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Journal Articles

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

Claudia Morganti, PhD, Massimo Bonora, PhD, Kyoko Ito, Keisuke Ito, MD PhD

Blood (2019) 134 (Supplement_1): 1188.

https://doi.org/10.1182/blood-2019-125891

Published: 2019

Journal Articles

Aryl Hydrocarbon Receptor (AHR) Antagonism As a Transformative, Dual-Mechanism Novel Therapy for Multiple Myeloma

Taylor Gonzalez, Evan C Catton, Ashley E. Rosko, MD, Yvonne Efebera, MD, Maria Chaudhry, MD, Francesca Cottini, MD, Bethany L Mundy-Bosse, PhD, Tiffany Hughes, BS, PhD, Don M. Benson, Jr., MD PhD

Blood (2018) 132 (Supplement 1): 1933.

https://doi.org/10.1182/blood-2018-99-117465

Published: 2018

Journal Articles

Metabolomics Profiling after Allogeneic Hematopoietic Stem Cell Transplantation Unravels a Specific Signature in Human Acute GVHD

David Michonneau, MD, Eleonora Latis, Laetitia Dubouchet, Regis Peffault De Latour, Marie Robin, MD PhD, Flore Sicre De Fontbrune, MD PhD, Lars Rogge, PhD, Gerard Socie, MD PhD

Blood (2018) 132 (Supplement 1): 69.

https://doi.org/10.1182/blood-2018-99-110441

Published: 2018

Journal Articles

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Alessandra Romano, MDPhD, Laura Oliva, PhD, Jose Manuel Manteiga, Todoerti Katia, Lorenzo Canziani, Matteo Trudu, Francesca Fontana, Michela Ghizzinardi, Ugo Orfanelli, Magda Marcatti, MD, Fabio Ciceri, MD, Giovanni Tonon, MD PhD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD

Blood (2017) 130 (Supplement 1): 3051.

https://doi.org/10.1182/blood.V130.Suppl_1.3051.3051

Published: 2017

Journal Articles

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Murakami Shohei, PhD, Masayuki Yamamoto, MD PhD, Hozumi Motohashi, MD PhD

Blood (2015) 126 (23): 2351.

https://doi.org/10.1182/blood.V126.23.2351.2351

Published: 2015

Journal Articles

Quantitative Whole Body Autoradiography (QWBA) Analysis Reveals That CPX-351 Shifts the Exposure of Cytarabine (Cyt) and Daunorubicin (Daun) Away from Many Tissues While Providing Prolonged Exposure to Cytotoxic Drug Concentrations in the Bone Marrow Compared to Conventional Free Drug Administration

Lawrence D Mayer, PhD, Nicole Sadowski, Paul Tardi, PhD, Xiaowei Xie, PhD, Donna Cabral-Lilly, PhD, Dennis Heller, PhD

Blood (2014) 124 (21): 3740.

https://doi.org/10.1182/blood.V124.21.3740.3740

Published: 2014

Journal Articles

CPX-351 Markedly Reduces Renal and Hepatic Clearance Rates for Cytarabine (Cyt) and Daunorubicin (Daun) in Rats with an Associated Decrease in Excretory and Metabolic Burden Despite Providing Dramatic Increases in Systemic Drug Exposure Compared to Conventional Cyt+Daun

Lawrence D Mayer, PhD, Jeffrey Fulton, Heasook Kim-Kang, Yijun Yi, Peter Wang, Paul Tardi, PhD, Xiaowei Xi, Dennis Heller, PhD

Blood (2014) 124 (21): 2305.

https://doi.org/10.1182/blood.V124.21.2305.2305

Published: 2014

Journal Articles

Impact of Drug Transporters ABCB1 and ABCG2 and Regulators of Xenobiotic Transport and Metabolism Pxr and CAR Gene Polymorphisms on Clinical Efficacy of Imatinib in Chronic Myeloid Leukemia (CML)

