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Journal Articles

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

So Hyun Park, BS, Ciaran M Lee, PhD, Yankai Zhang, PhD, Alicia Chang, MD, Vivien A Sheehan, MD PhD, Gang Bao, PhD

Blood (2018) 132 (Supplement 1): 3478.

https://doi.org/10.1182/blood-2018-99-114241

Published: 2018

Journal Articles

Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders

Christina Caruso, MD, Puneeth Guruprasad, Robert G Mannino, PhD, Hanqing Zhang, PhD, Cassandra D Josephson, MD, John D Roback, MD PhD, Wilbur A Lam, MD PhD

Blood (2018) 132 (Supplement 1): 1033.

https://doi.org/10.1182/blood-2018-99-118830

Published: 2018

Journal Articles

Sickle Human Umbilical Cord Derived Erythroid Progenitor Cells (S-HUDEP2): An Ideal in-Vitro System for Screening Anti-Sickling Compounds for Sickle Cell Disease

Alicia Chang, MD, So Hyun Park, BS, Ciaran M Lee, PhD, Alireza Paikari, MD, Gang Bao, PhD, Vivien A Sheehan, MD PhD

Blood (2018) 132 (Supplement 1): 3675.

https://doi.org/10.1182/blood-2018-99-117158

Published: 2018

Journal Articles

SCD-101: A New Anti-Sickling Drug Reduces Pain and Fatigue and Improves Red Blood Cell Shape in Peripheral Blood of Patients with Sickle Cell Disease

Robert Swift, PhD, Osheiza Abdulmalik, DVM, MS, Qiukan Chen, Toshio Asakura, MD PhD, Kelsey Gustafson, MS, James E Simon, PhD, Virdah Zaman, MS, Kevin Alexis Quiusky, MD, Kathryn L. Hassell, MD, Iuliana Shapira, MD, Gurinder Sidhu, MD, Tracian James-Goulbourne, MD, Kisha Carrington, MD, John Muthu, MD, Peter N Gillette, MD

Blood (2016) 128 (22): 121.

https://doi.org/10.1182/blood.V128.22.121.121

Published: 2016

Journal Articles

Vzhe-039, a Novel Structurally-Enhanced Allosteric Hemoglobin Effector Inhibits Sickling of SS Erythrocytes In Vitro , and Exhibits Improved Pharmacologic Properties In Vivo

Martin K. Safo, PhD, Guoyan Xu, PhD, Mohini Ghatge, PhD, Qiukan Chen, Carla Casu, PhD, David Tanya, PhD, Yan Zhang, PhD, Jurgen Venitz, MD PhD, Osheiza Abdulmalik, DVM, MS

Blood (2016) 128 (22): 3645.

https://doi.org/10.1182/blood.V128.22.3645.3645

Published: 2016

Journal Articles

Erythrocyte Rigidity Affects Blood Clot Contraction and Formation of Polyhedrocytes

Valerie Tutwiler, Rustem I. Litvinov, PhD, Chandrasekaran Nagaswami, J. Eric Russell, MD, Don L. Siegel, MD, PhD,, Carlos Hipolito Villa, MD PhD, Daniel Pan, PhD, Vladimir R Muzykantov, MD PhD, John W. Weisel

Blood (2016) 128 (22): 3814.

https://doi.org/10.1182/blood.V128.22.3814.3814

Published: 2016

Journal Articles

Clot Contraction-Mediated Erythrocyte Packing Is Significantly Altered in Sickle Cell Disease

Hunter Strauss, David R Myers, PhD, Margo Renee Rollins, MD, John W. Weisel, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 215.

https://doi.org/10.1182/blood.V126.23.215.215

Published: 2015

Journal Articles

GTx011, a Potent Allosteric Modifier of Hemoglobin Oxygen Affinity, Prevents RBC Sickling in Whole Blood and Prolongs RBC Half-Life in Vivo in a Murine Model of Sickle Cell Disease

Kobina Dufu, PhD, Donna Oksenberg, PhD, Chengjing Zhou, Athiwat Hutchaleelaha, PhD, David R. Archer, PhD

Blood (2014) 124 (21): 217.

https://doi.org/10.1182/blood.V124.21.217.217

Published: 2014

Journal Articles

Rapid Reversal of Red Blood Cell Sickling Promoted By Pegylated Carboxyhemoglobin Bovine Gas Transfer Properties

