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Issue Archive

Volume 2, Issue 19
October 9 2018
Blood Advances Cover Image for Volume 2, Issue 19

Table of Contents

CLINICAL TRIALS AND OBSERVATIONS

Graphical abstract for: Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study;
Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study
Clinical Trials & Observations
Ada Gillissen,on behalf of the TeMpOH-1 Study Group,Thomas van den Akker,on behalf of the TeMpOH-1 Study Group,Camila Caram-Deelder,on behalf of the TeMpOH-1 Study Group,Dacia D. C. A. Henriquez,on behalf of the TeMpOH-1 Study Group,Kitty W. M. Bloemenkamp,on behalf of the TeMpOH-1 Study Group,Moniek P. M. de Maat,on behalf of the TeMpOH-1 Study Group,Jos J. M. van Roosmalen,on behalf of the TeMpOH-1 Study Group,Joost J. Zwart,on behalf of the TeMpOH-1 Study Group,Jeroen Eikenboom,on behalf of the TeMpOH-1 Study Group,Johanna G. van der Bom,on behalf of the TeMpOH-1 Study Group
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Graphical abstract for: Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients;
Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients
Clinical Trials & Observations
Erica B. Esrick,John P. Manis,Heather Daley,Cristina Baricordi,Hélène Trébéden-Negre,Francis J. Pierciey,Myriam Armant,Sarah Nikiforow,Matthew M. Heeney,Wendy B. London,Luca Biasco,Mohammed Asmal,David A. Williams,Alessandra Biffi
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Graphical abstract for: Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation;

Professional illustration by Patrick Lane, ScEYEnce Studios.

Daratumumab in life-threatening autoimmune hemolytic anemia following hematopoietic stem cell transplantation
Clinical Trials & Observations
Catharina Schuetz,Manfred Hoenig,Despina Moshous,Christof Weinstock,Martin Castelle,Matthieu Bendavid,Kristin Shimano,Vanessa Tolbert,Ansgar S. Schulz,Christopher C. Dvorak
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HEMATOPOIESIS AND STEM CELLS

Graphical abstract for: ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1;
ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1
Nidhi Rohatgi,Wei Zou,Patrick L. Collins,Jonathan R. Brestoff,Timothy H. Chen,Yousef Abu-Amer,Steven L. Teitelbaum
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

Graphical abstract for: NK cell development in a human stem cell niche: KIR expression occurs independently of the presence of HLA class I ligands;
NK cell development in a human stem cell niche: KIR expression occurs independently of the presence of HLA class I ligands
Xiaoyi Zhao,Sandra Weinhold,Jens Brands,Maryam Hejazi,Özer Degistirici,Gesine Kögler,Roland Meisel,Markus Uhrberg
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Graphical abstract for: Accelerated, but not conventional, radiotherapy of murine B-cell lymphoma induces potent T cell–mediated remissions;
Accelerated, but not conventional, radiotherapy of murine B-cell lymphoma induces potent T cell–mediated remissions
Suparna Dutt,Michelle B. Atallah,Yoshitaka Minamida,Alexander Filatenkov,Kent P. Jensen,Bettina P. Iliopoulou,Rasa Tamosiuniene,Jeffrey Waters,Edgar G. Engleman,Samuel Strober
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LYMPHOID NEOPLASIA

Graphical abstract for: An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors;
An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors
Sondra Downey-Kopyscinski,Ellen W. Daily,Marc Gautier,Ananta Bhatt,Bogdan I. Florea,Constantine S. Mitsiades,Paul G. Richardson,Christoph Driessen,Herman S. Overkleeft,Alexei F. Kisselev
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Graphical abstract for: Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by <em>Mll-Af4</em> and activated <em>Ras</em>;
Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by Mll-Af4 and activated Ras
S. Haihua Chu,Evelyn J. Song,Jonathan R. Chabon,Janna Minehart,Chloe N. Matovina,Jessica L. Makofske,Elizabeth S. Frank,Kenneth Ross,Richard P. Koche,Zhaohui Feng,Haiming Xu,Andrei Krivtsov,Andre Nussenzweig,Scott A. Armstrong
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Graphical abstract for: Proteomic profiling identifies outcome-predictive markers in patients with peripheral T-cell lymphoma, not otherwise specified;
Proteomic profiling identifies outcome-predictive markers in patients with peripheral T-cell lymphoma, not otherwise specified
Clinical Trials & Observations
Maja Ludvigsen,Martin Bjerregård Pedersen,Kristina Lystlund Lauridsen,Tim Svenstrup Poulsen,Stephen Jacques Hamilton-Dutoit,Søren Besenbacher,Knud Bendix,Michael Boe Møller,Peter Nørgaard,Francesco d’Amore,Bent Honoré
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Graphical abstract for: Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL;
Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL
Clinical Trials & Observations
Ina-Katrin Siekmann,Kevin Dierck,Sebastian Prall,Marianne Klokow,Julia Strauss,Sophia Buhs,Antonina Wrzeszcz,Michael Bockmayr,Florian Beck,Magdalena Trochimiuk,Kristina Gottschling,Victoria Martens,Melissa Khosh-Naucke,Helwe Gerull,Jürgen Müller,Lena Behrmann,Martin Blohm,René P. Zahedi,Irmela Jeremias,Albert Sickmann,Peter Nollau,Martin A. Horstmann
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MYELOID NEOPLASIA

