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Journal Articles

Hypersialylation Protects Multiple Myeloma Cells from NK Cell-Mediated Immunosurveillance and This Can be Overcome By Targeted Desialylation Using a Sialyltransferase Inhibitor

John Daly, MSc, Subhashis Sarkar, PhD, Alessandro Natoni, PhD, Robert Henderson, MB BCh, Dawn Swan, Mattias Carlsten, MD PhD, Michael E O'Dwyer, MD

Blood (2019) 134 (Supplement_1): 138.

https://doi.org/10.1182/blood-2019-126613

Published: 2019

Journal Articles

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Renata Grozovsky, PhD, Cameron Fraser, BS, Karin M. Hoffmeister, MD, Kristopher Sarosiek, PhD, Silvia Giannini, PhD

Blood (2019) 134 (Supplement_1): 1055.

https://doi.org/10.1182/blood-2019-122184

Published: 2019

Journal Articles

Acute Influenza A Virus Infection Affects Cell Cycle and Lineage Output of Hematopoietic Stem Cells

Marcel E G Rommel, Lisa Walz, Dr., Saskia Kohlscheen, Dr., Franziska Schenk, Yvonne Krebs, Kevin Wittwer, M.Sc., Veronika von Messling, Prof. Dr., Ute Modlich, Prof. Dr. Dr.

Blood (2019) 134 (Supplement_1): 2467.

https://doi.org/10.1182/blood-2019-126482

Published: 2019

Journal Articles

Rash in Patients after T-Cell-Depleted Peripheral Blood Stem Cell Transplantation: Eosinophilia and Pruritus Do Not Distinguish Acute Graft-Versus-Host Disease from Drug Rash

Skylar A Klager, MS, Sean M Devlin, PhD, Margaret Hannum, MS, Ann A. Jakubowski, MD PhD, Alina Markova, MD

Blood (2018) 132 (Supplement 1): 4570.

https://doi.org/10.1182/blood-2018-99-110307

Published: 2018

Journal Articles

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Jia Yu, Xuan Yuan, MD MSc, Kang Zhou, Daniel White, Samuel A. Merrill, MD PhD, Robert A. Brodsky, MD

Blood (2018) 132 (Supplement 1): 3748.

https://doi.org/10.1182/blood-2018-99-119445

Published: 2018

Journal Articles

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

Alexander Prete, Alexander Urtula, Renata Grozovsky, PhD

Blood (2018) 132 (Supplement 1): 3730.

https://doi.org/10.1182/blood-2018-99-119303

Published: 2018

Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD

Blood (2018) 132 (Supplement 1): 980.

https://doi.org/10.1182/blood-2018-99-114775

Published: 2018

Journal Articles

Platelet Protein Glycosylation in Immune Thrombocytopenia

Elena Monzón Manzano, Raul Justo Sanz, Stuart M Haslam, BSc PhD, Leow Ke Xuan, Anne Dell, PhD, Teresa Álvarez-Roman, Mónica Martín, María Isabel Rivas Pollmar, Ihosvany Fernandez-Bello, Miguel A. Canales, Victor Jimenez-Yuste, Nora Butta, PhD

Blood (2018) 132 (Supplement 1): 2437.

https://doi.org/10.1182/blood-2018-99-114568

Published: 2018

Journal Articles

Decreased Erythrocyte Binding Capability for Neutrophil Siglec-9 Is a Source of Oxidative Stress in Sickle Cell Disease

Zachary Monroe Kiser, BS, PhD, Greta L Becker, Julia Nguyen, BS, Anel Lizcano, PhD, John D Belcher, PhD, Ajit P. Varki, MBBS, Gregory M. Vercellotti, MD

Blood (2018) 132 (Supplement 1): 3650.

https://doi.org/10.1182/blood-2018-99-113579

Published: 2018

Journal Articles

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

Soracha E. Ward, Jamie M. O’Sullivan, Clive Drakeford, Sonia Aguila, Christopher N. Jondle, Jyotika Sharma, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Paul Smyth, Orla Sheils, Alain Chion, James S. O’Donnell

Blood (2018) 131 (8): 911–916.

https://doi.org/10.1182/blood-2017-06-787853

Published: 2018

Includes: Supplemental data

Journal Articles

Uptake of Influenza Virus By Platelets Occurs Via Phagocytosis

Gerard Jansen, MD PhD, Huizhi Low, PhD, Judith van den Brand, DVM, PhD, Debbie van Riel, PhD, Erhard van der Vries, PhD

Blood (2017) 130 (Supplement 1): 4834.

https://doi.org/10.1182/blood.V130.Suppl_1.4834.4834

Published: 2017

Journal Articles

Interleukin-6 Drives Multiple Myeloma Progression through Upregulating of CD147/Emmprin Expression and Its Sialylation

Yanmeng Wang, Rong Fan, Li Lei, PhD, Aiying Wang, Xiaman Wang, Shen Ying, Hongli Chen, Caoilfhionn Connolly, MD, Kim De Veirman, Aili He, MD, Karin Vanderkerken, PhD, Michael O'Dwyer, MD, Jinsong Hu, PhD

Blood (2017) 130 (Supplement 1): 3037.