Ronald Jubin, PhD, Peter Buontempo, MSc, BSc, Ricardo A Yglesias, BA, MS, Abe Abuchowski, PhD MHS, Yuli Chen, BS, MS, Glenn Kazo, MS, Friedericke Kazo, MS

Blood (2014) 124 (21): 1372.

https://doi.org/10.1182/blood.V124.21.1372.1372

Published: 2014

Journal Articles

The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro

Laurel G. Mendelsohn, B.S., Leah Pedoeim, B.S., Yekai Kevin Wang, B.S., Rehan Saiyed, B.S., Christine A. Brantner, PhD, Mathew P. Daniels, PhD, James S. Nichols, RN, Xunde Wang, Ph.D., Eduard J. van Beers, MD, PhD, Gregory J. Kato, M.D.

Blood (2013) 122 (21): 940.

https://doi.org/10.1182/blood.V122.21.940.940

Published: 2013

Journal Articles

In Vitro Stromal Co-Culture Model For The Evaluation Of Reovirus Oncolytic Therapy For Refractory Pediatric Leukemia

Gaya Narendran, Matthew F. Clarkson, Randal Johnston, PhD

Blood (2013) 122 (21): 5407.

https://doi.org/10.1182/blood.V122.21.5407.5407

Published: 2013

Journal Articles

The First Report Of Differences In Fibrin Clot Nanostructure and Response To Tissue Plasminogen Activator (TPA) and Unfractionated Heparin (UFH) In Infants Compared To Adults

Vera Ignjatovic, PhD, Leonie Pelkmans, Saartje Bloemen, Vasiliki Karlaftis, Chantal Attard, Raed Al Dieri, PhD, Bas de Laat, PhD, Paul Monagle, MBBS, MD, MSc

Blood (2013) 122 (21): 459.

https://doi.org/10.1182/blood.V122.21.459.459

Published: 2013

Journal Articles

The Architecture Of Fibrin Clots Formed From Plasma With Low Platelet Levels Are Less Altered In The Presence Of Factor-Specific Anticoagulants Compared With Unfractionated Heparin

Jorell Gantioqui, MSc candidate, Ivan Stevic, PhD, Paul Y. Kim, PhD, Keith K. Lau, MBBS, FRCP(C), FRCP(Lond), Anthony K.C. Chan, MBBS, FRCPC, FRCPath, Howard H.W. Chan, MBChB, FRCPC, MSc, FRCP(Glasg), FRCP(Ireland)

Blood (2013) 122 (21): 578.

https://doi.org/10.1182/blood.V122.21.578.578

Published: 2013

Journal Articles

How Does CD47-SIRPα ‘Don’t Eat Me Signal’ Physically Signal Self

Sosale Nisha, Dennis E. Discher, Ph.D.

Blood (2013) 122 (21): 953.

https://doi.org/10.1182/blood.V122.21.953.953

Published: 2013

Journal Articles

Imaging Flow Cytometry for Fully Automated Quantification of Percentage of Sickled Cells in Sickle Cell Anemia.

Eduard J. van Beers, MD, PhD, Leigh Samsel, MS, Laurel G. Mendelsohn, M.S., Rehan Saiyed, BS, James S Nichols, RN, J. Philip McCoy, Jr., PhD, Gregory J. Kato, M.D.

Blood (2012) 120 (21): 2105.

https://doi.org/10.1182/blood.V120.21.2105.2105

Published: 2012

Journal Articles

Increased Erythrocyte Rigidity Is Sufficient to Cause Endothelial Dysfunction in Sickle Cell Disease

Robert Mannino, David R Myers, PhD, Yumiko Sakurai, MSc, Russell E. Ware, MD, PhD, Gilda Barabino, PhD, Wilbur Lam, MD, PhD

Blood (2012) 120 (21): 818.

https://doi.org/10.1182/blood.V120.21.818.818

Published: 2012

Journal Articles

Antigen-Specific Transfer of Functional Programmed Death Ligand 1 From Antigen Presenting Cells Onto Human CD8 + T Cells Via Trogocytosis

Regina Gary, Simon Voelkl, PhD, Ralf Palmisano, PhD, Andreas Mackensen, MD

Blood (2010) 116 (21): 584.

https://doi.org/10.1182/blood.V116.21.584.584

Published: 2010

Journal Articles

Shape Recovery of Human Crenated Erythrocyte Ghosts Depends on the Cytoplasmic Endoskeletal Actin Filaments

Kazutaka Terasawa, MD, PhD, Takehito Taguchi, MD, PhD, Ryusuke Momota, PhD, Ichiro Naito, PhD, Aiji Ohtsuka, MD, PhD

Blood (2008) 112 (11): 5383.

https://doi.org/10.1182/blood.V112.11.5383.5383

Published: 2008

Journal Articles

Therapeutic Lymphoma Idiotype Vaccine Generated in Insect Cells Results in Mannose Receptor Targeting and Enhanced Immune Activation.

