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Journal Articles

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Blood (2020) 136 (1): 130–136.

https://doi.org/10.1182/blood.2019003369

Published: 2020

Includes: Supplemental data

Journal Articles

Effects of Rifaximin on Intestinal Pathophysiologic Changes Associated with Sickle Cell Disease (SCD)

Dibyendu Dutta, PhD, Seah H Lim, MD PhD

Blood (2019) 134 (Supplement_1): 2282.

https://doi.org/10.1182/blood-2019-127043

Published: 2019

Journal Articles

Alterations of Gut Microbiome Accelerate Multiple Myeloma Progression By Increasing the Relative Abundances of Nitrogen Recycling Bacteria

Xingxing Jian, PhD, Yinghong Zhu, Jian Ouyang, Qian Lei, Jiliang Xia, PhD, Jingyu Zhang, Jiaojiao Guo, Jinuo Wang, MD, Jingchao Lin, Mingming Su, Yongjun Guan, Guancheng Li, PhD, Minghua Wu, PhD, Jian Li, MD, Juanjuan Xiang, PhD, Lu Xie, PhD, Lugui Qiu, MD PhD, Wei Jia, PhD, Wen Zhou, PhD

Blood (2019) 134 (Supplement_1): 688.

https://doi.org/10.1182/blood-2019-125051

Published: 2019

Journal Articles

Autologous Transplant Recipients Have a Healthier Gut Microbiota at Baseline and Faster Recovery from Microbiome Injury Compared to Allogeneic Transplant Recipients

Rajat Bansal, MD, Heekuk Park, Cristian Taborda, Christian Gordillo, BS, Markus Y. Mapara, MD PhD, Amer Assal, MD, Anne-Catrin Uhlemann, MD, Ran Reshef, MDMSc

Blood (2019) 134 (Supplement_1): 4491.

https://doi.org/10.1182/blood-2019-129304

Published: 2019

Journal Articles

Sparing of the Lower Gastrointestinal Tract Microbiota Is Associated with Reduced Acute Graft-Versus-Host Disease

Doris M Ponce, MD, Marina D Burgos da Silva, PhD, Antonio L.C. Gomes, PhD, Gillian Moore, BA, John B. Slingerland, BSc, Eric G. Pamer, MD, Ying Taur, MD MPH, Jonathan U. Peled, MD PhD, Marcel R.M. van den Brink, MD PhD

Blood (2019) 134 (Supplement_1): 4538.

https://doi.org/10.1182/blood-2019-131067

Published: 2019

Journal Articles

Intestinal Microbiota Composition Is Associated with Minimal Residual Disease Negativity in Patients with Multiple Myeloma

Matthew J. Pianko, MD, Sean M Devlin, PhD, Eric R. Littmann, BA, Aisara Chansakul, BS, Donna Mastey, RN, Meghan Salcedo, RN, Emily Fontana, BA, Lilan Ling, BS, Elizabet Tavitian, BS, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Annelie Clurman, BA, Antonio LC Gomes, PhD, Ying Taur, MD MPH, Eric G. Pamer, MD, Jonathan U. Peled, MD PhD, Marcel R.M. van den Brink, MD PhD, Ola Landgren, MD PhD, Alexander M. Lesokhin, MD

Blood (2018) 132 (Supplement 1): 3167.

https://doi.org/10.1182/blood-2018-99-117719

Published: 2018

Journal Articles

Intestinal Enterococcus Is a Major Risk Factor for the Development of Acute Gvhd

Christoph K. Stein-Thoeringer, MD, Jonathan U. Peled, MD PhD, Antonio LC Gomes, PhD, Amina Lazrak, BS, Melissa D Docampo, BS, Ann E. Slingerland, BSc, Katherine Nichols, BS, Yusuke Shono, MD PhD, Daniela Weber, MD, Anthony D. Sung, MD, Daigo Hashimoto, MD, PhD, Justin Cross, PhD, Takanori Teshima, Ernst Holler, MD, Nelson J. Chao, MD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD

Blood (2018) 132 (Supplement 1): 358.

https://doi.org/10.1182/blood-2018-99-119887

Published: 2018

Journal Articles

Subversion of Systemic Glucose Metabolism As a Mechanism to Support the Growth of Leukemia Cells

Haobin Ye, PhD, Biniam Adane, PhD, Nabilah Khan, Mohd Minhajuddin, PhD, Brett M. Stevens, PhDBS, Daniel A Pollyea, MD, Craig T Jordan, PhD

Blood (2018) 132 (Supplement 1): 908.

https://doi.org/10.1182/blood-2018-99-117064

Published: 2018

Journal Articles

Expression of the Butyrate/Niacin Receptor, GPR109a on T Cells Plays an Important Role in a Mouse Model of Graft Versus Host Disease