https://doi.org/10.1182/blood.V130.Suppl_1.3037.3037

Published: 2017

Journal Articles

Desialylation of Megakaryocytes Diminishes Platelet Production By Disrupting Megakaryocyte Adhesion, Migration and Proplatelet Formation in Chronic Immune Thrombocytopenia

Qian-Ming Wang, Jia-Min Zhang, Xiao-Lu Zhu, Hai-Xia Fu, Meng Lv, Yuan Kong, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Xiao-Hui Zhang

Blood (2016) 128 (22): 165.

https://doi.org/10.1182/blood.V128.22.165.165

Published: 2016

Journal Articles

Platelets Can Phagocytose Influenza Virus Which May Contribute to the Occurrence of Thrombocytopenia during Influenza Infection

A.J. Gerard Jansen, MD PhD, Hui Zhi Low, PhD, Judith van den Brand, PhD, Debbie van Riel, PhD, Albert Osterhaus, PhD, Erhard van der Vries, PhD

Blood (2016) 128 (22): 1358.

https://doi.org/10.1182/blood.V128.22.1358.1358

Published: 2016

Journal Articles

The N-Linked Glycans of ADAMTS13 Are Critical Determinants of Conformation and Proteolytic Activity

Agata Anna Nowak, MSc, PhD, Michael Laffan, MD, Thomas Anthony Jude McKinnon, PhD

Blood (2015) 126 (23): 1043.

https://doi.org/10.1182/blood.V126.23.1043.1043

Published: 2015

Journal Articles

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

June Li, MSc, Dianne Evertdina van der Wal, PhD, Guangheng Zhu, MD, Miao Xu, MSc, MD, Issaka Yougbare, PhD, Li Ma, PhD, Brian Vadasz, BSc, Renata Grozovsky, PhD, Min Ruan, MD, Lingyan Zhu, MD, Qingshu Zeng, MD, Lili Tao, MD, Zhi-min Zhai, MD, Jun Peng, MD, Ming Hou, MD, Valery Leytin, PhD, John J. Freedman, MD, Karin M Hoffmeister, MD, Heyu Ni, MD PhD

Blood (2014) 124 (21): 467.

https://doi.org/10.1182/blood.V124.21.467.467

Published: 2014

Journal Articles

Platelet Desialylation Is Closely Associated with Cytotoxic T Lymphocyte-Mediated Platelet Destruction in Immune Thrombocytopenia

Jihua Qiu, Linlin Shao, Hai Zhou, Xin Wang, Jun Peng, MD, Ming Hou, MD

Blood (2014) 124 (21): 463.

https://doi.org/10.1182/blood.V124.21.463.463

Published: 2014

Journal Articles

The Effect of Age on the Glycosylation of Human Alpha-2-Macroglobulin

Laura S.E. Calvert, Helen M. Atkinson, Leslie R. Berry, Hons. BSc., Anthony K.C. Chan, MBBS, FRCPC, FRCPath

Blood (2014) 124 (21): 2800.

https://doi.org/10.1182/blood.V124.21.2800.2800

Published: 2014

Journal Articles

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

Qian-ming Wang, Xiao-Hui Zhang, MD, PhD, Fei-er Feng, Chen-cong Wang, Wei Han, Huan Chen, Lan-ping Xu, Xiao Jun Huang

Blood (2014) 124 (21): 432.

https://doi.org/10.1182/blood.V124.21.432.432

Published: 2014

Journal Articles

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Renata Grozovsky, PhD, Antonija Jurak Begonja, John H. Hartwig, Prof, Herve Falet, PhD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 2.

https://doi.org/10.1182/blood.V124.21.2.2

Published: 2014

NARROW

Hypersialylation Protects Multiple Myeloma Cells from NK Cell-Mediated Immunosurveillance and This Can be Overcome By Targeted Desialylation Using a Sialyltransferase Inhibitor

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Acute Influenza A Virus Infection Affects Cell Cycle and Lineage Output of Hematopoietic Stem Cells

Rash in Patients after T-Cell-Depleted Peripheral Blood Stem Cell Transplantation: Eosinophilia and Pruritus Do Not Distinguish Acute Graft-Versus-Host Disease from Drug Rash

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Platelet Protein Glycosylation in Immune Thrombocytopenia

Decreased Erythrocyte Binding Capability for Neutrophil Siglec-9 Is a Source of Oxidative Stress in Sickle Cell Disease

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

Uptake of Influenza Virus By Platelets Occurs Via Phagocytosis

Interleukin-6 Drives Multiple Myeloma Progression through Upregulating of CD147/Emmprin Expression and Its Sialylation

Desialylation of Megakaryocytes Diminishes Platelet Production By Disrupting Megakaryocyte Adhesion, Migration and Proplatelet Formation in Chronic Immune Thrombocytopenia

Platelets Can Phagocytose Influenza Virus Which May Contribute to the Occurrence of Thrombocytopenia during Influenza Infection

The N-Linked Glycans of ADAMTS13 Are Critical Determinants of Conformation and Proteolytic Activity

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

Platelet Desialylation Is Closely Associated with Cytotoxic T Lymphocyte-Mediated Platelet Destruction in Immune Thrombocytopenia

The Effect of Age on the Glycosylation of Human Alpha-2-Macroglobulin

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

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American Society of Hematology

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American Society of Hematology

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