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Journal Articles

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Adam N Goldfarb, MD, Katie Freeman, BA, Alejandro Ariel Gru, MD, Zollie White, III, MS, Lorrie L Delehanty, BS

Blood (2019) 134 (Supplement_1): 2233.

https://doi.org/10.1182/blood-2019-129172

Published: 2019

Journal Articles

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Anna Kaci, PhD, Emilie Adiceam, Melanie Dupont, Marine Garrido, Jeannig Berrou, Hanane Djamai, Andre Baruchel, Mike Burbridge, Claude Gardin, Herve Dombret, MD PhD, Thorsten Braun, MD

Blood (2019) 134 (Supplement_1): 2631.

https://doi.org/10.1182/blood-2019-125641

Published: 2019

Journal Articles

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Qiu-Sha Huang, Jing Xue, Chen-Cong Wang, Ya-Zhen Qin, Lan-Ping Xu, Kaiyan Liu, Xiao-Jun Huang, MD, Xiao-Hui Zhang

Blood (2019) 134 (Supplement_1): 218.

https://doi.org/10.1182/blood-2019-126384

Published: 2019

Journal Articles

Commonly Used Chemotherapy Drugs Differentially Determine Microenvironment-Mediated Protection, Via Mitochondrial Transfer, to B-Precursor Acute Lymphoblastic Leukaemia Cells

Richard J Burt, MBBS, Aditi Dey, PhD, Kenton Cheuk Yan Ng, BSc, Erik Sahai, PhD, Adele K Fielding, MBBS, PhD FRCP, FRCPath

Blood (2018) 132 (Supplement 1): 2690.

https://doi.org/10.1182/blood-2018-99-113370

Published: 2018

Journal Articles

Novel Methods to Quantitate and Identity Dividing Platelets in Culture Conditions

Jaewoo Song, MDPhD, Sue Jung Kim, MD, Tae-Hyun Yoon, PhD, Hyung-Gi Byun, PhD, June-Won Cheong, MDPhD, Yejin Song, MSc, Hyun-Jeong Kim, PhD, Jihye Ha, MD

Blood (2018) 132 (Supplement 1): 1132.

https://doi.org/10.1182/blood-2018-99-118822

Published: 2018

Journal Articles

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

Hee-Don Chae, PhD, Ritika Dutta, BS, Bruce Tiu, Kara L. Davis, DO, Norman J. Lacayo, MD, Kathleen M. Sakamoto, MD PhD

Blood (2017) 130 (Supplement 1): 2530.

https://doi.org/10.1182/blood.V130.Suppl_1.2530.2530

Published: 2017

Journal Articles

Alisertib, an Aurora a Kinase Inhibitor, Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma Cells

Steven I. Park, MD, Carolina P. Lin, MS, Dirk P. Dittmer, PhD, Steven P. Angus, PhD, Greg G. Wang, PhD, Yuri D. Fedoriw, MD, David B. Darr, BS, Daniel P. Roth, BS, Norman E. Sharpless, MD, Blossom Damania, PhD

Blood (2015) 126 (23): 1551.

https://doi.org/10.1182/blood.V126.23.1551.1551

Published: 2015

Journal Articles

ANKHD1 Is Required for S Phase Progression and Histone Gene Transcription in Multiple Myeloma

Anamika Dhyani, PhD, Patricia Favro, Sara T O Saad, MD PhD

Blood (2014) 124 (21): 2002.

https://doi.org/10.1182/blood.V124.21.2002.2002

Published: 2014

Journal Articles

A Rationale to Enhance the Response to Antimitotic Therapy in Acute Myeloid Leukemia

Dominik Schnerch, MD, Julia Felthaus, Monika Engelhardt, Ralph Wäsch, MD

Blood (2012) 120 (21): 1332.

https://doi.org/10.1182/blood.V120.21.1332.1332

Published: 2012

Journal Articles

Molecular Pathways That Determine the Activation State of Macrophages within the Myeloma Niche

