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Journal Articles

New developments in diagnosis, prognostication, and treatment of advanced systemic mastocytosis

Andreas Reiter, Tracy I. George, Jason Gotlib

Blood (2020) 135 (16): 1365–1376.

https://doi.org/10.1182/blood.2019000932

Published: 2020

Journal Articles

UK Single Institution Experience of Mastocytosis: Guy's and St Thomas' NHS Foundation Trust

Clare Oni, MD, Mufaddal Moonim, MD, Joana Desterro, MD, Clive Grattan, MD, Natalia Curto-Garcia, MD, Claire Woodley, Monika Ciesielska, Deimante Drasutyte, Yvonne Francis, Jennifer O'Sullivan, MD, Thompson Olaoni, Anna Green, MD, Miki Yurina, MD, Mark Ong, MD, Nick C.P. Cross, Professor, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath, Deepti Radia

Blood (2019) 134 (Supplement_1): 2960.

https://doi.org/10.1182/blood-2019-130477

Published: 2019

Journal Articles

Pioneer: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis with Symptoms Inadequately Controlled with Standard Therapy

Blood (2019) 134 (Supplement_1): 2950.

https://doi.org/10.1182/blood-2019-126035

Published: 2019

Journal Articles

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

Myriam Salazar-Terreros, PhDMSc, Kleber Yotsumoto Fertrin, MD PhD, Nicolas Moreno Reyes, PhD, Fernando Ferreira Costa, MD PhD, Carla F. Franco-Penteado, BSc, PhD

Blood (2019) 134 (Supplement_1): 3566.

https://doi.org/10.1182/blood-2019-129509

Published: 2019

Journal Articles

Clinical Utility of a Multi-Gene Next-Generation Sequencing Myeloid Panel in an Academic Hematology Practice

Pedro G Vianna, BSc,MD, Richard D. Press, MD PhD, Henning Stehr, PhD, Fei Yang, MD, Linda Gojenola, James L Zehnder, Jason Gotlib, MD MS

Blood (2019) 134 (Supplement_1): 1408.

https://doi.org/10.1182/blood-2019-124445

Published: 2019

Journal Articles

An Increased Bone Mineral Density As an Adverse Prognostic Factor in Patients with Systemic Mastocytosis

Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, PhD, Stefan O Schoenberg, Wolf-Karsten Hofmann, MD PhD, Philipp Riffel, Andreas Reiter

Blood (2019) 134 (Supplement_1): 4185.

https://doi.org/10.1182/blood-2019-129798

Published: 2019

Journal Articles

A New Prognostic Score for Advanced Systemic Mastocytosis Based on Clinical and Genetic Characteristics of 210 Consecutive Patients

Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Georgia Metzgeroth, MD, Hans-Peter Horny, Karl Sotlar, Manja Meggendorfer, PhD, Torsten Haferlach, MD, Nicholas C.P. Cross, Alice Fabarius, Wolf-Karsten Hofmann, Peter Valent, Andreas Reiter, MD

Blood (2018) 132 (Supplement 1): 349.

https://doi.org/10.1182/blood-2018-99-115804

Published: 2018

Journal Articles

Molecular Quantification of Tissue Mast Cell Burden in Systemic Mastocytosis: A New Approach for Diagnostics and Prognostication

Greiner Georg, MD PhD, Michael Gurbisz, MSc, Franz Ratzinger, MD, Nadine Witzeneder, MSc, Svenja-Verena Class, Ingrid Simonitsch-Klupp, MD, Harald Esterbauer, MD PhD, Matthias Mayerhofer, MD, Wolfgang R. Sperr, Leonhard Muellauer, MD PhD, Peter Valent, Gregor Hoermann

Blood (2018) 132 (Supplement 1): 3043.

https://doi.org/10.1182/blood-2018-99-116492

Published: 2018

Journal Articles

Distinct Diagnostic and Clinical Features of Bone Marrow Mastocytosis: A Study of the Registry of the European Competence Network on Mastocytosis (ECNM)

