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Journal Articles

Control of hemolysis in patients with PNH

Lucio Luzzatto

Blood (2021) 138 (20): 1908–1910.

https://doi.org/10.1182/blood.2021013169

Published: 2021

Journal Articles

Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH

Michela Sica, Annamaria Pellecchia, Maria De Angioletti, Giovanni Caocci, Caterina Nannelli, Giorgio La Nasa, Lucio Luzzatto, Rosario Notaro

Blood (2020) 136 (26): 3082–3085.

https://doi.org/10.1182/blood.2020007780

Published: 2020

Includes: Supplemental data

Journal Articles

Glucose-6-phosphate dehydrogenase deficiency

Lucio Luzzatto, Mwashungi Ally, Rosario Notaro

Blood (2020) 136 (11): 1225–1240.

https://doi.org/10.1182/blood.2019000944

Published: 2020

Includes: Supplemental data

Journal Articles

Two Distinct but Functionally Related Autoreactive T Cell Populations in Paroxysmal Nocturnal Hemoglobinuria and Idiopathic Aplastic Anemia: Glycosylphosphatidylinositol-Specific and IFNγ-Producing T Cells

Lucia Gargiulo, PhD, Michela Sica, PhD, Caterina Nannelli, BSc, Lucio Luzzatto, MD, Rosario Notaro, MD

Blood (2017) 130 (Supplement 1): 1166.

https://doi.org/10.1182/blood.V130.Suppl_1.1166.1166

Published: 2017

Journal Articles

Splenomegaly in Adolescents and Adults with Sickle Cell Anemia in Tanzania Is Associated with Less Severe Disease

Neema Budodi Lubuva, MD MMed, Venee N. Tubman, MD MMSc, Clara C Chamba, MD MMed, Erius Tebuka, MD MMed, Mbonea Yonazi, MD MMed, Furahini Tluway, MD MPH, Pius Magesa, MD MPath, Lucio Luzzatto, MD, Julie Makani, MD PhD FRCP, Magdalena Lyimo, MD PhD

Blood (2017) 130 (Supplement 1): 4793.

https://doi.org/10.1182/blood.V130.Suppl_1.4793.4793

Published: 2017

Journal Articles

Glycosylphosphatidylinositol-specific T cells, IFN-γ-producing T cells, and pathogenesis of idiopathic aplastic anemia

Lucia Gargiulo, Yoshitaka Zaimoku, Barbara Scappini, Hiroyuki Maruyama, Rie Ohumi, Lucio Luzzatto, Shinji Nakao, Rosario Notaro

Blood (2017) 129 (3): 388–392.

https://doi.org/10.1182/blood-2016-09-740845

Published: 2017

Journal Articles

Auto-Reactive Glycosyl-Phosphatidyl-Inositol (GPI) Specific T Cells Are Present in Most Patients with Idiopathic Aplastic Anemia (IAA)

Lucia Gargiulo, PhD, Yoshitaka Zaimoku, MD, Barbara Scappini, MD, Hiroyuki Maruyama, MD, Rie Ohumi, Lucio Luzzatto, MD, Shinji Nakao, MD PhD, Rosario Notaro, MD

Blood (2015) 126 (23): 2409.

https://doi.org/10.1182/blood.V126.23.2409.2409

Published: 2015

Journal Articles

Complement Activation in Paroxysmal Nocturnal Hemoglobinuria (PNH) Causes Oxidative Damage Which May Affect Response to Eculizumab

Michela Sica, PhD, Annamaria Pellecchia, PhD, Margherita Berardi, BS, Lucia Gargiulo, PhD, Tolulase A Olutogun, MD, Giovanni Caocci, MD, Giorgio La Nasa, MD, Maria De Angioletti, PhD, Lucio Luzzatto, MD FRCP, FRCPath, Rosario Notaro, MD

Blood (2014) 124 (21): 4397.

https://doi.org/10.1182/blood.V124.21.4397.4397

Published: 2014

Journal Articles

Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells

Kalliopi Makarona, Valentina S. Caputo, Joana R. Costa, Binbin Liu, David O’Connor, Deena Iskander, David Roper, Lynn Robertson, Neha Bhatnagar, Evangelos Terpos, Elisabeth Georgiou, Maria Papaioannou, D. Mark Layton, Lucio Luzzatto, Irene Roberts, Anastasios Karadimitris

