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Journal Articles

Methotrexate and Cytarabine for Adult Patients with Newly Diagnosed Langerhans Cell Histiocytosis: A Single Arm, Single Center, Prospective Phase 2 Study

Xinxin Cao, Jian Li, MD, Ai-lin Zhao, Xue-min Gao, Hua-cong Cai, MD, Lu Zhang, MD, Yan Zhang, MD, Jun Feng, MD, Miao Chen, MD, Tie-nan Zhu, MD, Na Niu, Jian Sun, MD, Zhi-yong Liang, MD, Dao-Bin Zhou, Ming-hui Duan, MD

Blood (2019) 134 (Supplement_1): 294.

https://doi.org/10.1182/blood-2019-122220

Published: 2019

Journal Articles

Low-Dose BRAF-Inhibitors in the Treatment of Histiocytic Disorders with the BRAF-V600E Mutation

Gordon Ruan, MD, Gaurav Goyal, MBBS, Jithma P. Abeykoon, MD, N. Nora Bennani, MD, Karen Rech, MD, Jason Young, MD, Mithun Vinod Shah, MD PhD, Ronald S. Go, MD

Blood (2019) 134 (Supplement_1): 5895.

https://doi.org/10.1182/blood-2019-124891

Published: 2019

Journal Articles

Clinical Features and Outcomes of Unifocal Adult Langerhans Cell Histiocytosis

Marie Hu, MD, Gaurav Goyal, MBBS, Jason Young, MD, Karen Rech, MD, N. Nora Bennani, MD, Mithun Vinod Shah, MD PhD, Robert Vassallo, MD, Jay H Ryu, MD, Ronald S. Go, MD

Blood (2019) 134 (Supplement_1): 1667.

https://doi.org/10.1182/blood-2019-132104

Published: 2019

Journal Articles

Bone Marrow Harvest Volume and CD34+ Cell Count in Pediatric Sibling Donors: A Single Centre Retrospective Analysis

Awatif Alanazi, MD, Amir Nadeem, Khawar Siddiqui, Mouhab Ayas, MD, Ali Abdallah Ahmari, MD, Ibrahim A. Ghemlas, MD, Abdullah Aljefri, MD, Hawazen S. Alsaedi, MD, Amal Al-Seraihy, MD

Blood (2019) 134 (Supplement_1): 1969.

https://doi.org/10.1182/blood-2019-127655

Published: 2019

Journal Articles

Single-Agent Cladribine As an Effective Therapy for Adults with Langerhans Cell Histiocytosis

Gaurav Goyal, MBBS, Marie Hu, MD, Jithma P. Abeykoon, MD, Nora N Bennani, MD, Jay H Ryu, MD, Mithun Vinod Shah, MD PhD, Robert Vassallo, MD, Ronald S. Go, MD

Blood (2019) 134 (Supplement_1): 4189.

https://doi.org/10.1182/blood-2019-122334

Published: 2019

Journal Articles

Acquired Hematologic Disorders of Ras-MAPK Activation

Carl E. Allen, MD PhD

Blood (2018) 132 (Supplement 1): SCI-42.

https://doi.org/10.1182/blood-2018-99-109380

Published: 2018

Journal Articles

Clinical Features and Treatment Approaches in Patients with Rosai-Dorfman Disease: The Mayo Clinic Experience

Gaurav Goyal, MBBS, Aishwarya Ravindran, MBBS, Mrinal M. Patnaik, MDMBBS, Grzegorz S Nowakowski, MD, Gita Thanarajasingam, MD, Thomas M Habermann, MD, Taimur Sher, MD, Karen L Rech, MD, David J Inwards, MD, Patrick B Johnston, MD PhD, Robert Vassallo, MD, Sameer A. Parikh, MD, Ronald S. Go, MD

Blood (2017) 130 (Supplement 1): 3573.

https://doi.org/10.1182/blood.V130.Suppl_1.3573.3573

Published: 2017

Journal Articles

Incidence, Treatment Patterns, and Outcomes of Histiocytic Disorders in the United States: A Forty-Year Population Study

Sagar S. Patel, MD, Girish Kunapareddy, MD, Hetty E. Carraway, MD MBA, Aaron T. Gerds, MDMS, Anjali S. Advani, MD, Matt Kalaycio, MD, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD PhD MPH

Blood (2017) 130 (Supplement 1): 2266.

https://doi.org/10.1182/blood.V130.Suppl_1.2266.2266

Published: 2017

Journal Articles

Phase 2 Trial of Single-Agent Cobimetinib for Adults with BRAF V600-Mutant and Wild-Type Histiocytic Disorders