Massimiliano Bonifacio, MD, Patrizia Bonadonna, MD, Hanneke Oude Elberink, MD, Björn van Anrooij, MD, Aleksandra Górska, MD, Magdalena Lange, MD, Emir Hadzijusufovic, DVM, Luigi Scaffidi, Ilaria Tanasi, MD, Cecelia Perkins, Virginia Valeria Ferretti, Anja Illerhaus, PhD, Thilo Jakob, MD, Roberta Parente, MD, Mohamad Jawhar, MD, Francesca Caroppo, MD, Alexander Zink, MD, Alex Kilbertus, MD, Akif Selim Yavuz, MD, Michael Doubek, MD PhD, Hans Hagglund, MD PhD, Jens P. Panse, MD, Vito Sabato, MD PhD, Elisabeth Aberer, MD, Nadja Jaekel, MD, Peter Vandenberghe, MD PhD, David Fuchs, MD, Knut Brockow, MD, Anna Belloni Fortina, MD, Andreas Reiter, MD, Massimo Triggiani, MD, Khalid Shoumariyeh, MD, Karin Hartmann, MD, Chiara Elena, Olivier Hermine, MD PhD, Jason Gotlib, MD, Marek Niedoszytko, MD, Hanneke Kluin-Nelemans, MD PhD, Wolfgang R. Sperr, MD, Peter Valent, MD, Roberta Zanotti, MD

Blood (2017) 130 (Supplement 1): 4200.

https://doi.org/10.1182/blood.V130.Suppl_1.4200.4200

Published: 2017

Journal Articles

Phase 2 Study of Brentuximab Vedotin in Patients with Advanced Systemic Mastocytosis

John H. Baird, Srdan Verstovsek, MD PhD, Tracy I. George, Isabel Reyes, Justin Abuel, Cecelia Perkins, Cheryl Langford, Kurt Schroeder, Jason Gotlib, MD

Blood (2017) 130 (Supplement 1): 2909.

https://doi.org/10.1182/blood.V130.Suppl_1.2909.2909

Published: 2017

Journal Articles

Clinical Activity in a Phase 1 Study of Blu-285, a Potent, Highly-Selective Inhibitor of KIT D816V in Advanced Systemic Mastocytosis (AdvSM)

Daniel J. DeAngelo, MD, Albert Thomas Quiery, MD, Deepti Radia, MD, Mark W Drummond, MB ChB, PhD FRCPath, Jason Gotlib, MD, William A Robinson, MD PhD, Elizabeth Hexner, MDMS, Srdan Verstovsek, MD PhD, Hongliang Shi, Terri Alvarez-Diez, Oleg Schmidt-Kittler, Erica Evans, PhD, Mary Ellen Healy, Beni B. Wolf, MD PhD, Michael W. Deininger, MD PhD

Blood (2017) 130 (Supplement 1): 2.

https://doi.org/10.1182/blood.V130.Suppl_1.2.2

Published: 2017

Journal Articles

Systemic Mastocytosis with Associated Acute Myeloid Leukemia (SM-AML): a Poor-Risk Multi-Mutated Disease That Follows a Distinct Diagnostic Algorithm and Requires High-Dose Stem Cell-Targeting Therapy

Blood (2017) 130 (Supplement 1): 2916.

https://doi.org/10.1182/blood.V130.Suppl_1.2916.2916

Published: 2017

Journal Articles

Systematic KIT Sequencing Identifies Unsuspected Systemic Mastocytosis with Associated Hematological Neoplasm

Elizabeth A Morgan, MD, Jeffrey W. Craig, MD PhD, Annette S. Kim, MDPhD, Geraldine S. Pinkus, Jon C. Aster, MD PhD, Frank C Kuo, MBBS, PhD, David P. Steensma, MD, R. Coleman Lindsley, MD PhD, Daniel J. DeAngelo, MD

Blood (2017) 130 (Supplement 1): 2923.

https://doi.org/10.1182/blood.V130.Suppl_1.2923.2923

Published: 2017

Journal Articles

Evolution of Chronic Pain in Sickle Cell Disease

Michael Pope, BA, Camila Albo, Kyle Michael Kidwell, BS, Hongyan Xu, PhD, Latanya Bowman, BSN, Leigh Wells, MSN, Nadine Barrett, MSN, Sabine Fields, BSN, Pritam Bora, BA, E. Leila Jerome Clay, MD, Niren Patel, MBBS, Abdullah Kutlar, MD

Blood (2016) 128 (22): 1297.

https://doi.org/10.1182/blood.V128.22.1297.1297

Published: 2016

Journal Articles

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

Mohamad Jawhar, MD, Juliana Schwaab, MD, Manja Meggendorfer, PhD, Nicole Naumann, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Karla Schmitt, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD, Andreas Reiter, MD

Blood (2016) 128 (22): 3109.

https://doi.org/10.1182/blood.V128.22.3109.3109

Published: 2016

Journal Articles

Characterization of Mast Cell Activation Syndrome

Lawrence B Afrin, MD, Sally Self, MD, Jeremiah Menk, M.S., John Lazarchick, MD

Blood (2016) 128 (22): 3683.