Anna Stepien, MSc, Alessandro Martino, PhD, Federico Canzian, PhD, Daniele Campa, PhD, Angelika Stein, Joanna Gora-Tybor, MD PhD, Tomasz Sacha, MD PhD, Dorota Link-Lenczowska, PhD, Izabela Florek, PhD, Witold Prejzner, MD PhD, Zofia Specht-Szwoch, Malgorzata Calbecka, MD PhD, Marcin Rymko, MD PhD, Marek Dudzinski, MD PhD, Pawel Gaj, PhD, Tadeusz Robak, MD, Krzysztof Warzocha, MD PhD, Krzysztof Jamroziak, MD PhD

Blood (2014) 124 (21): 5222.

https://doi.org/10.1182/blood.V124.21.5222.5222

Published: 2014

Journal Articles

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

Christopher N Lewis, AB, Raghavan Chinnadurai, PhD, Jacques Galipeau, MD

Blood (2014) 124 (21): 1593.

https://doi.org/10.1182/blood.V124.21.1593.1593

Published: 2014

Journal Articles

PP2A inactivation by ROS accumulation

Shingo Nakahata, Kazuhiro Morishita

Blood (2014) 124 (14): 2163–2165.

https://doi.org/10.1182/blood-2014-08-594093

Published: 2014

Journal Articles

Hematology from the Ground Up: Lessons from C. elegans

Iqbal Hamza, PhD

Blood (2013) 122 (21): SCI-16.

https://doi.org/10.1182/blood.V122.21.SCI-16.SCI-16

Published: 2013

Journal Articles

Aryl Hydrocarbon Receptor Deficient Donor T Cells Display Decreased Migration and Cause Reduced Or Enhanced Graft-Versus-Host Diseases In Different Transplant Models

Kaifeng Lisa Lin, PhD, LeShara M Fulton, Ph.D., Jonathan Serody, MD

Blood (2013) 122 (21): 4477.

https://doi.org/10.1182/blood.V122.21.4477.4477

Published: 2013

Journal Articles

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

Stephanie McGregor, MD, PhD, Anant Shah, Gordana Raca, Kamran Mirza, MD PHD, John Anastasi, MD, James W. Vardiman, MD, Elizabeth Hyjek, MD, PhD, Sandeep Gurbuxani, MBBS, PhD

Blood (2013) 122 (21): 4300.

https://doi.org/10.1182/blood.V122.21.4300.4300

Published: 2013

Journal Articles

A New Form Of Therapeutic Resistance: Drug Glucuronidation Regulated By The Sonic Hedgehog Factor Gli1

Hiba A Zahreddine, Biljana Culjkovic-Kraljacic, PhD, Sarit Assouline, MD, Abdellatif Amri, Patrick Gendron, M.Sc., Andrea A. Romeo, PhD, Stephen Morris, PhD, James Jaquith, PhD, Gregory Cormack, Eftihia Cocolakis, PhD, Julie Bergeron, MD, Leandro Cerchietti, MD, Brian Leber, MD, Wilson H. Miller, Jr., MD, PhD, Katherine LB. Borden, PhD

Blood (2013) 122 (21): 821.

https://doi.org/10.1182/blood.V122.21.821.821

Published: 2013

Journal Articles

A Genome-Wide Association Study (GWAS) Of Event-Free Survival In Diffuse Large B-Cell Lymphoma (DLBCL) Treated With Rituximab and Anthracycline-Based Chemotherapy: A Lysa and Iowa/Mayo Clinic SPORE Multistage Study

Blood (2013) 122 (21): 76.

https://doi.org/10.1182/blood.V122.21.76.76

Published: 2013

Journal Articles

In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells

Jennifer L Gori, PhD, Jason M Butler, PhD, Devikha Chandrasekaran, MS, Brian C Beard, PhD, Daniel J Nolan, PhD, Michael Ginsberg, PhD, Jennifer E Adair, PhD, Shahin Rafii, MD, Hans-Peter Kiem, MD

Blood (2013) 122 (21): 466.

https://doi.org/10.1182/blood.V122.21.466.466

Published: 2013

Journal Articles

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Michaela Gruber, Judith Bellemare, Gregor Hoermann, Andreas Gleiss, Edit Porpaczy, Martin Bilban, Trang Le, Sonja Zehetmayer, Christine Mannhalter, Alexander Gaiger, Medhat Shehata, Karin Fleiss, Cathrin Skrabs, Éric Lévesque, Katrina Vanura, Chantal Guillemette, Ulrich Jaeger

