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Journal Articles

Preliminary Clinical Data from a Phase 1 Trial with CPI-818, a Selective ITK Inhibitor That Preferentially Blocks the Growth of T Lymphoma Cells

Free
Patrick P. Ng, PhD, Mehrdad Mobasher, MD MPH, Kitman S. Yeung, MS, Andrew N. Hotson, PhD, Craig M. Hill, PhD, Antonett Madriaga, MS, Trang P. Dao-Pick, MA, Erik Verner, PhD, Dejan Radeski, MBBS, FRACP, FRCPA, Michael S. Khodadoust, MD PhD, Youn H. Kim, MD, Richard A. Miller, MD, Joseph J. Buggy, PhD, James W. Janc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1571.
https://doi.org/10.1182/blood-2019-127338
Published: 2019
Journal Articles

Randomized Phase II Trial of Combination Idiotype Vaccine and Adoptive Cell Transfer of Costimulated Autologous T Cells in Patients with Multiple Myeloma Post-Autotransplantation

Free
Muzaffar H. Qazilbash, MD, Edward A Stadtmauer, MD, Veera Baladandayuthapani, PhD, Heather Lin, Beryl Tross, RN, Medhavi Honhar, Soung-chul Cha, PhD, Kunhwa Kim, MDMPH, Michael Popescu, Nina Shah, MD, Qaiser Bashir, MD MBBS, Krina K. Patel, MDMSc, Vincent Young Lee, Elizabeth J Shpall, MD, Donna M. Weber, MD, Sheeba K. Thomas, MD, Robert Z. Orlowski, MD PhD, Naseem Kerr, MPH, Alfred L. Garfall, MD, Adam D. Cohen, MD, Dan T. Vogl, MD, Karen Dengel, BSN, RN, Carl H June, MD, Richard E Champlin, MD, Larry W Kwak, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3193.
https://doi.org/10.1182/blood.V130.Suppl_1.3193.3193
Published: 2017
Journal Articles

Randomized Phase II Trial of Combination Idiotype Vaccine and Anti-CD3/Anti-CD28 Costimulated Autologous T Cells in Patients with Multiple Myeloma Post-Autotransplantation

Free
Muzaffar H. Qazilbash, MD, Edward A Stadtmauer, MD, Veera Baladandayuthapani, PhD, Heather Lin, M.S., Beryl M. Tross, Medhavi Honhar, MBBS, Soung-Chul Cha, PhD, Kunhwa Kim, MD, Sheetal S Rao, PhD, Michael Popescu, MD, Nina Shah, MD, Qaiser Bashir, MD, Krina Patel, MD, Elizabeth J. Shpall, MD, Donna M. Weber, MD, Sheeba K. Thomas, MD, Jatin J. Shah, MD, Robert Z. Orlowski, PhD, MD, Naseem DS Kerr, MPH, Alfred L. Garfall, MD, Adam D. Cohen, MD, Karen Dengel, BSN, RN, Carl H June, MD, Richard E. Champlin, MD, Larry Kwak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4548.
https://doi.org/10.1182/blood.V128.22.4548.4548
Published: 2016
Journal Articles

Quantitative Baseline Circulating Tumor DNA Levels Correlate with GM-CSF Response to Idiotype Vaccine in Untreated Mantle Cell Lymphoma

Free
Mark Roschewski, MD, Kieron Dunleavy, MD, Sattva S. Neelapu, MD, Stefania Pittaluga, MD PhD, Christopher Joseph Melani, MD, Elaine S. Jaffe, MD, Margaret Shovlin, RN, Beryl Crossley, BS, Katie Kong, BS, Allison Jacob, MD, Larry Kwak, Wyndham H. Wilson, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2943.
https://doi.org/10.1182/blood.V128.22.2943.2943
Published: 2016
Journal Articles

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Free
Jian Yu, PhD, Bing Cui, Ph.D., George F. Widhopf, II, PhD, Liguang Chen, MD, PhD, Laura Rassenti, PhD, Zhengran Wang, BS, Shuyu Ma, BS, Tomoko Hayashi, M.D., Ph.D., Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4174.
https://doi.org/10.1182/blood.V122.21.4174.4174
Published: 2013
Journal Articles

