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Journal Articles

Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis

Blood (2021) 137 (15): 2070–2084.

https://doi.org/10.1182/blood.2019004509

Published: 2021

Includes: Supplemental data

Journal Articles

Role of Thrombopoietin in Stimulating Megakaryopoiesis of ITP Patients Via Rescuing Vascular Niche

Yingying Jiao, Graduate Student, Xiaoyuan Zeng, Graduate Student, Zongpeng Li, Graduate Student, Beng H Chong, MBBS, PhD, Yujiao Zhang, Graduate Student, Jieyu Ye

Blood (2019) 134 (Supplement_1): 1063.

https://doi.org/10.1182/blood-2019-125679

Published: 2019

Journal Articles

Concurrent Treatment of VEGFR Tyrosine Kinase Inhibitors (TKIs) and Factor Xa Inhibitors Is Associated with Increased Bleeding Risks

Sandip Patel, MBBS, Tiffany George, MD, Tzu-Fei Wang, MD MPH, Sherry Mori Vogt, Pharm D, Edmund Folefac, MD, Ming Yin, MD

Blood (2019) 134 (Supplement_1): 3681.

https://doi.org/10.1182/blood-2019-130465

Published: 2019

Journal Articles

High Serum VEGF Level in Erdheim-Chester Disease: Correlation with Cardiovascular Involvement and Response to Treatment

Anaïs Roeser, MD, Marine Bravetti, MD, Levi-Dan Azoulay, MD, Makoto Miyara, MD, Jean-François Emile, MD, Jean Donadieu, MD PhD, Zahir Amoura, MD MSc, Fleur Cohen-Aubart, MD PhD, Julien Haroche

Blood (2019) 134 (Supplement_1): 2324.

https://doi.org/10.1182/blood-2019-129984

Published: 2019

Journal Articles

Genome-Wide CRISPR Screening Identifies MAPK and Mtorc Pathways As Regulators of Sorafenib Resistance in Acute Myeloid Leukemia

Alisa Damnernsawad, PhD, Tamilla Nechiporuk, PhD, Daniel Bottomly, MS, Stephen E Kurtz, PhD, Christopher A. Eide, Shannon K. McWeeney, PhD, Jeffrey W. Tyner

Blood (2019) 134 (Supplement_1): 2557.

https://doi.org/10.1182/blood-2019-128877

Published: 2019

Journal Articles

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Michael Broux, Cristina Prieto, Sofie Demeyer, Marlies Vanden Bempt, Llucia Alberti-Servera, Inge Lodewijckx, Roel Vandepoel, Nicole Mentens, Olga Gielen, Kris Jacobs, Ellen Geerdens, Carmen Vicente, Charles E. de Bock, Jan Cools

Blood (2019) 134 (16): 1323–1336.

https://doi.org/10.1182/blood.2019000015

Published: 2019

Includes: Supplemental data

Journal Articles

Targeting BCL-2, BCL-XL, BCL-W and MDM2 in B-Cell Acute Lymphoblastic Leukemia Is Highly Effective Ex Vivo

Helena Hohtari, MD, Shady Awad, MD, Olli Dufva, Swapnil Potdar, MSc, Caroline A Heckman, PhD, Krister Wennerberg, PhD, Satu Mustjoki, MD PhD, Kimmo Porkka, MD PhD

Blood (2018) 132 (Supplement 1): 3975.

https://doi.org/10.1182/blood-2018-99-110610

Published: 2018

Journal Articles

An in Vitro Study on the Role of Angiogenesis in Iron Deficiency Induced Reactive Thrombocytosis

Pedro De Alarcon, MD, Manu Gnanamony, PhD, Jessica Garcia, MD

Blood (2018) 132 (Supplement 1): 2450.

https://doi.org/10.1182/blood-2018-99-115378

Published: 2018

Journal Articles

RUNX1 Mutations Identify an Entity of Blast Phase Chronic Myeloid Leukemia (BP-CML) Patients with Distinct Phenotype, Transcriptional Profile and Drug Vulnerabilities

Shady Awad, MD, Matti Kankainen, PhD, Olli Dufva, Caroline A Heckman, PhD, Kimmo Porkka, MD PhD, Satu Mustjoki, MD PhD

Blood (2018) 132 (Supplement 1): 4257.

