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Journal Articles

ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Jeff P. Sharman, MD, Versha Banerji, MD, Laura Maria Fogliatto, MD PhD, Yair Herishanu, MD, Talha Munir, MD, Renata Walewska, George Follows, Karin Karlsson, MD, Paolo Ghia, MD PhD, Gillian Corbett, Patricia Walker, MBBS, Miklos Egyed, Wojciech Jurczak, MD PhD, Gilles Salles, MD PhD, Ann Janssens, Florence Cymbalista, MD PhD, William G. Wierda, MD PhD, Steven Coutre, MD, John M. Pagel, MD PhD DSc, Alan Skarbnik, MD, Manali Kamdar, MD, Jennifer Woyach, MD, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Priti Patel, MD, Min Hui Wang, PhD, Sofia Wong, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 31.
https://doi.org/10.1182/blood-2019-128404
Published: 2019
Journal Articles

Persistent Red Blood Cell (RBC) Transfusion Is Associated with Increased Mortality Risk in Transfusion-Dependent (TD) Patients with Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS+)

Rena Buckstein, MD FRCPC, Nancy Zhu, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Lisa Chodirker, MD, Mitchell Sabloff, Grace Cristou, Heather A. Leitch, MD, Eve St. Hilaire, Nicholas Finn, MD, Karen W.L. Yee, MD, Mohamed Elemary, MD, Versha Banerji, MD, Martha Lenis, Aksharh Kirubananthaan, Fei Fei Liu, Derek Tang, PhD BSPharm, Chris Westcott, Vicky Wei-Hsuen Huang, Di Wang, Chris Cameron, Jessica Morison, Paul Spin, Alexandre Mamedov
Journal: Blood
Blood (2019) 134 (Supplement_1): 3012.
https://doi.org/10.1182/blood-2019-123684
Published: 2019
Journal Articles

Intermittent Transfusion Independence Is Associated with Improved Overall Survival in Patients with Transfusion Dependent MDS

Rena Buckstein, MD FRCPC, Lisa Chodirker, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, Thomas J. Nevill, MD, John Storring, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Liying Zhang, PhD, Aksharh Kirubananthaan, Richard A. Wells, MD DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 5416.
https://doi.org/10.1182/blood-2019-129464
Published: 2019
Journal Articles

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Amandeep Singh, MSc, Edwin Nguyen, Aaron Marshall, PhD, James B. Johnston, MD, Spencer Bruce Gibson, PhD, Versha Banerji, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1282.
https://doi.org/10.1182/blood-2019-127562
Published: 2019
Journal Articles

Prognostic Performance of Frailty Measures in MDS Patients Treated with Hypomethylating Agents

Bo Angela Wan, BA, MPhil, Richard A. Wells, MD DPhil, Lisa Chodirker, MD, Ken Rockwood, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD MSc, Mitchell Sabloff, MSc,MDFRCPC, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, John Storring, MD, Thomas J. Nevill, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Martha Lenis, Liying Zhang, PhD, Aksharh Kirubananthaan, Shabbir Alibhai, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 4245.
https://doi.org/10.1182/blood-2019-128949
Published: 2019
Journal Articles

Clinical Characterization of a Novel Mutation in SLC25A38 Resulting in Congenital Sideroblastic Anemia in a Canadian First Nations Population

Kelsey Uminski, MD BSc, Donald S. Houston, MD PhD, Jessica Hartley, MS, CGC, Geoffrey Cuvelier, MD, Sara J. Israels, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1035.
https://doi.org/10.1182/blood-2018-99-110343
Published: 2018
Journal Articles

Mutations in the Phosphoinositide 3-Kinase Pathway (PI3K) Are Associated with Poor Overall Survival (OS) in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP

Joo Y. Song, MD, Anamarija M. Perry, MD, Alex F. Herrera, MD, Pam Skrabek, MD, Michel Nasr, MD, Rebecca Ottesen, Janet Nikowitz, Victoria Bedell, Joyce Murata-Collins, PhD, Yuan Yuan Chen, Yuping Li, PhD, Carlos Gomez Luna, Christine McCarthy, Raju Pillai, MD, Jinhui Wang, Xiwei Wu, PhD, Jasmine M. Zain, MD, Auayporn P. Nademanee, MDBS, Joyce Niland, PhD, Qiang Gong, PhD, Wing C Chan, MD, Dennis D. Weisenburger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2740.
https://doi.org/10.1182/blood.V130.Suppl_1.2740.2740
Published: 2017
Journal Articles

Bendamustine and Rituximab As Initial Therapy in Indolent Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma in a Canadian Population; Highly Effective with Frequent Infections

Lin Yang, Roopesh R. Kansara, MD, Pascal Lambert, MSc, Pam Skrabek, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2780.
https://doi.org/10.1182/blood.V130.Suppl_1.2780.2780
Published: 2017
Journal Articles

Revelance of Gammaglobulin Levels at Diagnosis and during Disease Course in Chronic Lymphocytic Leukemia

Erin Streu, RN MN CON(C), Jayce Bi, Mandy DeSousa, Versha Banerji, MD FRCP, Dhali H.S. Dhaliwal, MD FRCP, Sara Beiggi, PhD, James B. Johnston, MD FRCP
Journal: Blood
Blood (2016) 128 (22): 5561.
https://doi.org/10.1182/blood.V128.22.5561.5561
Published: 2016
Journal Articles

The Efficacy and Cost Effectiveness of Subcutaneous Immunoglobulin (SCIG) Replacement in Patients with Immune Deficiency Secondary to Chronic Lymphocytic Leukemia