https://doi.org/10.1182/blood.V128.22.3683.3683

Published: 2016

Journal Articles

Aleukemic Mast Cell Leukemia (aMCL) - Clinical Characteristics and Outcomes

Preetesh Jain, MBBS, MDDM, PhD, Sa Wang, MD, Hagop M. Kantarjian, MD, Nawid Sarwari, Keyur P. Patel, MD PhD, Prithviraj Bose, MD, Sherry Pierce, BSN, BA, Tapan M. Kadia, MD, Naval Daver, MD, Naveen Pemmaraju, MD, Jorge E. Cortes, MD, Srdan Verstovsek, MD PhD

Blood (2016) 128 (22): 4255.

https://doi.org/10.1182/blood.V128.22.4255.4255

Published: 2016

Journal Articles

Inhibitory Effects of Midostaurin and Blu-285 on Myeloid Progenitor Cells Derived from Patients with Multi-Mutated KIT D816V+ Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Nicole Naumann, Sebastian Kluger, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Erica K. Evans, PhD, Alexandra Gardino, PhD, Christoph Lengauer, PhD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD

Blood (2016) 128 (22): 1964.

https://doi.org/10.1182/blood.V128.22.1964.1964

Published: 2016

Journal Articles

Prognotic Impact of Mutations in Systemic Mastocytosis

Lisa Pieri, MD PhD, Giada Rotunno, MSc, PhD, Francesca Gesullo, MSc, Tiziana Fanelli, MSc, Giuditta Corbizi Fattori, MSc, Annalisa Pacilli, PhD, Federica Scarfì, MD, Maria Loredana Iorno, MD, Fabio Almerigogna, MD, Roberto Salerno, MD, Paola Guglielmelli, MD PhD, Roberta Zanotti, MD, Alessandro M. Vannucchi, MD

Blood (2016) 128 (22): 1953.

https://doi.org/10.1182/blood.V128.22.1953.1953

Published: 2016

Journal Articles

Ruxolitinib Used to Treat Hypereosinophilic Syndrome

Seung Lee, bs, Coby Palmares, Niko Koutsoukos, J. Brice Weinberg, MD, Trisa Palmares, MD, Alice Song, MD, Harold Song, MD, Sheila Benedicto, bs, Michael Song, bs, Vu Phan, MD, Julia Song, MD

Blood (2016) 128 (22): 5500.

https://doi.org/10.1182/blood.V128.22.5500.5500

Published: 2016

NARROW

New developments in diagnosis, prognostication, and treatment of advanced systemic mastocytosis

UK Single Institution Experience of Mastocytosis: Guy's and St Thomas' NHS Foundation Trust

Pioneer: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis with Symptoms Inadequately Controlled with Standard Therapy

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

Clinical Utility of a Multi-Gene Next-Generation Sequencing Myeloid Panel in an Academic Hematology Practice

An Increased Bone Mineral Density As an Adverse Prognostic Factor in Patients with Systemic Mastocytosis

A New Prognostic Score for Advanced Systemic Mastocytosis Based on Clinical and Genetic Characteristics of 210 Consecutive Patients

Molecular Quantification of Tissue Mast Cell Burden in Systemic Mastocytosis: A New Approach for Diagnostics and Prognostication

Distinct Diagnostic and Clinical Features of Bone Marrow Mastocytosis: A Study of the Registry of the European Competence Network on Mastocytosis (ECNM)

Phase 2 Study of Brentuximab Vedotin in Patients with Advanced Systemic Mastocytosis

Clinical Activity in a Phase 1 Study of Blu-285, a Potent, Highly-Selective Inhibitor of KIT D816V in Advanced Systemic Mastocytosis (AdvSM)

Systemic Mastocytosis with Associated Acute Myeloid Leukemia (SM-AML): a Poor-Risk Multi-Mutated Disease That Follows a Distinct Diagnostic Algorithm and Requires High-Dose Stem Cell-Targeting Therapy

Systematic KIT Sequencing Identifies Unsuspected Systemic Mastocytosis with Associated Hematological Neoplasm

Evolution of Chronic Pain in Sickle Cell Disease

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

Characterization of Mast Cell Activation Syndrome

Aleukemic Mast Cell Leukemia (aMCL) - Clinical Characteristics and Outcomes

Inhibitory Effects of Midostaurin and Blu-285 on Myeloid Progenitor Cells Derived from Patients with Multi-Mutated KIT D816V+ Advanced Systemic Mastocytosis

Prognotic Impact of Mutations in Systemic Mastocytosis

Ruxolitinib Used to Treat Hypereosinophilic Syndrome

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American Society of Hematology

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