David J. Betting, MS, Xi Y. Mu, PhD, Kamran Kafi, B.S., Desmond McDonnel, Francisco Rosas, Daniel P. Gold, PhD, John M. Timmerman, M.D.

Blood (2007) 110 (11): 2343.

https://doi.org/10.1182/blood.V110.11.2343.2343

Published: 2007

Journal Articles

Reduced Oxidative Stress and Enhanced Nitric Oxide (NO) Bioavailability in Transgenic-Knockout Sickle Mice Expressing Fetal Hemoglobin (HbF) Is Mediated by Decreased Sickling and Hemolysis.

Trisha Dasgupta, Ph.D., Mary E. Fabry, Ph.D., Dhananjay K. Kaul, PhD

Blood (2007) 110 (11): 842.

https://doi.org/10.1182/blood.V110.11.842.842

Published: 2007

NARROW

Engineered Human Umbilical Cord Derived Erythroid Progenitor Cells (HUDEP2) with Sickle or β-Thalassemia Mutation: An in-Vitro System for Testing Pharmacological Induction of Fetal Hemoglobin

Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders

Sickle Human Umbilical Cord Derived Erythroid Progenitor Cells (S-HUDEP2): An Ideal in-Vitro System for Screening Anti-Sickling Compounds for Sickle Cell Disease

SCD-101: A New Anti-Sickling Drug Reduces Pain and Fatigue and Improves Red Blood Cell Shape in Peripheral Blood of Patients with Sickle Cell Disease

Vzhe-039, a Novel Structurally-Enhanced Allosteric Hemoglobin Effector Inhibits Sickling of SS Erythrocytes In Vitro , and Exhibits Improved Pharmacologic Properties In Vivo

Erythrocyte Rigidity Affects Blood Clot Contraction and Formation of Polyhedrocytes

Clot Contraction-Mediated Erythrocyte Packing Is Significantly Altered in Sickle Cell Disease

GTx011, a Potent Allosteric Modifier of Hemoglobin Oxygen Affinity, Prevents RBC Sickling in Whole Blood and Prolongs RBC Half-Life in Vivo in a Murine Model of Sickle Cell Disease

Rapid Reversal of Red Blood Cell Sickling Promoted By Pegylated Carboxyhemoglobin Bovine Gas Transfer Properties

The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro

In Vitro Stromal Co-Culture Model For The Evaluation Of Reovirus Oncolytic Therapy For Refractory Pediatric Leukemia

The First Report Of Differences In Fibrin Clot Nanostructure and Response To Tissue Plasminogen Activator (TPA) and Unfractionated Heparin (UFH) In Infants Compared To Adults

The Architecture Of Fibrin Clots Formed From Plasma With Low Platelet Levels Are Less Altered In The Presence Of Factor-Specific Anticoagulants Compared With Unfractionated Heparin

How Does CD47-SIRPα ‘Don’t Eat Me Signal’ Physically Signal Self

Imaging Flow Cytometry for Fully Automated Quantification of Percentage of Sickled Cells in Sickle Cell Anemia.

Increased Erythrocyte Rigidity Is Sufficient to Cause Endothelial Dysfunction in Sickle Cell Disease

Antigen-Specific Transfer of Functional Programmed Death Ligand 1 From Antigen Presenting Cells Onto Human CD8 + T Cells Via Trogocytosis

Shape Recovery of Human Crenated Erythrocyte Ghosts Depends on the Cytoplasmic Endoskeletal Actin Filaments

Therapeutic Lymphoma Idiotype Vaccine Generated in Insect Cells Results in Mannose Receptor Targeting and Enhanced Immune Activation.

Reduced Oxidative Stress and Enhanced Nitric Oxide (NO) Bioavailability in Transgenic-Knockout Sickle Mice Expressing Fetal Hemoglobin (HbF) Is Mediated by Decreased Sickling and Hemolysis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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