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Marek Mraz
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Journal Articles

5′-UTR mRNA splicing determines CD20 levels

Marek Mraz
Journal: Blood
Blood (2023) 142 (20): 1676–1678.
https://doi.org/10.1182/blood.2023022305
Published: 2023
Journal Articles

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja, Gabriela Mladonicka Pavlasova, Daniel Zicha, Marie Kudlickova Peskova, Jan Krivanek, Kvetoslava Liskova, Leos Kren, Vladimir Benes, Katerina Musilova Litzmanova, Marek Borsky, Jan Oppelt, Jan Verner, Sarka Pospisilova, Yvona Brychtova, Anna Panovska, Zhi Tan, Shuxing Zhang, Michael Doubek, Katerina Amruz Cerna, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2021) 138 (9): 758–772.
https://doi.org/10.1182/blood.2020008101
Published: 2021
Includes: Supplemental data
Journal Articles

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

Sonali Sharma, Gabriela Mladonicka Pavlasova, Vaclav Seda, Katerina Amruz Cerna, Eva Vojackova, Daniel Filip, Laura Ondrisova, Veronika Sandova, Lenka Kostalova, Pedro F. Zeni, Marek Borsky, Jan Oppelt, Kvetoslava Liskova, Leos Kren, Andrea Janikova, Sarka Pospisilova, Stacey M. Fernandes, Medhat Shehata, Laura Z. Rassenti, Ulrich Jaeger, Michael Doubek, Matthew S. Davids, Jennifer R. Brown, Jiri Mayer, Thomas J. Kipps, Marek Mraz
Journal: Blood
Blood (2021) 137 (18): 2481–2494.
https://doi.org/10.1182/blood.2020005627
Published: 2021
Includes: Supplemental data
Journal Articles

High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade during Ibrutinib Therapy in CLL Patients

Giorgia Chiodin, David Dutton, MD, Enrica Antonia Martino, MD, Samantha Drennan, PhD, Ian Tracy, PhD, Laura Ondrisova, Isla Henderson, Annalisa D'Avola, PhD, Christina Pitsillidou, Marek Mraz, MD, Peter Johnson, MDFRCP, Andrew Duncombe, MD, Graham Packham, PhD, Andrew J Steele, PhD, Helen Parker, PhD, Silvia Bonfiglio, Lydia Scarfo, MD, Lesley-Ann Sutton, Paolo Ghia, MD PhD, Matthew John Jerome Rose-Zerilli, PhD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 1752.
https://doi.org/10.1182/blood-2019-128899
Published: 2019
Journal Articles

Analysis of Mutational Landscape in Systemic Anaplastic Large Cell Lymphoma Identifies Novel Prognostic Markers

Cosimo Lobello, MSc, Boris Tichý, MD., Vojtěch Bystrý, Lenka Radova, PhD, Daniel Filip, Marek Mraz, MD, Ivonne Aidee Montes Mojarro, Falko Fend, MD, Nina Prokoph, Hugo Larose, Suzanne Turner, PhD, Huan-Chang Liang, Olaf Merkel, PhD, Kateřina Kamarádová, David Belada, MD PhD, Geeta G Sharma, PhD, Luca Mologni, PhD, Carlo Gambacorti-Passerini, MD, Andrea Janikova, MD PhD Assoc Prof, Sarka Pospisilova, Prof PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1490.
https://doi.org/10.1182/blood-2019-126501
Published: 2019
Journal Articles

miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels

Katerina Musilova, Jan Devan, Katerina Cerna, Vaclav Seda, Gabriela Pavlasova, Sonali Sharma, Jan Oppelt, Robert Pytlik, Vit Prochazka, Zuzana Prouzova, Martin Trbusek, Lenka Zlamalikova, Kvetoslava Liskova, Lenka Kruzova, Marie Jarosova, Andrea Mareckova, Christoph Kornauth, Ingrid Simonitsch-Klupp, Ana-Iris Schiefer, Olaf Merkel, Heidi Mocikova, Pavel Burda, Katerina Machova Polakova, Leos Kren, Jiri Mayer, Clive S. Zent, Marek Trneny, Andrew G. Evans, Andrea Janikova, Marek Mraz
Journal: Blood
Blood (2018) 132 (22): 2389–2400.
https://doi.org/10.1182/blood-2018-06-855502
Published: 2018
Includes: Supplemental data
Journal Articles