Blood (2014) 124 (1): 134–141.

https://doi.org/10.1182/blood-2014-02-553792

Published: 2014

Includes: Supplemental data

Journal Articles

PNH from mutations of another PIG gene

Lucio Luzzatto

Blood (2013) 122 (7): 1099–1100.

https://doi.org/10.1182/blood-2013-06-508556

Published: 2013

Journal Articles

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria

Lucia Gargiulo, Maria Papaioannou, Michela Sica, Giulia Talini, Aristeidis Chaidos, Barbara Richichi, Andrei V. Nikolaev, Cristina Nativi, Mark Layton, Josu de la Fuente, Irene Roberts, Lucio Luzzatto, Rosario Notaro, Anastasios Karadimitris

Blood (2013) 121 (14): 2753–2761.

https://doi.org/10.1182/blood-2012-11-469353

Published: 2013

Includes: Supplemental data

Journal Articles

Autoreactive T Cells From Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Specifically Recognize Glycosyl- Phosphatidyl-Inositol (GPI)

Lucia Gargiulo, PhD, Michela Sica, PhD, Maria Papaioannou, MD, PhD, Giulia Talini, PhD, Aristeidis Chaidos, MD, PhD, Barbara Richichi, PhD, Andrei V Nikolaev, PhD, Cristina Nativi, PhD, Mark Layton, MD, Josu de la Fuente, MRCP, MRCPCH, FRCPath, Irene Roberts, Lucio Luzzatto, MD, FRCP, FRCPath, Rosario Notaro, MD, Anastasios Karadimitris, MD, PhD

Blood (2012) 120 (21): 647.

https://doi.org/10.1182/blood.V120.21.647.647

Published: 2012

Journal Articles

Genetic Polymorphism of the Complement Receptor-1 ( CR1 ) Gene Correlates with the Clinical Response to Eculizumab of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Tommaso Rondelli, BS, Antonio M. Risitano, MD, PhD, Régis Peffault de Latour, MD, Benedetta Peruzzi, PhD, Ricci Patrizia, BS, Wilma Barcellini, MD, Anna Paola Iori, Carla Boschetti, MD, Veronica Valle, MD, Veronique Frémeaux-Bacchi, PhD, Maria De Angioletti, PhD, Gerard Socie, Lucio Luzzatto, MD, FRCP, FRCPath, Rosario Notaro, MD

Blood (2012) 120 (21): 983.

https://doi.org/10.1182/blood.V120.21.983.983

Published: 2012

Journal Articles

Selective Splenic Artery Embolization for the Treatment of Thrombocytopenia and Hypersplenism in Paroxysmal Nocturnal Hemoglobinuria (PNH)

Anna Paola Iori, Karen Brown, David J. Araten, Emilia Scalzulli, Giovanni Fernando Torelli, Maria Stefania De Propris, Corrado Girmenia, Filippo Maria Salvatori, Orly Zelig, Robin Foa, MD, Lucio Luzzatto

Blood (2012) 120 (21): 4408.

https://doi.org/10.1182/blood.V120.21.4408.4408

Published: 2012

Journal Articles

Role of the Somatic Mutation Rate in Patients with Classical Myeloproliferative Neoplasms (MPN) with and without Other Neoplasms

Margherita Berardi, BS, Tommaso Rondelli, BS, Maria Chiara Susini, MD, Annamaria Pellecchia, BS, Elisabetta Antonioli, MD, Luca Boni, MD, Lucio Luzzatto, MD, FRCP, FRCPath, Alessandro M. Vannucchi, MD, Rosario Notaro, MD

Blood (2012) 120 (21): 5055.

https://doi.org/10.1182/blood.V120.21.5055.5055

Published: 2012

Journal Articles

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase–deficient children receiving dapsone

Allan Pamba, Naomi D. Richardson, Nick Carter, Stephan Duparc, Zul Premji, Alfred B. Tiono, Lucio Luzzatto

Blood (2012) 120 (20): 4123–4133.

https://doi.org/10.1182/blood-2012-03-416032

Published: 2012

Includes: Supplemental data

Journal Articles

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment opsonization

Antonio M. Risitano, Rosario Notaro, Caterina Pascariello, Michela Sica, Luigi del Vecchio, Christopher J. Horvath, Masha Fridkis-Hareli, Carmine Selleri, Margaret A. Lindorfer, Ronald P. Taylor, Lucio Luzzatto, V. Michael Holers