Eli L Diamond, MD, Benjamin H Durham, MD BS, Ahmet Dogan, MD PhD, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Gary Ulaner, MD, Lynn Brody, MD, Omar Abdel-Wahab, MD

Blood (2017) 130 (Supplement 1): 257.

https://doi.org/10.1182/blood.V130.Suppl_1.257.257

Published: 2017

Journal Articles

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults

Paul Milne, Venetia Bigley, Chris M. Bacon, Antoine Néel, Naomi McGovern, Simon Bomken, Muzlifah Haniffa, Eli L. Diamond, Benjamin H. Durham, Johannes Visser, David Hunt, Harsha Gunawardena, Mac Macheta, Kenneth L. McClain, Carl Allen, Omar Abdel-Wahab, Matthew Collin

Blood (2017) 130 (2): 167–175.

https://doi.org/10.1182/blood-2016-12-757823

Published: 2017

Includes: Supplemental data

Journal Articles

Real-Time Genomic Profiling Identifies Novel Mutations and Improved Therapy for Histiocytoses

Lynn Lee, MD, Anjelika Gasilina, Jayeeta Roychoudhury, PhD, Jason Clark, Francis X McCormack, MD, Joseph Gerald Pressey, MD, Robert B. Lorsbach, MD PhD, Siraj M Ali, MD PhD, Mark Bailey, MSc, Philip Stevens, PhD, Jeffrey S Ross, MD, Vincent A. Miller, MD, Nicolas Nassar, PhD, Ashish R Kumar, MBBS, PhD

Blood (2016) 128 (22): 2723.

https://doi.org/10.1182/blood.V128.22.2723.2723

Published: 2016

Journal Articles

Efficacy and Toxicity Profile of Clofarabine in Patients with Recurrent/Refractory Langerhans Cell Histiocytosis and Other Histiocytic Disorders

Olive S. Eckstein, MD, Racheal Bingham, CPNP, Erin Christine Peckham, PhD MPH, Austin Brown, MPH, PhD, Carl E. Allen, MD PhD, Kenneth L. McClain, MD PhD

Blood (2016) 128 (22): 1329.

https://doi.org/10.1182/blood.V128.22.1329.1329

Published: 2016

Journal Articles

The Nationwide Study of Erdheim-Chester Disease in Japan

Mizuki Ogura, MD, PhD, Takashi Toya, MD, PhD, Akihide Yoshimi, MD, PhD, Aya Shinozaki Ushiku, MD, PhD, Akira Honda, MD, PhD, Toyama Kazuhiro, MD, PhD, Kenjiro Honda, MD, PhD, Yasuhito Nannya, MD, PhD, Yusuke Shinoda, MD, PhD, Akiko M. Saito, MD PhD, Takashi Ogura, MD, Ichiro Katayama, MD, PhD, Kiyoshi Miyagawa, MD, PhD, Masaomi Nangaku, MD, PhD, Masashi Fukayama, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2016) 128 (22): 4879.

https://doi.org/10.1182/blood.V128.22.4879.4879

Published: 2016

Journal Articles

Hemophagocytic Lymphohistiocytosis (HLH) in Langerhans Cell Histiocytosis (LCH): A Multicenter Retrospective Descriptional Study

Deepak Chellapandian, MD MBBS, Rui Zhang, MD, Michael Jeng, MD, Cor Van Den Bos, MD PhD, Vicente Santa-María López, MD, Kai Lehmberg, MD, Elena Sieni, MD, Yini Wang, MD, Taizo Allen Nakano, MD, James Williams, MD, Nicholas J. Fustino, MD, Itziar Astigarraga, MD, Ira Dunkel, MD, Qi An, Cheng Cheng, PhD, Sheila Weitzman, MB BCh, FRCP, Lillian Sung, MD PhD, Kim E. Nichols, MD

Blood (2016) 128 (22): 707.

https://doi.org/10.1182/blood.V128.22.707.707

Published: 2016

Journal Articles

Cooperative Activity of BRAF F595L and Mutant HRAS in Histiocytic Sarcoma Provides New Insights into Oncogenic BRAF Signaling

Maximilian Kordes, Michael Röring, Christoph Heining, Sandra Braun, Barbara Hutter, Daniela Richter, Christina Geörg, Claudia Scholl, Wilfried Roth, Andreas Rosenwald, MD, Eva Geissinger, Christof von Kalle, Dirk Jäger, Benedikt Brors, Wilko Weichert, Carsten Grüllich, Hanno Glimm, Tilman Brummer, PhD, Stefan Fröhling

