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Mary Beth Neilly
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Journal Articles

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Hengyou Weng, PhD, Huilin Huang, PhD, Xi Qin, He Huang, PhD, Okwang Kwon, Ping Chen, Xi Jiang, PhD, Chao Hu, PhD, Hao Huang, PhD, Yungui Wang, PhD, Stephen Arnovitz, Shenglai Li, Jennifer Strong, Kyle Ferchen, Rui Su, PhD, Lei Dong, Chenying Li, Mary Beth Neilly, Zejuan Li, MD PhD, Jason Stewart, PhD, Carolyn Price, Yingming Zhao, Jianjun Chen, PhD
Journal: Blood
Blood (2016) 128 (22): 2687.
https://doi.org/10.1182/blood.V128.22.2687.2687
Published: 2016
Journal Articles

Overexpression and Knockout of Mir-126 Both Promote Leukemogenesis through Targeting Distinct Gene Signaling

Rui Su, PhD, Zejuan Li, MD PhD, Ping Chen, Yuanyuan Li, Hu Chao, Yungui Wang, PhD, Stephen Arnovitz, Miao He, Sandeep Gurbuxani, MBBS, PhD, Zhixiang Zuo, Abdel G. Elkahloun, Shenglai Li, Hengyou Weng, PhD, Hao Huang, Mary Beth Neilly, Shusheng Wang, Richard A. Larson, MD, Jiwang Zhang, Xi Jiang, PhD, Minjie Wei, Jie Jin, MD PhD, Paul P. Liu, Jianjun Chen, PhD
Journal: Blood
Blood (2015) 126 (23): 3667.
https://doi.org/10.1182/blood.V126.23.3667.3667
Published: 2015
Journal Articles

Uncover TET1 Targets in MLL -Rearranged Leukemia

Hengyou Weng, PhD, Huilin Huang, PhD, He Huang, PhD, Okwang Kwon, Ping Chen, Xi Jiang, PhD, Chao Hu, Hao Huang, PhD, Yungui Wang, PhD, Xi Qin, Stephen Arnovitz, Shenglai Li, Jennifer Strong, Rui Su, PhD, Mary Beth Neilly, Zejuan Li, MD PhD, Yingming Zhao, Jianjun Chen, PhD
Journal: Blood
Blood (2015) 126 (23): 3632.
https://doi.org/10.1182/blood.V126.23.3632.3632
Published: 2015
Journal Articles

Targeted Treatment of FLT3 -Overexpressing Acute Myeloid Leukemia with MiR-150 Nanoparticles Guided By Conjugated FLT3 Ligand Peptides

Xi Jiang, PhD, Jason Bugno, Chao Hu, Yang Yang, PhD, Tobias Herold, MD, Jun Qi, PhD, Ping Chen, Sandeep Gurbuxani, MBBS, PhD, Stephen Arnovitz, Bryan Ulrich, Hengyou Weng, PhD, Yungui Wang, PhD, Hao Huang, PhD, Shenglai Li, Jennifer Strong, Mary Beth Neilly, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Stefan K. Bohlander, MD, Jie Jin, MD PhD, Zejuan Li, MD PhD, James E. Bradner, MD, Seungpyo Hong, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2015) 126 (23): 3784.
https://doi.org/10.1182/blood.V126.23.3784.3784
Published: 2015
Journal Articles

Overexpression and knockout of miR-126 both promote leukemogenesis

Zejuan Li, Ping Chen, Rui Su, Yuanyuan Li, Chao Hu, Yungui Wang, Stephen Arnovitz, Miao He, Sandeep Gurbuxani, Zhixiang Zuo, Abdel G. Elkahloun, Shenglai Li, Hengyou Weng, Hao Huang, Mary Beth Neilly, Shusheng Wang, Eric N. Olson, Richard A. Larson, Michelle M. Le Beau, Jiwang Zhang, Xi Jiang, Minjie Wei, Jie Jin, Paul P. Liu, Jianjun Chen
Journal: Blood
Blood (2015) 126 (17): 2005–2015.
https://doi.org/10.1182/blood-2015-04-639062
Published: 2015
Includes: Supplemental data
Journal Articles

Polycomb Group Member Rybp Is a Functional Tumor Suppressor Repressed By Mir-9 in MLL-Rearranged AML