Rituximab Preferentially Eliminates BCR Signaling Proficient Chronic Lymphocytic Leukemia B Cells In Vivo

Gabriela Pavlasova, Marek Borsky, Katerina Musilova, Vaclav Seda, Katerina Cerna, Jitka Osickova, Eva Vojackova, Yvona Brychtova, Michael Doubek, Sarka Pospisilova, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2016) 128 (22): 2030.
https://doi.org/10.1182/blood.V128.22.2030.2030
Published: 2016
Journal Articles

The Role of Microrna-150 in the Prognosis and Transformation of Follicular Lymphoma

Katerina Musilova, Gabriela Pavlasova, Vaclav Seda, Eva Vojackova, Katerina Cerna, Jana Didi, Robert Pytlik, Vit Prochazka, Zuzana Prouzova, Lenka Zlamalikova, Sarka Pospisilova, Andrew Evans, Clive S Zent, MD, Leos Kren, Marek Trneny, Jiri Mayer, Andrea Janikova, Marek Mraz
Journal: Blood
Blood (2016) 128 (22): 4125.
https://doi.org/10.1182/blood.V128.22.4125.4125
Published: 2016
Journal Articles

Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis

Brief Report
Gabriela Pavlasova, Marek Borsky, Vaclav Seda, Katerina Cerna, Jitka Osickova, Michael Doubek, Jiri Mayer, Raffaele Calogero, Martin Trbusek, Sarka Pospisilova, Matthew S. Davids, Thomas J. Kipps, Jennifer R. Brown, Marek Mraz
Journal: Blood
Blood (2016) 128 (12): 1609–1613.
https://doi.org/10.1182/blood-2016-04-709519
Published: 2016
Includes: Supplemental data
Journal Articles

Microenvironmental Interactions up-Regulate CD20 Expression in CLL B Cells through the CXCR4/SDF-1 Axis: Implications for CD20-Targeting Antibodies and the Use of BCR-Inhibitors in Combination

Gabriela Pavlasova, MSc, Vaclav Seda, MSc, Marek Borsky, MSc., Katerina Cerna, MSc, Jitka Osickova, PhD, Jiri Mayer, Prof., MD, Sarka Pospisilova, Matthew S. Davids, MD, Jennifer R. Brown, MD PhD, Marek Mraz, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4124.
https://doi.org/10.1182/blood.V126.23.4124.4124
Published: 2015
Journal Articles

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Bing Cui, Liguang Chen, Suping Zhang, Marek Mraz, Jessie-F. Fecteau, Jian Yu, Emanuela M. Ghia, Ling Zhang, Lei Bao, Laura Z. Rassenti, Karen Messer, George A. Calin, Carlo M. Croce, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (4): 546–554.
https://doi.org/10.1182/blood-2014-03-559690
Published: 2014
Includes: Supplemental data
Journal Articles

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1

Marek Mraz, Liguang Chen, Laura Z. Rassenti, Emanuela M. Ghia, Hongying Li, Kristen Jepsen, Erin N. Smith, Karen Messer, Kelly A. Frazer, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (1): 84–95.
https://doi.org/10.1182/blood-2013-09-527234
Published: 2014
Includes: Supplemental data
Journal Articles

Ofatumumab Added To Dexamethasone In Patients With Relapsed Or Refractory Chronic Lymphocytic Leukemia. Results From a Phase II Study Of The Czech Leukemia Study Group For Life

Michael Doubek, Yvona Brychtova, MD, PhD, Anna Panovska, MD, Jakub Trizuljak, MD, Ludmila Sebejova, Olga Stehlikova, MSc., Jana Chovancova, DVM, Jitka Malcikova, PhD, Jana Smardova, MD, PhD, Karla Plevova, MSc., Pavlina Volfova, MSc., Martin Trbusek, PhD, Marek Mraz, MD, PhD, Denisa Majercakova, MD, Petra Obrtlikova, MD, Josef Karban, MD, Lukas Smolej, MD, PhD, Michaela Lindtnerova, MD, Alexandra Oltova, MD, Eva Jelinkova, MSc., Sarka Pospisilova, Jiri Mayer, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2877.
https://doi.org/10.1182/blood.V122.21.2877.2877
Published: 2013
Journal Articles

SF3B1 Mutations Frequently Occur With Both ATM Mutations and TP53 Mutations In CLL Patients

