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Issue Archive

Volume 9, Issue 22
November 25 2025
In Progress
Blood Advances Cover Image for Volume 9, Issue 22
In this Issue

Table of Contents

Severe parvovirus B19 infection in patients with sickle cell disease hospitalized in intensive care units
Ségolène Gendreau,Louis-Marie Coupry,Pierre Cappy,Alexandra Beurton,Nicolas Verger,Anoosha Habibi,Maïté Agbakou,Sylvain Le Jeune,Laurent Argaud,Serge Barmo,Gauthier Blonz,Pierre Cougoul,Stéphanie Houcke,Antoine Lafarge,Arnaud Ly,Andréa Pastissier,Armand Mekontso Dessap,Slim Fourati,Nicolas de Prost
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Supplemental data
Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression
Mark Perfetto,Aidan Danoff,Muhammad Ishfaq,Heidi Monroe,Aiden Mohideen,Meilin Chen,Jesus Tejero,Amber N. Stratman,Satoshi Okawa,Yvette Y. Yien
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Supplemental data
The immune receptor FcRγ-chain mediates CD36-induced platelet activation and thrombosis by oxidized low-density lipoproteins
Katie S. Wraith,Jawad S. Khalil,Ahmed A. Aburima,Lih T. Cheah,Matthew S. Hindle,Martin Berger,Romez Uddin,Hoor Ayub,Mary McKay,Rui-Gang Xu,Robert A. S. Ariëns,Mark T. Kearney,Michael G. Tomlinson,Khalid M. Naseem
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Supplemental data
FcR γ-chain and platelet hyperactivity
Roy L. Silverstein
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ASH sickle cell disease CPKD guidelines report
Robert I. Liem,Madeleine Verhovsek,Ted Wun,Sophie Lanzkron
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Addition of romiplostim to immunosuppressive therapy as first-line treatment for patients with aplastic anemia
Clinical Trials & Observations
Jong Wook Lee,Jun Ho Jang,Hirohito Yamazaki,Masashi Sawa,Masahiro Kizaki,Yoshiaki Tomiyama,Koji Nagafuji,Kensuke Usuki,Jyh-Pyng Gau,Yasuyoshi Morita,Jih-Luh Tang,Hung Chang,Masayoshi Noshiro,Akira Matsuda,Keiya Ozawa,Kinuko Mitani,Yoshinobu Kanda,Shinji Nakao
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Supplemental data
Characteristics and outcomes of Kaposi sarcoma herpesvirus–associated inflammatory cytokine syndrome
Clinical Trials & Observations
Ramya Ramaswami,Kathryn Lurain,Mark N. Polizzotto,Anaida Widell,Irene Ekwede,Elena Tassi,Adam Rupert,Vickie A. Marshall,Mark J. Roth,Armando C. Filie,Stefania Pittaluga,Elaine S. Jaffe,Hao-Wei Wang,Denise Whitby,Thomas S. Uldrick,Robert Yarchoan
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Supplemental data
Modification of belantamab mafodotin dosing to balance efficacy and tolerability in the DREAMM-7 and DREAMM-8 trials
Clinical Trials & Observations
María-Victoria Mateos,Suzanne Trudel,Hang Quach,Paweł Robak,Meral Beksac,Ludek Pour,Marek Hus,Kihyun Kim,Vera Zherebtsova,Sosana Delimpasi,Tomas Jelínek,Christopher Ward,P. Joy Ho,Vladimir Vorobyev,Marcelo Pitombeira de Lacerda,Gracia Aparecida-Martinez,Ivan Spicka,Jakub Radocha,Michele Cavo,Claudio Cerchione,Chengcheng Fu,Kazuhito Suzuki,Rachel Rogers,Amy Phillips-Jones,Zhaohui Wang,Hena Baig,Jodie Wilkes,Xiaoou L. Zhou,Eric Lewis,Lydia Eccersley,Neal Sule,Prani Paka,Joanna B. Opalinska,Pralay Mukhopadhyay,Vania Hungria,Meletios Athanasios Dimopoulos
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Supplemental data
Sustained survival benefit of emicizumab and postponed immunosuppression in acquired hemophilia A
Clinical Trials & Observations
Inga M. Schimansky,Christiane Dobbelstein,Robert Klamroth,Christina Hart,Ulrich J. Sachs,Richard Greil,Paul Knöbl,Johannes Oldenburg,Wolfgang Miesbach,Christian Pfrepper,Karolin Trautmann-Grill,Patrick Möhnle,Katharina Holstein,Hermann Eichler,Sonja Werwitzke,Andreas Tiede
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Supplemental data
Non-DLBCL monomorphic and Hodgkin lymphoma PTLD: clinical insights and treatment strategies
Suheil Albert Atallah-Yunes,Arushi Khurana,Thomas M. Habermann
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Priapism before and after hematopoietic stem cell therapy in individuals with sickle cell disease
Jose A. Mejias-Figueroa,Santosh L. Saraf,Clifford M. Takemoto,Mark Rodeghier,Michael R. DeBaun
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The MAGIC composite response: a novel end point integrating clinical and biomarker parameters for acute GVHD
Yu Akahoshi,Joseph Portelli,Nikolaos Katsivelos,Ioannis E. Louloudis,Paibel Aguayo-Hiraldo,Francis Ayuk,Chantiya Chanswangphuwana,Hannah K. Choe,Matthias Eder,Aaron M. Etra,Elizabeth O. Hexner,Carrie L. Kitko,Sabrina Kraus,Pietro Merli,Timothy S. Olson,Ivan Pasic,Muna Qayed,Ran Reshef,Tal Schechter,Julia Marx,Evelyn Ullrich,Ingrid Vasova,Daniela Weber,Matthias Wölfl,Robert Zeiser,Janna Baez,Gilbert Eng,Sigrun Gleich,Steven Kowalyk,George Morales,Nikolaos Spyrou,Rachel Young,Zachariah DeFilipp,William J. Hogan,Ryotaro Nakamura,John E. Levine,James L. M. Ferrara
