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Andrea Schmidts
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Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Peritransplant CAR-T cells

Andrea Schmidts
Journal: Blood
Blood (2023) 141 (6): 564–566.
https://doi.org/10.1182/blood.2022018584
Published: 2023
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML)

Mark Leick, MD, Irene Scarfò, PhD, Bryan D. Choi, MD PhD, Rebecca Larson, BS, Amanda A Bouffard, Ana Castano, MD, Maria L. Cabral, BS, Andrea Schmidts, MD, Matthew J. Frigault, MD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4443.
https://doi.org/10.1182/blood-2019-127154
Published: 2019
Journal Articles

Engineering an Optimized Trimeric APRIL-Based CAR to Broaden Targetability of Multiple Myeloma

Andrea Schmidts, MD, Maria Ormhoj, MS, Allison O. Taylor, MS, Selena J. Lorrey, BA, Irene Scarfò, PhD, Matthew J. Frigault, MD, Bryan D. Choi, MD PhD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2059.
https://doi.org/10.1182/blood-2018-99-119633
Published: 2018
Journal Articles

The APC/C Coactivator Cdh1 Controls Self-Renewal and Differentiation of Human and Murine HSPCs

Daniel Ewerth, Stefanie Kreutmair, Andrea Schmidts, Marie Follo, PhD, Dagmar Wider, Julia B. Schueler, DVM, PhD, Julia Felthaus, Justus Duyster, MD, Anna Lena Illert, MD, Monika Engelhardt, MD PhD, Wäsch Ralph, MD
Journal: Blood
Blood (2016) 128 (22): 2650.
https://doi.org/10.1182/blood.V128.22.2650.2650
Published: 2016
Journal Articles

Self-Renewal and Differentiation in Hematopoietic Stem and Progenitor Cells Is Controlled By the APC/C Coactivator Cdh1

Daniel Ewerth, Stefanie Kreutmair, Birgit Kügelgen, Dagmar Wider, Julia Felthaus, Julia Schüler, DVM, PhD, Andrea Schmidts, Justus Duyster, MD PhD, Anna Lena Illert, Monika Engelhardt, Ralph Wäsch, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2370.
https://doi.org/10.1182/blood.V126.23.2370.2370
Published: 2015
Journal Articles

APC/C Cdh1 As a Mediator Of Hematopoietic Differentiation, Self-Renewal and Malignant Transformation

Andrea Schmidts, Daniel Ewerth, Dominik Schnerch, MD, Arunas Kvainickas, Dagmar Wider, Birgit Kügelgen, Heike L. Pahl, PhD, Monika Engelhardt, MD, Ralph Wäsch, MD
Journal: Blood
Blood (2013) 122 (21): 3676.
https://doi.org/10.1182/blood.V122.21.3676.3676
Published: 2013
Journal Articles

Dissecting Stem Cell Proliferation and Differentiation In Association With The Central Cell Cycle Regulator APC/C Cdh1 In Vitro and In Vivo

Daniel Ewerth, Andrea Schmidts, Birgit Kuegelgen, Dagmar Wider, Julia Schüler, Monika Engelhardt, MD, Ralph M. Waesch, MD
Journal: Blood
Blood (2013) 122 (21): 2446.
https://doi.org/10.1182/blood.V122.21.2446.2446
Published: 2013
Journal Articles

Dissecting Stem Cell Proliferation and Differentiation in Association with the Central Cell Cycle Regulator APC/C Cdh1

Daniel Ewerth, Andrea Schmidts, Birgit Kuegelgen, Dagmar Wider, Julia Schüler, Monika Engelhardt, Ralph Wäsch, MD
Journal: Blood
Blood (2012) 120 (21): 1236.
https://doi.org/10.1182/blood.V120.21.1236.1236
Published: 2012
Journal Articles

APC/C Cdh1 Regulates Self-Renewal and Differentiation of Hematopoietic Stem Cells

Andrea Schmidts, Daniel Ewerth, Dagmar Wider, Birgit Kuegelgen, Monika Engelhardt, MD, Ralph Waesch, MD
Journal: Blood
Blood (2011) 118 (21): 2379.
https://doi.org/10.1182/blood.V118.21.2379.2379
Published: 2011
Journal Articles

The Spindle Checkpoint Protein BubR1 Is Differentially Expressed in the Lymphatic and Myeloid Lineage and Is a Determinator of Response to Spindle Poisons

Dominik Schnerch, MD, Marie Follo, PhD, Andrea Schmidts, Julika Krohs, Julia Felthaus, Monika Engelhardt, MD, Ralph Wäsch
Journal: Blood
Blood (2011) 118 (21): 1407.
https://doi.org/10.1182/blood.V118.21.1407.1407
Published: 2011
Journal Articles

APC/C-Cdh1 as a Novel Regulator of Hematopoietic Stem Cell Differentiation.

Andrea Schmidts, Dagmar Wider, Julia Felthaus, Manuel Hein, Dominik Schnerch, Monika Engelhardt, Ralph M. Waesch, MD
Journal: Blood
Blood (2010) 116 (21): 1563.
https://doi.org/10.1182/blood.V116.21.1563.1563
Published: 2010
Journal Articles

Downregulation of the Cell-Cycle Regulating Ubiquitin-Ligase APC/C Cdh1 May Contribute to the Differentiation Block of AML1/Eto Positive AML.

Manuel Hein, Dominik Schnerch, Andrea Schmidts, Julia Felthaus, Dagmar Wider, Gabriele Ihorst, Monika Engelhardt, Ralph M. Waesch
Journal: Blood
Blood (2009) 114 (22): 5045.
https://doi.org/10.1182/blood.V114.22.5045.5045
Published: 2009