Veronika Navrkalova, MSc., Jitka Malcikova, PhD, Barbara Kantorova, MSc., Ludmila Sebejova, Karla Plevova, MSc., Marek Mraz, MD, PhD, Michael Doubek, Yvona Brychtova, MD, PhD, Jana Smardova, MD, PhD, Jiri Mayer, MD, PhD, Sarka Pospisilova, Martin Trbusek, PhD
Journal: Blood
Blood (2013) 122 (21): 2868.
https://doi.org/10.1182/blood.V122.21.2868.2868
Published: 2013
Journal Articles

Microrna-34a As a Marker for Fludarabine Resistance and Impairment of p53-Pathway in Chronic Lymphocytic Leukemia

Marek Mraz, MD, PhD, Katerina Cerna, Veronika Mayerova, Katerina Musilova, Karla Plevova, Sarka Pavlova, PhD, Boris Tichy, Dr., PhD., Michael Doubek, M.D., PhD., Prof., Yvona Brychtova, M.D., Ph.D., Jitka Malcikova, Dr, PhD, Jiri Mayer, M.D., PhD., Prof., Martin Trbusek, PhD, Sarka Pospisilova, Dr, PhD
Journal: Blood
Blood (2012) 120 (21): 3883.
https://doi.org/10.1182/blood.V120.21.3883.3883
Published: 2012
Journal Articles

Sequence Variations in miRNA Genes Are Common and May Affect Their Expression in Patients with Chronic Lymphocytic Leukemia

Jana Kminkova, PharmD., Marek Mraz, MD, PhD, Veronika Navrkalova, MSc., Boris Tichy, Dr., PhD., Jitka Malcikova, Dr., PhD., Karla Plevova, Vladimir Benes, Tobias Rausch, PhD, Yvona Brychtova, M.D., Ph.D., Michael Doubek, M.D., PhD., Prof., Jiri Mayer, M.D., PhD., Prof., Sarka Pospisilova, Dr., PhD, Prof.
Journal: Blood
Blood (2012) 120 (21): 3895.
https://doi.org/10.1182/blood.V120.21.3895.3895
Published: 2012
Journal Articles

The Target Genes and Prognostic Significance of Mir-150 in Chronic Lymphocytic Leukemia

Marek Mraz, MD, PhD, Laura Z. Rassenti, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Jessie-Farah Fecteau, Ph.D., Sarka Pospisilova, Dr, PhD, Hongying Li, PhD, Karen Messer, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3859.
https://doi.org/10.1182/blood.V120.21.3859.3859
Published: 2012
Journal Articles

Assessment of p53 Functionality in Chronic Lymphocytic Leukemia by Different Assays; An Eric-Wide Approach.

Doreen te Raa, MD, Jitka Malcikova, Dr, PhD, Marek Mraz, Sarka Pospisilova, PhD, Magali Le Garff-Tavernier, Helene Merle-Beral, MD, PhD, Tatjana Stankovic, MD., PhD, Marinus H. J. van Oers, MD PhD, Eric Eldering, PhD, Stephan Stilgenbauer, MD, Thorsten Zenz, MD, PhD, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2012) 120 (21): 2872.
https://doi.org/10.1182/blood.V120.21.2872.2872
Published: 2012
Journal Articles

MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia

Brief Report
Marek Mraz, Dasa Dolezalova, Karla Plevova, Katerina Stano Kozubik, Veronika Mayerova, Katerina Cerna, Katerina Musilova, Boris Tichy, Sarka Pavlova, Marek Borsky, Jan Verner, Michael Doubek, Yvona Brychtova, Martin Trbusek, Ales Hampl, Jiri Mayer, Sarka Pospisilova
Journal: Blood
Blood (2012) 119 (9): 2110–2113.
https://doi.org/10.1182/blood-2011-11-394874
Published: 2012
Includes: Supplemental data
Journal Articles

Mutational Analysis of Mir-29 Family Members in Chronic Lymphocytic Leukemia

Jana Lochmanova, PharmD, Marek Mraz, MD, Veronika Navrkalova, Barbora Dvorakova, Boris Tichy, Dr, Karla Plevova, Ludmila Sebejova, Dr, Jitka Malcikova, Dr, Sarka Pavlova, PhD, Vladimir Benes, Tobias Rausch, Dr, Yvona Brychtova, MD, Michael Doubek, MD, PhD, Martin Trbusek, PhD, Jiri Mayer, Sarka Pospisilova, Dr
Journal: Blood
Blood (2011) 118 (21): 1770.
https://doi.org/10.1182/blood.V118.21.1770.1770
Published: 2011