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Journal Articles

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Chaitanya Yenumula, MD, Srikanth Talluri, PhD, Tommaso Perini, MD, Subodh Kumar, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4467.

https://doi.org/10.1182/blood-2018-99-119346

Published: 2018

Journal Articles

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Blood (2018) 132 (Supplement 1): 3268.

https://doi.org/10.1182/blood-2018-99-119444

Published: 2018

Journal Articles

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Puru Nanjappa, Chaitanya Yenumula, MD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4333.

https://doi.org/10.1182/blood.V130.Suppl_1.4333.4333

Published: 2017

Journal Articles

The Immunomodulatory Drugs, through Loss of Ikaros and Aiolos, Derepress CD38 and Functionally Synergise with Daratumumab

Pasquale L. Fedele, FRACP, FRCPA, Simon Willis, PhD, Michael S. Low, MBBS, Jai Rautela, PhD, David H. Segal, PhD, Jianan Gong, PhD, Yang Liao, PhD, Nicholas Huntington, PhD, Wei Shi, PhD, David Huang, MBBS PhD, George Grigoriadis, MBBS PhDFRACP FRCPA, Julie Tellier, PhD, Stephen Nutt, PhD

Blood (2017) 130 (Supplement 1): 1801.

https://doi.org/10.1182/blood.V130.Suppl_1.1801.1801

Published: 2017

Journal Articles

Inhibition of CDK4/CDK6 Sensitizes Myeloma to IMiD By Reducing the MEIS2 to Cereblon Ratio That Accelerates IKZF1 and IKZF3 Degradation

Xiangao Huang, PhD, David Jayabalan, BSMS, MSc, Maurizio Di Liberto, PhD, Zhengming Chen, PhD, Anna C Schinzel, PhD, Scott Ely, MD MPH, Adriana C Rossi, MD MHS, Roger N Pearse, MD PhD, Ekta Aneja, MBBS, Morton Coleman, MD, Joseph M Lane, MD, William C. Hahn, MD PhD, Tomer M Mark, MD MSc, Ruben Niesvizky, MD, Selina Chen-Kiang, PhD

Blood (2015) 126 (23): 500.

https://doi.org/10.1182/blood.V126.23.500.500

Published: 2015

Journal Articles

No Development of Neutralizing Antibodies Against Recombinant Interferon-Alpha in Ph-Negative Myeloproliferative Neoplasms - a Prospective Study

Lukas Frans Ocias, Dennis Lund Hansen, Thomas Kielsgaard Kristensen, Karin de Stricker, Daniel El Fassi, MD PhD, Jesper Stentoft, Jørn Starklint, Mikael Frederiksen, Marianne Tang Severinsen, Ole Weis Bjerrum, MD DMSc, Peter Møller, Torben Mourits-Andersen, MD, Ulrik Malthe Overgaard, Hans Carl Hasselbalch, MD Professor, DMSc, Klaus Bendtzen, Thomas Stauffer Larsen, MD PhD

Blood (2015) 126 (23): 5177.

https://doi.org/10.1182/blood.V126.23.5177.5177

Published: 2015

Journal Articles

Surface Ifitms on Megakaryocytes and Platelets Regulate Fibrinogen Endocytosis Under Inflammatory Conditions

Robert A. Campbell, PhD, Jesse W Rowley, PhD, Andrew S. Weyrich, PhD, Matthew T. Rondina, MD

Blood (2015) 126 (23): 1034.

https://doi.org/10.1182/blood.V126.23.1034.1034

Published: 2015

Journal Articles

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Kazuhiro Mochizuki, MD PhD, Lijun Meng, Izumi Mochizuki, MD, Qing Tong, MD, Shan He, Yongnian Liu, Janaki Purushe, Hongxing Sun, Henry Fung, Raza Zaidi, Ran Reshef, MD, Bruce R. Blazar, MD, Hideo Yagita, PhD, Shin Mineishi, MD, Yi Zhang

