1-20 of 21
Bing Cui
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia

Clinical Trials & Observations
Bing Cui, Emanuela M. Ghia, Liguang Chen, Laura Z. Rassenti, Christopher DeBoever, George F. Widhopf, II, Jian Yu, Donna S. Neuberg, William G. Wierda, Kanti R. Rai, Neil E. Kay, Jennifer R. Brown, Jeffrey A. Jones, John G. Gribben, Kelly A. Frazer, Thomas J. Kipps
Journal: Blood
Blood (2016) 128 (25): 2931–2940.
https://doi.org/10.1182/blood-2016-04-712562
Published: 2016
Includes: Supplemental data
Journal Articles

Cirmtuzumab Targets ROR1 to Inhibit Ibrutinib-Resistant, Wnt5a-Induced Rac1 Activation in Chronic Lymphocytic Leukemia

Jian Yu, PhD, Liguang Chen, PhD, Bing Cui, PhD, Christina Wu, PhD, Michael Y. Choi, MD, Yun Chen, PhD, Ling Zhang, Laura Z. Rassenti, PhD, George F. Widhopf, II, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 2034.
https://doi.org/10.1182/blood.V128.22.2034.2034
Published: 2016
Journal Articles

Wnt5a Induces ROR1 to Complex with HS1, Which Undergoes Tyrosine Phosphorylation and Contributes to Planar-Cell-Polarity Migration in Chronic Lymphocytic Leukemia

Md Kamrul Hasan, PhD, Jian Yu, PhD, Liguang Chen, PhD, Bing Cui, PhD, Zhouxin Shen, PhD, George F. Widhopf, II, PhD, Laura Z. Rassenti, PhD, Steven P. Briggs, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 301.
https://doi.org/10.1182/blood.V128.22.301.301
Published: 2016
Journal Articles

Structural Features of ROR1 Required for Complexing with ROR2 and Enhancing Chemokine-Induced Migration and Leukemia-Cell Proliferation, Which Can be Blocked By the Anti-ROR1 Mab Cirmtuzumab (UC-961)

Jian Yu, PhD, Liguang Chen, MD PhD, George F. Widhopf, II, PhD, Suping Zhang, PhD, Bing Cui, PhD, Rongrong Wu, PhD, Ling Zhang, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1741.
https://doi.org/10.1182/blood.V126.23.1741.1741
Published: 2015
Journal Articles

High-Level Expression of ROR1 Associates with Early Disease Progression in Patients with Chronic Lymphocytic Leukemia

Bing Cui, PhD, Liguang Chen, MD PhD, Laura Z. Rassenti, PhD, Emanuela M. Ghia, PhD, Jian Yu, PhD, Ling Zhang, PhD, Donna S Neuberg, ScD, William Wierda, MD PhD, Michael Keating, MBBS, Kanti R. Rai, MD, Neil E. Kay, MD, Jennifer R. Brown, MD PhD, John C. Byrd, MD, John Gribben, MDDSc, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1713.
https://doi.org/10.1182/blood.V126.23.1713.1713
Published: 2015
Journal Articles

ROR1 Negative Chronic Lymphocytic Leukemia (CLL) Have a Distinctive Gene Expression Signature and May Represent an Indolent-Disease Subtype

Emanuela M. Ghia, PhD, Laura Z. Rassenti, PhD, Liguang Chen, MD PhD, Bing Cui, PhD, Christopher Deboever, BS, Kelly A. Frazer, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2932.
https://doi.org/10.1182/blood.V126.23.2932.2932
Published: 2015
Journal Articles

Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21 WAF1/Cip1 -dependent mechanism independent of functional p53

Jessie-F. Fecteau, Laura G. Corral, Emanuela M. Ghia, Svetlana Gaidarova, Diahnn Futalan, Ila Sri Bharati, Brian Cathers, Maria Schwaederlé, Bing Cui, Antonia Lopez-Girona, Davorka Messmer, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (10): 1637–1644.
https://doi.org/10.1182/blood-2014-03-559591
Published: 2014
Includes: Supplemental data
Journal Articles

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Bing Cui, Liguang Chen, Suping Zhang, Marek Mraz, Jessie-F. Fecteau, Jian Yu, Emanuela M. Ghia, Ling Zhang, Lei Bao, Laura Z. Rassenti, Karen Messer, George A. Calin, Carlo M. Croce, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (4): 546–554.
https://doi.org/10.1182/blood-2014-03-559690
Published: 2014
Includes: Supplemental data
Journal Articles

