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Journal Articles

Poor prognosis is ZAP70’ed into focus in CLL

Adam J. Linley, Joseph R. Slupsky

Blood (2021) 137 (26): 3586–3587.

https://doi.org/10.1182/blood.2021011270

Published: 2021

Journal Articles

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

Jingyu Chen, Vijitha Sathiaseelan, Andrew Moore, Shengjiang Tan, Chandra Sekkar Reddy Chilamakuri, Valar Nila Roamio Franklin, Arash Shahsavari, Constanze A. Jakwerth, Sandra B. Hake, Alan J. Warren, Irina Mohorianu, Clive D’Santos, Ingo Ringshausen

Blood (2021) 137 (26): 3629–3640.

https://doi.org/10.1182/blood.2020009960

Published: 2021

Includes: Supplemental data

Journal Articles

Co-Expression of SYK and ZAP70 Subverts Negative B-Cell Selection and Enables Oncogenic Signaling in Multiple B-Cell Malignancies

Teresa Sadras, PhD, Mickaël Martin, MD PhD, Lauren Kim-Sing, Jevon Cutler, PhD, Gal Lenz, PhD, Anne Marie Knapp, Dana Ghergus, MD PhD, Fabien Delmotte, Cédric Schleiss, Anne-Sophie Korganow, MD PhD, Pauline Soulas-Sprauel, PharmD, PhD, Zhengshan Chen, MD PhD, Akhilesh Pandey, MD PhD, David M. Weinstock, MD, Hassan Jumaa, PhD, Eric Meffre, PhD, Thierry Martin, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 295.

https://doi.org/10.1182/blood-2019-128999

Published: 2019

Journal Articles

Molecular Genetics and Prognosis in Younger Patients with Chronic Lymphocytic Leukemia (CLL)

Daniel Helbig, MD, Ghaith Abu Zeinah, MD, Erica B Bhavsar, BS, Richard R. Furman, MD, John N. Allan, MD

Blood (2019) 134 (Supplement_1): 3025.

https://doi.org/10.1182/blood-2019-125426

Published: 2019

Journal Articles

A Core Proliferative Program Induced By B-Cell Receptor Stimulation in Chronic Lymphocytic Leukemia Cells

Cédric Schleiss, Raphael Carapito, PhD, Luc Mathieu Fornecker, MD PhD, Leslie Muller, Paul Nicodeme, Ouria Tahar, Angélique Pichot, BSc, Laurent Mauvieux, MD PhD, Raoul Herbrecht, MD, Myriam Maumy-Bertrand, Jean-Noel Freund, Christine Carapito, Seiamak Bahram, MD, Frederic Bertrand, Laurent Vallat, MD PhD

Blood (2019) 134 (Supplement_1): 3777.

https://doi.org/10.1182/blood-2019-126779

Published: 2019

Journal Articles

UM171 Regulates the Hematopoietic Differentiation of Human Acquired Aplastic Anemia-Derived Induced Pluripotent Stem Cells

Tellechea Maria Florencia, MSc, Flavia S. Donaires, PhD, Tiago C. Silva, PhD, Lilian F. Moreira, PhD, Yordanka Armenteros, PhD, Rodrigo T. Calado, MD PhD

Blood (2019) 134 (Supplement_1): 2500.

https://doi.org/10.1182/blood-2019-127466

Published: 2019

Journal Articles

N6-Methyladenosine RNA Methylation Regulators Contribute to Malignant Progression and Survival Prediction in Chronic Lymphocytic Leukemia

Ya Zhang, MD, Xiaosheng Fang, PhD, Na Chen, MD, Xiao Lv, PhD, Xueling Ge, PhD, Kang Lu, MD PhD, Xiangxiang Zhou, MD, Juan Yang, MM, Yang Han, MM, Shunfeng Hu, Xin Wang, MD PhD

Blood (2019) 134 (Supplement_1): 1738.

https://doi.org/10.1182/blood-2019-126469

Published: 2019

Journal Articles

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Patrick Harrington, MRCP, FRCPath, Richard Dillon, MA, PhD MRCP, FRCPath, Philippe Rousselot, MD PhD, Deepti Radia, Yvonne Francis, Claire N Harrison, Professor, Shahram Kordasti, MD PhD, Hugues De Lavallade

Blood (2019) 134 (Supplement_1): 1635.

https://doi.org/10.1182/blood-2019-129135

Published: 2019

Journal Articles

Identification of Small Molecule Kinase Inhibitors That Potently and Reversibly Block Chimeric Antigen Receptor T Cell Proliferation and Cytotoxicity

