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Journal Articles

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

Blood (2021) 137 (18): 2481–2494.

https://doi.org/10.1182/blood.2020005627

Published: 2021

Includes: Supplemental data

Journal Articles

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Michaela Gruber, Judith Bellemare, Gregor Hoermann, Andreas Gleiss, Edit Porpaczy, Martin Bilban, Trang Le, Sonja Zehetmayer, Christine Mannhalter, Alexander Gaiger, Medhat Shehata, Karin Fleiss, Cathrin Skrabs, Éric Lévesque, Katrina Vanura, Chantal Guillemette, Ulrich Jaeger

Blood (2013) 121 (7): 1175–1183.

https://doi.org/10.1182/blood-2012-08-447359

Published: 2013

Includes: Supplemental data

Journal Articles

Efficacy of PRT060318, a Novel Highly Specific SYK Inhibitor, in Acute Lymphoblastic Leukemia (ALL)

Stefan KÖhrer, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y Rosin, PhD, Uma Sinha, PhD, Anjali Pandey, PhD, Medhat Shehata, Ulrich Jäger, Susan M. O'Brien, MD, William G. Wierda, MD, Ph.D., Zeev Estrov, MD, PhD, Deborah Thomas, MD, Hagop M Kantarjian, Jan A. Burger, MD, PhD

Blood (2012) 120 (21): 3532.

https://doi.org/10.1182/blood.V120.21.3532.3532

Published: 2012

Journal Articles

Differential Expression and Functions of NOTCH Family Members and Involvement of NR4A1 in the Regulation of Apoptosis in CLL

Rainer Hubmann, Martin Hilgarth, Susanne Schnabl, Elena Ponath, Dita Demirtas, Marlies Reiter, Ulrich Jäger, Medhat Shehata

Blood (2012) 120 (21): 3919.

https://doi.org/10.1182/blood.V120.21.3919.3919

Published: 2012

Journal Articles

Green Tea Extract EGCG Induces Apoptosis in CLL Cells and Overcomes the Supportive Effect of Primary Bone Marrow Stromal Cells Through the Regulation of PI3K/Akt Cascade and Proteasome Activity

Elena Ponath, Susanne Schnabl, Martin Hilgarth, Dita Demirtas, Marlies Reiter, Eva Fuchs, Rainer Hubmann, Ulrich Jäger, Medhat Shehata

Blood (2012) 120 (21): 3916.

https://doi.org/10.1182/blood.V120.21.3916.3916

Published: 2012

Journal Articles

Inhibition of NOTCH Activity by GLIOTOXIN Induces Apoptosis in CLL Cells and Overcomes the Supportive Effect of Primary Bone Marrow Stromal Cells

Rainer Hubmann, Martin Hilgarth, Susanne Schnabl, Elena Ponath, Dita Demirtas, Marlies Reiter, Christoph Zielinski, Ulrich Jäger, Medhat Shehata

Blood (2011) 118 (21): 4609.

https://doi.org/10.1182/blood.V118.21.4609.4609

Published: 2011

Journal Articles

Partial Characterization and In Vitro Expansion of Putative CLL Precursor/Stem Cells Which Are Dependent on Bone Marrow Microenvironment for Survival

Medhat Shehata, Rainer Hubmann, Martin Hilgarth, Susanne Schnabl, Dita Demirtas, Elina Ponath, Ekaterina Brynzak, Sabine Strommer, Volker Wachek, Alexander Hauswirth, Berthold Streubel, M.D., Katrina Vanura, Josef Schwarzmeier, Alexander Gaiger, MD, Christoph Zielinski, Peter Valent, Ulrich Jaeger

Blood (2010) 116 (21): 2433.

https://doi.org/10.1182/blood.V116.21.2433.2433

Published: 2010

Journal Articles

Expression of Lipoprotein Lipase In Chronic Lymphocytic Leukemia Cells: Is There a Biological Function?

Edit anna Porpaczy, MD, Stefanie Tauber, Martin Bilban, Gerhard Kostner, Michaela Gruber, Trang Le, Karin Fleiss, Cathrine Skrabs, Christine Einberger, Medhat Shehata, Ulrich Jaeger, Katrina Vanura

Blood (2010) 116 (21): 3580.

https://doi.org/10.1182/blood.V116.21.3580.3580

Published: 2010

Journal Articles

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Medhat Shehata, Susanne Schnabl, Dita Demirtas, Martin Hilgarth, Rainer Hubmann, Elena Ponath, Sigrun Badrnya, Claudia Lehner, Andrea Hoelbl, Markus Duechler, Alexander Gaiger, Christoph Zielinski, Josef D. Schwarzmeier, Ulrich Jaeger

Blood (2010) 116 (14): 2513–2521.

https://doi.org/10.1182/blood-2009-10-248054

Published: 2010

Includes: Supplemental data

Journal Articles

Lumiliximab Triggers Apoptosis Mechanisms in CLL Cells through the Inhibition of PI3-K/Akt Pathway.

