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Journal Articles

Proteomic Profiling and Mechanistic Investigating of a Novel Anti-Cancer Small Molecule Inhibitor of Sec61

Yu Qian, PhD, Henry W.B. Johnson, PhD, Christopher J. Kirk, PhD, Eric Lowe, BS, Dustin McMinn, PhD, Beatriz Millare, BS, Tony Muchamuel, MS, Jinhai Wang, PhD

Blood (2019) 134 (Supplement_1): 2076.

https://doi.org/10.1182/blood-2019-125988

Published: 2019

Journal Articles

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, Zhaojin Yu, Paulina Siejka-Zielinska, Zhenhua Chen, PhD, Emily Prince, Chao Shen, PhD, Zejuan Li, MD, Chunxiao Song, Yingming Zhao, Jianjun Chen, PhD

Blood (2019) 134 (Supplement_1): 1249.

https://doi.org/10.1182/blood-2019-127321

Published: 2019

Journal Articles

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

Lauren M Brown, BSc, Hannah Huckstep, BSc, Jarrod Sandow, PhD, Ray C Bartolo, PhD, Nadia Davidson, PhD, Breon Schmidt, BSc, Stefan Bjelosevic, BSc, Ricky W Johnstone, PhD, Alicia Oshlack, PhD, Melissa Davis, PhD, Paul G Ekert

Blood (2018) 132 (Supplement 1): 2628.

https://doi.org/10.1182/blood-2018-99-117844

Published: 2018

Journal Articles

NSD2 Interacts with SMARCA2 and Regulates Expression of Oncogenes CCND1 and PRL3 in T(4;14) Multiple Myeloma

Jing Yuan Chooi, BSc, Zhigang Xie, PhD, Jayantha Gunaratne, PhD, Dennis Keppei, PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS

Blood (2018) 132 (Supplement 1): 4479.

https://doi.org/10.1182/blood-2018-99-110671

Published: 2018

Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD

Blood (2018) 132 (Supplement 1): 4674.

https://doi.org/10.1182/blood-2018-99-110967

Published: 2018

Journal Articles

A Direct Comparison of the In Vivo Efficacy and in Vitro Signaling of Chimeric Antigen Receptors and Endogenous T Cell Receptors

Mark Eric Kohler, MD, PhD, Yinmeng Yang, PhD, Gian Sepulveda, Terry J. Fry, MD

Blood (2017) 130 (Supplement 1): 4451.

https://doi.org/10.1182/blood.V130.Suppl_1.4451.4451

Published: 2017

Journal Articles

Characterization of Metabolic Response to AG-348, an Allosteric Activator of Red Cell Pyruvate Kinase, in Healthy Volunteers and Pyruvate Kinase Deficiency Patients

Victor Chubukov, Kendall Johnson, Penelope A Kosinski, Michelle Clasquin, Abhishek Jha, Hyeryun Kim, Thomas P Roddy, Elizabeth Merica, Ann J Barbier, Lenny Dang, Lee Silverman, Charles Kung

Blood (2016) 128 (22): 2452.

https://doi.org/10.1182/blood.V128.22.2452.2452

Published: 2016

Journal Articles

Comprehensive Analysis of the Structural, Biochemical and Signaling Differences of the p210 and p185 Isoforms of Bcr-Abl in CML and B-ALL

Oliver Hantschel, PhD, Sina Reckel, Hamelin Romain, Florence Armand, Delphine Harduin, Shohei Koide, Volker Dötsch, Marc Moniatte

Blood (2016) 128 (22): 4238.

https://doi.org/10.1182/blood.V128.22.4238.4238

Published: 2016

Journal Articles

Alloreactive Natural Killer Cells Initiate a Unique Cellular and Molecular Pathway That Greatly Accelerates Immune Reconstitution after Allogeneic Bone Marrow Transplantation

Loredana Ruggeri, Elena Urbani, Davide Chiasserini, Federica Susta, Pierluigi Orvietani, Emanuela Burchielli, Dunia Ramarli, Luciano Binaglia, Connie Jimenez, Georg A. Hollander, Andrea Velardi

