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Journal Articles

Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia

Lili Song, Bo Yu, Yi Yang, Jianwei Liang, Yingwen Zhang, Lixia Ding, Tianyi Wang, Xinyu Wan, Xiaomin Yang, Jingyan Tang, Shengyue Wang, Benshang Li, Yanxin Li, Haizhong Feng

Blood (2021) 137 (9): 1181–1191.

https://doi.org/10.1182/blood.2020005622

Published: 2021

Includes: Supplemental data

Journal Articles

Association of Nucleophosmin-1 (NPM1) Expression with Leucocyte Count, Blast Count, and Gingiva Hypertrophy in Acute Myeloid Leukemia De Novo Patients in General Hospital of Dr M Djamil Padang Indonesia

Irza Wahid, MD PhD, Tubagus Djumhana Atmakusuma, MD PhD

Blood (2019) 134 (Supplement_1): 5171.

https://doi.org/10.1182/blood-2019-125950

Published: 2019

Journal Articles

CD25 (IL2RA) Is a Direct Transcriptional Target of PRDM1 in Activated Human Natural Killer Cells

Burcu Akman, M.S., Deniz Kursun, Tevfik Hatipoglu, Xiaozhou Hu, MD, Wing C Chan, MD, Can Kucuk, PhD

Blood (2018) 132 (Supplement 1): 3724.

https://doi.org/10.1182/blood-2018-99-113460

Published: 2018

Journal Articles

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Elena Masselli, MD, Cecilia Carubbi, PhD, Benedetta Cambò, MD, Giulia Pozzi, MS, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Elena Follini, MD, Luca Pagliaro, MD, Francesco Bonatti, PhD, Antonio Percesepe, MD PhD, Franco Aversa, MD, Marco Vitale, MD

Blood (2017) 130 (Supplement 1): 5286.

https://doi.org/10.1182/blood.V130.Suppl_1.5286.5286

Published: 2017

Journal Articles

Leukemic Transformation of Post-Essential Thrombocythemia Myelofibrosis: A Unique Case Presenting with Double MPL and CALR Mutations

Cédric Cleyrat, PhD, Devon S Chabot-Richards, MD, David T Lynch, MD, Jason Gotlib, MD, Tracy I. George, Bridget S. Wilson, PhD, Mohammad A Vasef, MD, Cecilia Arana-Yi, MD

Blood (2017) 130 (Supplement 1): 4215.

https://doi.org/10.1182/blood.V130.Suppl_1.4215.4215

Published: 2017

Journal Articles

JAK2 V617F Progenitors Utilize Adaptations to Cell-Autonomous and Microenvironment-Dependent Inflammatory Stress in Polycythemia Vera, Likely Exhibiting Barrier Against Rapid Transformation to Myelofibrosis

Jan Stetka, MSc, Pavla Luzna, PhD, Lucie Lanikova, PhD, Pavla Koralkova, MSc, Jan Gursky, PhD, Zdenek Hodny, MD PhD, Jiri Bartek, MD, Vladimir Divoky, PhD

Blood (2017) 130 (Supplement 1): 1667.

https://doi.org/10.1182/blood.V130.Suppl_1.1667.1667

Published: 2017

Journal Articles

Lnk/Sh2b3 Deficiency Restores Hematopoietic Stem Cell Function and Genome Integrity in Fanconi Anemia

Wei Tong, PhD, Joanna Balcerek, PhD, Jing Jiang, PhD, Nicholas Holdreith, MS, Qinqin Jiang, Krasimira A. Rozenova, PhD, Weihua Li, Roger A Greenberg

Blood (2017) 130 (Supplement 1): 1134.

https://doi.org/10.1182/blood.V130.Suppl_1.1134.1134

Published: 2017

Journal Articles

A Druggable TCF4 and BRD4 Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm

Michele Ceribelli, PhD, Priscilla N Kelly, Stefania Pittaluga, MD PhD, Craig J Thomas, PhD, Boris Reizis, PhD, Louis M. Staudt, MD PhD

Blood (2016) 128 (22): 1513.

https://doi.org/10.1182/blood.V128.22.1513.1513

Published: 2016

Journal Articles

Nuclear NFATc1 Causes Development of Fms-like Receptor Tyrosine Kinase 3 Receptor (FLT3) Internal Tandem Duplication Mutation-Positive (FLT3-ITD) Acute Myeloid Leukemia (AML) and Mediates Drug Resistance

Maria A. Solovey, Ying Wang, MD, Stefan Gattenloehner, MD, Elisabeth Hessmann, MD, Stephan Metzelder, MD, Christian Michel, MD, Volker Ellenrieder, MD, Joachim R. Goethert, MD, Andreas Neubauer, Andreas Burchert, MD

Blood (2016) 128 (22): 1722.