Medhat Shehata, Susanne Schnabl, Elena Ponath, Stefanie Tauber, Dita Demirtas, Martin Hilgarth, Martin Bilban, Sigrun Badrnya, Karin Fleiss, Josef D. Schwarzmeier, Alexander Gaiger, Rainer Hubmann, Christoph C Zielinski, Steve Hughes, Ann Maclaren, Ulrich Jaeger

Blood (2009) 114 (22): 2371.

https://doi.org/10.1182/blood.V114.22.2371.2371

Published: 2009

Journal Articles

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

Antonina V. Kurtova, Kumudha Balakrishnan, Rong Chen, Wei Ding, Susanne Schnabl, Maite P. Quiroga, Mariela Sivina, William G. Wierda, Zeev Estrov, Michael J. Keating, Medhat Shehata, Ulrich Jäger, Varsha Gandhi, Neil E. Kay, William Plunkett, Jan A. Burger

Blood (2009) 114 (20): 4441–4450.

https://doi.org/10.1182/blood-2009-07-233718

Published: 2009

Includes: Supplemental data

Journal Articles

Effective Targeting of the PI3-K Pathway in CLL with NVP-BEZ235, a Novel Orally Available Dual PI3K/mTOR Inhibitor

Medhat Shehata, Susanne Schnabl, Dita Demirtas, Stefanie Tauber, Martin Hilgarth, Martin Bilban, Katrina Vanura, Edit Porpaczy, Christa Fonatsch, Stephan Stilgenbauer, MD, PhD, Josef D. Schwarzmeier, Rainer Hubmann, Alexander Gaiger, Christoph Zielinski, MD, Sauveur-Michel Maira, Carlos Garcia-Echeverria, Wolfgang Hackl, Ulrich Jaeger

Blood (2008) 112 (11): 3166.

https://doi.org/10.1182/blood.V112.11.3166.3166

Published: 2008

Journal Articles

Identification of Heat Shock Protein 32 (Hsp32) as a Novel Target in Acute Lymphoblastic Leukemia (ALL).

Renata A. Meyer, MD, Harald Herrmann, MD, Karoline V. Gleixner, MD, Alexander Gruze, Sabine Cerny-Reiterer, MD, Rainer Hubmann, PhD, Medhat Shehata, MD, Matthias Mayerhofer, MD, Wolfgang R. Sperr, MD, Winfried F. Pickl, MD, Junia V. Melo, PhD, Gahininath Y. Bharate, Ulrich Jäger, MD, Hiroshi Maeda, MD, PhD, Peter Valent, MD

Blood (2008) 112 (11): 1616.

https://doi.org/10.1182/blood.V112.11.1616.1616

Published: 2008

Journal Articles

Identification of Genes Associated with Resistance and Response in Vivo to Therapy with Rituximab, Fludarabine and Cyclophosphamide in Patients with Chronic Lymphocytic Leukemia.

Blood (2008) 112 (11): 1622.

https://doi.org/10.1182/blood.V112.11.1622.1622

Published: 2008

Journal Articles

Gene Expression Signature of B-Cell Chronic Lymphocytic Leukemia with Trisomy 12.

Blood (2007) 110 (11): 2079.

https://doi.org/10.1182/blood.V110.11.2079.2079

Published: 2007

Journal Articles

Autoimmune or Chronic Infectious Disease in B-CLL at Diagnosis: Association with Unmutated VH Gene Status and Unfavorable Cytogenetics.

Katrina Vanura, Trang Le, Harald Esterbauer, Florentin Spaeth, Edith Porpaczy, Medhat Shehata, Karin Eigenberger, Alexander Hauswirth, Cathrin Scrabs, Elisabeth Kroemer, Ilse Schwarzinger, Berthold Streubel, Christa Fonatsch, Stephan Stilgenbauer, Alexander Gaiger, Ulrich Jaeger

Blood (2007) 110 (11): 3092.

https://doi.org/10.1182/blood.V110.11.3092.3092

Published: 2007

Journal Articles

Regulation and Function of NOTCH2 in B-CLL Cells.