Blood (2016) 128 (22): 548.

https://doi.org/10.1182/blood.V128.22.548.548

Published: 2016

Journal Articles

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Blood (2016) 128 (22): 2687.

https://doi.org/10.1182/blood.V128.22.2687.2687

Published: 2016

Journal Articles

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

Julio Lahoz-Beneytez, Marjet Elemans, Yan Zhang, Raya Ahmed, Arafa Salam, Michael Block, Christoph Niederalt, Becca Asquith, Derek Macallan

Blood (2016) 127 (26): 3431–3438.

https://doi.org/10.1182/blood-2016-03-700336

Published: 2016

Includes: Supplemental data

Journal Articles

Differential ICAM3 Gene Expression Correlates with Susceptibility to Natural Killer Cell-Mediated Lysis in Multiple Myeloma

Tarun K. Garg, PhD, Ricky D Edmondson, PhD, Shweta S. Chavan, PhD, Katie Stone, BS, Justin M Stivers, Jessica I Warden, Veronica Macleod, Charles M Skinner, Joshuah D Lingo, Amy D Greenway, Junaid Khan, Donald Johann, MD MS, Christoph Heuck, MD, Bart Barlogie, MD PhD, Gareth J Morgan, MDPhD, Joshua Epstein, DSc, Frits van Rhee, MD PhD

Blood (2015) 126 (23): 2990.

https://doi.org/10.1182/blood.V126.23.2990.2990

Published: 2015

Journal Articles

Combination Therapy of Selinexor with Bortezomib or Carfilzomib Overcomes Drug Resistance to Proteasome Inhibitors (PI) in Human Multiple Myeloma

Daniel M Sullivan, MD, Trinayan Kashyap, MS, Jana L Dawson, BS, Yosef Landesman, PhD, Steven Grant, MD, Kenneth H. Shain, MD PhD, Yun Dai, PhD, Michael Kauffman, MD PhD, Sharon Shacham, Joel G Turner, PhD

Blood (2015) 126 (23): 3048.

https://doi.org/10.1182/blood.V126.23.3048.3048

Published: 2015

Journal Articles

Identification of Biomarkers Associated with MAF-Mediated Resistance to Proteasome Inhibitors in t(14;16) Multiple Myeloma

Ya-Wei Qiang, Shiqiao Ye, PhD BSc, MSc, Ricky D Edmondson, PhD, Yuhua Huang, Sarah K. Johnson, PhD, Caleb K. Stein, MS, Bart Barlogie, MD PhD, Joshua Epstein, DSc, Gareth J Morgan, MDPhD, Faith E Davies, MD

Blood (2015) 126 (23): 3020.

https://doi.org/10.1182/blood.V126.23.3020.3020

Published: 2015

Journal Articles

Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation

Eelke Béguin, Bart van den Eshof, Koen Mertens, PhD, Alexander Meijer, PhD, Maartje van den Biggelaar

Blood (2015) 126 (23): 1039.

https://doi.org/10.1182/blood.V126.23.1039.1039

Published: 2015

Journal Articles

Towards a Targeted Therapy:Phosphoproteomics Reveals Signaling Pathways That Are Normalized in AML Cells Following Treatment with Anti-CD44 Antibodies

Heba M. Jalal El-Din, Jasmeen S. Merzaban, PhD

Blood (2015) 126 (23): 1402.

https://doi.org/10.1182/blood.V126.23.1402.1402

Published: 2015

Journal Articles

Differential Signaling through p190 and p210 Forms of BCR-ABL Fusion Proteins Revealed By Proteomic Analysis

Jevon Cutler, Rahia Tahir, Jingnan Han, Raja Sekhar Nirujogi, Tai-Chung Huang, MD, Xianrong Wong, Saradhi Mallampati, Xiaoping Sun, MD PhD, Patrick Brown, MD, Karen Reddy, PhD, Akhilesh Pandey, MD PhD

Blood (2015) 126 (23): 3651.

