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Max Jan
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Journal Articles

A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy

William Lin, Ditsa Sarkar, Joanna Y Kim, Nelson H Knudsen, Isabel C Lane, Andi Cheng, Gabriele Kembaun, Tamina Kienka, Jeannie Carreiro, Amanda A Bouffard, Marcela V Maus, Robert T Manguso, Max Jan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4825.
https://doi.org/10.1182/blood-2023-189628
Published: 2023
Journal Articles

Patients with Deleterious Germline Variants in STXBP2 Develop Toxicity after CAR-T Cell Therapy with Axicabtagene Ciloleucel

Mark B. Leick, Seunghun Han, Kathleen M.E. Gallagher, Harrison Silva, Grace Martin, Sabrina Camp, Hoyin Chu, Riaz Gillani, Michael C. Kann, Bryan D. Choi, Rebecca Larson, Merle Phillips, Tamina Kienka, Stefanie R. Bailey, Charlotte Graham, Christopher R. Reilly, Max Jan, Elba Gonzalez, Nora K. Horick, Justin Budka, Simone Filosto, Rhine R. Shen, Eliezer Van Allen, Saud H AlDubayan, Marcela V. Maus
Journal: Blood
Blood (2022) 140 (Supplement 1): 646–647.
https://doi.org/10.1182/blood-2022-166322
Published: 2022
Journal Articles

Clonal Hematopoiesis is Associated with Reduced Risk of Alzheimer's Disease

Hind Bouzid, Julia Belk, Max Jan, Yanyan Qi, Chloé Sarnowski, Sara Wirth, Lisa Ma, Matthew Chrostek, Herra Ahmad, Daniel Nachun, Winnie Yao, Alexa Beiser, Alexander G. Bick, Joshua Bis, Myriam Fornage, W. T. Longstreth, Oscar Lopez, Pradeep Nataranjan, Bruce Psaty, Claudia Satizabal, Joshua Weinstock, Eric Larson, Paul Crane, C. Dirk Keene, Sudha Seshadri, Ansuman T. Satpathy, Thomas Montine, Siddhartha Jaiswal
Journal: Blood
Blood (2021) 138 (Supplement 1): 5.
https://doi.org/10.1182/blood-2021-151064
Published: 2021
Journal Articles

Elevated Enhancer-Oncogene Contacts and Higher Oncogene Expression Levels By Recurrent CTCF inactivating Mutations in T Cell Acute Lymphoblastic Leukemia

Willem K. Smits, Carlo Vermeulen, Rico Hagelaar, Shunsuke Kimura, Eric Vroegindeweij, Jessica G.C.A.M. Buijs-Gladdines, Ellen Van De Geer, Marjon J.A.M. Verstegen, Erik Splinter, Simon V. van Reijmersdal, Arjan Buijs, Niels Galjart, Winfried Van Eyndhoven, Max Jan Van Min, Roland P Kuiper, Patrick Kemmeren, Charles G. Mullighan, Wouter De Laat, Jules P.P. Meijerink
Journal: Blood
Blood (2021) 138 (Supplement 1): 501.
https://doi.org/10.1182/blood-2021-152221
Published: 2021
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

Using an in-Vivo Degron-Based Approach to Interrogate Dependencies of Serially Acquired Mutations - Including DNMT3a-R882 and NPM1c - in Acute Myeloid Leukemia

Andrew A Guirguis, MD PhD, Alexander Tepper, Max Jan, MD PhD, Quinlan Sievers, MD PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-142566
Published: 2020
Journal Articles

Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors

Max Jan, MD PhD, Ana Castano, MD, Amanda Walker, BA, Andrew A Guirguis, MD PhD, Jessica A Gasser, PhD, Amanda A Bouffard, Mikolaj Slabicki, PhD, Alexander Tepper, Daniel E Grinshpun, Taeyoon Kyung, PhD, Quinlan Sievers, MD PhD, Michael E Birnbaum, PhD, Marcela V Maus, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 866.
https://doi.org/10.1182/blood-2019-124210
Published: 2019
Journal Articles

Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs

Adam S. Sperling, Michael Burgess, Hasmik Keshishian, Jessica A. Gasser, Shruti Bhatt, Max Jan, Mikołaj Słabicki, Rob S. Sellar, Emma C. Fink, Peter G. Miller, Brian J. Liddicoat, Quinlan L. Sievers, Rohan Sharma, Dylan N. Adams, Elyse A. Olesinski, Mariateresa Fulciniti, Namrata D. Udeshi, Eric Kuhn, Anthony Letai, Nikhil C. Munshi, Steven A. Carr, Benjamin L. Ebert
Journal: Blood
Blood (2019) 134 (2): 160–170.
https://doi.org/10.1182/blood.2019000789
Published: 2019
Includes: Supplemental data
Journal Articles

Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant

Max Jan, MD PhD, Matt J Leventhal, BA, Elizabeth A Morgan, MD, Jordan Chase Wengrod, MD PhD, Anewsha Nag, PhD, Samantha D Drinan, BS, Bruce M Wollison, MSc, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Natasha Kekre, MDFRCPC, Vincent T. Ho, MD, John Koreth, MBBS, DPhil, Corey S. Cutler, MD MPH, Sarah Nikiforow, MD PhD, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Jerome Ritz, MD PhD, R. Coleman Lindsley, MD, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 817.
https://doi.org/10.1182/blood-2018-99-113911
Published: 2018
Journal Articles

Discovery of a Novel Mechanism of Resistance to Thalidomide Derivatives

Adam S Sperling, MD PhD, Michael Burgess, PhD, Hasmik Keshishian, PhD, Jessica Gasser, PhD, Max Jan, MD PhD, Rohan Sharma, Mariateresa Fulciniti, PhD, Nikhil Munshi, MD, Steven A. Carr, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 949.
https://doi.org/10.1182/blood-2018-99-115110
Published: 2018
Journal Articles

Absence of Evidence Implicating Hematopoietic Stem Cells As Common Progenitors for DLBCL Mutations

Max Jan, MD PhD, Florian Scherer, MD, David M. Kurtz, MD, Aaron M Newman, PhD, Henning Stehr, PhD, Chih Long Liu, PhD, Li Zhou, Cynthia Glover, Ranjana H Advani, MD, Lauren S Maeda, MD, Neel K. Gupta, MD, Ronald Levy, MD, Christian A. Kunder, MD PhD, Isidro Sánchez-García, MD, Maximilian Diehn, MD PhD, Ash A. Alizadeh, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4107.
https://doi.org/10.1182/blood.V128.22.4107.4107
Published: 2016
Journal Articles

CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes

Stephen S. Chung, MD, Wendy W Pang, Ph.D., Gino K. In, MD, Max Jan, PhD, Virginia M. Klimek, M.D., Ari Melnick, MD, Irving L. Weissman, MD, Ravi Majeti, MD, PhD, Christopher Y. Park, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 210.
https://doi.org/10.1182/blood.V120.21.210.210
Published: 2012
Journal Articles

Clonal Evolution of Pre-Leukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

Max Jan, PhD, Thomas M. Snyder, PhD, M. Ryan Corces-Zimmerman, Irving L. Weissman, Stephen R. Quake, PhD, Ravindra Majeti, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4.
https://doi.org/10.1182/blood.V118.21.4.4
Published: 2011
Journal Articles

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts.

Mark P. Chao, BA, Ash A Alizadeh, MD, PhD, Chad Z. Tang, MS, June Helen Myklebust, PhD, Bindu Varghese, PhD, Max Jan, BA, Ronald Levy, MD, Irving L. Weissman, MD, Ravindra Majeti, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2716.
https://doi.org/10.1182/blood.V114.22.2716.2716
Published: 2009