Blood (2015) 126 (23): 233.

https://doi.org/10.1182/blood.V126.23.233.233

Published: 2015

Journal Articles

Age-Associated Bone Disease in Factor VIII-Deficient Mice

Emily A. Larson, Urszula T. Iwaniec, PhD, Sigrid C. Holmgren, MS, Russell T. Turner, PhD, Michael Recht, MD PhD, Jason A. Taylor, MD PhD

Blood (2014) 124 (21): 2798.

https://doi.org/10.1182/blood.V124.21.2798.2798

Published: 2014

Journal Articles

IAP Antagonists Are a Novel Class Of Immunomodulators That Induce Complete Response In Vk*MYC Myeloma By Stimulating Plasmacytoid Dendritic Cells To Secrete IFNa

Marta Chesi, PhD, Victoria Garbitt, Stephen Palmer, P. Leif Bergsagel, MD

Blood (2013) 122 (21): 128.

https://doi.org/10.1182/blood.V122.21.128.128

Published: 2013

Journal Articles

Negative Regulation of Eosinophil Production by Toll-Like Receptors

Kaila L. Schollaert, MS, Melissa K. Mingler, MBA, Marc E. Rothenberg, MD, PhD, Patricia C. Fulkerson, MD, PhD

Blood (2012) 120 (21): 1237.

https://doi.org/10.1182/blood.V120.21.1237.1237

Published: 2012

Journal Articles

Synergistic Loss of IRF4 and Induction of IRF7 Sensitizes Primary Myeloma Cells to IMiD Killing by IFNβ in Prolonged Early G1 Arrest Induced by CDK4/CDK6 Inhibition

Xiangao Huang, PhD, David Jayabalan, B.S.M.S, Maurizio Di Liberto, Ph.D., Jackson D Harvey, B.S., Anna C. Schinzel, PhD, Tomer M Mark, MD, MSc, Mohamad Hussein, MD, Sophia Randolph, MD, PhD, William C. Hahn, MD, PhD, Ruben Niesvizky, MD, Selina Chen-Kiang, PhD

Blood (2012) 120 (21): 572.

https://doi.org/10.1182/blood.V120.21.572.572

Published: 2012

Journal Articles

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Kazuhiro Mochizuki, MD, PhD, Fang Xie, MD, Shan He, PhD, Qing Tong, MS, Yongnian Liu, MS, Yajun Guo, MD, PhD, Koji Kato, MD, PhD, Hideo Yagita, PhD, Shin Mineishi, Yi Zhang, MD, PhD

Blood (2012) 120 (21): 337.

https://doi.org/10.1182/blood.V120.21.337.337

Published: 2012

Journal Articles

Episomal Anchorage Maintains Non-Integrating Lentiviral Vectors in Dividing Cells

Santhosh Chakkaramakkil Verghese, Ph.D, Amy M. Skinner, Ph.D., Karen L Huan, Hans J Lipps, Ph.D, Peter Kurre, MD

Blood (2012) 120 (21): 4224.

https://doi.org/10.1182/blood.V120.21.4224.4224

Published: 2012

Journal Articles

Clopidogrel, a P2Y12 Receptor Antagonist, Potentiates the Inflammatory Response in a Rat Model of Peptidoglycan Polysaccharide - Induced Arthritis,

Analia E Garcia, DMD, Sripal R Mada, PhD, Mario C Rico, MD, Raul A. De La Cadena, MD, Satya P. Kunapuli, PhD

Blood (2011) 118 (21): 3287.

https://doi.org/10.1182/blood.V118.21.3287.3287

Published: 2011

Journal Articles

Upregulation of hGC-1 Expression by Hypomethylation, Retinoic Acid and Interferons in Human Myeloid Leukemia

Wenli Liu, Griffin P Rodgers

Blood (2008) 112 (11): 4486.

https://doi.org/10.1182/blood.V112.11.4486.4486

Published: 2008

Journal Articles

Regulation of TLR Expression and Activation in Human Mesenchymal Stromal Cells by IFN-a, IFN-g and TNF-a.