Blood (2013) 121 (7): 1175–1183.

https://doi.org/10.1182/blood-2012-08-447359

Published: 2013

Includes: Supplemental data

Journal Articles

Organic Anion Transporting Polypeptide 1B (OATP1B) Transporters Modulate Hydroxyurea Pharmacokinetics

Aisha L. Walker, PhD, Cynthia S Lancaster, PhD, Russell E. Ware, MD, PhD, Alex Sparreboom, PhD

Blood (2012) 120 (21): 1008.

https://doi.org/10.1182/blood.V120.21.1008.1008

Published: 2012

Journal Articles

Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients.

Peter P. Ruvolo, PhD, Rodrigo Jacamo, PhD, Teresa McQueen, BS, Rongqing Pan, BS, Ismael Samudio, PhD, Marina Konopleva, MD, PhD, Steven M. Kornblau, MD, Ramiro Garzon, MD, Carlo M. Croce, MD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 2354.

https://doi.org/10.1182/blood.V120.21.2354.2354

Published: 2012

Journal Articles

Nrf2 Deficiency Leads to Altered Hematopoietic Stem Cell Function and Increased Sensitivity to Alkylating Agent Induced Myeloid Dysplasia,

Liang Li, PhD, Yin Wei Ho, Qin Huang, MD, PhD, Min Li, PhD, Stephen J. Forman, MD, Smita Bhatia, MD, MPH, Ravi Bhatia, MD

Blood (2011) 118 (21): 3828.

https://doi.org/10.1182/blood.V118.21.3828.3828

Published: 2011

NARROW

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

Aryl Hydrocarbon Receptor (AHR) Antagonism As a Transformative, Dual-Mechanism Novel Therapy for Multiple Myeloma

Metabolomics Profiling after Allogeneic Hematopoietic Stem Cell Transplantation Unravels a Specific Signature in Human Acute GVHD

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Quantitative Whole Body Autoradiography (QWBA) Analysis Reveals That CPX-351 Shifts the Exposure of Cytarabine (Cyt) and Daunorubicin (Daun) Away from Many Tissues While Providing Prolonged Exposure to Cytotoxic Drug Concentrations in the Bone Marrow Compared to Conventional Free Drug Administration

CPX-351 Markedly Reduces Renal and Hepatic Clearance Rates for Cytarabine (Cyt) and Daunorubicin (Daun) in Rats with an Associated Decrease in Excretory and Metabolic Burden Despite Providing Dramatic Increases in Systemic Drug Exposure Compared to Conventional Cyt+Daun

Impact of Drug Transporters ABCB1 and ABCG2 and Regulators of Xenobiotic Transport and Metabolism Pxr and CAR Gene Polymorphisms on Clinical Efficacy of Imatinib in Chronic Myeloid Leukemia (CML)

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

PP2A inactivation by ROS accumulation

Hematology from the Ground Up: Lessons from C. elegans

Aryl Hydrocarbon Receptor Deficient Donor T Cells Display Decreased Migration and Cause Reduced Or Enhanced Graft-Versus-Host Diseases In Different Transplant Models

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

A New Form Of Therapeutic Resistance: Drug Glucuronidation Regulated By The Sonic Hedgehog Factor Gli1

A Genome-Wide Association Study (GWAS) Of Event-Free Survival In Diffuse Large B-Cell Lymphoma (DLBCL) Treated With Rituximab and Anthracycline-Based Chemotherapy: A Lysa and Iowa/Mayo Clinic SPORE Multistage Study

In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Organic Anion Transporting Polypeptide 1B (OATP1B) Transporters Modulate Hydroxyurea Pharmacokinetics

Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients.

Nrf2 Deficiency Leads to Altered Hematopoietic Stem Cell Function and Increased Sensitivity to Alkylating Agent Induced Myeloid Dysplasia,

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American Society of Hematology

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American Society of Hematology

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