https://doi.org/10.1182/blood.V126.23.3651.3651

Published: 2015

Journal Articles

Uncover TET1 Targets in MLL -Rearranged Leukemia

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, PhD, Okwang Kwon, Ping Chen, Xi Jiang, PhD, Chao Hu, Hao Huang, PhD, Yungui Wang, PhD, Xi Qin, Stephen Arnovitz, Shenglai Li, Jennifer Strong, Rui Su, PhD, Mary Beth Neilly, Zejuan Li, MD PhD, Yingming Zhao, Jianjun Chen, PhD

Blood (2015) 126 (23): 3632.

https://doi.org/10.1182/blood.V126.23.3632.3632

Published: 2015

Journal Articles

PRL-3 Mediates Survival of Primary Myeloma Cells

Torstein Baade Rø, MD PhD, Tobias Schmidt Slordahl, MD PhD, Pegah Abdollahi, MSc, Esten Vansemb, Lars Hagen, PhD, Katarzyna Anna Baranowska, MD, Kristine Misund, PhD, Geir Slupphaug, PhD, Magne Borset, MD PhD

Blood (2014) 124 (21): 2040.

https://doi.org/10.1182/blood.V124.21.2040.2040

Published: 2014

Journal Articles

Myc Commands an Aurora Kinase – Sumoylation Circuit Required for B Cell Lymphoma Growth and Survival

Alexander Hoellein, MD, Stephanie Schoeffmann, Fallahi Mohammad, PhD, John L Cleveland, PhD, Johannes Gloeckner, PhD, Marius Ueffing, PhD, Martina Rudelius, MD, Christian Peschel, MD, Ulrich Keller, MD

Blood (2014) 124 (21): 3107.

https://doi.org/10.1182/blood.V124.21.3107.3107

Published: 2014

NARROW

Proteomic Profiling and Mechanistic Investigating of a Novel Anti-Cancer Small Molecule Inhibitor of Sec61

TET1 Modulates DNA Replication in Leukemia Cells Via a Catalytic-Independent Mechanism through Cooperating with KAT8

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

NSD2 Interacts with SMARCA2 and Regulates Expression of Oncogenes CCND1 and PRL3 in T(4;14) Multiple Myeloma

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

A Direct Comparison of the In Vivo Efficacy and in Vitro Signaling of Chimeric Antigen Receptors and Endogenous T Cell Receptors

Characterization of Metabolic Response to AG-348, an Allosteric Activator of Red Cell Pyruvate Kinase, in Healthy Volunteers and Pyruvate Kinase Deficiency Patients

Comprehensive Analysis of the Structural, Biochemical and Signaling Differences of the p210 and p185 Isoforms of Bcr-Abl in CML and B-ALL

Alloreactive Natural Killer Cells Initiate a Unique Cellular and Molecular Pathway That Greatly Accelerates Immune Reconstitution after Allogeneic Bone Marrow Transplantation

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

Differential ICAM3 Gene Expression Correlates with Susceptibility to Natural Killer Cell-Mediated Lysis in Multiple Myeloma

Combination Therapy of Selinexor with Bortezomib or Carfilzomib Overcomes Drug Resistance to Proteasome Inhibitors (PI) in Human Multiple Myeloma

Identification of Biomarkers Associated with MAF-Mediated Resistance to Proteasome Inhibitors in t(14;16) Multiple Myeloma

Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation

Towards a Targeted Therapy:Phosphoproteomics Reveals Signaling Pathways That Are Normalized in AML Cells Following Treatment with Anti-CD44 Antibodies

Differential Signaling through p190 and p210 Forms of BCR-ABL Fusion Proteins Revealed By Proteomic Analysis

Uncover TET1 Targets in MLL -Rearranged Leukemia

PRL-3 Mediates Survival of Primary Myeloma Cells

Myc Commands an Aurora Kinase – Sumoylation Circuit Required for B Cell Lymphoma Growth and Survival

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American Society of Hematology

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ASH Publications

American Society of Hematology

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