Moïra François, Raphaëlle Romieu-Mourez, Marie-Noëlle Boivin, Jacques Galipeau

Blood (2007) 110 (11): 1790.

https://doi.org/10.1182/blood.V110.11.1790.1790

Published: 2007

Journal Articles

Mesenchymal Stem Cells Selectively Engraft into Tumor Stroma and Produce Potent Antitumor Proteins In Situ.

Michael Andreeff, MD, PhD, Jennifer Dembinski, Brett M. Hall, Ph.D., Matus Studeny, M.D., Xiaoyang Ling, Ph.D., Maria Cabreira-Hansen, Ph.D., A. Kate Sasser, Teresa McQueen, Frederick Lang, M.D., Frank C. Marini, Ph.D.

Blood (2006) 108 (11): 352.

https://doi.org/10.1182/blood.V108.11.352.352

Published: 2006

Journal Articles

BLIMP-1 Is a Target of Cellular Stress and Downstream of the Unfolded Protein Response.

Gina Doody, PhD, Sophie Stephenson, Msc, Reuben Tooze, MBBS, PhD

Blood (2005) 106 (11): 2207.

https://doi.org/10.1182/blood.V106.11.2207.2207

Published: 2005

Journal Articles

Developing Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome.

Marguerite V. Evans-Galea, PhD, Matthew M. Wielgosz, PhD, Ted S. Strom, MD/PhD, Hideki Hanawa, MD/PhD, John M. Cunningham, MD, Arthur W. Nienhuis, MD

Blood (2004) 104 (11): 3170.

https://doi.org/10.1182/blood.V104.11.3170.3170

Published: 2004

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Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

The Immunomodulatory Drugs, through Loss of Ikaros and Aiolos, Derepress CD38 and Functionally Synergise with Daratumumab

Inhibition of CDK4/CDK6 Sensitizes Myeloma to IMiD By Reducing the MEIS2 to Cereblon Ratio That Accelerates IKZF1 and IKZF3 Degradation

No Development of Neutralizing Antibodies Against Recombinant Interferon-Alpha in Ph-Negative Myeloproliferative Neoplasms - a Prospective Study

Surface Ifitms on Megakaryocytes and Platelets Regulate Fibrinogen Endocytosis Under Inflammatory Conditions

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Age-Associated Bone Disease in Factor VIII-Deficient Mice

IAP Antagonists Are a Novel Class Of Immunomodulators That Induce Complete Response In Vk*MYC Myeloma By Stimulating Plasmacytoid Dendritic Cells To Secrete IFNa

Negative Regulation of Eosinophil Production by Toll-Like Receptors

Synergistic Loss of IRF4 and Induction of IRF7 Sensitizes Primary Myeloma Cells to IMiD Killing by IFNβ in Prolonged Early G1 Arrest Induced by CDK4/CDK6 Inhibition

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Episomal Anchorage Maintains Non-Integrating Lentiviral Vectors in Dividing Cells

Clopidogrel, a P2Y12 Receptor Antagonist, Potentiates the Inflammatory Response in a Rat Model of Peptidoglycan Polysaccharide - Induced Arthritis,

Upregulation of hGC-1 Expression by Hypomethylation, Retinoic Acid and Interferons in Human Myeloid Leukemia

Regulation of TLR Expression and Activation in Human Mesenchymal Stromal Cells by IFN-a, IFN-g and TNF-a.

Mesenchymal Stem Cells Selectively Engraft into Tumor Stroma and Produce Potent Antitumor Proteins In Situ.

BLIMP-1 Is a Target of Cellular Stress and Downstream of the Unfolded Protein Response.

Developing Lentiviral Vectors for Gene Therapy of Wiskott-Aldrich Syndrome.

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