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Journal Articles

Genome Data Allow in silico Pharmacogenetic Studies Using the Genetic Makeup of Both the Individual Patient As Well As the Disease

Manja Meggendorfer, PhD, Wencke Walter, PhD, Stephan Hutter, PhD, Constance Baer, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3360.
https://doi.org/10.1182/blood-2019-126580
Published: 2019
Journal Articles

NUDT15 Variants Confer High Incidence of Secondary Malignancies of ALL in Children

Masanori Yoshida, MD, Kazuhiko Nakabayashi, PhD, Aiko Sato-Otsubo, PhD, Shinichi Tsujimoto, MD PhD, Kaoru Yoshida, MD, Ryota Shirai, MD, Tomoo Osumi, MD, Yuki Yuza, MD PhD, Masatoshi Takagi, MD PhD, Hiroyuki Takahashi, MD PhD, Katsuyoshi Koh, MD, Akitoshi Kinoshita, MD PhD, Moeko Hino, MD, Toshihiko Imamura, MD PhD, Yozo Nakazawa, MD PhD, Okuya Mayuko, MD PhD, Harumi Kakuda, MD PhD, Masashi Sanada, MD, Kimikazu Matsumoto, MD, PhD, Daisuke Tomizawa, MD PhD, Nobutaka Kiyokawa, MD PhD, Akira Ohara, MD PhD, Atsushi Manabe, MD PhD, Kenichiro Hata, MD PhD, Jun J. Yang, PhD, Motohiro Kato, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2751.
https://doi.org/10.1182/blood-2019-125713
Published: 2019
Journal Articles

Pharmacokinetic and Pharmacogenetic Analysis of Bosutinib in Japanese Patients with Chronic-Phase Chronic Myeloid Leukemia

Akiko Mita, MD, Maiko Abumiya, PhD, Saori Takahashi, Ms, Yoshihiro Kameoka, MD PhD, Masatomo Miura, PhD, Naoto Takahashi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4271.
https://doi.org/10.1182/blood-2018-99-111905
Published: 2018
Journal Articles

Busulfan Pharmacogenetics and Drug Exposure in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation

Jai N Patel, PharmD, Issam Hamadeh, BS, Qing Zhang, PhD, Taylor Brown, BS, MS, Nury M Steuerwald, PhD, Alicia Hamilton, Lawrence J Druhan, PhD, Jiaxian He, MS, James T Symanowski, PhD, Mohammed J Hussain, MD, Jigar Trivedi, MSc, PharmD, Michael Richard Grunwald, MD, Nilanjan Ghosh, MD PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3215.
https://doi.org/10.1182/blood.V130.Suppl_1.3215.3215
Published: 2017
Journal Articles

Tacrolimus Pharmacogenetics and Steady State Drug Concentrations in Cancer Patients Undergoing Allogeneic Stem Cell Transplantation

Issam Hamadeh, BS, Qing Zhang, PhD, Nury M Steuerwald, PhD, Alicia Hamilton, Lawrence J Druhan, PhD, Yordanis Diez, PharmD, Stephanie Rusin, PharmD, Yimei Han, James Symanowski, PhD, Jigar Trivedi, MSc, PharmD, Michael Richard Grunwald, MD, Nilanjan Ghosh, MD PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Jai N Patel, PharmD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1939.
https://doi.org/10.1182/blood.V130.Suppl_1.1939.1939
Published: 2017
Journal Articles

Pharmacogenetic Markers of Treatment Response of Imatinib Mesylate in Chronic Myeloid Leukemia Brazilian Patients

Natália M Vieira, Renata Leite, Fabíola Reginato, Marília Zandoná, Tito Vanelli Costa, Laura Fogliatto, MD, Rafael Linden, Marina Venzon Antunes, Arnaud Capron, Pierre Wallemacq, Sandrine Wagner, Vanessa Mattevi, Marcelo Capra, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5458.
https://doi.org/10.1182/blood.V128.22.5458.5458
Published: 2016
Journal Articles

A pharmacogenetic analysis of the Canadian Cancer Trials Group MY.10 clinical trial of maintenance therapy for multiple myeloma

