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Journal Articles

Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21 WAF1/Cip1 -dependent mechanism independent of functional p53

Jessie-F. Fecteau, Laura G. Corral, Emanuela M. Ghia, Svetlana Gaidarova, Diahnn Futalan, Ila Sri Bharati, Brian Cathers, Maria Schwaederlé, Bing Cui, Antonia Lopez-Girona, Davorka Messmer, Thomas J. Kipps

Blood (2014) 124 (10): 1637–1644.

https://doi.org/10.1182/blood-2014-03-559591

Published: 2014

Includes: Supplemental data

Journal Articles

Lenalidomide Inhibits Proliferation Of Chronic Lymphocytic Leukemia Cells Via a Cereblon/p21 WAF1/Cip1 -Dependent Mechanism

Jessie-Farah Fecteau, Ph.D., Laura G Corral, Diahnn Futalan, Svetlana Gaidarova, MS, Ila Bharati, BS, Brian Cathers, PhD, Emanuela M. Ghia, PhD, Maria Schwaederlé, PharmaD, Antonia Lopez-Girona, Ph.D., Davorka Messmer, PhD, Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 4139.

https://doi.org/10.1182/blood.V122.21.4139.4139

Published: 2013

Journal Articles

Treatment of Chronic Lymphocytic Leukemia Patients with Lenalidomide Induces Down-Regulation of miR342-3p Associated with Over-Expression of Tumor Suppressor RASSF4,

Emanuela M. Ghia, PhD, Lillian Werner, Danelle F. James, M.D., Donna Neuberg, ScD, Laura G Corral, Senior, Scientist, Laura Z. Rassenti, Ph.D., Carlo M. Croce, MD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 3885.

https://doi.org/10.1182/blood.V118.21.3885.3885

Published: 2011

Journal Articles

Lenalidomide Inhibits Proliferation of Chronic Lymphocytic Leukemia Cells in Vitro

Jessie-Farah Fecteau, Ph.D., Diahnn Futalan, Ila Bharati, BS, Emanuela M. Ghia, PhD, Laura G Corral, Senior, Thomas J. Kipps, M.D., Ph.D, Davorka Messmer, PhD

Blood (2011) 118 (21): 1775.

https://doi.org/10.1182/blood.V118.21.1775.1775

Published: 2011

Journal Articles

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Steffen E. Meiler, Marlene Wade, Ferdane Kutlar, Shobha D. Yerigenahally, Yongjun Xue, Laure A. Moutouh-de Parseval, Laura G. Corral, Paul S. Swerdlow, Abdullah Kutlar

Blood (2011) 118 (4): 1109–1112.

https://doi.org/10.1182/blood-2010-11-319137

Published: 2011

Includes: Supplemental data

Journal Articles

Treatment of MCL Cells with Combined Rituximab and Lenalidomide Enhances NK-Mediated Synapse Formation and Cell Killing.

Svetlana Gaidarova, Laura G Corral, Emilia Glezer, Peter H Schafer, Antonia Lopez-Girona

Blood (2009) 114 (22): 1687.

https://doi.org/10.1182/blood.V114.22.1687.1687

Published: 2009

Journal Articles

Pomalidomide Modifies Sickle Cell Related Organ Damage in Transgenic Mice with Sickle Cell Anemia.

Steffen E. Meiler, MD, Marlene Wade, Laure Moutouh de Parseval, MD, Laura G Corral, Paul S. Swerdlow, MD, Ferdane Kutlar, MD, Abdullah Kutlar

Blood (2009) 114 (22): 904.

https://doi.org/10.1182/blood.V114.22.904.904

Published: 2009

Journal Articles

Lenalidomide Alone and in Combination with Rituximab Enhances NK Cell Immune Synapse Formation in Chronic Lymphocytic Leukemia (CLL) Cells in Vitro through Activation of Rho and Rac1 GTPases.