Blood (2012) 119 (26): 6307–6316.

https://doi.org/10.1182/blood-2011-12-398792

Published: 2012

Includes: Supplemental data

Journal Articles

Long Term Safety and Efficacy of Sustained Eculizumab Treatment In Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Robert A Brodsky, MD, Carlos de Castro, III, MD, Hubert Schrezenmeier, MD, Professor, Antonio M. Risitano, MD, PhD, Joerg Schubert, MD, Jaroslaw P Maciejewski, MD, PhD, FACP, Ulrich Duehrsen, MD, Lucio Luzzatto, MD, FRCP, FRCPath, Petra Muus, MD, PhD, Jeffrey Szer, BMedSc, MBBS, FRACP, Gérard Socié, MD, PhD, Peter Hillmen, MBChB, FRCP, FRCPath, PhD

Blood (2010) 116 (21): 4237.

https://doi.org/10.1182/blood.V116.21.4237.4237

Published: 2010

Journal Articles

Thrombolytic Therapy for Reversal of Thrombosis In Paroxysmal Nocturnal Hemoglobinuria (PNH)

David J Araten, MD, Rosario Notaro, MD, Nancy A Kernan, MD, Farid Boulad, MD, Hugo Castro-Malaspina, MD, Trudy N Small, M.D, Andromachi Scaradavou, MD, Heather Magnan, MD, Susan E Prockop, MD, Sara Chaffee, MD, Jason Gonsky, MD, PhD, Raymond Thertulien, MD, PhD, Roberto Tarquini, MD, Lucio Luzzatto, MD

Blood (2010) 116 (21): 4239.

https://doi.org/10.1182/blood.V116.21.4239.4239

Published: 2010

Journal Articles

Effects of Eculizumab Therapy in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Receiving Concurrent Immunosuppressive Therapy for Bone Marrow Insufficiency.

Hubert Schrezenmeier, Joerg Schubert, MD, Lucio Luzzatto, MD, Petra Muus, MD, PhD, Gerard Socie, MD, PhD, Antonio M. Risitano, MD, PhD, Anita Hill, MBChB, (Hons), PhD, Peter Hillmen, MB, ChB, PhD

Blood (2009) 114 (22): 3012.

https://doi.org/10.1182/blood.V114.22.3012.3012

Published: 2009

NARROW

Control of hemolysis in patients with PNH

Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH

Glucose-6-phosphate dehydrogenase deficiency

Two Distinct but Functionally Related Autoreactive T Cell Populations in Paroxysmal Nocturnal Hemoglobinuria and Idiopathic Aplastic Anemia: Glycosylphosphatidylinositol-Specific and IFNγ-Producing T Cells

Splenomegaly in Adolescents and Adults with Sickle Cell Anemia in Tanzania Is Associated with Less Severe Disease

Glycosylphosphatidylinositol-specific T cells, IFN-γ-producing T cells, and pathogenesis of idiopathic aplastic anemia

Auto-Reactive Glycosyl-Phosphatidyl-Inositol (GPI) Specific T Cells Are Present in Most Patients with Idiopathic Aplastic Anemia (IAA)

Complement Activation in Paroxysmal Nocturnal Hemoglobinuria (PNH) Causes Oxidative Damage Which May Affect Response to Eculizumab

Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells

PNH from mutations of another PIG gene

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria

Autoreactive T Cells From Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Specifically Recognize Glycosyl- Phosphatidyl-Inositol (GPI)

Genetic Polymorphism of the Complement Receptor-1 ( CR1 ) Gene Correlates with the Clinical Response to Eculizumab of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Selective Splenic Artery Embolization for the Treatment of Thrombocytopenia and Hypersplenism in Paroxysmal Nocturnal Hemoglobinuria (PNH)

Role of the Somatic Mutation Rate in Patients with Classical Myeloproliferative Neoplasms (MPN) with and without Other Neoplasms

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase–deficient children receiving dapsone

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment opsonization

Long Term Safety and Efficacy of Sustained Eculizumab Treatment In Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Thrombolytic Therapy for Reversal of Thrombosis In Paroxysmal Nocturnal Hemoglobinuria (PNH)

Effects of Eculizumab Therapy in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Receiving Concurrent Immunosuppressive Therapy for Bone Marrow Insufficiency.

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American Society of Hematology

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American Society of Hematology

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