Blood (2015) 126 (23): 1631.

https://doi.org/10.1182/blood.V126.23.1631.1631

Published: 2015

Journal Articles

The Efficacy of Vemurafenib in Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Preliminary Results from VE-Basket Study

David M. Hyman, MD, Eli Diamond, Vivek Subbiah, MD, Jean-Yves Blay, MD PhD, A. Craig Lockhart, Omar Abdel-Wahab, MD, Florin Sirzen, Maria Luisa Veronese, MD, Susan Frances Laserre, Elena Elez, Jose Baselga, MD PhD

Blood (2014) 124 (21): 635.

https://doi.org/10.1182/blood.V124.21.635.635

Published: 2014

Journal Articles

Mutually Exclusive Recurrent Somatic Mutations in MAP2K1 and BRAF Support a Central Role for ERK Activation in LCH Pathogenesis

Rikhia Chakraborty, PhD

Blood (2014) 124 (21): 5587.

https://doi.org/10.1182/blood.V124.21.5587.5587

Published: 2014

Journal Articles

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Benjamin Durham, MD, Jing Ma, PhD, Eunhee Kim, PhD, John K. Choi, MD, Patrick Campbell, MD PhD, Juvianee Estrada-Veras, MD, Michael P Walsh, PhD, Mario E Lacouture, MD, Young Rock Chung, MS, Joy Nakitandwe, PhD, Eli Diamond, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Minal Patel, Christopher Y. Park, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1887.

https://doi.org/10.1182/blood.V124.21.1887.1887

Published: 2014

Journal Articles

Prospective Blinded Study of BRAF V600E Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders

David M. Hyman, MD, Eli Diamond, Cecile Rose Vibat, Latifa Hassaine, Jason Poole, Minal Patel, Veronica Holley, Goran Cabrilo, Timothy T. Lu, Maria Arcila, MD, Young Rock Chung, MS, Raajit K. Rampal, MD PhD, Funda Meric-Bernstam, MD, Jose Baselga, MD PhD, Razelle Kurzrock, MD, Mark Erlander, Filip Janku, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1833.

https://doi.org/10.1182/blood.V124.21.1833.1833

Published: 2014

Journal Articles

Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis

Blood (2014) 124 (19): 3007–3015.

https://doi.org/10.1182/blood-2014-05-577825

Published: 2014

Includes: Supplemental data

NARROW

Methotrexate and Cytarabine for Adult Patients with Newly Diagnosed Langerhans Cell Histiocytosis: A Single Arm, Single Center, Prospective Phase 2 Study

Low-Dose BRAF-Inhibitors in the Treatment of Histiocytic Disorders with the BRAF-V600E Mutation

Clinical Features and Outcomes of Unifocal Adult Langerhans Cell Histiocytosis

Bone Marrow Harvest Volume and CD34+ Cell Count in Pediatric Sibling Donors: A Single Centre Retrospective Analysis

Single-Agent Cladribine As an Effective Therapy for Adults with Langerhans Cell Histiocytosis

Acquired Hematologic Disorders of Ras-MAPK Activation

Clinical Features and Treatment Approaches in Patients with Rosai-Dorfman Disease: The Mayo Clinic Experience

Incidence, Treatment Patterns, and Outcomes of Histiocytic Disorders in the United States: A Forty-Year Population Study

Phase 2 Trial of Single-Agent Cobimetinib for Adults with BRAF V600-Mutant and Wild-Type Histiocytic Disorders

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults

Real-Time Genomic Profiling Identifies Novel Mutations and Improved Therapy for Histiocytoses

Efficacy and Toxicity Profile of Clofarabine in Patients with Recurrent/Refractory Langerhans Cell Histiocytosis and Other Histiocytic Disorders

The Nationwide Study of Erdheim-Chester Disease in Japan

Hemophagocytic Lymphohistiocytosis (HLH) in Langerhans Cell Histiocytosis (LCH): A Multicenter Retrospective Descriptional Study

Cooperative Activity of BRAF F595L and Mutant HRAS in Histiocytic Sarcoma Provides New Insights into Oncogenic BRAF Signaling

The Efficacy of Vemurafenib in Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Preliminary Results from VE-Basket Study

Mutually Exclusive Recurrent Somatic Mutations in MAP2K1 and BRAF Support a Central Role for ERK Activation in LCH Pathogenesis

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Prospective Blinded Study of BRAF V600E Mutation Detection in Cell-Free DNA of Patients with Systemic Histiocytic Disorders

Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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