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Issue Archive

Volume 2, Issue 5
March 13 2018
Blood Advances Cover Image for Volume 2, Issue 5

Table of Contents

STIMULUS REPORT

Graphical abstract for: Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model;
Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model
Robert A. French,Benjamin J. Samelson-Jones,Glenn P. Niemeyer,Clinton D. Lothrop, Jr,Elizabeth P. Merricks,Timothy C. Nichols,Valder R. Arruda
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REVIEW ARTICLE

Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease
Hitomi Hosoya,Jeffrey Levine,Peter Abt,David Henry,David L. Porter,Saar Gill
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CLINICAL TRIALS AND OBSERVATIONS

Graphical abstract for: CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine;
CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine
Clinical Trials & Observations
Raphaelle Fanciullino,Laure Farnault,Mélanie Donnette,Diane-Charlotte Imbs,Catherine Roche,Geoffroy Venton,Yael Berda-Haddad,Vadim Ivanov,Joseph Ciccolini,L’Houcine Ouafik,Bruno Lacarelle,Regis Costello
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Graphical abstract for: Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study;
Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study
Clinical Trials & Observations
Andreas K. Øvlisen,Anders Oest,Mette D. Bendtsen,John Bæch,Preben Johansen,Line S. Lynggaard,Ingolf Mølle,Thomas B. Mortensen,Duruta Weber,Gideon Ertner,Claudia Schöllkopf,Jesper Q. Thomassen,Ove Juul Nielsen,Lene Sofie Granfeldt Østgård,Martin Bøgsted,Karen Dybkær,Hans E. Johnsen,Marianne T. Severinsen
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HEMATOPOIESIS AND STEM CELLS

Graphical abstract for: <em>Sipa1</em> deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm;
Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm
Pingnan Xiao,Monika Dolinska,Lakshmi Sandhow,Makoto Kondo,Anne-Sofie Johansson,Thibault Bouderlique,Ying Zhao,Xidan Li,Marios Dimitriou,George Z. Rassidakis,Eva Hellström-Lindberg,Nagahiro Minato,Julian Walfridsson,David T. Scadden,Mikael Sigvardsson,Hong Qian
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

Graphical abstract for: A novel method to generate T-cell receptor–deficient chimeric antigen receptor T cells;
A novel method to generate T-cell receptor–deficient chimeric antigen receptor T cells
Takahiro Kamiya,Desmond Wong,Yi Tian Png,Dario Campana
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LYMPHOID NEOPLASIA

Graphical abstract for: Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia;
Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia
Clinical Trials & Observations
Thai Hoa Tran,Marian H. Harris,Jonathan V. Nguyen,Traci M. Blonquist,Kristen E. Stevenson,Eileen Stonerock,Barbara L. Asselin,Uma H. Athale,Luis A. Clavell,Peter D. Cole,Kara M. Kelly,Caroline Laverdiere,Jean-Marie Leclerc,Bruno Michon,Marshall A. Schorin,Jennifer J. G. Welch,Shalini C. Reshmi,Donna S. Neuberg,Stephen E. Sallan,Mignon L. Loh,Lewis B. Silverman
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MYELOID NEOPLASIA

Graphical abstract for: Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas;
Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas
Alexandra Nagy,Aparna Bhaduri,Nahid Shahmarvand,Jahanbanoo Shahryari,James L. Zehnder,Roger A. Warnke,Tariq Mughal,Siraj Ali,Robert S. Ohgami
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Graphical abstract for: IMiD compounds affect CD34<sup>+</sup> cell fate and maturation via CRBN-induced IKZF1 degradation;
IMiD compounds affect CD34+ cell fate and maturation via CRBN-induced IKZF1 degradation
Shirong Li,Jing Fu,Hui Wang,Huihui Ma,Xiaoming Xu,Yong-Guang Yang,Shixian Deng,Markus Y. Mapara,Suzanne Lentzsch
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Graphical abstract for: RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice;
RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice
Ken Morita,Chieko Tokushige,Shintaro Maeda,Hiroki Kiyose,Mina Noura,Atsushi Iwai,Maya Yamada,Gengo Kashiwazaki,Junichi Taniguchi,Toshikazu Bando,Masahiro Hirata,Tatsuki R. Kataoka,Tatsutoshi Nakahata,Souichi Adachi,Hiroshi Sugiyama,Yasuhiko Kamikubo
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PLATELETS AND THROMBOPOIESIS

Graphical abstract for: Platelet TGF-β1 deficiency decreases liver fibrosis in a mouse model of liver injury;
Platelet TGF-β1 deficiency decreases liver fibrosis in a mouse model of liver injury
Shahrouz Ghafoory,Rohan Varshney,Tyler Robison,Karim Kouzbari,Sean Woolington,Brennah Murphy,Lijun Xia,Jasimuddin Ahamed
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THROMBOSIS AND HEMOSTASIS

Graphical abstract for: Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors;
Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors
Alexey Dementiev,Abel Silva,Calvin Yee,Zhe Li,Michael T. Flavin,Hing Sham,James R. Partridge
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TRANSPLANTATION

Graphical abstract for: Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation;
Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation
Clinical Trials & Observations
Coco de Koning,Julie-Anne Gabelich,Jurgen Langenhorst,Rick Admiraal,Jurgen Kuball,Jaap Jan Boelens,Stefan Nierkens
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ERRATUM

Francica JR, Zak DE, Linde C, et al. Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs. Blood Adv. 2017;1(25):2329-2342.
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  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    CD34+ cells stably transduced with a lentivirus carrying the control short hairpin RNA were treated with pomalidomide (1 μM) for 6 hours. The cells were then stained for IKZF1 (red) or green fluorescent protein (green), using DAPI (4′,6-diamidino-2-phenylindole) for nuclear counterstaining (blue). The localization of IKZF1 was observed with a Leica microscope (original magnification ×200). See the article by Li et al.

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