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Journal Articles

Targeting Sirt6 with OSS_128167 Displays Anti-Tumor Activities in Diffuse Large B-Cell Lymphoma through Down-Regulation of PI3K Signaling

Juan Yang, MM, Xiangxiang Zhou, MD, Ying Li, MD, Ya Zhang, MD, Xiaosheng Fang, MD, Na Chen, MD, Xin Wang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5065.
https://doi.org/10.1182/blood-2019-127926
Published: 2019
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019
Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3718.
https://doi.org/10.1182/blood-2019-131124
Published: 2019
Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 879.
https://doi.org/10.1182/blood-2019-132139
Published: 2019
Journal Articles

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

Yihong Guan, Edward F Greenberg, MD, Metis Hasipek, PhD, Cassandra M. Hirsch, Amy C Graham, BS, MS, Tomas Radivoyevitch, PhD, Shi Chen, Xiaochen Liu, Valeria Visconte, PhD, Dewen You, PhD, Eiju Negoro, MD PhD, Bartlomiej P. Przychodzen, Hideki Makishima, MD PhD, Aziz Nazha, Daniel Gackowski, PhD, Ewelina Zarakowska, Mridul Mukherji, D.Phil., Mikkael A. Sekeres, MD MS, Mingjiang Xu, MD PhD, Ryszard Ólinski, Professor, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2018) 132 (Supplement 1): 4346.
https://doi.org/10.1182/blood-2018-99-119712
Published: 2018
Journal Articles

SIRT5 As a Therapeutic Target in Acute Myeloid Leukemia

Dongqing Yan, Anthony D. Pomicter, MS, William L. Heaton, MS, Clint C. Mason, PhD, Jonathan Ahmann, BS, Anna Senina, MS, Anca Franzini, PhD, Brayden Halverson, Hein Than, MD FRCPath, MRCP, Phillip M. Clair, MS, Jamshid S Khorashad, MD PhD, Thomas O'Hare, PhD, Michael W. Deininger, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 907.
https://doi.org/10.1182/blood-2018-99-115468
Published: 2018
Journal Articles

Targeting NAD + Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure

Phillip J Maciejewski, Yihong Guan, Metis Hasipek, PhD, Anand D. Tiwari, PhD, Dale Grabowski, BS, James G Phillips, PhD, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, Babal K. Jha
Journal: Blood
Blood (2018) 132 (Supplement 1): 3840.
https://doi.org/10.1182/blood-2018-99-119300
Published: 2018
Journal Articles

SIRT6 As a Potential Therapeutic Target in Diffuse Large B-Cell Lymphoma

Juan Yang, PhD, Ying Li, MD, Ya Zhang, MD, Xiangxiang Zhou, MD, Xin Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2862.
https://doi.org/10.1182/blood-2018-99-115823
Published: 2018
Journal Articles

Prostaglandin E2 Protects HSC from DNA Damage Induced By Ionizing Radiation By Preventing Generation of Reactive Oxygen Species and Histone Acetylation

Liqiong Liu, MD PhD, Andrea M Patterson, PhD, Hui Lin Chua, PhD, Carol Sampson, MS, Artur Plett, PhD, Hongge Li, PhD, Pratibha Singh, PhD, Christie M. Orschell, PhD, Louis M. Pelus, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1151.
https://doi.org/10.1182/blood.V130.Suppl_1.1151.1151
Published: 2017
Journal Articles

Cell-Stage Dependent Outcomes of the NAMPT/SIRT2-Mediated Activation of LMO2 By Deacetylation in Normal Hematopoiesis and in T-ALL

Tatsuya Morishima, MD PhD, Christian Lindner, Benedikt Oswald, Marcus Hartmann, Masoud Nasri, MSc, Lothar Kanz, Patrick Müller, Karl Welte, Julia Skokowa
Journal: Blood
Blood (2017) 130 (Supplement 1): 1154.
https://doi.org/10.1182/blood.V130.Suppl_1.1154.1154
Published: 2017
Journal Articles

SIRT3 Is a Novel Metabolic Driver of and Therapeutic Target for Chemotherapy Resistant Dlbcls

Meng Li, PhD, Ying-Ling Chiang, PhD, Costas Lyssiotis, PhD, Matthew Teater, PhD, Hao Shen, MD, Ling Wang, MS, Jun Young Hong, BS, Hui Jin, PhD, Cihangir Duy, PhD, Sucharita Mistry, PhD, Leandro Cerchietti, MD, Justin Cross, PhD, Lewis Cantley, MD, Hening Lin, PhD, Ari Melnick, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 643.
https://doi.org/10.1182/blood.V130.Suppl_1.643.643
Published: 2017
Journal Articles