Svetlana Gaidarova, JianWu Li, M.D., Laura G Corral, Emilia Glezer, Peter H Schafer, Weilin Xie, Antonia Lopez-Girona, Bruce D. Cheson, MD, Brydon Bennett

Blood (2009) 114 (22): 3441.

https://doi.org/10.1182/blood.V114.22.3441.3441

Published: 2009

Journal Articles

Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases

Yibing Xu, Jianwu Li, Gregory D. Ferguson, Frank Mercurio, Gody Khambatta, Lisa Morrison, Antonia Lopez-Girona, Laura G. Corral, David R. Webb, Brydon L. Bennett, Weilin Xie

Blood (2009) 114 (2): 338–345.

https://doi.org/10.1182/blood-2009-02-200543

Published: 2009

Journal Articles

Treatment with Lenalidomide (Revlimid ® ) Upregulates CD40 Expression on CLL Cells and Increases Their Sensitivity to CD40-Mediated Cytotoxicity in Vitro

Emilia Glezer, Alessandra Ferrajoli, James M. Reuben, Laura G Corral

Blood (2008) 112 (11): 3168.

https://doi.org/10.1182/blood.V112.11.3168.3168

Published: 2008

Journal Articles

Identification of Novel Activities of Immunomodulatory Drugs: Cytoskeleton Reorganization through Modulation of Rho GTPases

Yibing Xu, PhD, JianWu Li, M.D., Greg Ferguson, Ph.D., Frank Mercurio, Ph.D., Gody Khambatta, Lisa Morrison, Ph.D., Antonia Lopez-Girona, Laura G Corral, Sr., David Webb, Ph.D., Brydon L. Bennett, Ph.D., Weilin Xie, Ph.D.

Blood (2008) 112 (11): 2565.

https://doi.org/10.1182/blood.V112.11.2565.2565

Published: 2008

Journal Articles

Lenalidomide Enhances Anti-Tumor Effect of γδ T Cells against Mantle Cell Lymphoma

Svetlana Gaidarova, Laura G Corral, Emilia Gleizer, David Young, Helen Brady, Brydon Bennett, Antonia Lopez-Girona

Blood (2008) 112 (11): 2616.

https://doi.org/10.1182/blood.V112.11.2616.2616

Published: 2008

Journal Articles

Pomalidomide Augments Erythropoiesis and Fetal Hemoglobin Production in a Humanized Mouse Model of Sickle Cell Disease

Steffen E. Meiler, Marlene Wade, Zhong Chen, Preetha Ramalingam, Laure A Moutouhde Parseval, Laura G Corral, Ferdane Kutlar, Abdullah Kutlar

Blood (2008) 112 (11): 536.

https://doi.org/10.1182/blood.V112.11.536.536

Published: 2008

Journal Articles

Targeting the p27 E3 ligase SCF Skp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

Qing Chen, Weilin Xie, Deborah J. Kuhn, Peter M. Voorhees, Antonia Lopez-Girona, Derek Mendy, Laura G. Corral, Veronique Plantevin Krenitsky, Weiming Xu, Laure Moutouh-de Parseval, David R. Webb, Frank Mercurio, Keiichi I. Nakayama, Keiko Nakayama, Robert Z. Orlowski

Blood (2008) 111 (9): 4690–4699.

https://doi.org/10.1182/blood-2007-09-112904

Published: 2008

Includes: Supplemental data

Journal Articles

Lenalidomide and CC-4047 Inhibit the Proliferation of Namalwa Cancer Cells While Expanding CD34 + Progenitor Cells. New Insights on the Combination Therapy with Certain HDAC Inhibitors for Hematological Cancers.

Dominique Verhelle, PhD, Laura G. Corral, MS, Kevin Wong, BS, Jessica H. Mueller, MS, Laure Moutouh de Parseval, MD, Kristen Jensen-Pergakes, MS, Emilia Glezer, MS, Gregory D. Ferguson, PhD, Helen A. Brady, PhD

Blood (2006) 108 (11): 1120.

https://doi.org/10.1182/blood.V108.11.1120.1120

Published: 2006

Journal Articles

Targeting the p27 Kip1 E3 Ubiquitin Ligase for the Treatment of Multiple Myeloma and Other Hematological Malignancies.

Qing Chen, PhD, Weilin Xie, PhD, Deborah J. Kuhn, PhD, Peter M. Voorhees, MD, Derek Mendy, MD, Antonia Lopez-Girona, PhD, Veronique Plantevin, PhD, Weiming Xu, PhD, Laura De Parseval, PhD, Laura G. Corral, PhD, Emilia Glezer, PhD, Kyle Chan, PhD, Frank Mercurio, PhD, Robert Z. Orlowski, MD, PhD

Blood (2006) 108 (11): 372.

https://doi.org/10.1182/blood.V108.11.372.372

Published: 2006

Journal Articles

New Approaches to the Regulation of Erythropoiesis and Hematoglobin Synthesis in β-Hemoglobinopathies: Studies with the Immunomodulatory Drug CC-4047.