Rainer Hubmann, PhD, Martin Hilgarth, Susanne Schnabl, Dita Demirtas, MD, Josef D. Schwarzmeier, MD, Ulrich Jaeger, MD, Medhat Shehata, MD

Blood (2007) 110 (11): 1138.

https://doi.org/10.1182/blood.V110.11.1138.1138

Published: 2007

Journal Articles

Regulation of NOTCH2 Signaling in B-CLL: Involvement of PKC-δ.

Rainer Hubmann, PhD, Markus Duechler, PhD, Martin Hilgarth, Susanne Schnabl, Dita Demirtas, MD, Josef D. Schwarzmeier, MD, Ulrich Jaeger, MD, Medhat Shehata, MD

Blood (2006) 108 (11): 1440.

https://doi.org/10.1182/blood.V108.11.1440.1440

Published: 2006

Journal Articles

Lymphoid Microenvironment Inhibits Apoptosis in B-CLL Cells: Involvement of PI3-K/AKT Pathway and PTEN.

Medhat Shehata, MD, Susanne Schnabl, Dita Demirtas, MD, Josef D. Schwarzmeier, MD, Martin Hilgarth, Markus Duechler, PhD, Alexander Gaiger, MD, Rainer Hubmann, PhD, Ulrich Jaeger, MD

Blood (2006) 108 (11): 1443.

https://doi.org/10.1182/blood.V108.11.1443.1443

Published: 2006

Journal Articles

Anti-CD20 and Anti-CD52 Monoclonal Antibodies Enhance Cytotoxicity of Bortezomib Against Chronic Lymphocytic Leukemia Cells.

Piotr Smolewski, MD, PhD, Markus Duechler, PhD, Anna Linke, Barbara Cebula, Olga Grzybowska-Izydorczyk, MD, Medhat Shehata, MD, PhD, Tadeusz Robak, MD, PhD

Blood (2005) 106 (11): 2972.

https://doi.org/10.1182/blood.V106.11.2972.2972

Published: 2005

NARROW

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Efficacy of PRT060318, a Novel Highly Specific SYK Inhibitor, in Acute Lymphoblastic Leukemia (ALL)

Differential Expression and Functions of NOTCH Family Members and Involvement of NR4A1 in the Regulation of Apoptosis in CLL

Green Tea Extract EGCG Induces Apoptosis in CLL Cells and Overcomes the Supportive Effect of Primary Bone Marrow Stromal Cells Through the Regulation of PI3K/Akt Cascade and Proteasome Activity

Inhibition of NOTCH Activity by GLIOTOXIN Induces Apoptosis in CLL Cells and Overcomes the Supportive Effect of Primary Bone Marrow Stromal Cells

Partial Characterization and In Vitro Expansion of Putative CLL Precursor/Stem Cells Which Are Dependent on Bone Marrow Microenvironment for Survival

Expression of Lipoprotein Lipase In Chronic Lymphocytic Leukemia Cells: Is There a Biological Function?

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Lumiliximab Triggers Apoptosis Mechanisms in CLL Cells through the Inhibition of PI3-K/Akt Pathway.

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

Effective Targeting of the PI3-K Pathway in CLL with NVP-BEZ235, a Novel Orally Available Dual PI3K/mTOR Inhibitor

Identification of Heat Shock Protein 32 (Hsp32) as a Novel Target in Acute Lymphoblastic Leukemia (ALL).

Identification of Genes Associated with Resistance and Response in Vivo to Therapy with Rituximab, Fludarabine and Cyclophosphamide in Patients with Chronic Lymphocytic Leukemia.

Gene Expression Signature of B-Cell Chronic Lymphocytic Leukemia with Trisomy 12.

Autoimmune or Chronic Infectious Disease in B-CLL at Diagnosis: Association with Unmutated VH Gene Status and Unfavorable Cytogenetics.

Regulation and Function of NOTCH2 in B-CLL Cells.

Regulation of NOTCH2 Signaling in B-CLL: Involvement of PKC-δ.

Lymphoid Microenvironment Inhibits Apoptosis in B-CLL Cells: Involvement of PI3-K/AKT Pathway and PTEN.

Anti-CD20 and Anti-CD52 Monoclonal Antibodies Enhance Cytotoxicity of Bortezomib Against Chronic Lymphocytic Leukemia Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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