Parmeshwar Amatya, PhD, Matthew L. Cooper, PhD, Alun J Carter, PhD BSc, John F. DiPersio, MD PhD

Blood (2019) 134 (Supplement_1): 2068.

https://doi.org/10.1182/blood-2019-126165

Published: 2019

Journal Articles

Modelling Single Cell B-Cell Receptor Signaling Reveals Enhanced Activity in Primary CLL Cells Compared to Non-Malignant Cells While Fundamental Network Circuit Topology Remains Stable Even with Novel Therapeutic Inhibitors

Daniel Mertens, PhD, Christine Wolf, PhD, Carsten Maus, PhD, Michael Persicke, Katharina Filarsky, PhD, Hartmut Döhner, Peter Lichter, PhD, Thomas Höfer, PhD, Stephan Stilgenbauer, MD

Blood (2019) 134 (Supplement_1): 4275.

https://doi.org/10.1182/blood-2019-127837

Published: 2019

Journal Articles

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Specific Kinase Activation Signatures That Can Predict Response to Targeted Therapy

Valentina Cordo', MSc, Rico Hagelaar, Sander Piersma, Thang V Pham, Connie Jimenez, PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 4649.

https://doi.org/10.1182/blood-2019-122898

Published: 2019

Journal Articles

Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

Blood (2019) 134 (8): 688–698.

https://doi.org/10.1182/blood.2019000490

Published: 2019

Includes: Supplemental data

Journal Articles

The Amount of Apoptosis Predicts Outcome in Ibrutinib-Treated Chronic Lymphocytic Leukemia (CLL)

Giovanni Del Poeta, MD, Massimiliano Postorino, MD, Federico Pozzo, PhD, Maria Ilaria Del Principe, MD, Enrico Santinelli, MD, Riccardo Bomben, PhD, Annalisa Biagi, MD, Francesco Buccisano, MD, Francesca Maria Rossi, PhD, Adriano Venditti, MD, Paolo de Fabritiis, MD, Maria Cantonetti, MD, Sergio Amadori, MD, Valter Gattei, MD, William Arcese

Blood (2018) 132 (Supplement 1): 4397.

https://doi.org/10.1182/blood-2018-99-113060

Published: 2018

Journal Articles

Ibrutinib Alone or in Combination with Rituximab Produces Superior Progression Free Survival (PFS) Compared with Bendamustine Plus Rituximab in Untreated Older Patients with Chronic Lymphocytic Leukemia (CLL): Results of Alliance North American Intergroup Study A041202

Blood (2018) 132 (Supplement 1): 6.

https://doi.org/10.1182/blood-2018-99-116653

Published: 2018

Journal Articles

Cooperation between SYK and ZAP70 Kinases As a Driver of Oncogenic BCR-Signaling in B-Cell Malignancies

Teresa Sadras, PhD, Jevon Cutler, Julia Aguade-Gorgorio, PhD, Zhengshan Chen, MD PhD, Kadriye Nehir Cosgun, PhD, Akhilesh Pandey, MD PhD, Markus Muschen, MD

Blood (2018) 132 (Supplement 1): 3922.

https://doi.org/10.1182/blood-2018-99-116954

Published: 2018

Journal Articles

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Stephanie Kim, BS, Rami Khoriaty, MD, Rajesh Valanparambil, PhD, Julia Wu, PhD, Austin Taylor, BS, Hideaki Fujiwara, MD, Dan Peltier, MD, Yaping Sun, MD PhD MS, Israel Henig, MD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Stuart Brabbs, Rafi Ahmed, PhD, David Ginsburg, MD, Pavan Reddy, MD

Blood (2018) 132 (Supplement 1): 859.

https://doi.org/10.1182/blood-2018-99-111628

Published: 2018

Journal Articles

98% IGHV Gene Identity Is Still the Optimal Cutoff to Predict the Prognosis of Chronic Lymphocytic Leukemia Patients in China

Yi Xia, Ke Shi, Qian Sun, Chun Qiao, Huayuan Zhu, Li Wang, MD, Lei Fan, MD PhD, Wei Xu, Jianyong Li, MD PhD

Blood (2018) 132 (Supplement 1): 5545.

https://doi.org/10.1182/blood-2018-99-118141

Published: 2018

Journal Articles

TP53 Aberrations By FISH in CLL and Complex Karyotype at Transformation Predict for Worse Outcome in Diffuse Large B-Cell Lymphoma - Richter Transformation: A Single Institution Series of 75 DLBCL-RT Cases

