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Journal Articles

The Alternate Activation of Hedgehog Pathway, Either in CD138+ or in CD138-CD19+ Multiple Myeloma Primary Cells, Impacts on Disease Outcome

Marina Martello, PhD, Daniel Remondini, PhD, Enrica Borsi, PhD, Mauro Procacci, Barbara Santacroce, Annalisa Pezzi, PhD, Angela Flores Dico, Elena Zamagni, Paola Tacchetti, MD, Lucia Pantani, MD, Giulia Marzocchi, PhD, Giovanni Martinelli, MD PhD, Michele Cavo, Carolina Terragna, PhD
Journal: Blood
Blood (2015) 126 (23): 2961.
https://doi.org/10.1182/blood.V126.23.2961.2961
Published: 2015
Journal Articles

GLI1 Inhibitor GANT61 Deregulates stat3 Phosphorylation In Chronic Lymphocytic Leukemia Cells

Cheng Wang, Kang Lu MM, Xin Wang
Journal: Blood
Blood (2013) 122 (21): 4935.
https://doi.org/10.1182/blood.V122.21.4935.4935
Published: 2013
Journal Articles

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

Jasmin Wellbrock, Ph.D., Julian M Koehler, Katharina Wagner, MD, Emily Latuske, M.Sc., Hauke Stamm, M.Sc., Eik Vettorazzi, M.Sc., Gabi Vohwinkel, M.Sc., Marianne Klokow, Roswitha Kuhling-Thees, Sonja Loges, MD, Ph.D, Michael Amling, MD, Carsten Bokemeyer, MD, Michael Heuser, MD, Juergen Krauter, MD, Walter Fiedler, MD
Journal: Blood
Blood (2013) 122 (21): 53.
https://doi.org/10.1182/blood.V122.21.53.53
Published: 2013
Journal Articles

Hedgehog Ligands and Receptors Are Deregulated in Myelodysplastic Syndromes

Juliana M. Xavier, Amanda I Dias, Paulo Latuf-Filho, PhD, Fabiola Traina, MD, PhD, José Vassallo, MD.PhD., Sara T Olalla Saad, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3817.
https://doi.org/10.1182/blood.V120.21.3817.3817
Published: 2012
Journal Articles

Molecular Characterization of the Leukemic Niche in Chronic Myeloid Leukemia (CML) and Evaluation of a Leukemia / Niche Cross-Talk

Djamel Aggoune, Nathalie Sorel, PhD, Sanaa El Marsafy, MD, PhD, Marie Laure Bonnet, Denis Clay, Marie Claude Meunier, Karin Tarte, Olivier Herault, MD, PhD, Jorge Domenech, MD, PhD, Agnès Guerci, MD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, M.D., PhD
Journal: Blood
Blood (2012) 120 (21): 908.
https://doi.org/10.1182/blood.V120.21.908.908
Published: 2012
Journal Articles

Regulation of murine normal and stress-induced erythropoiesis by Desert Hedgehog

Ching-in Lau, Susan V. Outram, José Ignacio Saldaña, Anna L. Furmanski, Johannes T. Dessens, Tessa Crompton
Journal: Blood
Blood (2012) 119 (20): 4741–4751.
https://doi.org/10.1182/blood-2011-10-387266
Published: 2012
Journal Articles

Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL

Sarah Decker, Katja Zirlik, Lauritte Djebatchie, David Hartmann, Gabriele Ihorst, Annette Schmitt-Graeff, Dieter Herchenbach, Hassan Jumaa, Markus Warmuth, Hendrik Veelken, Christine Dierks
Journal: Blood
Blood (2012) 119 (4): 997–1007.
https://doi.org/10.1182/blood-2011-06-359075
Published: 2012
Includes: Supplemental data
Journal Articles

Dissecting the Hematopoietic Niche to Improve Transplant: Hedgehog and Wnt Pathways Activation in Fetal Mesenchymal Cells (MSC) Are Associated with Better Support to Hematopoietic Progenitors and Higher Proliferative Capacity Compared to Adult MSC

Marina Podestà, PhD, Daniela Cilloni, MD, PhD, Elena Ponomareva, Clara Cassanelli, Claudia Cossu, Biol Sci, Federica Benvenuto, Paola Anserini, Ezio Fulcheri, Katia Mareschi, Giuseppe Saglio, MD, Franca Fagioli, MD, Francesco Frassoni, MD
Journal: Blood
Blood (2011) 118 (21): 4809.
https://doi.org/10.1182/blood.V118.21.4809.4809
Published: 2011