https://doi.org/10.1182/blood.V128.22.1722.1722

Published: 2016

Journal Articles

Crispr/Cas9-Mediated ASXL1 knockout in U937 Human Leukemic Cells Perturbs Myeloid Differentiation

Zhijie Wu, MD, Xin Zhao, MD PhD, Lauren G. Banaszak, BS, Keyvan Keyvanfar, BS, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 1529.

https://doi.org/10.1182/blood.V128.22.1529.1529

Published: 2016

Journal Articles

Mutant p53 Enhances the Development and Sustained Growth of MYC-Driven Lymphoma and Exerts a Dominant Negative Effect Preferentially Deregulating Pathways for Metabolism and DNA Repair

Brandon J Aubrey, MBBS, FRACP, FRCPA, Ana Janic, PhD, Yunshun Chen, PhD, Gordon K Smyth, PhD, Andrew J Kueh, PhD, Stephen Wilcox, PhD, Margs S Brennan, Lin Tai, Daniel HD Gray, PhD, Charis Teh, PhD, Ann Lin, Catherine Chang, Lorraine A O'Reilly, PhD, Marco J Herold, PhD, Andreas Strasser, MSc, PhD FAA, Gemma L Kelly, PhD

Blood (2016) 128 (22): 1545.

https://doi.org/10.1182/blood.V128.22.1545.1545

Published: 2016

Journal Articles

LNK (SH2B3) Deficiency Ameliorates Hematopoietic Stem Cell Defects in Fanconi Anemi

Joanna Balcerek, Jing Jiang, PhD, Qinqin Jiang, Kaosheng Lyu, PhD, Roger Greenberg, MD PhD, Wei Tong, PhD

Blood (2016) 128 (22): 2670.

https://doi.org/10.1182/blood.V128.22.2670.2670

Published: 2016

Journal Articles

Comprehensive Analysis of Safety: Rigosertib in 557 Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Guillermo Garcia-Manero, MD, Pierre Fenaux, MD PhD, Aref Al-Kali, MD, Shyamala C. Navada, MD, Maria R. Baer, MD, Azra Raza, MD, Peter Greenberg, MD, Karl-Anton Kreuzer, MD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Gail J. Roboz, Valeria Santini, MD, Uwe Platzbecker, MD, Michael E. Petrone, MD MPH, Bernard Brownstein, MD, Patrick Simon Zbyszewski, MBA, Manoj Maniar, PhD, Lewis R. Silverman, MD

Blood (2016) 128 (22): 2011.

https://doi.org/10.1182/blood.V128.22.2011.2011

Published: 2016

Journal Articles

Whole-Genome Analysis of the Chromatin Structure in Multiple Myeloma

Marta Kulis, Raquel Ordoñez, Nuria Russiñol, Renée Beekman, Núria Verdaguer-Dot, Teresa Ezponda, Arantxa Carrasco, Joost H.A. Martens, Hendrik G. Stunnenberg, Bruno Paiva, PhD, Jesus San Miguel, MDPhD, Elias Campo, Felipe Prosper, MD, Xabier Agirre, PhD, José I. Martin-Subero

Blood (2016) 128 (22): 118.

https://doi.org/10.1182/blood.V128.22.118.118

Published: 2016

Journal Articles

Oncoscore, a Novel, Internet-Based Tool to Assess the Oncogenic Potential of Genes Can Differentiate Between CP-CML and BC-CML Associated Genes, and Between CP-CML Patients with Good and Bad Prognosis

Rocco Piazza, MD PhD, Luca Mologni, PhD, Daniele Ramazzotti, PhD, Roberta Spinelli, MSc, Alessandra Pirola, MSc, Luca De Sano, MSc, Pierangelo Ferrari, Vera Magistroni, PhD, Nitesh Sharma, PhD, Praveen Khandelwal, PhD, Carlo Gambacorti-Passerini, MD

Blood (2016) 128 (22): 3075.

https://doi.org/10.1182/blood.V128.22.3075.3075

Published: 2016

Journal Articles

Characterization of snoRNA Expression in Acute Myeloid Leukemia

Wayne A. Warner, BS, David Spencer, MDPhD, Maria Trissal, BS, Nichole Helton, BS, Timothy J. Ley, MD, Daniel C. Link, MD

Blood (2015) 126 (23): 3649.

https://doi.org/10.1182/blood.V126.23.3649.3649

Published: 2015

Journal Articles

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Kyung-Rok Yu, PhD, Chuanfeng Wu, PhD, Diego Espinoza, Idalia Yabe, Sandhya R. Panch, MD MPH, So Gun Hong, PhD, Samson Jonathan Koelle, BA, Rong Lu, Aylin Bonifacino, Alan Krouse, Mark Metzger, Robert Donahue, VMD, Cynthia E. Dunbar, MD

Blood (2015) 126 (23): 1151.