Chelsea Hope, Ellen Hebron, Jaehyup Kim, MD, Jeff Jensen, Claire Flanagan, Neehar Bhatia, Catherine Leith, MBBChir, Ioanna Maroulakou, PhD, Constantine S. Mitsiades, MD, PhD, Shigeki Miyamoto, PhD, Natalie Callander, MD, Peiman Hematti, MD, Fotis Asimakopoulos, MBBChir, PhD

Blood (2012) 120 (21): 443.

https://doi.org/10.1182/blood.V120.21.443.443

Published: 2012

Journal Articles

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Metodi V. Stankov, PhD, Kirsten Heitmann, Zhe Li, PhD, Basant Kumar Thakur, PhD, Diana Panayotova-Dimitrova, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Tino Dittrich, Stephan Emmrich, Nora Schweitzer, MD, Martin Leverkus, MD, Dirk Reinhardt, MD, PhD, Stuart H. Orkin, MD, Georg M.N. Behrens, MD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 3614.

https://doi.org/10.1182/blood.V118.21.3614.3614

Published: 2011

Journal Articles

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Antonija Jurak Begonja, PhD, Lilly Nguyen, Joseph E. Italiano, Jr., PhD, Herve Falet, PhD, Karina F. Meiri, PhD, John H. Hartwig, PhD

Blood (2011) 118 (21): 2201.

https://doi.org/10.1182/blood.V118.21.2201.2201

Published: 2011

Journal Articles

The Spindle Checkpoint Protein BubR1 Is Differentially Expressed in the Lymphatic and Myeloid Lineage and Is a Determinator of Response to Spindle Poisons

Dominik Schnerch, MD, Marie Follo, PhD, Andrea Schmidts, Julika Krohs, Julia Felthaus, Monika Engelhardt, MD, Ralph Wäsch

Blood (2011) 118 (21): 1407.

https://doi.org/10.1182/blood.V118.21.1407.1407

Published: 2011

Journal Articles

Analysis of Mitosis In Acute Myeloid Leukemia Using Live-Cell Imaging.

Dominik Schnerch, Julia Felthaus, Lara Mentlein, Monika Engelhardt, Ralph M. Waesch, MD

Blood (2010) 116 (21): 3363.

https://doi.org/10.1182/blood.V116.21.3363.3363

Published: 2010

Journal Articles

G2/M Arrest Sensitizes Chronic Myelogenous Leukemia Cells to TRAIL-Induced Apoptosis

David Devlin, Medical, Student, Eva Szegezdi, Post-Doctoral, Researcher, Paavilainen Tanja, Student, Orsolya Orosz, Student, Michael O'Dwyer, MD, FRCPath, Michael Carty, Senior, Lecturer, Afshin Samali, PhD, Séverine Cruet Hennequart, PhD

Blood (2010) 116 (21): 4465.

https://doi.org/10.1182/blood.V116.21.4465.4465

Published: 2010

Journal Articles

Combined Inhibition of Janus and Aurora Kinases by the Novel Small Molecule Inhibitor AZD1480 Induces Cell Death and Downregulates PD-L1 and PD-L2 Expression In Hodgkin Lymphoma

Enrico Derenzini, MD, Daniela Buglio, MD, PhD, Hiroshi Katayama, PhD, Yuan Ji, PhD, Subrata Sen, PhD, Anas Younes, MD

Blood (2010) 116 (21): 2848.

https://doi.org/10.1182/blood.V116.21.2848.2848

Published: 2010

Journal Articles

USP44 Is Highly Over-Expresed In T-Cell Acute Lymphoblastic Leukemia and Leads to the Development of Chromosome Missegregation and Aneupoloidy

Paul J. Galardy, MD, Ying Zhang, PhD

Blood (2010) 116 (21): 29.

