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death

Li Yin, Turner Kufe, David Avigan, Donald Kufe

Blood (2014) 123 (19): 2997–3006.

https://doi.org/10.1182/blood-2013-11-539395

Published: 2014

Includes: Supplemental data

Journal Articles

Neutropenia In Glycogen Storage Disease 1b (GSD1b)

David C. Dale, MD, Audrey Anna Bolyard, RN, BS, Tracy M. Marrero, Merideth L. Kelley, MS, BS, Lan Phan, BA, Laurence A. Boxer, MD, Priya S. Kishnani, MD, MB, Joanne Kurtzberg, MD, David A. Weinstein, MD, MMSc

Blood (2013) 122 (21): 2265.

https://doi.org/10.1182/blood.V122.21.2265.2265

Published: 2013

Journal Articles

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance In Multiple Myeloma

Patricia Maiso, PhD, Daisy Huynh, MPS, Yosra Aljawai, MS, John M. Asara, PhD, Antonio Sacco, BS, Michele Moschetta, MD, Yuji Mishima, PhD, Aldo M Roccaro, MD, PhD, Alec Kimmelman, MD, PhD, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 121.

https://doi.org/10.1182/blood.V122.21.121.121

Published: 2013

Journal Articles

Glucose Phosphate Isomerase Deficiency In 2 Patients With Novel Mutations Presenting As Severe Neurologic Abnormalities and Transfusion Dependent Hemolytic Anemia

Mammen Puliyel, M.B., B.S., Patrick G. Gallagher, MD, Vasilios Berdoukas, MBBS, Bertil Glader, MD, PhD, Thomas Coates, MD

Blood (2013) 122 (21): 947.

https://doi.org/10.1182/blood.V122.21.947.947

Published: 2013

Journal Articles

Novel Haemoglobin Variant [β42 Phe → Cys]: Hb Little Venice

Jack Bartram, MBBCh, MRCPCH, John Old, PhD, Lorry Phelan, Mark Layton, MD, Josu de la Fuente, PhD, FRCP, MRCPCH, FRCPath

Blood (2012) 120 (21): 1013.

https://doi.org/10.1182/blood.V120.21.1013.1013

Published: 2012

Journal Articles

SCT for Secondary AML in a Patient with Glycogen Storage Disease Type 1b

Cornelia Zeidler, MD, Kinan Kafa, Martin G. Sauer, MD, Britta Maecker-Kolhoff, Johann Greil, MD, Karl Welte, MD, Christian P Kratz, MD, Karl-Walter Sykora

Blood (2012) 120 (21): 4402.

https://doi.org/10.1182/blood.V120.21.4402.4402

Published: 2012

Journal Articles

BCR-ABL Transformation Requires Glycogen Synthase 1 (GYS1) Expression for Cell Growth and Increased Glycogen Production

Mamatha M. Reddy, PhD, Anagha Deshpande, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Tirumala K. Chowdary, PhD, James D. Griffin, MD, Martin Sattler, PhD

Blood (2012) 120 (21): 1673.

https://doi.org/10.1182/blood.V120.21.1673.1673

Published: 2012

Journal Articles

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase–deficient children receiving dapsone

Allan Pamba, Naomi D. Richardson, Nick Carter, Stephan Duparc, Zul Premji, Alfred B. Tiono, Lucio Luzzatto

Blood (2012) 120 (20): 4123–4133.

https://doi.org/10.1182/blood-2012-03-416032

Published: 2012

Includes: Supplemental data

NARROW

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Rasburicase and Glucose 6-Phophaste Dehydrogenase: Clinical Utility in the Management of Acute Leukemia Related Hyperuricemia

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Incidence of Hemolytic Events after Exposure to Triggering Medications in Pediatric Patients with G6PD Deficiency

Characteristics and Outcome of Direct Antiglobulin Test-Negative Hemolytic Anemia: A Case Series

Cap Analysis of Gene Expression (CAGE) Sequencing Reveals Alterations of the Transcript Signatures in Acute Monocytic Leukemia Cells By Fatty Acid Oxidation Inhibition

Novel FAO Inhibitor Avocatin B Induces Apoptosis of Acute Monocytic Leukemia Cells in Adipocyte Co-Culture System Via ER Stress and ATF4 Activation

Mesenchymal Stem Cells Lacking Glucose-6-Phosphatase-β Exhibit Disturbed Energy Homeostasis and Defective Adipogenesis

Up-Regulation of Hexokinase II (HK) Alters the Glucose Metabolism and Disrupts the Mitochondrial Potential in Aggressive B-Cell Lymphoma Contributing to Rituximab-Chemotherapy Resistance and Is a Clinically Relevant Target for Future Therapeutic Development

Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death

Neutropenia In Glycogen Storage Disease 1b (GSD1b)

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance In Multiple Myeloma

Glucose Phosphate Isomerase Deficiency In 2 Patients With Novel Mutations Presenting As Severe Neurologic Abnormalities and Transfusion Dependent Hemolytic Anemia

Novel Haemoglobin Variant [β42 Phe → Cys]: Hb Little Venice

SCT for Secondary AML in a Patient with Glycogen Storage Disease Type 1b

BCR-ABL Transformation Requires Glycogen Synthase 1 (GYS1) Expression for Cell Growth and Increased Glycogen Production

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase–deficient children receiving dapsone

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American Society of Hematology

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American Society of Hematology

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