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Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2018) 132 (Supplement 1): 3216.

https://doi.org/10.1182/blood-2018-99-116500

Published: 2018

Journal Articles

The CDK4/6 Inhibitor Palbociclib Exerts Growth-Inhibitory Effects on Neoplastic Mast Cells and Synergizes with Midostaurin in Producing Growth Arrest

Mathias A. Schneeweiss, Gabriele Stefanzl, Daniela Berger, Gregor Eisenwort, Mohamad Jawhar, Greiner Georg, MD PhD, Gregor Hoermann, Wolfgang R. Sperr, Michel Arock, Andreas Reiter, MD, Peter Valent, Karoline V. Gleixner, MD

Blood (2018) 132 (Supplement 1): 1363.

https://doi.org/10.1182/blood-2018-99-116525

Published: 2018

Journal Articles

Reversible Macrocytosis with Cyclin Dependent Kinase Inhibitors

Jasmine Kamboj, MD, Elie Chalhoub, MD, Peter E. Friedell, MD MS

Blood (2018) 132 (Supplement 1): 4882.

https://doi.org/10.1182/blood-2018-99-113380

Published: 2018

Journal Articles

Hematopoietic, Immune Recovery and Outcomes after Autologous Stem Cell Transplantation Following Plerixafor Plus G-CSF Versus Chemotherapy and G-CSF Based Mobilization in Pediatric Patients

Jung Yoon Choi, MD, Hyoung Jin Kang, MD, Kyung Taek Hong, MD, Che Ry Hong, MD, Kyung Duk Park, MD, Hee Young Shin, MD

Blood (2017) 130 (Supplement 1): 2020.

https://doi.org/10.1182/blood.V130.Suppl_1.2020.2020

Published: 2017

Journal Articles

FVIII Proteins with a Modified Immunodominant T-Cell Epitope Exhibit Reduced Immunogenicity and Normal Procoagulant Activity

Ruth A. Ettinger, PhD, Joseph A. Liberman, PhD, Devi Gunasekera, BSSM, Eddie A. James, PhD, Arthur R. Thompson, MD PhD, Kathleen P. Pratt, PhD

Blood (2017) 130 (Supplement 1): 179.

https://doi.org/10.1182/blood.V130.Suppl_1.179.179

Published: 2017

Journal Articles

A Machine-Learning Analysis Suggests That FLX925, a FLT3/CDK4/6 Kinase Inhibitor, Is Potent Against FLT3-Wild Type Tumors Via Its CDK4/6 Activity

Gene Cutler, PhD, Jordan S Fridman, PhD

Blood (2016) 128 (22): 3520.

https://doi.org/10.1182/blood.V128.22.3520.3520

Published: 2016

Journal Articles

Rituximab-Induced CD20-Mediated Signals and Suppression of PI3K-AKT Pathway Cooperates to Inhibit B-Cell Lymphoma Growth By Down-Regulation of Myc.

Tsuyoshi Nakamaki, MD, Yuta Baba, MD, Maasa Abe, MD, Sou Murai, MD, Megumi Watanuki, MD, Nobuyuki Kabasawa, MD, Kouji Yanagisawa, MD, Norimichi Hattori, MD, Yukiko Kawaguchi, MD, Nana Arai, MD, Shun Fujiwara, MD, Bungo Saito, MD

Blood (2016) 128 (22): 5312.

https://doi.org/10.1182/blood.V128.22.5312.5312

Published: 2016

Journal Articles

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

João Agostinho Machado-Neto, PhD, Bruna Alves Fenerich, B.Sc., Renata Scopim-Ribeiro, M.Sc., Carlos Roberto Porto Dechandt, B.Sc., Ana Paula Nunes Rodrigues Alves, M.Sc., Jaqueline Cristina Fernandes, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Luciane Carla Alberici, PhD, Lorena Lôbo de Figueiredo Pontes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD

Blood (2016) 128 (22): 1960.