https://doi.org/10.1182/blood.V116.21.29.29

Published: 2010

Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity

Loredana Santo, MD, Teru Hideshima, MD, PhD, Diana Cirstea, MD, Madhavi L Bandi, PhD, Erik A Nelson, PhD, Hiroshi Ikeda, MD, Sonia Vallet, MD, Samantha Pozzi, MD, Kishan Patel, Gullu Gorgun, PhD, Naoya Mimura, MD, Claire Fabre, MD, Yiguo Hu, PhD, Dharminder Chauhan, PhD, Matthew S Squires, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2010) 116 (21): 2994.

https://doi.org/10.1182/blood.V116.21.2994.2994

Published: 2010

Journal Articles

Nocodazole Induces Multiple Myeloma Cell Death and Reduces Tumor Growth through Sequential Microtubular Network Damage and C-Jun N-Terminal Kinase-Mediated Bcl-2 Phosphorylation.

Rentian Feng, PhD, Huihui Ma, Noriyoshi Kurihara, PhD, DDS, Shirong Li, PhD, Judy A Ziegler, Markus Y Mapara, MD, PhD, G. David Roodman, MD, PhD, Suzanne Lentzsch, MD, PhD

Blood (2009) 114 (22): 296.

https://doi.org/10.1182/blood.V114.22.296.296

Published: 2009

Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

Loredana Santo, M.D., Teru Hideshima, MD., Ph.D., Erik A. Nelson, Ph.D, Diana Cirstea, MD, Madhavi Bandi, Ph.D, Hiroshi Ikeda, MD, PhD, Gullu Gorgun, PhD, Sonia Vallet, MD., Samantha Pozzi, MD, Giulia Perrone, MD, Kishan Patel, Yiguo Hu, Ph.D, Matthew S Squires, Murray Yule, Elisabetta Calabrese, MD., Dharminder Chauhan, Ph.D, Nikhil C. Munshi, Kenneth C. Anderson, MD, Noopur Raje, MD.

Blood (2009) 114 (22): 3833.

https://doi.org/10.1182/blood.V114.22.3833.3833

Published: 2009

NARROW

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

ATRA Could Correct the Defective S1P-Mediated Cytoskeletal Reorganization in Proplatelet Formation of ITP

Commonly Used Chemotherapy Drugs Differentially Determine Microenvironment-Mediated Protection, Via Mitochondrial Transfer, to B-Precursor Acute Lymphoblastic Leukaemia Cells

Novel Methods to Quantitate and Identity Dividing Platelets in Culture Conditions

RSK Inhibition Induces Metaphase Arrest and Apoptosis in Acute Myeloid Leukemia Cells

Alisertib, an Aurora a Kinase Inhibitor, Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma Cells

ANKHD1 Is Required for S Phase Progression and Histone Gene Transcription in Multiple Myeloma

A Rationale to Enhance the Response to Antimitotic Therapy in Acute Myeloid Leukemia

Molecular Pathways That Determine the Activation State of Macrophages within the Myeloma Niche

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

The Spindle Checkpoint Protein BubR1 Is Differentially Expressed in the Lymphatic and Myeloid Lineage and Is a Determinator of Response to Spindle Poisons

Analysis of Mitosis In Acute Myeloid Leukemia Using Live-Cell Imaging.

G2/M Arrest Sensitizes Chronic Myelogenous Leukemia Cells to TRAIL-Induced Apoptosis

Combined Inhibition of Janus and Aurora Kinases by the Novel Small Molecule Inhibitor AZD1480 Induces Cell Death and Downregulates PD-L1 and PD-L2 Expression In Hodgkin Lymphoma

USP44 Is Highly Over-Expresed In T-Cell Acute Lymphoblastic Leukemia and Leads to the Development of Chromosome Missegregation and Aneupoloidy

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity

Nocodazole Induces Multiple Myeloma Cell Death and Reduces Tumor Growth through Sequential Microtubular Network Damage and C-Jun N-Terminal Kinase-Mediated Bcl-2 Phosphorylation.

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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