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Bing Cui, Ph.D, George F. Widhopf, II, PhD, Charles E. Prussak, Ph.D., Christina C.N. Wu, PhD, Anil Sadarangani, PhD, Suping Zhang, PhD, Fitzgerald Lao, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1637.
https://doi.org/10.1182/blood.V122.21.1637.1637
Published: 2013
Journal Articles

Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Christina C.N. Wu, PhD, Jian Yu, PhD, Fitzgerald Lao, Rommel Tawatao, Rongrong Wu, Esther Avery, B.S., Anil Sadarangani, PhD, Charles Prussak, PhD, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2873.
https://doi.org/10.1182/blood.V122.21.2873.2873
Published: 2013
Journal Articles

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Jian Yu, PhD, Bing Cui, Ph.D., George F. Widhopf, II, PhD, Liguang Chen, MD, PhD, Laura Rassenti, PhD, Zhengran Wang, BS, Shuyu Ma, BS, Tomoko Hayashi, M.D., Ph.D., Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4174.
https://doi.org/10.1182/blood.V122.21.4174.4174
Published: 2013
Journal Articles

ROR1 Can Interact With TCL1 and Enhance Leukemogenesis In Eµ-TCL1 Transgenic Mice

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Karen Messer, PhD, Zhouxin Shen, Steven P. Briggs, Ph.D, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 868.
https://doi.org/10.1182/blood.V122.21.868.868
Published: 2013
Journal Articles

Impact of oxygen concentration on growth of mesenchymal stromal cells from the marrow of patients with chronic lymphocytic leukemia

Brief Report
Jessie-F. Fecteau, Davorka Messmer, Suping Zhang, Bing Cui, Liguang Chen, Thomas J. Kipps
Journal: Blood
Blood (2013) 121 (6): 971–974.
https://doi.org/10.1182/blood-2012-08-447813
Published: 2013
Includes: Supplemental data
Journal Articles

Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Eva Hellqvist, Ph.D, Christina C.N. Wu, Ph.D., George F. Widhopf, II, PhD, Alice Shih, Rommel Tawatao, Fitzgerald Lao, Bing Cui, Ph.D., Charles Prussak, PhD, Anil Sadarangani, Ph.D., Dennis A. Carson, M.D., Catriona Jamieson, MD, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3886.
https://doi.org/10.1182/blood.V120.21.3886.3886
Published: 2012
Journal Articles

Mir-155 Contributed to Chronic Lymphocytic Leukemia Survival by Modulation of BCR-Signalling

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, B.S., Michelle Salcedo, BS, Carlo M. Croce, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 620.
https://doi.org/10.1182/blood.V118.21.620.620
Published: 2011
Journal Articles

A Monoclonal Antibody Specifically Targeting CD44 Inhibits B-Cell Chronic Lymphocytic Leukemia Cell Survival In Vitro and In Vivo

Suping Zhang, PhD, Christina C.N. Wu, Ph.D., Jessie-Farah Fecteau, Ph.D., Bing Cui, PhD, Rongrong Wu, Laura Z. Rassenti, Ph.D., Fitzgerald S. Lao, B.S., Rommel Tawatao, B.S., Stefan Weigland, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 927.
https://doi.org/10.1182/blood.V118.21.927.927
Published: 2011
Journal Articles

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

Bing CUi, PhD, George F. Widhopf, II, PhD, Jian Yu, PhD, Daniel Martinez, BS, Esther Avery, B.S., Suping Zhang, PhD, Liguang Chen, MD, PhD, Rongrong Wu, Christina C.N. Wu, Ph.D., Charles Prussak, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 984.
https://doi.org/10.1182/blood.V118.21.984.984
Published: 2011
Journal Articles

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Jessie-Farah Fecteau, Ph.D., Davorka Messmer, PhD, Suping Zhang, PhD, Bing Cui, PhD, Liguang Chen, MD, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 2839.
https://doi.org/10.1182/blood.V118.21.2839.2839
Published: 2011
Journal Articles

ROR1 Expression Accelerates Leukemia Development in RORxTCL1 Transgenic Mice,

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Esther Avery, B.S., George Chen, B.S., Masato Obara, MD, PhD, Karen Messer, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 3905.
https://doi.org/10.1182/blood.V118.21.3905.3905
Published: 2011
Journal Articles

Influence of Mir-155 On B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia.

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, Michelle Salcedo, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2343.
https://doi.org/10.1182/blood.V114.22.2343.2343
Published: 2009