Laure A. Moutouh de Parseval, MD, Dominique Verhelle, Ph.D., Emilia Glezer, B.S., Helen Brady, Ph.D., Laura G. Corral, M.S., Christopher L. Morris, M.D., Ph.D., George Muller, Ph.D., Kyle Chan, Ph.D.

Blood (2006) 108 (11): 689.

https://doi.org/10.1182/blood.V108.11.689.689

Published: 2006

Journal Articles

The IMiDs® Immunomodulatory Drugs Revlimid® (Lenalidomide) and CC-4047 Induce Growth Arrest and Apoptosis in NHL Tumor Cells In Vitro.

Laura G. Corral, MS, Dan Zhu, Ph.D., Yuedi Wang, M.S., Bernd Stein, Ph.D.

Blood (2006) 108 (11): 2388.

https://doi.org/10.1182/blood.V108.11.2388.2388

Published: 2006

Journal Articles

Lenalidomide and Novel Immunomodulatory Drugs (IMiDs®): A New Approach to the Regulation of Erythropoiesis and Hemoglobin Synthesis in Anemia.

Laure Moutouh de Parseval, MD, Helen Brady, Ph.D, Dominique Verhelle, PhD, Laura G. Corral, MS, Emilia Glezer, BS, Christopher L. Morris, MD, PhD, Roger Chen, PhD, Kyle Chan, PhD

Blood (2005) 106 (11): 2702.

https://doi.org/10.1182/blood.V106.11.2702.2702

Published: 2005

NARROW

Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21 WAF1/Cip1 -dependent mechanism independent of functional p53

Lenalidomide Inhibits Proliferation Of Chronic Lymphocytic Leukemia Cells Via a Cereblon/p21 WAF1/Cip1 -Dependent Mechanism

Treatment of Chronic Lymphocytic Leukemia Patients with Lenalidomide Induces Down-Regulation of miR342-3p Associated with Over-Expression of Tumor Suppressor RASSF4,

Lenalidomide Inhibits Proliferation of Chronic Lymphocytic Leukemia Cells in Vitro

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

Treatment of MCL Cells with Combined Rituximab and Lenalidomide Enhances NK-Mediated Synapse Formation and Cell Killing.

Pomalidomide Modifies Sickle Cell Related Organ Damage in Transgenic Mice with Sickle Cell Anemia.

Lenalidomide Alone and in Combination with Rituximab Enhances NK Cell Immune Synapse Formation in Chronic Lymphocytic Leukemia (CLL) Cells in Vitro through Activation of Rho and Rac1 GTPases.

Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases

Treatment with Lenalidomide (Revlimid ® ) Upregulates CD40 Expression on CLL Cells and Increases Their Sensitivity to CD40-Mediated Cytotoxicity in Vitro

Identification of Novel Activities of Immunomodulatory Drugs: Cytoskeleton Reorganization through Modulation of Rho GTPases

Lenalidomide Enhances Anti-Tumor Effect of γδ T Cells against Mantle Cell Lymphoma

Pomalidomide Augments Erythropoiesis and Fetal Hemoglobin Production in a Humanized Mouse Model of Sickle Cell Disease

Targeting the p27 E3 ligase SCF Skp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

Lenalidomide and CC-4047 Inhibit the Proliferation of Namalwa Cancer Cells While Expanding CD34 + Progenitor Cells. New Insights on the Combination Therapy with Certain HDAC Inhibitors for Hematological Cancers.

Targeting the p27 Kip1 E3 Ubiquitin Ligase for the Treatment of Multiple Myeloma and Other Hematological Malignancies.

New Approaches to the Regulation of Erythropoiesis and Hematoglobin Synthesis in β-Hemoglobinopathies: Studies with the Immunomodulatory Drug CC-4047.

The IMiDs® Immunomodulatory Drugs Revlimid® (Lenalidomide) and CC-4047 Induce Growth Arrest and Apoptosis in NHL Tumor Cells In Vitro.

Lenalidomide and Novel Immunomodulatory Drugs (IMiDs®): A New Approach to the Regulation of Erythropoiesis and Hemoglobin Synthesis in Anemia.

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American Society of Hematology

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American Society of Hematology

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