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Journal Articles

Senicapoc, a Gardos Channel Inhibitor Developed to Treat Sickle Cell Disease, Exhibits Antimalarial Activity

Venee N. Tubman, MD MMSc, Pedro Mejia, PhD, Boris E. Shmukler, PhD, Seth L. Alper, MD PhD, James R. Mitchell, PhD, Carlo Brugnara, MD, Manoj T. Duraisingh, PhD
Journal: Blood
Blood (2014) 124 (21): 743.
https://doi.org/10.1182/blood.V124.21.743.743
Published: 2014
Journal Articles

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

Clinical Trials & Observations
Kenneth I. Ataga, Wally R. Smith, Laura M. De Castro, Paul Swerdlow, Yogen Saunthararajah, Oswaldo Castro, Elliot Vichinsky, Abdullah Kutlar, Eugene P. Orringer, Greg C. Rigdon, Jonathan W. Stocker
Journal: Blood
Blood (2008) 111 (8): 3991–3997.
https://doi.org/10.1182/blood-2007-08-110098
Published: 2008
Includes: Supplemental data
Journal Articles

A 48-Week Open-Label Study of Senicapoc (ICA-17043), a Gardos Channel Blocker, in Patients with Sickle Cell Disease.

Paul Swerdlow, MD, Kenneth Ataga, MD, Wally Smith, MD, Yogen Saunthararajah, MD, Jonathan W. Stocker, PhD
Journal: Blood
Blood (2006) 108 (11): 685.
https://doi.org/10.1182/blood.V108.11.685.685
Published: 2006
Journal Articles

Efficacy and Safety of the Gardos Channel Inhibitor, ICA-17043, in Patients with Sickle Cell Anemia.

Kenneth I. Ataga, MBBS, Laura M. DeCastro, MD, Paul Swerdlow, MD, Yogen Saunthararajah, MD, Wally Smith, MD, The ICA-17043 Study Investigators6
Journal: Blood
Blood (2004) 104 (11): 103.
https://doi.org/10.1182/blood.V104.11.103.103
Published: 2004
Journal Articles

ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice

Jonathan W. Stocker, Lucia De Franceschi, Grant A. McNaughton-Smith, Roberto Corrocher, Yves Beuzard, Carlo Brugnara
Journal: Blood
Blood (2003) 101 (6): 2412–2418.
https://doi.org/10.1182/blood-2002-05-1433
Published: 2003