Colles Price, Ping Chen, Shenglai Li, Zejuan Li, MD PhD, Yuanyuan Li, Xi Jiang, PhD, Hao Huang, PhD, Hengyou Weng, PhD, Bryan Ulrich, Stephen Arnovitz, Mary Beth Neilly, Jianjun Chen, PhD
Journal: Blood
Blood (2014) 124 (21): 871.
https://doi.org/10.1182/blood.V124.21.871.871
Published: 2014
Journal Articles

MLL-Rearranged Acute Myeloid Leukemias Drive Expression Of Mir-9, a Critical Oncogene In Leukemogenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2013) 122 (21): 3740.
https://doi.org/10.1182/blood.V122.21.3740.3740
Published: 2013
Journal Articles

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-Ming Hong, Rejani B. Kunjamma, Haomin Ren, Chunjiang He, Chong-Zhi Wang, Abdel G. Elkahloun, Peter J. M. Valk, Konstanze Döhner, Mary Beth Neilly, Lars Bullinger, Ruud Delwel, Bob Löwenberg, Paul P. Liu, Richard Morgan, Janet D. Rowley, Chun-Su Yuan, Jianjun Chen
Journal: Blood
Blood (2013) 121 (8): 1422–1431.
https://doi.org/10.1182/blood-2012-07-442004
Published: 2013
Includes: Supplemental data
Journal Articles

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL -Rearranged Acute Leukemia

Zejuan Li, MD, PhD, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, MD, Hao Huang, PhD, Xi Jiang, PhD, Gia-Ming Hong, PhD, Chunjiang He, PhD, Chong-Zhi Wang, Abdel Elkahloun, PhD, Peter J. M. Valk, PhD, Konstanze Dohner, MD, PhD, Mary Beth Neilly, Lars Bullinger, MD, PhD, Ruud Delwel, PhD, Bob Lowenberg, MD, PhD, Pu Paul Liu, MD, PhD, Richard Morgan, Janet D. Rowley, MD, Chun-Su Yuan, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3522.
https://doi.org/10.1182/blood.V120.21.3522.3522
Published: 2012
Journal Articles

Blockade of Mir-150 Maturation by MLL -Fusion/MYC/Lin-28 Is Required for MLL -Associated Leukemia

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Xiao Wang, Sandeep Gurbuxani, MBBS, PhD, Ping Chen, MD, Chunjiang He, PhD, Dewen You, PhD, Shuodan Zhang, Jinhua Wang, Stephen Arnovitz, Abdel Elkahloun, PhD, Colles Price, Gia-Ming Hong, PhD, Haomin Ren, Rejani B. Kunjamma, Mary Beth Neilly, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Robert K. Slany, PhD, Paul P. Liu, MD, PhD, Jun Lu, PhD, Jiwang Zhang, MD, PhD, Chuan He, PhD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3499.
https://doi.org/10.1182/blood.V120.21.3499.3499
Published: 2012
Journal Articles

MLL-Associated Leukemias Drive Expression of MiR-9, Required for Tumorigenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 525.
https://doi.org/10.1182/blood.V120.21.525.525
Published: 2012
Journal Articles

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, Xi Jiang, Ping Chen, Stephen Arnovitz, Michael D. Radmacher, Kati Maharry, Abdel Elkahloun, Xinan Yang, Chunjiang He, Miao He, Zhiyu Zhang, Konstanze Dohner, Mary Beth Neilly, Colles Price, Yves A. Lussier, Yanming Zhang, Richard A. Larson, Michelle M. Le Beau, Michael A. Caligiuri, Lars Bullinger, Peter J. M. Valk, Ruud Delwel, Bob Lowenberg, Paul P. Liu, Guido Marcucci, Clara D. Bloomfield, Janet D. Rowley, Jianjun Chen
Journal: Blood
Blood (2012) 119 (10): 2314–2324.
https://doi.org/10.1182/blood-2011-10-386235
Published: 2012
Includes: Supplemental data
Journal Articles

Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia

Zejuan Li, MD, PhD, Hao Huang, PhD, Yuanyuan Li, Xi Jiang, PhD, Ping Chen, MD, Stephen Arnovitz, Michael D. Radmacher, PhD, Kati Maharry, MAS, Abdel Elkahloun, Xinan Yang, Chunjiang He, PhD, Colles O. Price, Konstanze Dohner, MD, PhD, Zhiyu Zhang, Chen Shen, Mary Beth Neilly, Yves A Lussier, Yanming Zhang, MD, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Michael A Caligiuri, MD, Lars Bullinger, Peter Valk, Ruud Delwel, Ph.D., Bob Lowenberg, MD, PhD, Paul P. Liu, Guido Marcucci, MD, Clara D. Bloomfield, MD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 236.
https://doi.org/10.1182/blood.V118.21.236.236
Published: 2011
Journal Articles

