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Journal Articles

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Mariateresa Pettinato, Mariam Aghajan, PhD, Violante Olivari, MSc, Alessandro Dulja, MSc, Antonella Nai, PhD, Jessica Bordini, PhD, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, PhD, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2019) 134 (Supplement_1): 955.

https://doi.org/10.1182/blood-2019-126496

Published: 2019

Journal Articles

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Chloé Latour, Céline Besson-Fournier, Ophélie Gourbeyre, Delphine Meynard, PhD, Aguilar-Martinez Patricia, MD PhD, Marie-Paule Roth, MD, Helene Coppin, PhD

Blood (2017) 130 (Supplement 1): 226.

https://doi.org/10.1182/blood.V130.Suppl_1.226.226

Published: 2017

Journal Articles

Transferrin Receptor 2 and HFE Regulate Hepcidin Levels Independently of Bmp6 and Hemojuvelin

Céline Besson-Fournier, Chloé Latour, Ophélie Gourbeyre, Patricia Aguilar-Martinez, MD PhD, Laura Silvestri, PhD, Marie-Paule Roth, MD, Hélène Coppin, PhD

Blood (2014) 124 (21): 746.

https://doi.org/10.1182/blood.V124.21.746.746

Published: 2014

Journal Articles

The Erythroid Factor Erythroferrone and Its Role In Iron Homeostasis

Léon Kautz, PhD, Grace Jung, MS, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD

Blood (2013) 122 (21): 4.

https://doi.org/10.1182/blood.V122.21.4.4

Published: 2013

Journal Articles

High Levels of Soluble Serum Hemojuvelin in Patients with Congenital Dyserythropoietic Anemia Type I,

Hannah Tamary, MD, Joseph Kapelushnik, M.D, Galit Perez-Avraham, MD, Itai Levi, MD, Carole Brasse-Lagnel, MD, Hanna Shalev, MD

Blood (2011) 118 (21): 3179.

https://doi.org/10.1182/blood.V118.21.3179.3179

Published: 2011

Journal Articles

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

Wenjie Chen, Franklin W. Huang, Tomasa Barrientos de Renshaw, Nancy C. Andrews

Blood (2011) 117 (23): 6319–6325.

https://doi.org/10.1182/blood-2010-12-327957

Published: 2011

Includes: Supplemental data

Journal Articles

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

Paul J. Schmidt, Nancy C. Andrews, Mark D. Fleming

Blood (2010) 116 (25): 5679–5687.

https://doi.org/10.1182/blood-2010-04-277954

Published: 2010

Includes: Supplemental data

Journal Articles

Global Sequencing for the Molecular Background of Hereditary Hemochomatosis In Brazilian Patients

Elvira Maria Guerra-Shinohara, PhD, Paulo Caleb Santos, Rodolfo Cancado, MD, PhD, Alexandre Pereira, MD, PhD, Isolmar Schettert, MD, Renata Soares, Rosario D C Hirata, PhD, Mario H Hirata, PhD, Regina Pagliusi, Maria Stella Figueiredo, MD, PhD, José Eduardo Krieger, MD, PhD, Carlos Chiattone, MD, PhD

Blood (2010) 116 (21): 5146.

https://doi.org/10.1182/blood.V116.21.5146.5146

Published: 2010

Journal Articles

Novel Homozygous Mutation (R329X) in the Hemojuvelin Gene Is Associated with Hypogonadotrophic Hypogonadism, Diabetes Mellitus and Heart Failure Duo to Juvenile Hemochromatosis.

Rong-Fu Zhou, Sr, Jian Ouyang, Sr, Xue-mei Guo, Bing Chen, Sr, Jing-yan Xu, Xiao-Yan Shao, Qi-Guo Zhang

Blood (2009) 114 (22): 5102.

https://doi.org/10.1182/blood.V114.22.5102.5102

Published: 2009

Journal Articles

Iron overload in the Asian community

Blood (2009) 114 (1): 20–25.

https://doi.org/10.1182/blood-2009-01-199109

Published: 2009

Includes: Supplemental data

Journal Articles

Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells

Julia E. Maxson, Caroline A. Enns, An-Sheng Zhang

Blood (2009) 113 (8): 1786–1793.