https://doi.org/10.1182/blood-2018-99-111602

Published: 2018

Journal Articles

Angiogenesis Induced By Aminoacyl-tRNA Synthetase Deficiency Is Dependent on Amino Acid Response (AAR) but Not Unfolded Protein Response (UPR) Pathways

Fan Zhang, Yi Chen, Yi Jin, Chun-Hui Xu, Dian-Jia Liu, Ai-Ning Xu, Yuan-Liang Zhang, Yin-Yin Xie, Jing-Yi Shi, Lan Wang, MD, Qiu-Hua Huang, Zhu Chen, Sai-Juan Chen, Xiao-Jian Sun, PhD

Blood (2018) 132 (Supplement 1): 77.

https://doi.org/10.1182/blood-2018-99-117909

Published: 2018

Journal Articles

Preclinical Rationale for the Use of Regorafenib in Myeloid Malignancies

Gabriela S. Hobbs, MD, Andrew M. Brunner, MD, Timothy A. Graubert, MD, Cyril H Benes, Gabriel Daniel Duda, DMD, PhD, Yi-Bin Chen, MD

Blood (2017) 130 (Supplement 1): 2643.

https://doi.org/10.1182/blood.V130.Suppl_1.2643.2643

Published: 2017

Journal Articles

Induction of Arterial Type of Hemogenic Endothelium from Human Pluripotent Stem Cells

Mi Ae Park, PhD, Akhilesh Kumar, PhD, Ho Sun Jung, PhD, Gene Ueneshi, PhD, Oleg Moskvin, PhD, Scott Swanson, PhD, James A. Thomson, VMD, PhD, Igor Slukvin, MDPhD

Blood (2017) 130 (Supplement 1): 1143.

https://doi.org/10.1182/blood.V130.Suppl_1.1143.1143

Published: 2017

Journal Articles

Efficacy and Safety of Novel Targeted Drug' Apatinib in Relapse or Refractory Non-Hodgkin Lymphoma: An Open Label, Single-Armed, Exploratory Study

Ling Li, MSPH, Sa Xiao, Ken H. Young, MD PhD, Lei Zhang, MD, Xin Li, MD, Xiaorui Fu, MDPhD, Zhaoming Li, MDPhD, Zhenchang Sun, MDPhD, Xudong Zhang, MDPhD, Jiaqin Yan, MDPhD, Feifei Nan, MDPhD, Yu Chang, Mengyuan Shi, graduate student, Mingzhi Zhang

Blood (2017) 130 (Supplement 1): 1548.

https://doi.org/10.1182/blood.V130.Suppl_1.1548.1548

Published: 2017

Journal Articles

Predictive Simulation Modeling in JAK2-Mutant MPNs Identified Ruxolitinib and Sorafenib As a Synergistic Drug Combination for Disease Modifying Therapy

Peter P. Sayeski, PhD, Leylah M. Drusbosky, PhD, Neeraj Kumar Singh, B.Tech, Anusha Pampana, Shahabuddin Usmani, MS, Mohammed Sauban, BE, Abha Kushwaha, Anu Ramakrishnan, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Christopher R. Cogle, MD

Blood (2017) 130 (Supplement 1): 5287.

https://doi.org/10.1182/blood.V130.Suppl_1.5287.5287

Published: 2017

Journal Articles

Integrated Functional Genomic and Pharmacological Characterization of the Kinome of Myeloma Cells

Ricardo De Matos Simoes, PhD, Eugen Dhimolea, PhD, Ryosuke Shirasaki, MD PhD, Sara Gandolfi, MD, Geoffrey Matthews, PhD, Michal Sheffer, PhD, Olga Dashevsky, PhD, Brian Glassner, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 2501.

https://doi.org/10.1182/blood.V130.Suppl_1.2501.2501

Published: 2017

Journal Articles

Lymphangiogenesis is a feature of acute GVHD, and VEGFR-3 inhibition protects against experimental GVHD

Sarah Mertlitz, Yu Shi, Martina Kalupa, Carsten Grötzinger, Jörg Mengwasser, Katarina Riesner, Steffen Cordes, Sefer Elezkurtaj, Olaf Penack

Blood (2017) 129 (13): 1865–1875.