MLL-Rearrangements Result in Upregulation of Mir-9 and Subsequent Inhibition of the Tumor Suppressor TGFBI

Colles O. Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 2453.
https://doi.org/10.1182/blood.V118.21.2453.2453
Published: 2011
Journal Articles

Repression of Mir-495, a Microrna Associated with Favorable Outcome of Acute Myeloid Leukemia Patients, Is Required for the MLL -Associated Leukemogenesis,

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Ping Chen, MD, Chunjiang He, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 3462.
https://doi.org/10.1182/blood.V118.21.3462.3462
Published: 2011
Journal Articles

Identification of Genes Deregulated in Both Human and Murine MLLRearrangement Leukemias.

Zejuan Li, MD, PhD, Roger T. Luo, Shuangli Mi, Miao Sun, Ping Chen, Mary Beth Neilly, Yanming Zhang, Janet D. Rowley, Michael J. Thirman, Jianjun Chen
Journal: Blood
Blood (2008) 112 (11): 3359.
https://doi.org/10.1182/blood.V112.11.3359.3359
Published: 2008
Journal Articles

MicroRNA Expression Signatures Accurately Discriminate Acute Lymphoblastic Leukemia from Acute Myeloid Leukemia.

Shuangli Mi, PhD, Jun Lu, Ph.D., Miao Sun, M.S., Zejuan Li, Ph.D., Hao Zhang, M.S., Mary Beth Neilly, M.S., Yungui Wang, Ph.D., Zhijian Qian, Ph.D., Jie Jin, M.D., Yanming Zhang, M.D., Stefan K. Bohlander, M.D., Michelle M. Le, B.A., Richard Larson, M.D., Todd R. Golub, M.D., Janet D. Rowley, M.D., Jianjun Chen, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 231.
https://doi.org/10.1182/blood.V110.11.231.231
Published: 2007
Journal Articles

MicroRNA Expression Profiles in Acute Myeloid Leukemia with Common Translocations.

Zejuan Li, MD, PhD, Jun Lu, PhD, Miao Sun, MS, Shuangli Mi, PhD, Hao Zhang, MS, Roger T. Luo, PhD, Zhijian Qian, PhD, Mary Beth Neilly, MS, Yungui Wang, PhD, Jie Jin, MD, Yanming Zhang, MD, Stefan K. Bohlander, MD, Richard Larson, MD, Michelle LeBeau, PhD, Michael J. Thirman, MD, Todd R. Golub, MD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2007) 110 (11): 3181.
https://doi.org/10.1182/blood.V110.11.3181.3181
Published: 2007
Journal Articles

Identification of Genes Abnormally Expressed in Human MLL-AF4 Leukemia.

Shuangli Mi, PhD, Miao Sun, M.S., Zejuan Li, M.D., Ph.D., Roger T. Luo, Ph.D., Nimanthi Jayathilaka, B.S., Mary Beth Neilly, M.S., Masha Kocherginsky, Ph.D., Yanming Zhang, M.D. Ph.D., Sanggyu Lee, Ph.D., Theodore G. Karrison, Ph.D., Michael J. Thirman, M.D., San Ming Wang, Ph.D., Janet D. Rowley, M.D., Jianjun Chen, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 4314.
https://doi.org/10.1182/blood.V108.11.4314.4314
Published: 2006
Journal Articles

Gene Expression Profiles in Acute Myeloid Leukemia (AML): From Diagnosis to Prognosis.

Sanggyu Lee, Jianjun Chen, Goulin Zhou, Run Shi, Masha Kocherginsky, Theodore G. Karrison, Yeong Cheol Kim, Xijin Ge, Nimanthi Jayathilaka, Mary Beth Neilly, Gerard Bouffard, Alice Young, Steven Kornblau, Clara Bloomfield, Stefan Bohlander, Pu Paul Liu, Miao Sun, San Ming Wang, Janet D. Rowley
Journal: Blood
Blood (2005) 106 (11): 2996.
https://doi.org/10.1182/blood.V106.11.2996.2996
Published: 2005