https://doi.org/10.1182/blood-2008-08-174565

Published: 2009

Journal Articles

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

Jaroslav Truksa, Pauline Lee, Ernest Beutler

Blood (2009) 113 (3): 688–695.

https://doi.org/10.1182/blood-2008-05-160184

Published: 2009

Includes: Supplemental data

Journal Articles

The Zebrafish Ortholog of Hemojuvelin Participates in Notochord and Somite Development, but Fails to Regulate Embryonic Hepcidin Expression

Yann Gibert, Victoria J. Lattanzi, Jason Holzheimer, Sarah F. Burnett, Paula G. Fraenkel

Blood (2008) 112 (11): 118.

https://doi.org/10.1182/blood.V112.11.118.118

Published: 2008

Journal Articles

Processing of Hemojuvelin Requires Retrograde Trafficking to the Golgi in HepG2 Cells.

An-Sheng Zhang, Julia Julia Maxson, Caroline A Enns

Blood (2008) 112 (11): 3845.

https://doi.org/10.1182/blood.V112.11.3845.3845

Published: 2008

Journal Articles

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

Yin Xia, Jodie L. Babitt, Yisrael Sidis, Raymond T. Chung, Herbert Y. Lin

Blood (2008) 111 (10): 5195–5204.

https://doi.org/10.1182/blood-2007-09-111567

Published: 2008

Includes: Supplemental data

Journal Articles

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

Laura Silvestri, Alessia Pagani, Clara Camaschella

Blood (2008) 111 (2): 924–931.

https://doi.org/10.1182/blood-2007-07-100677

Published: 2008

Includes: Supplemental data

Journal Articles

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4

Lan Lin, Erika V. Valore, Elizabeta Nemeth, Julia B. Goodnough, Victoria Gabayan, Tomas Ganz

Blood (2007) 110 (6): 2182–2189.

https://doi.org/10.1182/blood-2007-04-087593

Published: 2007

Journal Articles

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

Laura Silvestri, Alessia Pagani, Claudia Fazi, Gianmario Gerardi, Sonia Levi, Paolo Arosio, Clara Camaschella

Blood (2007) 109 (10): 4503–4510.

https://doi.org/10.1182/blood-2006-08-041004

Published: 2007

Includes: Supplemental data

Journal Articles

Sensing Iron: Reciprocal Regulation of Hepcidin mRNA by Soluble and Cell-Associated Hemojuvelin.

Lan Lin, Y. Paul Goldberg, MD, Tomas Ganz, MD, PhD

Blood (2005) 106 (11): 512.

https://doi.org/10.1182/blood.V106.11.512.512

Published: 2005

Journal Articles

Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression.

Franklin W. Huang, BS, Jodie L. Babitt, MD, Diedra M. Wrighting, MS, Tarek A. Samad, PhD, Yin Xia, PhD, Yisrael Sidis, PhD, Jason A. Campagna, Raymond T. Chung, MD, Alan L. Schneyer, PhD, Clifford J. Woolf, PhD, Nancy C. Andrews, MD, PhD, Herbert Y. Lin, MD, PhD

Blood (2005) 106 (11): 511.

https://doi.org/10.1182/blood.V106.11.511.511

Published: 2005

NARROW

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Transferrin Receptor 2 and HFE Regulate Hepcidin Levels Independently of Bmp6 and Hemojuvelin

The Erythroid Factor Erythroferrone and Its Role In Iron Homeostasis

High Levels of Soluble Serum Hemojuvelin in Patients with Congenital Dyserythropoietic Anemia Type I,

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

Global Sequencing for the Molecular Background of Hereditary Hemochomatosis In Brazilian Patients

Novel Homozygous Mutation (R329X) in the Hemojuvelin Gene Is Associated with Hypogonadotrophic Hypogonadism, Diabetes Mellitus and Heart Failure Duo to Juvenile Hemochromatosis.

Iron overload in the Asian community

Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

The Zebrafish Ortholog of Hemojuvelin Participates in Notochord and Somite Development, but Fails to Regulate Embryonic Hepcidin Expression

Processing of Hemojuvelin Requires Retrograde Trafficking to the Golgi in HepG2 Cells.

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

Sensing Iron: Reciprocal Regulation of Hepcidin mRNA by Soluble and Cell-Associated Hemojuvelin.

Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression.

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American Society of Hematology

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American Society of Hematology

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