https://doi.org/10.1182/blood.V128.22.1960.1960

Published: 2016

Journal Articles

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Lynsey McKenzie, PhD, Natalia Martinez-Soria, PhD, Julia Draper, DPhil, Sirintra Nakjang, PhD, Helen J Blair, PhD, Christian Wichmann, MD, Josef Vormoor, MD FRCPCH, Constanze Bonifer, PhD, Georges Lacaud, PhD, Olaf Heidenreich, PhD

Blood (2016) 128 (22): 835.

https://doi.org/10.1182/blood.V128.22.835.835

Published: 2016

Journal Articles

Mir-10a Regulates Autophagy and Cell Cycle in Normal Karyotype Acute Myeloid Leukaemia

Timothy J Molloy, PhD, Thi T Vu, PhD, Friedrich Stölzel, MD, Gerhard Ehninger, MD, David Ma, MD

Blood (2016) 128 (22): 2862.

https://doi.org/10.1182/blood.V128.22.2862.2862

Published: 2016

Journal Articles

Clinical Activity of Abemaciclib (LY2835219), a Cell Cycle Inhibitor Selective for CDK4 and CDK6, in Patients with Relapsed or Refractory Mantle Cell Lymphoma

Blood (2014) 124 (21): 3067.

https://doi.org/10.1182/blood.V124.21.3067.3067

Published: 2014

Journal Articles

An Fc-Engineered CD133 Antibody for Induction of NK Cell Reactivity Against Cancer Cells

Kathrin Rothfelder, Julia Leibold, Ludger Grosse-Hovest, PhD, Hans-Joerg Buehring, PhD, Gundram Jung, MD, Lothar Kanz, MD, Helmut R Salih, MD

Blood (2014) 124 (21): 2739.

https://doi.org/10.1182/blood.V124.21.2739.2739

Published: 2014

Journal Articles

Proliferation-Independent Functions of the E2F-2 Transcription Factor during Terminal Erythroid Maturation

Kelsey Swartz, Gangjian Qin, MD, Alexander C Minella, MD

Blood (2014) 124 (21): 4356.

https://doi.org/10.1182/blood.V124.21.4356.4356

Published: 2014

Journal Articles

Targeting MYC Expression With CDK Inhibitors Shows Potency In Preclinical Models Of High-Risk Diffuse Large B-Cell Lymphom

Lingxiao Li, PhD, Praechompoo Pongtornpipat, Soham D. Puvvada, MD, Jonathan H. Schatz, MD

Blood (2013) 122 (21): 1831.

https://doi.org/10.1182/blood.V122.21.1831.1831

Published: 2013

Journal Articles

Impaired Erythropoiesis Of Gfi-1 Null Hematopoietic Progenitor Cells Is Rescued By Reducing Id2 Levels

Wonil Kim, Ph.D., Kimberly D Klarmann, Ph.D., Jonathan R Keller, Ph.D.

Blood (2013) 122 (21): 737.

https://doi.org/10.1182/blood.V122.21.737.737

Published: 2013

Journal Articles

BCOR Mutations Represent an Independent Factor of Poor Prognosis in Myelodysplastic Syndromes

Blood (2012) 120 (21): 1697.

https://doi.org/10.1182/blood.V120.21.1697.1697

Published: 2012

Journal Articles

BCOR Is Involved in Myeloid Cell Growth Control by Regulating Hox Genes

Qi Cao, Sigal Gery, PhD, Seyedmehdi Shojaee, Micah Gearhart, Vivian Bardwell, PhD, Markus Muschen, MD, H. Phillip Koeffler

Blood (2012) 120 (21): 3445.

https://doi.org/10.1182/blood.V120.21.3445.3445

Published: 2012

Journal Articles

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

Phillip M. Garfin, MD, PhD, Patrick Viatour, PharmD, PhD, Dullei Min, PhD, Jerrod Bryson, PhD, Kenneth I. Weinberg, MD, Nancy R. Manley, PhD, Julien Sage, PhD

Blood (2012) 120 (21): 835.