Shiraz Fidai, MD, Madina Sukhanova, PhD, Brian C.-H. Chiu, PhD, Y. Lynn Lynn Wang, MD PhD, Wendy Stock, MD, Peter A Riedell, MD, Sonali M. Smith, MD, Elizabeth Hyjek, MD, Girish Venkataraman, MD MBBS

Blood (2018) 132 (Supplement 1): 2984.

https://doi.org/10.1182/blood-2018-99-112242

Published: 2018

Journal Articles

ZAP-70 Expression in Non Tumoral B Cells: Role in B Tolerance Breakdown?

Mickaël Martin, MD PhD, Anne Marie Knapp, Dana Ghergus, MD PhD, Fabien Delmotte, Laurent Vallat, MD PhD, Cédric Schleiss, Raoul Herbrecht, MD, Anne-Sophie Korganow, MD PhD, Frédéric Gros, PhD, Sophie Jung, DMD, PhD, Pauline Soulas-Sprauel, PharmD, PhD, Eric Meffre, PhD, Thierry Martin, MD PhD

Blood (2018) 132 (Supplement 1): 1114.

https://doi.org/10.1182/blood-2018-99-118237

Published: 2018

Journal Articles

Interferon Regulatory Factor 4 Orchestrates the Response to B-Cell Receptor in Chronic Lymphocytic Leukemia Cells By Regulating Ikaros

Rossana Maffei, Stefania Fiorcari, PhD, Silvia Martinelli, Stefania Benatti, Patrizia Zucchini, Giulia Debbia, Leonardo Potenza, Mario Luppi, Roberto Marasca

Blood (2017) 130 (Supplement 1): 59.

https://doi.org/10.1182/blood.V130.Suppl_1.59.59

Published: 2017

NARROW

Poor prognosis is ZAP70’ed into focus in CLL

ZAP-70 constitutively regulates gene expression and protein synthesis in chronic lymphocytic leukemia

Co-Expression of SYK and ZAP70 Subverts Negative B-Cell Selection and Enables Oncogenic Signaling in Multiple B-Cell Malignancies

Molecular Genetics and Prognosis in Younger Patients with Chronic Lymphocytic Leukemia (CLL)

A Core Proliferative Program Induced By B-Cell Receptor Stimulation in Chronic Lymphocytic Leukemia Cells

UM171 Regulates the Hematopoietic Differentiation of Human Acquired Aplastic Anemia-Derived Induced Pluripotent Stem Cells

N6-Methyladenosine RNA Methylation Regulators Contribute to Malignant Progression and Survival Prediction in Chronic Lymphocytic Leukemia

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Identification of Small Molecule Kinase Inhibitors That Potently and Reversibly Block Chimeric Antigen Receptor T Cell Proliferation and Cytotoxicity

Modelling Single Cell B-Cell Receptor Signaling Reveals Enhanced Activity in Primary CLL Cells Compared to Non-Malignant Cells While Fundamental Network Circuit Topology Remains Stable Even with Novel Therapeutic Inhibitors

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Specific Kinase Activation Signatures That Can Predict Response to Targeted Therapy

Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

The Amount of Apoptosis Predicts Outcome in Ibrutinib-Treated Chronic Lymphocytic Leukemia (CLL)

Ibrutinib Alone or in Combination with Rituximab Produces Superior Progression Free Survival (PFS) Compared with Bendamustine Plus Rituximab in Untreated Older Patients with Chronic Lymphocytic Leukemia (CLL): Results of Alliance North American Intergroup Study A041202

Cooperation between SYK and ZAP70 Kinases As a Driver of Oncogenic BCR-Signaling in B-Cell Malignancies

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

98% IGHV Gene Identity Is Still the Optimal Cutoff to Predict the Prognosis of Chronic Lymphocytic Leukemia Patients in China

TP53 Aberrations By FISH in CLL and Complex Karyotype at Transformation Predict for Worse Outcome in Diffuse Large B-Cell Lymphoma - Richter Transformation: A Single Institution Series of 75 DLBCL-RT Cases

ZAP-70 Expression in Non Tumoral B Cells: Role in B Tolerance Breakdown?

Interferon Regulatory Factor 4 Orchestrates the Response to B-Cell Receptor in Chronic Lymphocytic Leukemia Cells By Regulating Ikaros

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American Society of Hematology

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American Society of Hematology

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