Graphical abstract for: Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia;
Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia
Coline Gaillard,Sangeetha Surianarayanan,Trevor Bentley,Matthew R. Warr,Briana Fitch,Huimin Geng,Emmanuelle Passegué,Hugues de Thé,Scott C. Kogan
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Graphical abstract for: KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice;
KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice
Yue Wei,Hong Zheng,Naran Bao,Shan Jiang,Carlos E. Bueso-Ramos,Joseph Khoury,Caleb Class,Yue Lu,Kevin Lin,Hui Yang,Irene Ganan-Gomez,Daniel T. Starczynowski,Kim-Anh Do,Simona Colla,Guillermo Garcia-Manero
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Graphical abstract for: Cell-lineage level–targeted sequencing to identify acute myeloid leukemia with myelodysplasia-related changes;
Cell-lineage level–targeted sequencing to identify acute myeloid leukemia with myelodysplasia-related changes
Kazuaki Yokoyama,Eigo Shimizu,Nozomi Yokoyama,Sousuke Nakamura,Rika Kasajima,Miho Ogawa,Tomomi Takei,Mika Ito,Asako Kobayashi,Rui Yamaguchi,Seiya Imoto,Satoru Miyano,Arinobu Tojo
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THROMBOSIS AND HEMOSTASIS

Graphical abstract for: Humanized GPIbα–von Willebrand factor interaction in the mouse;
Humanized GPIbα–von Willebrand factor interaction in the mouse
Sachiko Kanaji,Jennifer N. Orje,Taisuke Kanaji,Yuichi Kamikubo,Yosuke Morodomi,Yunfeng Chen,Alessandro Zarpellon,Jerome Eberhardt,Stefano Forli,Scot A. Fahs,Rashmi Sood,Sandra L. Haberichter,Robert R. Montgomery,Zaverio M. Ruggeri
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TRANSFUSION MEDICINE

Graphical abstract for: Eculizumab in cold agglutinin disease (DECADE): an open-label, prospective, bicentric, nonrandomized phase 2 trial;
Eculizumab in cold agglutinin disease (DECADE): an open-label, prospective, bicentric, nonrandomized phase 2 trial
Clinical Trials & Observations
Alexander Röth,Martin Bommer,Andreas Hüttmann,Dörte Herich-Terhürne,Nils Kuklik,Jan Rekowski,Veronika Lenz,Hubert Schrezenmeier,Ulrich Dührsen
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TRANSPLANTATION

Graphical abstract for: Chromosome Y–encoded antigens associate with acute graft-versus-host disease in sex-mismatched stem cell transplant;
Chromosome Y–encoded antigens associate with acute graft-versus-host disease in sex-mismatched stem cell transplant
Clinical Trials & Observations
Wei Wang,Hu Huang,Michael Halagan,Cynthia Vierra-Green,Michael Heuer,Jason E. Brelsford,Michael Haagenson,Richard H. Scheuermann,Amalio Telenti,William Biggs,Nathaniel M. Pearson,Julia Udell,Stephen Spellman,Martin Maiers,Caleb J. Kennedy
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COMMENTARY

The ASH Agenda for Hematology Research: a roadmap for advancing scientific discovery and cures for hematologic diseases
Charles G. Mullighan
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  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Mice were generated with conditional deletion of ASXL1 in myeloid cells. This image shows mouse femur histology with staining for tartrate-resistant acid phosphatase (red reaction product) activity to highlight the marked increase in osteoclasts in these mice. See the article by Rohatgi et al.

  • PDF Icon Front MatterFront Matter
  • PDF Icon Editorial BoardEditorial Board
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