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Journal Articles

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Nick R Anderson, BS, Hui Li, BS, Mason W Harris, Shaowei Qiu, MD, Andrew J Paterson, PhD, Ravi Bhatia, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 909.
https://doi.org/10.1182/blood-2019-124379
Published: 2019
Journal Articles

Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo

Elliott J. Hagedorn, PhD, Julie R. Perlin, PhD, Rebecca J. Freeman, BS, Clara Mao, BS, Inés Fernández-Maestre, BS, Madeleine L. Daily, B.S., Christopher R. D'Amato, B.S., Samuel J. Wattrus, B.S., Tianxiao Han, BS, Michael J. Fairchild, PhD, Raquel Riquelme, Brian Li, B.S., Shelby E. Redfield, B.S., Samantha H. Collins, B.S., Asher Lichtig, BS, Song Yang, PhD, Yi Zhou, Balvir Kunar, Jesus M Gomez-Salinero, PhD, Theresa T. Dinh, PhD, Junliang Pan, MD PhD, Karoline Holler, B.S., Eugene Butcher, Alexander Van Oudenaarden, Shahin Rafii, MD, Jan Philipp Junker, PhD, Leonard I Zon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 525.
https://doi.org/10.1182/blood-2019-127219
Published: 2019
Journal Articles

Molecular Insights at the Single Cell Level into the Reprogramming of Human Hematopoietic Stem Cells during Epigenetically Modified Ex Vivo Expansion

Peng Hua, PhD, Barbara Kronsteiner, PhD, Neil Ashley, PhD, Mark van der Garde, PhD, Diana Hernandez, PhD, Marina Tarunina, PhD, Lilian Hook, PhD, Yen Choo, PhD, Irene Roberts, MD, Adam J Mead, MD PhD, Suzanne M Watt, PhDFRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 2425.
https://doi.org/10.1182/blood.V130.Suppl_1.2425.2425
Published: 2017
Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3781.
https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781
Published: 2017
Journal Articles

Splenic Red Pulp Macrophages Provide a Secondary Stem Cell Niche for Chronic Myeloid Leukemia Stem Cells

Elias D Bührer, MD, Michael A Amrein, MD, Stephan Isringhausen, Cesar Nombela-Arrieta, Carsten Riether, PhD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2861.
https://doi.org/10.1182/blood.V130.Suppl_1.2861.2861
Published: 2017
Journal Articles

CCL3 is a key mediator for the leukemogenic effect of Ptpn11 -activating mutations in the stem-cell microenvironment

Lei Dong, Hong Zheng, Cheng-Kui Qu
Journal: Blood
Blood (2017) 130 (12): 1471–1474.
https://doi.org/10.1182/blood-2017-06-791103
Published: 2017
Includes: Supplemental data
Journal Articles

Hacking the stem cell niche

Steven W. Lane, Florian H. Heidel
Journal: Blood
Blood (2017) 129 (22): 2951–2952.
https://doi.org/10.1182/blood-2017-04-777789
Published: 2017
Journal Articles

Effects of the Sympathicomimetic Agonist Mirabegron on Disease Course, Mutant Allele Burden, Marrow Fibrosis, and Nestin Positive Stem Cell Niche in Patients with JAK2 -Mutated Myeloproliferative Neoplasms. a Prospective Multicenter Phase II Trial SAKK 33/14

Beatrice Drexler, MD, Jakob Passweg, MD, Martin Bigler, Alexandre PA Theocharides, MD, Nathan Cantoni, MD, Peter Keller, MD, Georg Stuessi, MD, Axel Rüfer, MD, Rudolf A. Benz, MD, Geneviève Favre, MD, Alexandar Tzankov, MD, Pontus Lundberg, PhD, Andrea Fuhrer, PhD, Christine Biaggi, Markus G Manz, MD, Mario Bargetzi, MD, Simon Mendez-Ferrer, PhD, Radek C. Skoda, MD
Journal: Blood
Blood (2016) 128 (22): 3108.
https://doi.org/10.1182/blood.V128.22.3108.3108
Published: 2016
Journal Articles

Hemostasis keeps the stem cell niche in order

Wolfram Ruf
Journal: Blood
Blood (2016) 128 (8): 1027–1029.
https://doi.org/10.1182/blood-2016-07-722421
Published: 2016
Journal Articles

