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Journal Articles

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Dijiong Wu, Keding Shao, MD, Qihao Zhou, MD, Jie Sun, Ziqi Wang, Fei Yan, Tingting Liu, Xiangping Wu, Baodong Ye, He Huang, MD PhD, Yuhong Zhou

Blood (2018) 132 (Supplement 1): 2646.

https://doi.org/10.1182/blood-2018-99-115699

Published: 2018

Journal Articles

Establishment of the Safe and Efficient CRISPR/Cas9-RNP Based Gene-Correction Platform of ELANE Mutations in iPSCs of Severe Congenital Neutropenia (CN) Patients with No Response to G-CSF and High Risk to Develop Leukemia

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Tessa Skroblyn, Anna Solovjeva, Maksim Klimiankou, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa

Blood (2017) 130 (Supplement 1): 542.

https://doi.org/10.1182/blood.V130.Suppl_1.542.542

Published: 2017

Journal Articles

BAALC Is a Key Mediator of Leukemia Development in Congenital Neutropenia

Benjamin Dannenmann, Maksim Klimiankou, Anna Solovyeva, Azadeh Zahabi, MSc, Perihan Mir, Masoud Nasri, MSc, Regine Bernhard, Christian Lindner, Tatsuya Morishima, MD PhD, Doris Steinemann, PhD, Cornelia Zeidler, Lothar Kanz, Karl Welte, MD PhD, Julia Skokowa

Blood (2017) 130 (Supplement 1): 541.

https://doi.org/10.1182/blood.V130.Suppl_1.541.541

Published: 2017

Journal Articles

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Eva Moravcsik, Melanie Joannides, Edwige Voisset, Eva Wessel Stratford, Bernd B. Zeisig, Jo Morris, Ruth Densham, Chris Palgrave, Gordon Stamp, Emma Nye, Robert K. Hills, Paolo Salomoni, Chi Wai Eric So, PHD, Scott C. Kogan, Ellen Solomon, David Grimwade, MD, PhD

Blood (2013) 122 (21): 3721.

https://doi.org/10.1182/blood.V122.21.3721.3721

Published: 2013

Journal Articles

The Response of FLT3/ITD AML to FLT3 Inhibition: Apoptosis of Peripheral Blood Blasts and Differentiation of Bone Marrow Blasts

Amy Sexauer, Xiaochuan Yang, PhD, Alexander E Perl, MD, Christian Thiede, MD, Michael J. Borowitz, MD, PhD, Mark J. Levis, MD, PhD

Blood (2011) 118 (21): 943.

https://doi.org/10.1182/blood.V118.21.943.943

Published: 2011

Journal Articles

Wogonoside Exerts Anti-Leukemia of AML Cells Via Restricting Phospholipid Scramblase 1 Gene Expression and Promoting Its Translocation Into Nuclear

Yan Chen, Bao-An Chen, MD, PhD, Qing-long Guo

Blood (2011) 118 (21): 4282.

https://doi.org/10.1182/blood.V118.21.4282.4282

Published: 2011

Journal Articles

The SirT1 Inhibitor Tenovin-6 Induces Monocytic Differentiation in APL Cells

Yoshitaka Sunami, Marito Araki, Soji Morishita, Yumi Hironaka, Yoko Edahiro, Norio Komatsu, Akimichi Ohsaka, MD, PhD

Blood (2011) 118 (21): 1542.

https://doi.org/10.1182/blood.V118.21.1542.1542

Published: 2011

Journal Articles

Recombinant Human Soluble Thrombomodulin Enhances the Anti-Fibrinolytic and Anti-Leukemia Effects of All- Trans Retinoic Acid In Acute Promyelocytic Leukemia Cells.