https://doi.org/10.1182/blood-2016-08-734210

Published: 2017

Includes: Supplemental data

Journal Articles

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Jarno Kivioja, MSc, Angeliki Thanasopoulou, PhD, Mika Kontro, MD, Bhagwan Yadav, MSc, Muntasir Mamun Majumder, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Kimmo Porkka, MD PhD, Juerg Schwaller, MD, Caroline A Heckman, PhD

Blood (2016) 128 (22): 4711.

https://doi.org/10.1182/blood.V128.22.4711.4711

Published: 2016

Journal Articles

Novel Targets Identified By in Vitro Screening of Patient Samples with Adult Acute Lymphoblastic Leukemia

Jessica T Leonard, MD, Bill H. Chang, MD PhD, Jeffrey W. Tyner, PhD, Brandon Hayes-Lattin, MD, Marc M. Loriaux, Brian J. Druker, Uma Borate, MD

Blood (2016) 128 (22): 2811.

https://doi.org/10.1182/blood.V128.22.2811.2811

Published: 2016

Journal Articles

Clinical Impact of Different Levels of VEGF-C on Leukemic Blasts in the Bone Marrow and Peripheral Blood of Acute Myeloid Leukemia

Sung-Eun Lee, Ji Yoon Lee, A-Reum Han, Woo-Sung Min, Heeje Kim

Blood (2016) 128 (22): 1670.

https://doi.org/10.1182/blood.V128.22.1670.1670

Published: 2016

Journal Articles

Lower Levels of Circulating Endothelial Progenitor Cells Are Associated with Increased Recurrence after Unprovoked Venous Thrombosis

Charlotte Ann Bradbury, PhD MD FRCPath, FRCP, MSc, Tracey Buckley, BSc, Kate Fletcher, PhD, Peter Rose, FRCP, FRCPath, David Fitzmaurice, MBChB, MRCGP, MD FRCGP

Blood (2016) 128 (22): 3805.

https://doi.org/10.1182/blood.V128.22.3805.3805

Published: 2016

NARROW

Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis

Role of Thrombopoietin in Stimulating Megakaryopoiesis of ITP Patients Via Rescuing Vascular Niche

Concurrent Treatment of VEGFR Tyrosine Kinase Inhibitors (TKIs) and Factor Xa Inhibitors Is Associated with Increased Bleeding Risks

High Serum VEGF Level in Erdheim-Chester Disease: Correlation with Cardiovascular Involvement and Response to Treatment

Genome-Wide CRISPR Screening Identifies MAPK and Mtorc Pathways As Regulators of Sorafenib Resistance in Acute Myeloid Leukemia

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Targeting BCL-2, BCL-XL, BCL-W and MDM2 in B-Cell Acute Lymphoblastic Leukemia Is Highly Effective Ex Vivo

An in Vitro Study on the Role of Angiogenesis in Iron Deficiency Induced Reactive Thrombocytosis

RUNX1 Mutations Identify an Entity of Blast Phase Chronic Myeloid Leukemia (BP-CML) Patients with Distinct Phenotype, Transcriptional Profile and Drug Vulnerabilities

Angiogenesis Induced By Aminoacyl-tRNA Synthetase Deficiency Is Dependent on Amino Acid Response (AAR) but Not Unfolded Protein Response (UPR) Pathways

Preclinical Rationale for the Use of Regorafenib in Myeloid Malignancies

Induction of Arterial Type of Hemogenic Endothelium from Human Pluripotent Stem Cells

Efficacy and Safety of Novel Targeted Drug' Apatinib in Relapse or Refractory Non-Hodgkin Lymphoma: An Open Label, Single-Armed, Exploratory Study

Predictive Simulation Modeling in JAK2-Mutant MPNs Identified Ruxolitinib and Sorafenib As a Synergistic Drug Combination for Disease Modifying Therapy

Integrated Functional Genomic and Pharmacological Characterization of the Kinome of Myeloma Cells

Lymphangiogenesis is a feature of acute GVHD, and VEGFR-3 inhibition protects against experimental GVHD

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Novel Targets Identified By in Vitro Screening of Patient Samples with Adult Acute Lymphoblastic Leukemia

Clinical Impact of Different Levels of VEGF-C on Leukemic Blasts in the Bone Marrow and Peripheral Blood of Acute Myeloid Leukemia

Lower Levels of Circulating Endothelial Progenitor Cells Are Associated with Increased Recurrence after Unprovoked Venous Thrombosis

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American Society of Hematology

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American Society of Hematology

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