Melissa D Docampo, BS, Christoph K. Stein-Thoeringer, MD, Amina Lazrak, BS, Marina D Burgos da Silva, PhD, Justin Cross, PhD, Marcel R.M. van den Brink, MD PhD

Blood (2018) 132 (Supplement 1): 61.

https://doi.org/10.1182/blood-2018-99-118783

Published: 2018

Journal Articles

Clinical Efficacy of Prebiotics on Transplant-Related Complications

Kota Yoshifuji, MD, Kyoko Inamoto, MD, Kazuhiko Kakihana, MD PhD, Megumi Akiyama, MD, Takashi Toya, MD PhD, Aiko Igarashi, MD, Yuho Najima, MD, Noriko Doki, MD PhD, Takeshi Kobayashi, MD, Yuuko Kiridooshi, Kozue Takeshita, MD PhD, Wataru Suda, Atsushi Shiota, Masahira Hattori, MD PhD, Kenya Honda, MD PhD, Hisashi Sakamaki, MD PhD, Kazuteru Ohashi, MD PhD

Blood (2018) 132 (Supplement 1): 4573.

https://doi.org/10.1182/blood-2018-99-114845

Published: 2018

Journal Articles

Oral Nutrition Modulates the Intestinal Barrier Following Cytotoxic Therapy Via the Microbiome

Zaker I. Schwabkey, MD, Diana H. Wiesnoski, Dung Pham, Christopher A. Sanchez, Chia-Chi Chang, PhD, Mohamed A. Jamal, PhD, Robert R. Jenq, MD

Blood (2018) 132 (Supplement 1): 63.

https://doi.org/10.1182/blood-2018-99-110037

Published: 2018

Journal Articles

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

Hideaki Fujiwara, MD PhD, Nathan Mathewson, PhD, Tomomi Toubai, MD PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Julia Wu, BS, Yaping Sun, MD PhD, Chen Liu, MD PhD, Pavan R. Reddy, MD

Blood (2016) 128 (22): 1157.

https://doi.org/10.1182/blood.V128.22.1157.1157

Published: 2016

Journal Articles

Intra-Patient Variability in Fetal Hemoglobin Measurements over Time in Sickle Cell Disease Patients Not on Fetal Hemoglobin Inducing Agents

Esther E Knapp, MD MBE, Deepa Manwani, MD, Abdullah Kutlar, MD, Hillel W Cohen, DrPH, MPH, Richard G. Ghalie, MD

Blood (2014) 124 (21): 4096.

https://doi.org/10.1182/blood.V124.21.4096.4096

Published: 2014

Journal Articles

Multiple Oral Therapeutics Suppress Repressors (LSD-1, HDACs, and BCL11A) of Gamma Globin Gene Expression

Yan Dai, PhD, Douglas V Faller, MD PhD, Jose I Sangerman, PhD, Suthat Fucharoen, Susan P Perrine, MD

Blood (2014) 124 (21): 2687.

https://doi.org/10.1182/blood.V124.21.2687.2687

Published: 2014

Journal Articles

Targeting The PRMT5 Enzyme To Induce γ -Globin Gene Derepression In Sickle Cell Anemia

Necrisha Roach, MSc., Matthew Cannon, Dalia El-Gamal, PhD, Payal C Desai, MD, Eric H. Kraut, MD, James E. Bradner, M.D., Rosa Lapalombella, PhD, Robert A. Baiocchi, M.D., Ph.D.

Blood (2013) 122 (21): 1007.

https://doi.org/10.1182/blood.V122.21.1007.1007

Published: 2013

Journal Articles

A Phase 2 Trial of HQK-1001 (sodium 2,2-dimethylbutyrate), an Oral Fetal Globin Gene Inducer, in HbE-Beta Thalassemia in Thailand

Suthat Fucharoen, MD, Nattawara Chaneiam, Beer Poramin Patthamalai, Susan P Perrine, MD

Blood (2012) 120 (21): 251.

https://doi.org/10.1182/blood.V120.21.251.251

Published: 2012

Journal Articles

A Randomized, Open-Label, Multicenter, Dose Escalation Study of HQK-1001 (2,2-Dimethylbutyrate, Sodium Salt) in Sickle Cell Disease

Abdullah Kutlar, MD, Marvin Reid, PhD, Ali T Taher, MD, Adlette Inati, MD, Miguel R. Abboud, MD, Amal El-Beshlawy, MD, George R. Buchanan, MD, Hedy Smith, MD PhD, Kenneth I. Ataga, MD, Nebu Koshy, MD, FACP, Lynne D Neumayr, MD, Punam Malik, M.D., Ofelia A. Alvarez, MD, Richard Ward, MBBS, MRCP, FRCPath, J Michael White, PhD, Elsa Johnson, MBA, Richard G. Ghalie, MD