Takayuki Ikezoe, Jing Yang, Chie Nishioka, Mayuka Isaka, Naomi Iwabu, Mizu Sakai, Ayuko Taniguchi, Kazuto Togitani, Goichi Honda, Akihito Yokoyama

Blood (2010) 116 (21): 1079.

https://doi.org/10.1182/blood.V116.21.1079.1079

Published: 2010

Journal Articles

Terminal Differentiation of FLT3/ITD AML Blasts In Patients Treated with the FLT3 Inhibitor AC220

Mark J. Levis, MD, PhD, Amy Sexauer, Trivikram Rajkhowa, Donald Small, MD, PhD, Michael J. Borowitz, MD, PhD

Blood (2010) 116 (21): 660.

https://doi.org/10.1182/blood.V116.21.660.660

Published: 2010

Journal Articles

A Variant Form of Chronic Granulomatous Disease Caused by A Mutation in the Exon 9 of CYBB Gene Revealed by A Burkholderia Cepacia Invasive Infection.

Nizar Mahlaoui, MS, MSc, Carolina Prando, Stephane Blanche, MD, PhD, Alain Fischer, MD, PhD, Jean-Laurent Casanova, MD, PhD, Jacinta Bustamante, MD, PhD

Blood (2009) 114 (22): 3593.

https://doi.org/10.1182/blood.V114.22.3593.3593

Published: 2009

Journal Articles

Blockade of mTOR Signaling Potentiates the Ability of Histone Deacetylase Inhibitor to Induce Growth Arrest and Differentiation of Acute Myelogenous Leukemia Cells.

Chie Nishioka, Takayuki Ikezoe, Yang Jing, H. Phillip Koeffler, MD, Akihito Yokoyama

Blood (2008) 112 (11): 1612.

https://doi.org/10.1182/blood.V112.11.1612.1612

Published: 2008

Journal Articles

Groucho/TLE Corepressors Regulate Myeloid Differentiation and Size of the Stem Cell/Progenitor Population.

Jianfeng Wang, MD, PhD, Farshid Dayyani, MD, PhD, Christopher Brynczka, David A. Sweetser, MD, PhD

Blood (2008) 112 (11): 1396.

https://doi.org/10.1182/blood.V112.11.1396.1396

Published: 2008

Journal Articles

Quantitative Analysis of Gene Expression for Vascular Endothelial Growth Factor and Its Application.

Xia Bai, Jianxin Fu, MD, PhD, Kaiyang Ding, MD, PhD, Jiannong Cen, Zhaoyue Wang, MD, Changgeng Ruan, MD, PhD

Blood (2007) 110 (11): 3912.

https://doi.org/10.1182/blood.V110.11.3912.3912

Published: 2007

Journal Articles

Correction of Human X-Linked Chronic Granulomatous Disease (X-CGD) Following Transduction of X-CGD CD34+ Cells with a Modified RD114-Pseudotyped Simian Immunodeficiency Virus Lentiviral Vector in a NOD/SCID Mouse Xenograft Model.

Nora Naumann, MD, PhD, Suk See De Ravin, MD, PhD, Uimook Choi, PhD, Morvarid Moayeri, MD, PhD, Yasuhiro Ikeda, DVM, PhD, Harry L. Malech, MD

Blood (2006) 108 (11): 3278.

https://doi.org/10.1182/blood.V108.11.3278.3278

Published: 2006

Journal Articles

Characterization of a Hierarchy of Proliferative Ability in AML: Identification of a Role for NR2F6 in the Maintenance of the Undifferentiated State.

Christine V. Ichim, MSc, Harold L. Atkins, MD, PhD, Norman N. Iscove, MD, PhD, Richard A. Wells, MD, DPhil

Blood (2006) 108 (11): 2539.

https://doi.org/10.1182/blood.V108.11.2539.2539

Published: 2006

Journal Articles

Aminopeptidase Inhibitor Bestatin Potentiates the Induced-Differentiation Activity of All- trans -Retinoic Acid in NB4 Cells Possibly through Down-Regulating c-myc Expression.

Mao-fang Lin, MD, Xi-jun Qian, PhD

Blood (2005) 106 (11): 4443.

https://doi.org/10.1182/blood.V106.11.4443.4443

Published: 2005

Journal Articles

Curcumin Enhances Differentiation of All- Trans Retinoic Acid (ATRA)-Sensitive and ATRA-Resistant Acute Promyelocytic (APL) Cells.

Ameet R. Kini, MD, PhD, Moolky Nagabhushan, PhD, Martin S. Tallman, MD, Shantanu Roychowdhury

Blood (2005) 106 (11): 4456.

https://doi.org/10.1182/blood.V106.11.4456.4456

Published: 2005

Journal Articles

Immortalization of Human Umbilical Cord Blood-Derived Hematopoietic Progenitor Cells.

