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Journal Articles

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Xi Jiang, PhD, Chao Hu, Kyle Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, PhD, Liting Cheng, Zhixiang Zuo, PhD, William Seibel, PhD, Chunjiang He, PhD, Yixuan Tang, Jennifer R Skibbe, Mark Wunderlich, MS, William C Reinhold, Lei Dong, PhD, Chao Shen, PhD, Stephen Arnovitz, Bryan Ulrich, Jiuwei Lu, PhD, Hengyou Weng, PhD, Rui Su, PhD, Huilin Huang, PhD, Yungui Wang, PhD, Chenying Li, MD, Xi Qin, James C. Mulloy, PhD, Yi Zheng, PhD, Jiajie Diao, PhD, Jie Jin, Chong Li, PhD, Paul P Liu, MD, Chuan He, PhD, Yuan Chen, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 857.
https://doi.org/10.1182/blood.V130.Suppl_1.857.857
Published: 2017
Journal Articles

MLL-Rearranged Acute Myeloid Leukemias Drive Expression Of Mir-9, a Critical Oncogene In Leukemogenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2013) 122 (21): 3740.
https://doi.org/10.1182/blood.V122.21.3740.3740
Published: 2013
Journal Articles

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-Ming Hong, Rejani B. Kunjamma, Haomin Ren, Chunjiang He, Chong-Zhi Wang, Abdel G. Elkahloun, Peter J. M. Valk, Konstanze Döhner, Mary Beth Neilly, Lars Bullinger, Ruud Delwel, Bob Löwenberg, Paul P. Liu, Richard Morgan, Janet D. Rowley, Chun-Su Yuan, Jianjun Chen
Journal: Blood
Blood (2013) 121 (8): 1422–1431.
https://doi.org/10.1182/blood-2012-07-442004
Published: 2013
Includes: Supplemental data
Journal Articles

The HOXA/PBX3 Pathway Is an Attractive Therapeutic Target in MLL -Rearranged Acute Leukemia

Zejuan Li, MD, PhD, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, MD, Hao Huang, PhD, Xi Jiang, PhD, Gia-Ming Hong, PhD, Chunjiang He, PhD, Chong-Zhi Wang, Abdel Elkahloun, PhD, Peter J. M. Valk, PhD, Konstanze Dohner, MD, PhD, Mary Beth Neilly, Lars Bullinger, MD, PhD, Ruud Delwel, PhD, Bob Lowenberg, MD, PhD, Pu Paul Liu, MD, PhD, Richard Morgan, Janet D. Rowley, MD, Chun-Su Yuan, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3522.
https://doi.org/10.1182/blood.V120.21.3522.3522
Published: 2012
Journal Articles

Blockade of Mir-150 Maturation by MLL -Fusion/MYC/Lin-28 Is Required for MLL -Associated Leukemia

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Xiao Wang, Sandeep Gurbuxani, MBBS, PhD, Ping Chen, MD, Chunjiang He, PhD, Dewen You, PhD, Shuodan Zhang, Jinhua Wang, Stephen Arnovitz, Abdel Elkahloun, PhD, Colles Price, Gia-Ming Hong, PhD, Haomin Ren, Rejani B. Kunjamma, Mary Beth Neilly, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Robert K. Slany, PhD, Paul P. Liu, MD, PhD, Jun Lu, PhD, Jiwang Zhang, MD, PhD, Chuan He, PhD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 3499.
https://doi.org/10.1182/blood.V120.21.3499.3499
Published: 2012
Journal Articles

MLL-Associated Leukemias Drive Expression of MiR-9, Required for Tumorigenesis

Colles Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Rejani B. Kunjamma, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 525.
https://doi.org/10.1182/blood.V120.21.525.525
Published: 2012
Journal Articles

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

Zejuan Li, Hao Huang, Yuanyuan Li, Xi Jiang, Ping Chen, Stephen Arnovitz, Michael D. Radmacher, Kati Maharry, Abdel Elkahloun, Xinan Yang, Chunjiang He, Miao He, Zhiyu Zhang, Konstanze Dohner, Mary Beth Neilly, Colles Price, Yves A. Lussier, Yanming Zhang, Richard A. Larson, Michelle M. Le Beau, Michael A. Caligiuri, Lars Bullinger, Peter J. M. Valk, Ruud Delwel, Bob Lowenberg, Paul P. Liu, Guido Marcucci, Clara D. Bloomfield, Janet D. Rowley, Jianjun Chen
Journal: Blood
Blood (2012) 119 (10): 2314–2324.
https://doi.org/10.1182/blood-2011-10-386235
Published: 2012
Includes: Supplemental data
Journal Articles

Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia

Zejuan Li, MD, PhD, Hao Huang, PhD, Yuanyuan Li, Xi Jiang, PhD, Ping Chen, MD, Stephen Arnovitz, Michael D. Radmacher, PhD, Kati Maharry, MAS, Abdel Elkahloun, Xinan Yang, Chunjiang He, PhD, Colles O. Price, Konstanze Dohner, MD, PhD, Zhiyu Zhang, Chen Shen, Mary Beth Neilly, Yves A Lussier, Yanming Zhang, MD, Richard A. Larson, MD, Michelle M. Le Beau, PhD, Michael A Caligiuri, MD, Lars Bullinger, Peter Valk, Ruud Delwel, Ph.D., Bob Lowenberg, MD, PhD, Paul P. Liu, Guido Marcucci, MD, Clara D. Bloomfield, MD, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 236.
https://doi.org/10.1182/blood.V118.21.236.236
Published: 2011
Journal Articles

MLL-Rearrangements Result in Upregulation of Mir-9 and Subsequent Inhibition of the Tumor Suppressor TGFBI

Colles O. Price, Ping Chen, MD, Zejuan Li, MD, PhD, Yuanyuan Li, Anissa Wiley, Chunjiang He, PhD, Hao Huang, PhD, Xi Jiang, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 2453.
https://doi.org/10.1182/blood.V118.21.2453.2453
Published: 2011
Journal Articles

Repression of Mir-495, a Microrna Associated with Favorable Outcome of Acute Myeloid Leukemia Patients, Is Required for the MLL -Associated Leukemogenesis,

Xi Jiang, PhD, Hao Huang, PhD, Zejuan Li, MD, PhD, Yuanyuan Li, Ping Chen, MD, Chunjiang He, PhD, Stephen Arnovitz, Mary Beth Neilly, Janet D. Rowley, MD, Jianjun Chen, PhD
Journal: Blood
Blood (2011) 118 (21): 3462.
https://doi.org/10.1182/blood.V118.21.3462.3462
Published: 2011