Clinical Trials & Observations
Ming Han, Alli Murugesan, Nizar J. Bahlis, Kevin Song, Darrell White, Christine Chen, Matthew D. Seftel, Kang Howsen-Jan, Donna Reece, Keith Stewart, Yagang Xie, Annette E. Hay, Lois Shepherd, Marina Djurfeldt, Liting Zhu, Ralph M. Meyer, Bingshu E. Chen, Tony Reiman
Journal: Blood
Blood (2016) 128 (5): 732–735.
https://doi.org/10.1182/blood-2016-06-716902
Published: 2016
Includes: Supplemental data
Journal Articles

Role of Genetic Polymorphisms on Response to R-Chopregimen in Diffuse Large B-Cell Lymphoma Patients: An Interim Analysis of a Multicenter Prospective Pharmacogenetic Study

Luigi Rigacci, Gabriele Perrone, Stefania Nobili, Sofia Kovalchuk, Benedetta Puccini, Federica Lancia, Renato Tassi, Marco Brugia, Ida Landini, Lara Mannelli, Gemma Benelli, Cristina Napoli, Emanuele Cencini, Alberto Fabbri, Lorenzo Iovino, Mario Petrini, Silvia Birtolo, Alessandro Melosi, Varesco Martini, Simone Santini, Carla Breschi, Paolo Bernardeschi, Carmelo Bengala, Alberto Bosi, MD, Enrico Mini
Journal: Blood
Blood (2015) 126 (23): 2483.
https://doi.org/10.1182/blood.V126.23.2483.2483
Published: 2015
Journal Articles

Exploring the Significance of TP53, ABCB1 and GST Polymorphisms on Susceptibility and Pharmacogenetics in Argentinian Patients with Chronic Myeloid Leukemia

Natalia Weich, Master in Science, Cristian Ferri, PhD, Elena Beatriz Moiraghi, MD, Raquel Maria Nelida Bengio, MD, Isabel Amanda Giere, PhD M.Sc, Carolina Pavlovsky, MD, Irene Larripa, PhD, Ariela Freya Fundia, PhD
Journal: Blood
Blood (2015) 126 (23): 5134.
https://doi.org/10.1182/blood.V126.23.5134.5134
Published: 2015
Journal Articles

A Pharmacogenetic Study of the NCIC CTG Clinical Trial My.10: Single Nucleotide Polymorphisms, Prognosis, and Predicting Benefit from IMiD® Compound Maintenance Therapy Following Autologous Stem Cell Transplant for Multiple Myeloma

Ming Han, BSc., Alli Murugesan, MSc, PhD, Nizar J Bahlis, MD, Kevin Song, Darrell White, MD MSc, FRCPC, FACP, Christine Chen, MD, Matthew D. Seftel, MBChB, FRCP(C), MRCP, Kang Howsen-Jan, MD, Donna Reece, Keith Stewart, MD, Yagang Xie, MD PhD FCCMG, Annette E Hay, MB ChB, Lois Shepherd, MD, Bingshu E Chen, PhD, Marina Djurfeldt, MSc., Tony Reiman, MD
Journal: Blood
Blood (2015) 126 (23): 2960.
https://doi.org/10.1182/blood.V126.23.2960.2960
Published: 2015
Journal Articles

Integrating Molecular, Epigenetic and Pharmacogenetic Approaches in Managing Imatinib Resistance Among Malaysian Chronic Myeloid Leukemia Patients

Aziz Baba, MDFRCP, Marjanu Hikmah Elias, Anthony Zian Au, Najlaa Maddin, Siti Maziras Makhtar, Gan Siew Hua, PhD, Azlan Husin, MD, Sarina Sulong, PhD, Rosline Hassan, MD, Ravindran Ankathil, PhD
Journal: Blood
Blood (2014) 124 (21): 3150.
https://doi.org/10.1182/blood.V124.21.3150.3150
Published: 2014
Journal Articles

Cereblon ( CRBN) Gene Polymorphisms Predict Clinical Response and Progression-Free Survival in Multiple Myeloma Patients Treated with Lenalidomide: A Pharmacogenetic Study of Immense Consortium

