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Journal Articles

Heme Attenuates T Cell Exhaustion and Drives Effector Function: Implications for Immune and Adoptive T Cell Therapy

Pulkit Gupta, Heather Lin, Remya Nair, Ruby Freeman, Dejah Blake, Kiran Lakhani, Doris R. Powell, Sagar Lonial, Benjamin G. Barwick, Ajay K. Nooka, Sarwish Rafiq, Mala Shanmugam
Journal: Blood
Blood (2023) 142 (Supplement 1): 6807.
https://doi.org/10.1182/blood-2023-186634
Published: 2023
Journal Articles

Initial Clinical Results and Immune Correlates of a Phase 2 Study of Daratumumab, Bortezomib, Dexamethasone Followed By a Proteasome Inhibitor in -Class Transition ( i CT) to Daratumumab, Ixazomib, Dexamethasone in Relapsed Refractory Multiple Myeloma

Hans C. Lee, June Li, Heather Lin, Astrid D. Murga, Gabriela M Rodriguez, Mostafa E. Mohamed, Jared Henderson, Sarah Rodriguez, Melody R. Becnel, Donna M. Weber, Swami P. Iyer, Gregory P. Kaufman, Sheeba K. Thomas, Elisabet E. Manasanch, Krina K. Patel, Stephen J. Noga, Michael R. Green, Robert Z. Orlowski, Cara L Haymaker
Journal: Blood
Blood (2023) 142 (Supplement 1): 4760.
https://doi.org/10.1182/blood-2023-188201
Published: 2023
Journal Articles

Antagonizing Vasoactive Intestinal Peptide (VIP) Receptors on CAR T Cells Improves Efficacy and Persistence

Heather Lin, Dejah Blake, Abhijay Mudigonda, Alysa N Evans, Ruby Freeman, Tanisha Sinha, Fan Fei, Elyse Christensen, Tenzin Passang Fnu, Sruthi Ravindranathan, Tongrui Liu, Lily Yang, Edmund K. Waller, Sarwish Rafiq
Journal: Blood
Blood (2023) 142 (Supplement 1): 4806.
https://doi.org/10.1182/blood-2023-182952
Published: 2023
Journal Articles

Engineering Novel Multi-Cytokine Backpacks for Manufacturing Functionally Improved CAR T Cell Products

Heather Lin, A K M Nawshad Hossian, Biaggio Uricoli, Ruby Mei Freeman, Dejah A Blake, Jonathan Legier, Remya Nair, Jean L. Koff, Mala Shanmugam, Erik Dreaden, Sarwish Rafiq
Journal: Blood
Blood (2022) 140 (Supplement 1): 10245–10246.
https://doi.org/10.1182/blood-2022-162498
Published: 2022
Journal Articles

A randomized phase 2 trial of idiotype vaccination and adoptive autologous T-cell transfer in patients with multiple myeloma

Clinical Trials & Observations
Muzaffar H. Qazilbash, Neeraj Y. Saini, Soung-chul Cha, Zhe Wang, Edward A. Stadtmauer, Veerabhadran Baladandayuthapani, Heather Lin, Beryl Tross, Medhavi Honhar, Sheetal S. Rao, Kunhwa Kim, Michael Popescu, Szymon Szymura, Tiantian Zhang, Aaron Anderson, Qaiser Bashir, Elizabeth J. Shpall, Robert Z. Orlowski, Bruce L. Levine, Naseem Kerr, Alfred Garfall, Adam Cohen, Dan T. Vogl, Karen Dengel, Carl H. June, Richard Champlin, Larry W. Kwak
Journal: Blood
Blood (2022) 139 (9): 1289–1301.
https://doi.org/10.1182/blood.2020008493
Published: 2022
Includes: Supplemental data
Journal Articles

Randomized Phase II Trial of Combination Idiotype Vaccine and Adoptive Cell Transfer of Costimulated Autologous T Cells in Patients with Multiple Myeloma Post-Autotransplantation

Muzaffar H. Qazilbash, MD, Edward A Stadtmauer, MD, Veera Baladandayuthapani, PhD, Heather Lin, Beryl Tross, RN, Medhavi Honhar, Soung-chul Cha, PhD, Kunhwa Kim, MDMPH, Michael Popescu, Nina Shah, MD, Qaiser Bashir, MD MBBS, Krina K. Patel, MDMSc, Vincent Young Lee, Elizabeth J Shpall, MD, Donna M. Weber, MD, Sheeba K. Thomas, MD, Robert Z. Orlowski, MD PhD, Naseem Kerr, MPH, Alfred L. Garfall, MD, Adam D. Cohen, MD, Dan T. Vogl, MD, Karen Dengel, BSN, RN, Carl H June, MD, Richard E Champlin, MD, Larry W Kwak, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3193.
https://doi.org/10.1182/blood.V130.Suppl_1.3193.3193
Published: 2017
Journal Articles