Pharmacodynamic Activity and Preclinical Safety of CSL362, a Novel Humanised, Affinity Matured Monoclonal Antibody Against Human Interleukin 3 Receptor

Free
Eva Herzog, Samantha Busfield, PhD, Mark Biondo, PhD, Gino Vairo, Mark DeWitte, VMD, Ingo Pragst, Gerhard Dickneite, Prof. PhD, Andrew Nash, PhD, Sabine Zollner
Journal: Blood
Blood (2012) 120 (21): 1524.
https://doi.org/10.1182/blood.V120.21.1524.1524
Published: 2012
Journal Articles

Functional Adaptive Immune Responses in Hematopoietic Chimeric Mice After Umbilical Cord Blood Cell Transplantation.

Free
Hideaki Sato, Ayumi Wakayama, Kyoko Ito, Ikuo Kashiwakura, Koichi Ito
Journal: Blood
Blood (2012) 120 (21): 2995.
https://doi.org/10.1182/blood.V120.21.2995.2995
Published: 2012
Journal Articles

A Pilot Trial of WT1 Peptide-Loaded Allogeneic Dendritic Cell Vaccine and Donor Lymphocyte Infusion for WT1-Expressing Hematologic Malignancies and Post-Transplant Relapse

Free
Nirali N Shah, MD, David Loeb, MD, PhD, Hahn Khuu, MD, David Stroncek, MD, Mark Raffeld, MD, Cindy Delbrook, RN, Kelly Richards, RN, Kristin Baird, MD, Jason Levine, MD, Susan F. Leitman, MD, Crystal L Mackall, MD, Terry J Fry, MD, Alan S Wayne, MD
Journal: Blood
Blood (2011) 118 (21): 3055.
https://doi.org/10.1182/blood.V118.21.3055.3055
Published: 2011
Journal Articles

Eleven-Year Follow-up of Idiotype Vaccine and DA-EPOCH-Rituximab in Untreated Mantle Cell Lymphoma: Correlation of Survival with Idiotype Immune Response

Free
Cliona Grant, MD, Sattva S. Neelapu, MD, Larry W Kwak, MD, PhD, Kieron Dunleavy, MD, Therese White, RN, Barry W. Miller, MS, Elaine S. Jaffe, MD, Seth M. Steinberg, PhD, Brian Healey Bird, MB, MRCP, Wyndham H. Wilson, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2707.
https://doi.org/10.1182/blood.V118.21.2707.2707
Published: 2011
Journal Articles

Idiotype Immunization Following High-Dose Therapy and Autologous Stem Cell Transplantation for Non-Hodgkin Lymphoma,

Free
Caitlin L. Costello, MD, Peter Holman, MD, Margarida de Magalhaes-Silverman, MD, Sue Corringham, R.N., Januario E. Castro, M.D., Edward D. Ball, M.D.
Journal: Blood
Blood (2011) 118 (21): 4036.
https://doi.org/10.1182/blood.V118.21.4036.4036
Published: 2011
Journal Articles

Idiotypic Vaccination of Patients with Relapsed Follicular Lymphoma Using a Novel Vaccine Formulation Including a Tobacco Plant-Produced Tumor Specific Idiotype

Free
Maurizio Bendandi, MD, PhD, Carlos Becerra, MD, Joseph Kuhn, MD, Suncica Hukic, Nyla Langford, Taizoon Khokhar, Victor Klimyuk, PhD, Yuri Gleba, PhD, Romy Kandzia, PhD, Frank Thieme, PhD, Franziska Jarczowski, Jens Uwe Kuenstler, PhD, Madhuri Vusirikala, MD, Nora Ku, MD, Robert H. Collins, Jr., MD
Journal: Blood
Blood (2011) 118 (21): 1649.
https://doi.org/10.1182/blood.V118.21.1649.1649
Published: 2011
Journal Articles

Superior Immunogenicity of Idiotype Fab Fragments As Compared to Entire Immunoglobulin for Active Lymphoma Immunotherapy

Free
Marcelo A. Navarrete, M.D., Benjamin Kisser, Hendrik J. Veelken, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1633.
https://doi.org/10.1182/blood.V118.21.1633.1633
Published: 2011
Journal Articles

Cross Reactivity of Rabbit Anti-Recothrom (Human Recombinant Thrombin) Antibodies with Molecular Variants of Human Thrombin, and Various Bovine Thrombin Preparations