Elzbieta Iskierka-Jazdzewska, MD, Anna Stepien, MSc, Federico Canzian, PhD, Alessandro Martino, PhD, Daniele Campa, PhD, Angelika Stein, Malgorzata Krawczyk-Kulis, MD PhD, Malwina Rybicka, MD PhD, Slawomira Kyrcz-Krzemien, MD PhD, Aleksandra K. Butrym, MD PhD, Grzegorz Mazur, MD PhD, Artur J. Jurczyszyn, MD PhD, Daria Zawirska, MD PhD, Norbert Grzasko, MD PhD, Waldemar Tomczak, MD PhD, Edyta Subocz, MD PhD, Marzena Watek, MD, Marcin Pasiarski, MD PhD, Marcin Rymko, MD PhD, Malgorzata Calbecka, MD PhD, Agnieszka Druzd-Sitek, PhD, Jan Walewski, MD PhD, Marcin Kruszewski, MD PhD, Malgorzata Razny, MD PhD, Jan M Zaucha, MD PhD, Marek Dudzinski, MD PhD, Pawel Gaj, PhD, Krzysztof Warzocha, MD PhD, Krzysztof Jamroziak, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3628.
https://doi.org/10.1182/blood.V124.21.3628.3628
Published: 2014
Journal Articles

Warfarin pharmacogenetics: it matters if you’re black or white

Mia Wadelius
Journal: Blood
Blood (2014) 124 (14): 2171.
https://doi.org/10.1182/blood-2014-08-594119
Published: 2014
Journal Articles

Pharmacogenetic Approaches Identify ANTXR1 As a Potential Mediator of Response to Therapeutic NF-κB Inhibition in Diffuse Large B Cell Lymphoma

Soham D. Puvvada, MD, Cassandra L Love, Vladimir Grubor, PhD, Jenny Zhang, Jason Smith, Sandeep S. Dave, MD
Journal: Blood
Blood (2011) 118 (21): 234.
https://doi.org/10.1182/blood.V118.21.234.234
Published: 2011
Journal Articles

SLCO1B1 Variation and Methotrexate Disposition in Children with Acute Lymphoblastic Leukemia: The Importance of Rare Variants in Pharmacogenetics

Laura B. Ramsey, PhD, Gitte H Bruun, Wenjian Yang, PhD, Lisa R Trevino, PhD, Selina Vattathil, Paul Scheet, PhD, Cheng Cheng, PhD, Gary Rosner, Kathleen Giacomini, PhD, Yiping Fan, PhD, Alex Sparreboom, PhD, Torben Mikkelsen, MD PhD, Thomas J Corydon, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2011) 118 (21): 571.
https://doi.org/10.1182/blood.V118.21.571.571
Published: 2011
Journal Articles

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Arrifin Hany, M.D., Ah Moy Tan, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.
Journal: Blood
Blood (2011) 118 (21): 567.
https://doi.org/10.1182/blood.V118.21.567.567
Published: 2011
Journal Articles

Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia

Clinical Trials & Observations
Russell E. Ware, Jenny M. Despotovic, Nicole A. Mortier, Jonathan M. Flanagan, Jin He, Matthew P. Smeltzer, Amy C. Kimble, Banu Aygun, Song Wu, Thad Howard, Alex Sparreboom
Journal: Blood
Blood (2011) 118 (18): 4985–4991.
https://doi.org/10.1182/blood-2011-07-364190
Published: 2011
Includes: Supplemental data
Journal Articles

Warfarin pharmacogenetics meets clinical use

Matthias Schwab, Elke Schaeffeler
Journal: Blood
Blood (2011) 118 (11): 2938–2939.
https://doi.org/10.1182/blood-2011-07-367763
Published: 2011
Journal Articles

Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy

Clinical Trials & Observations
Inna Y. Gong, Rommel G. Tirona, Ute I. Schwarz, Natalie Crown, George K. Dresser, Samantha LaRue, Nicole Langlois, Alejandro Lazo-Langner, Guangyong Zou, Dan M. Roden, C. Michael Stein, Marc Rodger, Marc Carrier, Melissa Forgie, Philip S. Wells, Richard B. Kim
Journal: Blood
Blood (2011) 118 (11): 3163–3171.
https://doi.org/10.1182/blood-2011-03-345173
Published: 2011
Includes: Supplemental data
Journal Articles

Pharmacogenetic Study of Deferasirox, An Iron Chelating Agent

Hyoung Jin Kang, Ji Won Lee, Ji-Yeob Choi, Nam Hee Kim, Mi Kyung Jang, Chang-Woo Yeo, Sang-Seop Lee, Eun Jong Han, Hyery Kim, Kyung Duk Park, Hee Young Shin, Jae-Gook Shin, Hyo Seop Ahn
Journal: Blood
Blood (2010) 116 (21): 2060.
https://doi.org/10.1182/blood.V116.21.2060.2060
Published: 2010