Erin Streu, RN MN CON(C), Versha Banerji, MD FRCP, Dhali H.S. Dhaliwal, MD FRCP
Journal: Blood
Blood (2016) 128 (22): 4778.
https://doi.org/10.1182/blood.V128.22.4778.4778
Published: 2016
Journal Articles

Incidence and Implications of Skin Cancers in Cancercare Manitoba Chronic Lymphocytic Leukemia (CLL) Clinic Patients

Sara Beiggi, PhD, Mohammad Pannu, Versha Banerji, MD FRCP, Dhali H.S. Dhaliwal, MD FRCP, Spencer B. Gibson, PhD, Marni Wiseman, MD FRCP, James B. Johnston, MD FRCP
Journal: Blood
Blood (2016) 128 (22): 4359.
https://doi.org/10.1182/blood.V128.22.4359.4359
Published: 2016
Journal Articles

Intergraft Variability in Nonhematopoietic Immunoregulatory Cell Number and Expression of Immune Checkpoint Inhibitor Receptors and Ligands in Both Allo- and Autografts: Potential Target for Intervention

Qingdong Guan, MD PhD, Scott Gilpin, James Doerksen, Lauren Bath, Tracey Lam, Kristjan Paulson, FRCPC, Pascal Lambert, Yun Li, Donna A. Wall, MD
Journal: Blood
Blood (2016) 128 (22): 3382.
https://doi.org/10.1182/blood.V128.22.3382.3382
Published: 2016
Journal Articles

Acquired Hemophilia: A Ten Year Population-Based Review of Incidence Rate, Patient Demographics, and Treatment Outcomes in Manitoba, Canada

Brittany Perija, Donald S Houston, MD PhD, Rami Kotb, MD FRCPC., Sara J. Israels, MD, Emily K. Rimmer, MDFRCPC, Ryan Zarychanski, MD MSc
Journal: Blood
Blood (2016) 128 (22): 3783.
https://doi.org/10.1182/blood.V128.22.3783.3783
Published: 2016
Journal Articles

Time to Diagnosis and Treatment of Lymphoma: A Canadian Population Based Study

Pamela Skrabek, FRCPC, Oliver Bucher, MSc, Matthew D. Seftel, MBChB, FRCP(C), MRCP, Donna Turner, PhD
Journal: Blood
Blood (2015) 126 (23): 2098.
https://doi.org/10.1182/blood.V126.23.2098.2098
Published: 2015
Journal Articles

Clinical Impact of Telomere Shortening in Normal and Leukemia Cells in Chronic Lymphocytic Leukemia

Lin Yang, MD PhD, Sara Beiggi, PhD, Yunli Zhang, Robert Schmidt, Spencer B Gibson, PhD, James B. Johnston, MD
Journal: Blood
Blood (2014) 124 (21): 5641.
https://doi.org/10.1182/blood.V124.21.5641.5641
Published: 2014
Journal Articles

Effectiveness and Cost of Rituximab for CLL in the Province of Manitoba Prior to Its Approval As Part of First Line Treatment

Pamela Skrabek, FRCPC, Rajat Kumar, FRCPC, James B Johnston, MD, Joseph Baptiste, MD, Bernie Lozar, Scott Streilein, Venetia Bourrier, FCSHP, Sri Navaratnam, FRCPC
Journal: Blood
Blood (2012) 120 (21): 4701.
https://doi.org/10.1182/blood.V120.21.4701.4701
Published: 2012
Journal Articles

The Valproic Acid-Fludarabine Combination Induces a Synergistic Response in Chronic Lymphocytic Leukemia Via a Mechanism Involving the Lysosomal Protease Cathepsin B.

Ju-Yoon Yoon, David Szwajcer, MD, FRCPC, Ganchimeg Ishdorj, PhD, Pat Benjaminson, RN, CON(C), James B Johnston, MD, Spencer B Gibson, PhD
Journal: Blood
Blood (2012) 120 (21): 2892.
https://doi.org/10.1182/blood.V120.21.2892.2892
Published: 2012
Journal Articles

Outcome of Patients with Newly Diagnosed Diffuse Large B-Cell Non-Hodgkin Lymphomas (DLBCL) Receiving Initial Therapy in Hospital Compared with An Out-Patient Setting

Morel Rubinger, MD, Seth Shaffer, Yael Shrom, Pascal Lambert, MSc, Ryan Zarychanski, MD, MSc
Journal: Blood
Blood (2011) 118 (21): 4944.
https://doi.org/10.1182/blood.V118.21.4944.4944
Published: 2011
Journal Articles

Population Based Study on the Utilization and Cost of Azacitidine In a Canadian Province.

Pamela Skrabek, FRCPC, Matthew D. Seftel, MRCP, FRCPC, MPH, Donald S Houston, FRCPC, Ph.D, Kristjan Paulson, FRCPC, Pat Burns, Marc Geirnaert, Bernie Lozar, Venetia Bourrier, FCSHP, Sri Navaratnam, FRCPC, Rajat Kumar, FRCPC
Journal: Blood
Blood (2010) 116 (21): 1508.
https://doi.org/10.1182/blood.V116.21.1508.1508
Published: 2010
Journal Articles

Phenotypic Evaluation of a Family Cohort with Hemolytic Anemia

Brett L. Houston, BSc, Donald S. Houston, MD, Ph.D, Sara J. Israels, MD, Gail Coghlan, Bernie N. Chodirker, MD, Teresa Zelinski, Ph.D, Ryan Zarychanski, MD, MSc
Journal: Blood
Blood (2010) 116 (21): 3214.
https://doi.org/10.1182/blood.V116.21.3214.3214
Published: 2010