Free
Nasir Sadeghi, MS, Josephine Cunanan, MD, Debra Hoppensteadt, Ph.D., Indermohan Thethi, MD, Rakesh Wahi, MD, Jawed Fareed, PhD
Journal: Blood
Blood (2010) 116 (21): 4418.
https://doi.org/10.1182/blood.V116.21.4418.4418
Published: 2010
Journal Articles

Vaccination with IgM but Not IgG Idiotype Prolongs Remission Duration In Follicular Lymphoma Patients

Free
Stephen J. Schuster, Carlos F. Santos, Sattva S. Neelapu, Donald A. Berry, Mihaela A. Popa, Amy M. McCord, Elise A. Chong, Larry Kwak
Journal: Blood
Blood (2010) 116 (21): 429.
https://doi.org/10.1182/blood.V116.21.429.429
Published: 2010
Journal Articles

Leuprolide Acetate (GnRH Agonist) to Enhance Immune Function Post-Autologous Hematopoietic Stem Cell Transplantation (HSCT)

Free
Richard Champlin, Eva C. Guinan, MD, Lee M. Nadler, MD, Patricia McAdams, RN, Lisa Brennan, RN, Christine Barbon, MS, Ping Jiang, MS, Kristof Chwalisz, MD, PhD, Cynthia Mattia-Goldberg, Karim Sajwani, MS, Richard Boyd, MD, Peter F. Thall, PhD, Robertson Parkman, MD
Journal: Blood
Blood (2010) 116 (21): 4292.
https://doi.org/10.1182/blood.V116.21.4292.4292
Published: 2010
Journal Articles

Reconstitution of B-1a Cells in Murine Allogeneic Transplantation of Umbilical Cord Blood Cells: A New Advantage of the Umbilical Cord Blood-Derived Hematopoietic System.

Free
Hideaki Sato, Kyoko Ito, Nobukata Shinohara, Koichi Ito
Journal: Blood
Blood (2009) 114 (22): 2427.
https://doi.org/10.1182/blood.V114.22.2427.2427
Published: 2009
Journal Articles

Analysis of Antigen-Specific T-Cell Responses and Regulatory T Cells Following Sibling Donor Immunization with Patient-Derived Idiotype Vaccine Prior to Non-Myeloablative Allogeneic Stem Cell Transplantation for Multiple Myeloma.

Free
Myriam Foglietta, MD, Sattva Neelapu, M.D., Daniel H. Fowler, Seth M. Steinberg, Larry W. Kwak, Michael R. Bishop
Journal: Blood
Blood (2009) 114 (22): 2250.
https://doi.org/10.1182/blood.V114.22.2250.2250
Published: 2009
Journal Articles

Novel Anti-CD19/Idiotype Bispecific Diabody Vaccine for B-Cell Lymphoma.

Free
Patrick P. Ng, Ming Jia, Alejandro Virrueta, Kedar Patel, James R. Swartz, Shoshana Levy, Ronald Levy
Journal: Blood
Blood (2009) 114 (22): 2712.
https://doi.org/10.1182/blood.V114.22.2712.2712
Published: 2009
Journal Articles

Evaluation of Humoral Immune Responses to Vaccination with Tetanus Toxoid and KLH in Rituximab-Treated Follicular Non-Hodgkin’s Lymphoma Patients Compared to Healthy Volunteers

Free
M. Wayne Saville, MD, FACP, FRCPA, Nancy Valente, MD, Rachelle Perea, Kye Gilder, Judith Berlfein, Ilya Zyuzgin, PhD, David Belada, MD., PhD., Andre Banat, MD, MBA, Tudor Ciuleanu, MD
Journal: Blood
Blood (2008) 112 (11): 3066.
https://doi.org/10.1182/blood.V112.11.3066.3066
Published: 2008
Journal Articles

Antigen-specific human T-cell responses and T cell–dependent production of human antibodies in a humanized mouse model

Free
Brief Report
Noriko Tonomura, Katsuyoshi Habiro, Akira Shimizu, Megan Sykes, Yong-Guang Yang
Journal: Blood
Blood (2008) 111 (8): 4293–4296.
https://doi.org/10.1182/blood-2007-11-121319
Published: 2008
Includes: Supplemental data