Randomized Phase II Trial of Combination Idiotype Vaccine and Anti-CD3/Anti-CD28 Costimulated Autologous T Cells in Patients with Multiple Myeloma Post-Autotransplantation

Muzaffar H. Qazilbash, MD, Edward A Stadtmauer, MD, Veera Baladandayuthapani, PhD, Heather Lin, M.S., Beryl M. Tross, Medhavi Honhar, MBBS, Soung-Chul Cha, PhD, Kunhwa Kim, MD, Sheetal S Rao, PhD, Michael Popescu, MD, Nina Shah, MD, Qaiser Bashir, MD, Krina Patel, MD, Elizabeth J. Shpall, MD, Donna M. Weber, MD, Sheeba K. Thomas, MD, Jatin J. Shah, MD, Robert Z. Orlowski, PhD, MD, Naseem DS Kerr, MPH, Alfred L. Garfall, MD, Adam D. Cohen, MD, Karen Dengel, BSN, RN, Carl H June, MD, Richard E. Champlin, MD, Larry Kwak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4548.
https://doi.org/10.1182/blood.V128.22.4548.4548
Published: 2016
Journal Articles

RNA Polymerase I Inhibition with CX-5461 As a Novel Strategy to Target MYC in Multiple Myeloma

Hans Lee, MD, Hua Wang, PhD, Heather Lin, M.S., Veera Baladandayuthapani, PhD, Jin He, Richard Julian Jones, PhD, Isere Kuiatse, PhD, Dongmin Gu, MD, PhD, Zhiqiang Wang, PhD, Sean O'Brien, PhD, Jonathan J Keats, PhD, Jing Yang, PhD, Richard Eric Davis, MD, Robert Z. Orlowski, PhD, MD
Journal: Blood
Blood (2015) 126 (23): 3010.
https://doi.org/10.1182/blood.V126.23.3010.3010
Published: 2015
Journal Articles

Phase II Study of the c-Met Inhibitor ARQ 197 (Tivantinib) in Patients with Relapsed Multiple Myeloma.

Stephan Joseph Dorkhom, D.O., Shadia Zaman, Ph.D., Sheeba K. Thomas, MD, Raymond Alexanian, M.D., Jatin J. Shah, M.D., Donna M. Weber, M.D., Michael Wang, M.D., Martha L. Anderson, R.N., Veerabhadran Baladandayuthapani, Ph.D., Yan Heather Lin, Ph.D., Min Fu, Ph.D., Christine M. Stellrecht, Ph.D., Claudia Morales de Partovi, B.S., Varsha V. Gandhi, Ph.D., Robert Z. Orlowski, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2976.
https://doi.org/10.1182/blood.V120.21.2976.2976
Published: 2012
Journal Articles

Impact of Non High-Risk Chromosomal Abnormalities on the Outcome of Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma

Sairah Ahmed, MD, Heather Lin, PhD, Veera Baladandayuthapani, PhD, Mubeen A Khan, Gary Lu, MD, Gabriela Rondon, MD, Sofia Qureshi, Yvonne T Dinh, Qaiser Bashir, MD, Nina Shah, MD, Simrit Parmar, M.D., Chitra M Hosing, MD, Uday Popat, M.D., Sergio A Giralt, MD, Robert Z. Orlowski, MD, PhD, Jatin J Shah, MD, Richard Champlin, MD, Muzaffar H. Qazilbash, MD
Journal: Blood
Blood (2011) 118 (21): 333.
https://doi.org/10.1182/blood.V118.21.333.333
Published: 2011
Journal Articles

Response Before Autologous Hematopoietic Stem Cell Transplantation Is An Important Predictor of Outcome in Multiple Myeloma,

Shatha Farhan, MD, Heather Lin, PhD, Veerabhadran Baladandayuthapani, Nina Shah, MD, Qaiser Bashir, MD, Chitra M Hosing, MD, Uday Popat, M.D., Simrit Parmar, M.D., Yvonne T Dinh, Sofia Qureshi, Gabriela Rondon, MD, Sergio Giralt, MD, Richard Champlin, MD, Muzaffar H. Qazilbash, MD
Journal: Blood
Blood (2011) 118 (21): 4119.
https://doi.org/10.1182/blood.V118.21.4119.4119
Published: 2011