1-20 of 22
Karen Messer
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Rituximab and High-Dose Methylprednisolone Debulking Prior to Venetoclax for Patients with Relapsed or Refractory CLL

Michael Y. Choi, Benjamin Heyman, Minya Pu, Emily Pittman, Karen Messer, Thomas J. Kipps
Journal: Blood
Blood (2022) 140 (Supplement 1): 12410–12411.
https://doi.org/10.1182/blood-2022-170897
Published: 2022
Journal Articles

Cirmtuzumab Consolidation for Treatment of Patients with Detectable CLL on Venetoclax

Benjamin Heyman, MD, Michael Y. Choi, MD, Emanuela M. Ghia, PhD, George F. Widhopf II, PhD, Minya Pu, PhD, Emily Pittman, PhD, Karen Messer, PhD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-134711
Published: 2020
Journal Articles

Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia

Yun Chen, Liguang Chen, Jian Yu, Emanuela M. Ghia, Michael Y. Choi, Ling Zhang, Suping Zhang, Elsa Sanchez-Lopez, George F. Widhopf, II, Karen Messer, Laura Z. Rassenti, Catriona Jamieson, Thomas J. Kipps
Journal: Blood
Blood (2019) 134 (13): 1084–1094.
https://doi.org/10.1182/blood.2019001366
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia

Christina Wu, PhD, Emanuela M. Ghia, PhD, Fitzgerald Lao, Minya Pu, PhD, Karen Messer, PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Dennis A. Carson, MD, Michael Y. Choi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3143.
https://doi.org/10.1182/blood-2018-99-119292
Published: 2018
Journal Articles

Cirmtuzumab Blocks Production of Proinflammatory Factors By Inhibiting Wnt5a/ROR1 Induced Activation of NF-Kappa B in Chronic Lymphocytic Leukemia

Yun Chen, PhD, Michael Y. Choi, MD, Liguang Chen, PhD, Jian Yu, PhD, Ling Zhang, Emanuela M. Ghia, PhD, Elsa Sanchez-Lopez, PhD, George F. Widhopf II, PhD, Karen Messer, PhD, Laura Z. Rassenti, PhD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4415.
https://doi.org/10.1182/blood-2018-99-111996
Published: 2018
Journal Articles

Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Ekaterina Vinogradova, PhD, Fitzgerald Lao, Emily Nan, Katie Ta, Karen Messer, PhD, Michael Choi, MD, Benjamin F. Cravatt, PhD, Dennis A. Carson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3838.
https://doi.org/10.1182/blood.V130.Suppl_1.3838.3838
Published: 2017
Journal Articles

Durable and Specific Inhibition of ROR1 Signaling Associates with Prolonged Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Treated with Cirmtuzumab

Michael Choi, MD, George F. Widhopf II, PhD, Jian Yu, PhD, Liguang Chen, PhD, Md. Kamrul Hasan, PhD, Laura Z. Rassenti, PhD, Emily Pittman, PhD, Karen Messer, PhD, Charlene Gutierrez, BS, Reilly Lilianna Kidwell, BSc, Charles E. Prussak, PharmD, PhD, Januario E Castro, MD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 829.
https://doi.org/10.1182/blood.V130.Suppl_1.829.829
Published: 2017
Journal Articles

Inhibition of Casein Kinase 2 Impairs Wnt Signaling and Cell Survival in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Fitzgerald S Lao, BS, Emily Nan, Hongying Li, PhD, Michael Y. Choi, MD, Karen Messer, PhD, Dennis A. Carson, MD
Journal: Blood
Blood (2016) 128 (22): 2050.
https://doi.org/10.1182/blood.V128.22.2050.2050
Published: 2016
Journal Articles

Immunotherapeutic Targeting of ROR1-Dependent, Non-Canonical Wnt5a-Signaling By Cirmtuzumab: A First-in-Human Phase I Trial for Patients with Intractable Chronic Lymphocytic Leukemia

Michael Y. Choi, MD, George F. Widhopf, II, PhD, Jian Yu, PhD, Reilly L Kidwell, BS, BA, CCRC, Laura Z. Rassenti, PhD, Charlene Gutierrez, Susette Gorak, Tiffany Juarez, PhD, Emily Pittman, PhD, Hongying Li, PhD, Karen Messer, PhD, Charles Prussak, PhD, Januario E. Castro, MD, Catriona Jamieson, MD PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3224.
https://doi.org/10.1182/blood.V128.22.3224.3224
Published: 2016
Journal Articles

Cirmtuzumab (UC-961), a First-in-Class Anti-ROR1 Monoclonal Antibody: Planned Interim Analysis of Initial Phase 1 Cohorts

Michael Y. Choi, MD, George F. Widhopf, II, PhD, Januario Castro, MD, Hongying Li, PhD, Reilly L Kidwell, BS, BA, CCRC, Sam C Zhang, B.A., Tiffany Juarez, PhD, Susette Gorak, Laura Z. Rassenti, PhD, Karen Messer, PhD, Charles Prussak, PhD, Catriona HM Jamieson, MD PhD, Thomas J. Kipps, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1736.
https://doi.org/10.1182/blood.V126.23.1736.1736
Published: 2015
Journal Articles