Blood (2012) 120 (21): 998.

https://doi.org/10.1182/blood.V120.21.998.998

Published: 2012

Journal Articles

An Approach for Tailoring Diverse Therapeutic Inducers of Fetal Globin to Genetic Modifier Profiles,

Susan P Perrine, MD, David H.K. Chui, MD, Jose I Sangerman, PhD, Michael S Boosalis, PhD, Douglas V Faller, MD, PhD

Blood (2011) 118 (21): 3188.

https://doi.org/10.1182/blood.V118.21.3188.3188

Published: 2011

Journal Articles

Histone Deacetylase Inhibitors Induce Cell Growth Inhibition and Apoptosis in NPM1 -Mutated AML Cells: A Possible Role for Epigenetic Therapies in AML Carrying NPM1 Gene Mutations

Ilaria Gionfriddo, Federica Mezzasoma, Federica Cecchetti, Roberta Rossi, Francesca Strozzini, Francesco Di Raimondo, MD, Valentina Pettirossi, PhD, Brunangelo Falini, MD, Maria Paola Martelli, MD

Blood (2011) 118 (21): 2621.

https://doi.org/10.1182/blood.V118.21.2621.2621

Published: 2011

Journal Articles

A Phase 2 Clinical Study of HQK-1001 (2,2-dimethylbutyrate, sodium salt), a Fetal Hemoglobin Inducer, in Patients with Sickle Cell Disease

Abdullah Kutlar, MD, Adlette Inati, MD, Ali T Taher, MD, Amal El-Beshlawy, MD, Marvin Reid, PhD, Miguel R. Abboud, MD, Hedy Smith, MD, PhD, Kenneth I. Ataga, MD, George R. Buchanan, MD, Punam Malik, MD, Nebu Koshy, MD, Lynne Neumayr, MD, Maria Aiello, MA, Elsa Johnson, MBA, J Michael White, PhD, Richard G. Ghalie, MD

Blood (2011) 118 (21): 1066.

https://doi.org/10.1182/blood.V118.21.1066.1066

Published: 2011

NARROW

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Effects of Rifaximin on Intestinal Pathophysiologic Changes Associated with Sickle Cell Disease (SCD)

Alterations of Gut Microbiome Accelerate Multiple Myeloma Progression By Increasing the Relative Abundances of Nitrogen Recycling Bacteria

Autologous Transplant Recipients Have a Healthier Gut Microbiota at Baseline and Faster Recovery from Microbiome Injury Compared to Allogeneic Transplant Recipients

Sparing of the Lower Gastrointestinal Tract Microbiota Is Associated with Reduced Acute Graft-Versus-Host Disease

Intestinal Microbiota Composition Is Associated with Minimal Residual Disease Negativity in Patients with Multiple Myeloma

Intestinal Enterococcus Is a Major Risk Factor for the Development of Acute Gvhd

Subversion of Systemic Glucose Metabolism As a Mechanism to Support the Growth of Leukemia Cells

Expression of the Butyrate/Niacin Receptor, GPR109a on T Cells Plays an Important Role in a Mouse Model of Graft Versus Host Disease

Clinical Efficacy of Prebiotics on Transplant-Related Complications

Oral Nutrition Modulates the Intestinal Barrier Following Cytotoxic Therapy Via the Microbiome

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

Intra-Patient Variability in Fetal Hemoglobin Measurements over Time in Sickle Cell Disease Patients Not on Fetal Hemoglobin Inducing Agents

Multiple Oral Therapeutics Suppress Repressors (LSD-1, HDACs, and BCL11A) of Gamma Globin Gene Expression

Targeting The PRMT5 Enzyme To Induce γ -Globin Gene Derepression In Sickle Cell Anemia

A Phase 2 Trial of HQK-1001 (sodium 2,2-dimethylbutyrate), an Oral Fetal Globin Gene Inducer, in HbE-Beta Thalassemia in Thailand

A Randomized, Open-Label, Multicenter, Dose Escalation Study of HQK-1001 (2,2-Dimethylbutyrate, Sodium Salt) in Sickle Cell Disease

An Approach for Tailoring Diverse Therapeutic Inducers of Fetal Globin to Genetic Modifier Profiles,

Histone Deacetylase Inhibitors Induce Cell Growth Inhibition and Apoptosis in NPM1 -Mutated AML Cells: A Possible Role for Epigenetic Therapies in AML Carrying NPM1 Gene Mutations

A Phase 2 Clinical Study of HQK-1001 (2,2-dimethylbutyrate, sodium salt), a Fetal Hemoglobin Inducer, in Patients with Sickle Cell Disease

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American Society of Hematology

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American Society of Hematology

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