https://doi.org/10.1182/blood.V120.21.835.835

Published: 2012

Journal Articles

Preliminary Results of a Phase 2 Study of PD 0332991 in Combination with Bortezomib and Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma

Ruben Niesvizky, MD, Luciano J Costa, MD, PhD, Nisreen A. Haideri, MD, Georg Hess, Seema Singhal, MD, Ivan Spicka, MD, PhD, Edward A. Stadtmauer, MD, Ashraf Z. Badros, MD, Marc S Raab, John L Jakubczak, PhD, Sindy T. Kim, BS, Sophia Randolph, MD, PhD, Scott A Ely, M.D., Selina Chen-Kiang, PhD

Blood (2011) 118 (21): 2940.

https://doi.org/10.1182/blood.V118.21.2940.2940

Published: 2011

Journal Articles

Fluorescence In Situ Hybridization (FISH) Analysis In 160 Patients with IgM Monoclonal Gammopathies

Norma C. Gutierrez, Roberto JP Magalhaes, Ramón García-Sanz, María-Belén Vidriales, Enrique M. Ocio, Bruno Paiva, Daniel del Carpio, Alvaro Caballero, Jennifer Alonso, Lucia Lopez-Anglada, Teresa Villaescusa, Jesus M. Hernandez Rivas, A. Aguilar, Alejandro Martín, R. Lopez, Alberto Orfao, Jesus F San Miguel

Blood (2010) 116 (21): 1916.

https://doi.org/10.1182/blood.V116.21.1916.1916

Published: 2010

NARROW

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

The CDK4/6 Inhibitor Palbociclib Exerts Growth-Inhibitory Effects on Neoplastic Mast Cells and Synergizes with Midostaurin in Producing Growth Arrest

Reversible Macrocytosis with Cyclin Dependent Kinase Inhibitors

Hematopoietic, Immune Recovery and Outcomes after Autologous Stem Cell Transplantation Following Plerixafor Plus G-CSF Versus Chemotherapy and G-CSF Based Mobilization in Pediatric Patients

FVIII Proteins with a Modified Immunodominant T-Cell Epitope Exhibit Reduced Immunogenicity and Normal Procoagulant Activity

A Machine-Learning Analysis Suggests That FLX925, a FLT3/CDK4/6 Kinase Inhibitor, Is Potent Against FLT3-Wild Type Tumors Via Its CDK4/6 Activity

Rituximab-Induced CD20-Mediated Signals and Suppression of PI3K-AKT Pathway Cooperates to Inhibit B-Cell Lymphoma Growth By Down-Regulation of Myc.

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

Identification of CCND2 As a RUNX1/ETO Target Required for Leukaemic Propagation

Mir-10a Regulates Autophagy and Cell Cycle in Normal Karyotype Acute Myeloid Leukaemia

Clinical Activity of Abemaciclib (LY2835219), a Cell Cycle Inhibitor Selective for CDK4 and CDK6, in Patients with Relapsed or Refractory Mantle Cell Lymphoma

An Fc-Engineered CD133 Antibody for Induction of NK Cell Reactivity Against Cancer Cells

Proliferation-Independent Functions of the E2F-2 Transcription Factor during Terminal Erythroid Maturation

Targeting MYC Expression With CDK Inhibitors Shows Potency In Preclinical Models Of High-Risk Diffuse Large B-Cell Lymphom

Impaired Erythropoiesis Of Gfi-1 Null Hematopoietic Progenitor Cells Is Rescued By Reducing Id2 Levels

BCOR Mutations Represent an Independent Factor of Poor Prognosis in Myelodysplastic Syndromes

BCOR Is Involved in Myeloid Cell Growth Control by Regulating Hox Genes

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

Preliminary Results of a Phase 2 Study of PD 0332991 in Combination with Bortezomib and Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma

Fluorescence In Situ Hybridization (FISH) Analysis In 160 Patients with IgM Monoclonal Gammopathies

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American Society of Hematology

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ASH Publications

American Society of Hematology

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