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Paula G. Fraenkel
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Journal Articles

Nicotinamide N-Methyltransferase Expression Decreases in Iron Overload Exacerbating Iron-Induced Hepatotoxicity

Tiago De Bone Koppe, MSc, Bonnie Patchen, BS, Aaron Cheng, BA, Manoj Bhasin, PhD, Chris D. Vulpe, MD, Jose M. Fernandez-Real, MD PhD, Robert K. Schwartz, MD PhD, Pavlos Pissios, PhD, Paula G. Fraenkel, MD
Journal: Blood
Blood (2016) 128 (22): 204.
https://doi.org/10.1182/blood.V128.22.204.204
Published: 2016
Journal Articles

Dietary Supplementation with Ipriflavone Decreases Liver Iron Loading in Wild Type Mice

Bonnie Patchen, Vera Gaun, Aaron Cheng, Paula G. Fraenkel, MD
Journal: Blood
Blood (2014) 124 (21): 4025.
https://doi.org/10.1182/blood.V124.21.4025.4025
Published: 2014
Journal Articles

Identification of Differentially Expressed Genes in Mice with Nutritional or Genetic Causes of Iron Overload

Aaron Cheng, Luke Schissler, Bonnie Patchen, Vera Gaun, Manoj Bhasin, PhD, Chris D. Vulpe, MD PhD, Paula G. Fraenkel, MD
Journal: Blood
Blood (2014) 124 (21): 2681.
https://doi.org/10.1182/blood.V124.21.2681.2681
Published: 2014
Journal Articles

Critical models for the anemia of inflammation

Paula G. Fraenkel
Journal: Blood
Blood (2014) 123 (8): 1124–1125.
https://doi.org/10.1182/blood-2014-01-546994
Published: 2014
Journal Articles

Granulocytes Infiltrate The Intestine In a Zebrafish Model Of Inflammatory Bowel Disease

Brenda Geiger, PhD, Aileen W. Zhen, Efi Kokkotou, MD, Paula G. Fraenkel, MD
Journal: Blood
Blood (2013) 122 (21): 2276.
https://doi.org/10.1182/blood.V122.21.2276.2276
Published: 2013
Journal Articles

Dietary Supplementation with Genistein Increases Hepcidin Expression in Wild Type Mice

Aileen W. Zhen, Josephine Volovetz, Paula G. Fraenkel, MD
Journal: Blood
Blood (2012) 120 (21): 3208.
https://doi.org/10.1182/blood.V120.21.3208.3208
Published: 2012
Journal Articles

A Screen for Small Molecules That Regulate Hepcidin Expression

Josephine Volovetz, Aileen W. Zhen, Vera Gaun, Bonnie Patchen, Paula G. Fraenkel, MD
Journal: Blood
Blood (2012) 120 (21): 611.
https://doi.org/10.1182/blood.V120.21.611.611
Published: 2012
Journal Articles

Treatment with the Small Molecule Genistein Increases Hepcidin Expression In Zebrafish Embryos and Human Hepatocytes

Yann Gibert, PhD, Aileen W. Zhen, Nancy H. Nguyen, Paula G. Fraenkel, MD
Journal: Blood
Blood (2010) 116 (21): 4245.
https://doi.org/10.1182/blood.V116.21.4245.4245
Published: 2010
Journal Articles

Knockdown of Matriptase-2 Increases Hepcidin Expression in a BMP-Dependent Manner in Zebrafish Embryos.

Yann Gibert, PhD, Victoria J. Lattanzi, Paula G. Fraenkel, MD
Journal: Blood
Blood (2009) 114 (22): 4050.
https://doi.org/10.1182/blood.V114.22.4050.4050
Published: 2009
Journal Articles

Transferrin-a modulates hepcidin expression in zebrafish embryos

Paula G. Fraenkel, Yann Gibert, Jason L. Holzheimer, Victoria J. Lattanzi, Sarah F. Burnett, Kimberly A. Dooley, Rebecca A. Wingert, Leonard I. Zon
Journal: Blood
Blood (2009) 113 (12): 2843–2850.
https://doi.org/10.1182/blood-2008-06-165340
Published: 2009
Includes: Supplemental data
Journal Articles

The Zebrafish Ortholog of Hemojuvelin Participates in Notochord and Somite Development, but Fails to Regulate Embryonic Hepcidin Expression

Yann Gibert, Victoria J. Lattanzi, Jason Holzheimer, Sarah F. Burnett, Paula G. Fraenkel
Journal: Blood
Blood (2008) 112 (11): 118.
https://doi.org/10.1182/blood.V112.11.118.118
Published: 2008
Journal Articles

Transferrin Acts as an Iron Sensor Upstream of BMP2b in the Zebrafish.

Paula G. Fraenkel, Sarah Burnett, Jason Holzheimer, Kim A. Dooley, Rebecca Wingert, Matthias Hammerschmidt, Leonard I. Zon
Journal: Blood
Blood (2007) 110 (11): 704.
https://doi.org/10.1182/blood.V110.11.704.704
Published: 2007
Journal Articles

Functional conservation of erythropoietin signaling in zebrafish

Noëlle Paffett-Lugassy, Nelson Hsia, Paula G. Fraenkel, Barry Paw, Irene Leshinsky, Bruce Barut, Nathan Bahary, Jaime Caro, Robert Handin, Leonard I. Zon
Journal: Blood
Blood (2007) 110 (7): 2718–2726.
https://doi.org/10.1182/blood-2006-04-016535
Published: 2007
Includes: Multimedia, Supplemental data
Journal Articles

Requirement of Transferrin for Iron-Induced Hepcidin Expression in the Zebrafish.

Paula G. Fraenkel, MD, Kim A. Dooley, Ph.D., Leonard I. Zon, M.D.
Journal: Blood
Blood (2006) 108 (11): 1538.
https://doi.org/10.1182/blood.V108.11.1538.1538
Published: 2006
Journal Articles

Ferroportin1-Deficient Zebrafish Treated with Iron Dextran Develop Anemia Despite Increased Macrophage Iron Stores.

Paula G. Fraenkel, M.D., David Traver, Ph.D., Adriana Donovan, Ph.D., Leonard I. Zon, M.D.
Journal: Blood
Blood (2004) 104 (11): 3691.
https://doi.org/10.1182/blood.V104.11.3691.3691
Published: 2004