https://doi.org/10.1182/blood.V126.23.1151.1151

Published: 2015

Journal Articles

Bone Marrow Derived Mesenchymal Stem Cells from Splenic Marginal Zone Lymphoma Patients Exhibit Altered Proliferative Potential and B Lymphocyte Immunomodulatory Properties

Athanasia Kalyva, PhD, Charalampos Pontikoglou, MD PhD, Christina Kalpadakis, MD PhD, Athina Trakaki, Nikitas Zorzos, Maria Velegraki, MD PhD, Grigorios Panteloglou, Kallliopi Alpantaki, MDPhD, Gerasimos A. Pangalis, MD PhD, Helen A Papadaki, MDPhD

Blood (2015) 126 (23): 2396.

https://doi.org/10.1182/blood.V126.23.2396.2396

Published: 2015

Journal Articles

Molecular Evidence of Ongoing Antigen Driven Somatic Hypermutation in the Natural History of Classic and Variant Hairy Cell Leukemia

Evgeny Arons, PhD, Sarah Davies, Katherine Still, Nathan Chai, Katherine Potocka, Hong Zhou, Robert J. Kreitman, MD

Blood (2015) 126 (23): 2648.

https://doi.org/10.1182/blood.V126.23.2648.2648

Published: 2015

Journal Articles

Acquired in Vitro Resistance to Ibrutinib Is Associated with Transcriptional Re-Programming and Sustained Survival Signaling in Waldenströms Macroglobulinemia and Mantle Cell Lymphoma, Independent of BTK Cys 481 Mutation

Kasyapa S. Chitta, PhD, Aneel Paulus, MDMS, Maja Kuranz-Blake, B.S., Sharoon Akhtar, MPhil, Anne J. Novak, PhD, Stephen M. Ansell, MD PhD, Morie A Gertz, MD, Robert A Kyle, MD, Peter Martin, MD, Morton Coleman, MD, Sikander Ailawadhi, MD, Asher Chanan-Khan, MD

Blood (2014) 124 (21): 2250.

https://doi.org/10.1182/blood.V124.21.2250.2250

Published: 2014

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Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia

Association of Nucleophosmin-1 (NPM1) Expression with Leucocyte Count, Blast Count, and Gingiva Hypertrophy in Acute Myeloid Leukemia De Novo Patients in General Hospital of Dr M Djamil Padang Indonesia

CD25 (IL2RA) Is a Direct Transcriptional Target of PRDM1 in Activated Human Natural Killer Cells

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Leukemic Transformation of Post-Essential Thrombocythemia Myelofibrosis: A Unique Case Presenting with Double MPL and CALR Mutations

JAK2 V617F Progenitors Utilize Adaptations to Cell-Autonomous and Microenvironment-Dependent Inflammatory Stress in Polycythemia Vera, Likely Exhibiting Barrier Against Rapid Transformation to Myelofibrosis

Lnk/Sh2b3 Deficiency Restores Hematopoietic Stem Cell Function and Genome Integrity in Fanconi Anemia

A Druggable TCF4 and BRD4 Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm

Nuclear NFATc1 Causes Development of Fms-like Receptor Tyrosine Kinase 3 Receptor (FLT3) Internal Tandem Duplication Mutation-Positive (FLT3-ITD) Acute Myeloid Leukemia (AML) and Mediates Drug Resistance

Crispr/Cas9-Mediated ASXL1 knockout in U937 Human Leukemic Cells Perturbs Myeloid Differentiation

Mutant p53 Enhances the Development and Sustained Growth of MYC-Driven Lymphoma and Exerts a Dominant Negative Effect Preferentially Deregulating Pathways for Metabolism and DNA Repair

LNK (SH2B3) Deficiency Ameliorates Hematopoietic Stem Cell Defects in Fanconi Anemi

Comprehensive Analysis of Safety: Rigosertib in 557 Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Whole-Genome Analysis of the Chromatin Structure in Multiple Myeloma

Oncoscore, a Novel, Internet-Based Tool to Assess the Oncogenic Potential of Genes Can Differentiate Between CP-CML and BC-CML Associated Genes, and Between CP-CML Patients with Good and Bad Prognosis

Characterization of snoRNA Expression in Acute Myeloid Leukemia

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Bone Marrow Derived Mesenchymal Stem Cells from Splenic Marginal Zone Lymphoma Patients Exhibit Altered Proliferative Potential and B Lymphocyte Immunomodulatory Properties

Molecular Evidence of Ongoing Antigen Driven Somatic Hypermutation in the Natural History of Classic and Variant Hairy Cell Leukemia

Acquired in Vitro Resistance to Ibrutinib Is Associated with Transcriptional Re-Programming and Sustained Survival Signaling in Waldenströms Macroglobulinemia and Mantle Cell Lymphoma, Independent of BTK Cys 481 Mutation

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