Inhibition of Wnt Signaling By Dimethyl Fumarate Results in in Vitro and in Vivo Clearance of Chronic Lymphocytic Leukemia Cells and Has Additive Activity with Ibrutinib

Christina C.N. Wu, PhD, Fitzgerald Lao, Hongying Li, PhD, Laura Rassenti, PhD, Thomas J. Kipps, MD, Karen Messer, PhD, Dennis A. Carson, MD, Michael Y. Choi, MD
Journal: Blood
Blood (2014) 124 (21): 4683.
https://doi.org/10.1182/blood.V124.21.4683.4683
Published: 2014
Journal Articles

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

Bing Cui, Liguang Chen, Suping Zhang, Marek Mraz, Jessie-F. Fecteau, Jian Yu, Emanuela M. Ghia, Ling Zhang, Lei Bao, Laura Z. Rassenti, Karen Messer, George A. Calin, Carlo M. Croce, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (4): 546–554.
https://doi.org/10.1182/blood-2014-03-559690
Published: 2014
Includes: Supplemental data
Journal Articles

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1

Marek Mraz, Liguang Chen, Laura Z. Rassenti, Emanuela M. Ghia, Hongying Li, Kristen Jepsen, Erin N. Smith, Karen Messer, Kelly A. Frazer, Thomas J. Kipps
Journal: Blood
Blood (2014) 124 (1): 84–95.
https://doi.org/10.1182/blood-2013-09-527234
Published: 2014
Includes: Supplemental data
Journal Articles

Lenalidomide and Rituximab For The Treatment Of Patients With Relapsed Or Refractory Chronic Lymphocytic Leukemia: Results Of Planned Interim Analysis

Michael Y. Choi, MD, Januario E. Castro, M.D., Sheila Hoff, RN, Hongying Li, PhD, Laura Rassenti, PhD, Danelle F. James, M.D., M.A.S., Karen Messer, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5299.
https://doi.org/10.1182/blood.V122.21.5299.5299
Published: 2013
Journal Articles

ROR1 Can Interact With TCL1 and Enhance Leukemogenesis In Eµ-TCL1 Transgenic Mice

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Karen Messer, PhD, Zhouxin Shen, Steven P. Briggs, Ph.D, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 868.
https://doi.org/10.1182/blood.V122.21.868.868
Published: 2013
Journal Articles

Impact of Deletion 17p On the Outcome of Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma.

Caitlin L. Costello, M.D., Edward D. Ball, M.D., Sue Corringham, R.N., Hongying Li, PhD, Karen Messer, PhD
Journal: Blood
Blood (2012) 120 (21): 3099.
https://doi.org/10.1182/blood.V120.21.3099.3099
Published: 2012
Journal Articles

The Target Genes and Prognostic Significance of Mir-150 in Chronic Lymphocytic Leukemia

Marek Mraz, MD, PhD, Laura Z. Rassenti, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Jessie-Farah Fecteau, Ph.D., Sarka Pospisilova, Dr, PhD, Hongying Li, PhD, Karen Messer, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3859.
https://doi.org/10.1182/blood.V120.21.3859.3859
Published: 2012
Journal Articles

ROR1 Expression Accelerates Leukemia Development in RORxTCL1 Transgenic Mice,

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Esther Avery, B.S., George Chen, B.S., Masato Obara, MD, PhD, Karen Messer, PhD, Thomas J. Kipps, M.D., Ph.D
Journal: Blood
Blood (2011) 118 (21): 3905.
https://doi.org/10.1182/blood.V118.21.3905.3905
Published: 2011
Journal Articles

Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist,

Alice Y Shih, BS, Annelie Schairer, Ph.D., Christian L Barrett, Ph.D., Ifat Geron, MSc, Angela C Court Recart, BS, MS, Daniel Goff, BS, Sacha Prashad, Jerry Wu, PharmD, Qingfei Jiang, PhD, Jason Gotlib, MD, MS, Larisa Balaian, Ph.D., Mark D. Minden, MD, PhD, Heather Leu, BS, Russell Wall, BS, Wenxue Ma, M.D., Ph.D., Kamran Shazand, PhD, John D McPherson, PhD, Steven M. Kornblau, MD, Ida Deichaite, PhD, Minya Pu, PhD, Lei Bao, PhD, Giovanni Martinelli, MD, Tannishtha Reya, PhD, Sheldon R Morris, MD, MPH, Todd VanArsdale, PhD, Thomas J Hudson, MD, Karen Messer, PhD, Hanna Mikkola, MD, PhD, Wendy J. Levin, MD, MS, Kelly A Frazer, Ph.D., Anil Sadarangani, Ph.D., Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3776.
https://doi.org/10.1182/blood.V118.21.3776.3776
Published: 2011
Journal Articles

Update of a Phase I/II Trial of 5-Azacytidine Prior to Gemtuzumab Ozogamicin (GO) for Patients with Relapsed Acute Myeloid Leukemia with Correlative Biomarker Studies

Edward D. Ball, MD, Bruno C. Medeiros, MD, Larissa Balaian, PhD, Tracy Roque, Sue Corringham, Richa Rajwanshi, Steven Coutre, Jason R Gotlib, MD, MS, Asad Bashey, MD, PhD, Karen Messer
Journal: Blood
Blood (2010) 116 (21): 3286.
https://doi.org/10.1182/blood.V116.21.3286.3286
Published: 2010