Sergey S. Akimov, Ali Ramezani, Teresa S. Hawley, Robert G. Hawley

Blood (2005) 106 (11): 1712.

https://doi.org/10.1182/blood.V106.11.1712.1712

Published: 2005

Journal Articles

Role for p40 phox in Fcγ-Receptor-Induced NADPH Oxidase Activation.

Chang II Suh, Natalie Stull, Yoshito Fuji, Sergio Grinstein, Michael Yaffe, Simon Atkinson, Mary C. Dinauer

Blood (2004) 104 (11): 653.

https://doi.org/10.1182/blood.V104.11.653.653

Published: 2004

Journal Articles

Lineage switch induced by overexpression of Ets family transcription factor PU.1 in murine erythroleukemia cells

Toshiyuki Yamada, Masaaki Abe, Toshinori Higashi, Hitomi Yamamoto, Fumiko Kihara-Negishi, Takuya Sakurai, Toshikazu Shirai, Tsuneyuki Oikawa

Blood (2001) 97 (8): 2300–2307.

https://doi.org/10.1182/blood.V97.8.2300

Published: 2001

NARROW

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Establishment of the Safe and Efficient CRISPR/Cas9-RNP Based Gene-Correction Platform of ELANE Mutations in iPSCs of Severe Congenital Neutropenia (CN) Patients with No Response to G-CSF and High Risk to Develop Leukemia

BAALC Is a Key Mediator of Leukemia Development in Congenital Neutropenia

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

The Response of FLT3/ITD AML to FLT3 Inhibition: Apoptosis of Peripheral Blood Blasts and Differentiation of Bone Marrow Blasts

Wogonoside Exerts Anti-Leukemia of AML Cells Via Restricting Phospholipid Scramblase 1 Gene Expression and Promoting Its Translocation Into Nuclear

The SirT1 Inhibitor Tenovin-6 Induces Monocytic Differentiation in APL Cells

Recombinant Human Soluble Thrombomodulin Enhances the Anti-Fibrinolytic and Anti-Leukemia Effects of All- Trans Retinoic Acid In Acute Promyelocytic Leukemia Cells.

Terminal Differentiation of FLT3/ITD AML Blasts In Patients Treated with the FLT3 Inhibitor AC220

A Variant Form of Chronic Granulomatous Disease Caused by A Mutation in the Exon 9 of CYBB Gene Revealed by A Burkholderia Cepacia Invasive Infection.

Blockade of mTOR Signaling Potentiates the Ability of Histone Deacetylase Inhibitor to Induce Growth Arrest and Differentiation of Acute Myelogenous Leukemia Cells.

Groucho/TLE Corepressors Regulate Myeloid Differentiation and Size of the Stem Cell/Progenitor Population.

Quantitative Analysis of Gene Expression for Vascular Endothelial Growth Factor and Its Application.

Correction of Human X-Linked Chronic Granulomatous Disease (X-CGD) Following Transduction of X-CGD CD34+ Cells with a Modified RD114-Pseudotyped Simian Immunodeficiency Virus Lentiviral Vector in a NOD/SCID Mouse Xenograft Model.

Characterization of a Hierarchy of Proliferative Ability in AML: Identification of a Role for NR2F6 in the Maintenance of the Undifferentiated State.

Aminopeptidase Inhibitor Bestatin Potentiates the Induced-Differentiation Activity of All- trans -Retinoic Acid in NB4 Cells Possibly through Down-Regulating c-myc Expression.

Curcumin Enhances Differentiation of All- Trans Retinoic Acid (ATRA)-Sensitive and ATRA-Resistant Acute Promyelocytic (APL) Cells.

Immortalization of Human Umbilical Cord Blood-Derived Hematopoietic Progenitor Cells.

Role for p40 phox in Fcγ-Receptor-Induced NADPH Oxidase Activation.

Lineage switch induced by overexpression of Ets family transcription factor PU.1 in murine erythroleukemia cells

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American Society of Hematology

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American Society of Hematology

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