5-Fluorouracil Treatment Leads to Activation of Stem Cell Niche By Reconstructing Mesenchymal Stromal Cells and Exert a Distinct Microenvironmental Impact on Normal and Leukemic Cells

Seon-Yeong Jeong, Jin-A Kim, Il-Hoan Oh, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1197.
https://doi.org/10.1182/blood.V126.23.1197.1197
Published: 2015
Journal Articles

Oncostatin M Enhances Hematopoietic Stem Cell Homing and Engraftment

Hannah K Rasmussen, Frankie Wong, BA, Tiffany Tate, BS, David T. Scadden, MD, Jonathan Hoggatt, PhD
Journal: Blood
Blood (2015) 126 (23): 31.
https://doi.org/10.1182/blood.V126.23.31.31
Published: 2015
Journal Articles

Adaptation of Marrow Osteoblast Morphology Mediated By a Hematopoietic-Derived Endosteal Cell Is Critical for Donor HSC Engraftment after BMT

Kathleen Overholt, MD, Satoru Otsuru, Victoria Best, Adam Guess, Timothy S. Olson, MD PhD, Massimo Dominici, MD, Edwin M. Horwitz, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3603.
https://doi.org/10.1182/blood.V126.23.3603.3603
Published: 2015
Journal Articles

Noncellular Niche Influences: Nervous System Mediators, Metabolic Mediators, and Hypoxia/Oxidative Stress

Simón Méndez-Ferrer, PhD
Journal: Blood
Blood (2015) 126 (23): SCI-26.
https://doi.org/10.1182/blood.V126.23.SCI-26.SCI-26
Published: 2015
Journal Articles

The hematopoietic stem cell niche in homeostasis and disease

Laura M. Calvi, Daniel C. Link
Journal: Blood
Blood (2015) 126 (22): 2443–2451.
https://doi.org/10.1182/blood-2015-07-533588
Published: 2015
Journal Articles

Macrophages and Bone Marrow Stem Cell Niches: The Roles of PGE2 and Coagulation

Tsvee Lapidot, PhD
Journal: Blood
Blood (2014) 124 (21): SCI-8.
https://doi.org/10.1182/blood.V124.21.SCI-8.SCI-8
Published: 2014
Journal Articles

Kit Deficiency Regulates Stable Human Hematopoietic Stem Cell Engraftment in Mice

Claudia Waskow, PhD, Susann Rahmig, Nehir Cosgun
Journal: Blood
Blood (2014) 124 (21): 653.
https://doi.org/10.1182/blood.V124.21.653.653
Published: 2014
Journal Articles

EphA3 Is Expressed on Leukemia Stem Cells, and Eph/Ephrin Signalling Features in the Remodelling of the Leukemia Stem Cell Niche

Christopher I Slape, PhD
Journal: Blood
Blood (2014) 124 (21): 4783.
https://doi.org/10.1182/blood.V124.21.4783.4783
Published: 2014
Journal Articles

Exosomes Derived from AML/MDS Cells Is Involved in Stromal Dysfunction and Bone Marrow Failure

Hiroto Horiguchi, MD, Masayoshi Kobune, MD PhD, Shohei Kikuchi, MD PhD, Wataru Jomen, MD, Kazuyuki Murase, MD PhD, Soushi Ibata, MD, Satoshi Iyama, MD PhD, Tsutomu Sato, MD PhD, Yusuke Kamihara, MD, Koji Miyanishi, MD PhD, Yasushi Sato, MD PhD, Tsuyoshi Hayashi, MD PhD, Rishu Takimoto, MD PhD, Junji Kato, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4627.
https://doi.org/10.1182/blood.V124.21.4627.4627
Published: 2014
Journal Articles

Runx1 Maintains Granulocytic-Monocytic Progenitor Numbers By Negatively Regulating Interactions with the Stem Cell Niche

Carol Stocking, Kira Behrens, Birte Niebuhr, Ursula Mueller
Journal: Blood
Blood (2014) 124 (21): 2913.
https://doi.org/10.1182/blood.V124.21.2913.2913
Published: 2014
Journal Articles

Targeting on the Stem Cell Niche Can Protect Hematopoietic Stem Cell from Chemotherapy and G-CSF

Sidan Li, MD, Qiongli Zhai, PhD, Dehui Zou, MD, Changhong Li, Lugui Qiu, MD
Journal: Blood
Blood (2014) 124 (21): 5790.
https://doi.org/10.1182/blood.V124.21.5790.5790
Published: 2014