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Kristy Stengel, PhD, Srividya Bhaskara, PhD, Jing Wang, PhD, Qi Liu, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 311.
https://doi.org/10.1182/blood.V130.Suppl_1.311.311
Published: 2017
Journal Articles

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

Emilia Bialopiotrowicz, PhD, Tomasz Sewastianik, PhD, Monika Noyszewska-Kania, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Patryk Gorniak, PhD, Anna Polak, PhD, Przemyslaw Kiliszek, PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4120.
https://doi.org/10.1182/blood.V128.22.4120.4120
Published: 2016
Journal Articles

SIRT2 Plays Essential Role in Early Hematopoiesis through Deacetylation of LMO2 Protein

Tatsuya Morishima, MD PhD, Regine Bernhard, Azadeh Zahabi, Benjamin Dannenmann, Masoud Nasri, M.Sc, Bardia Samareh, PhD, Lothar Kanz, Prof. Dr. MD, Karl Welte, MD, Julia Skokowa, Prof. Dr.
Journal: Blood
Blood (2015) 126 (23): 3574.
https://doi.org/10.1182/blood.V126.23.3574.3574
Published: 2015
Journal Articles

Functional Characterization of NAD Dependent De-Acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL)

Savita Bhalla, PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2015) 126 (23): 4141.
https://doi.org/10.1182/blood.V126.23.4141.4141
Published: 2015
Journal Articles

The Mechanism of Type I Interferon-Mediated Polarization of Tumor-Associated Neutrophils in Mice and Human

Lisa Andzinski, PhD, Mozhgan Dehghan Harati, Edyta Zyla, Nadine Kasnitz, Stephanie Stahnke, Ching-Fang Wu, MD PhD, Marcus Gereke, PhD, Maren von Köckritz-Blickwede, PhD, Bastian Schilling, MD, Sven Brandau, PhD, Lothar Kanz, MD, Karl Welte, MD, Siegfried Weiss, PhD, Julia Skokowa, Prof. Dr., Jadwiga Jablonska, PhD
Journal: Blood
Blood (2015) 126 (23): 644.
https://doi.org/10.1182/blood.V126.23.644.644
Published: 2015
Journal Articles

Small Molecule Inhibition of SIRT Activity: A Novel Therapeutic Approach for Refractory Multiple Myeloma

Steffan T. Nawrocki, PhD, Claudia M. Espitia, Valeria Visconte, PhD, Yingchun Han, MD, Kevin R. Kelly, MD PhD, Jennifer S. Carew, PhD
Journal: Blood
Blood (2015) 126 (23): 1807.
https://doi.org/10.1182/blood.V126.23.1807.1807
Published: 2015
Journal Articles

SIRT3 Modulates Mitochondrial Stress Response in Bone Marrow Mesenchymal Stromal Cells of Multiple Myeloma Patients

Rimma Berenstein, Igor Wolfgang Blau, MD PhD, Axel Nogai, MD, Marlies Waechter, Martin Schmidt-Hieber, MD PhD, Antonio Pezzutto, MD PhD, Bernd Doerken, MD PhD, Olga Blau, MD PhD
Journal: Blood
Blood (2015) 126 (23): 5325.
https://doi.org/10.1182/blood.V126.23.5325.5325
Published: 2015
Journal Articles

Multiple Myeloma Cells Induce Mitochondrial Stress Response in Bone Marrow Mesenchymal Stromal Cells

Rimma Berenstein, Olga Blau, MD PhD, Axel Nogai, MD, Marlies Wächter, Martin Schmidt-Hieber, MD, Antonio Pezzutto, MD PhD, Bernd Dörken, MD PhD, Igor Wolfgang Blau, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3357.
https://doi.org/10.1182/blood.V124.21.3357.3357
Published: 2014
Journal Articles

Sirt1 Expression Related with Sarcoma Growth after Stem Cell Transplantation Combined with Depletion of Myeloid-Derived Suppressor Cells

Ming Li, MD, PhD/ Associate Professor, Ming Shi, MD, PhD, Yunze Cui, MD, PhD, Yasushi Adachi, MD, PhD, Susumu Ikehara, MD, PhD/Professor
Journal: Blood
Blood (2014) 124 (21): 5796.
https://doi.org/10.1182/blood.V124.21.5796.5796
Published: 2014