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Supplemental data
Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children’s Oncology Group report
John A. Ligon,Lingyun Ji,Alice Dang,Xinxin Xu,Susan R. Rheingold,Deepa Bhojwani,Meenakshi Devidas,John A. Kairalla,Mary Shago,Nyla A. Heerema,Andrew J. Carroll,Michael Borowitz,Brent L. Wood,Naomi J. Winick,William L. Carroll,Stephen P. Hunger,Elizabeth A. Raetz,Mignon L. Loh,Sumit Gupta,Lena E. Winestone
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Supplemental data
RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids
Xiaolin Meng,Janine E. Melsen,Rosalie van der Holst,Bas de Mooij,Sandra Vloemans,Marja van Eggermond,Dagmar Berghuis,Arjan C. Lankester,Sander de Kivit,Karin Pike-Overzet,Anton W. Langerak,Frank J. T. Staal,Lisa M. Ott de Bruin,Kirsten Canté-Barrett
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Supplemental data
An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy
Emily J. Mason,Anna M. Crain,Michael E. Scheurer,Philip J. Lupo,Karen R. Rabin,Olga A. Taylor,Marley Roberts,John P. Woodhouse,Ashley Chavana,Kathleen Ludwig,Laura Klesse,Kenneth Heym,Timothy Griffin,Rodrigo Erana,Juan Carlos Bernini,M. Monica Gramatges,Joanna S. Yi,Sandi L. Pruitt,M. Brooke Bernhardt,Hong Zhu,Steven D. Mittelman,Van Huynh,Etan Orgel,Jeremy M. Schraw,Austin L. Brown
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Supplemental data
Prospective real-world evaluation of t(11;14) prevalence and disease biology in multiple myeloma: MEDICI study analysis
Clinical Trials & Observations
Andrew Spencer,Maria Gavriatopoulou,Daniel Coriu,Anna Lysén,Norma C. Gutiérrez,Fernando Escalante,Dorotea Beatriz Eugenia Fantl,Roman Hájek,Fernanda Seguro,Gurbakhash Kaur,Rosane Bittencourt,Sandra Basic Kinda,Michael P. Chu,Hana Safah,Joaquín Martinez-Lopez,Edvan de Queiroz Crusoé,Danielle Leão Cordeiro de Farias,Massimo Offidani,Elham Askari,Ömür Gökmen Sevindik,Vladimir Maisnar,Chieh-Lin Teng,Olivia Hughes,Rebekah Taylor,Kristin Lehn,Dai Feng,Raphaële Thiébaut-Millot,Xiaotong Li,Lauren Murray,Paul Jung,Emily L. Rossi,Sarah Kongpachith,Alex Nichol,Jeremy A. Ross,Carlos Hader
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Supplemental data
TLR2 agonism suppresses myeloid leukemogenesis by reprogramming leukemia stem cells
Michael E. Lawler,Jennifer S. Romer-Seibert,Michael S. Bowman,Ramkrishna Mitra,Christine M. Eischen,Robert L. Bowman,Sara E. Meyer
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Supplemental data
Diagnosis of von Willebrand disease
Mackenzie Bowman,Paula James
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Neighborhood socioeconomic status and overall survival among children with acute lymphoblastic leukemia
Clinical Trials & Observations
Anna L. Hoppmann,Deborah M. Hurley,Stuart Cramer,Monique J. Brown,Rahul Ghosal,Anthony J. Alberg,Smita Bhatia
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Supplemental data
Frail subgroups determine heterogeneous outcomes in older patients with NDMM: long-term follow-up of the HOVON 143 trial
Clinical Trials & Observations
Febe Smits,Kaz Groen,Mark-David Levin,Claudia A. M. Stege,Roel van Kampen,Ellen van der Spek,Inger Nijhof,Yavuz M. Bilgin,Noortje Thielen,Inge Ludwig,Esther G. M. de Waal,Yorick Sandberg,Alain Kentos,Gert-Jan Timmers,Josien C. Regelink,Matthijs Westerman,Koen de Heer,Marie-Christiane Vekemans,Nazik Durdu-Rayman,Nicole C. H. P. de Graauw,Maarten R. Seefat,Niels W. C. J. van de Donk,Paula F. Ypma,Kazem Nasserinejad,Sonja Zweegman,for the HOVON 143 Study Group
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Supplemental data
Infections and parameters of humoral immunity with talquetamab in relapsed/refractory multiple myeloma in MonumenTAL-1
Clinical Trials & Observations
Carolina Schinke,Paula Rodriguez-Otero,Niels W. C. J. van de Donk,Brea Lipe,Noa Lavi,Leo Rasche,Samir Parekh,Oliver Van Oekelen,Deeksha Vishwamitra,Sheri Skerget,Diana Cortes-Selva,Raluca Verona,Brandi Hilder,Tara Masterson,Michela Campagna,Sheetal Khedkar,Thomas Renaud,Jaszianne Tolbert,Colleen Kane,Kathleen S. Gray,Ibrahim Saber,Christoph Heuck,Ajai Chari
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Supplemental data
Bcl-xL inhibition potentiates interferon-induced apoptosis in MPN stem cells
Megan J. Bywater,Rohit Haldar,Yashaswini Janardhanan,Emily Cooper,Leanne Cooper,Siu Hang Natalie Chan,Noah Hayes,Victoria Ling,Jasmin Straube,Steven W. Lane
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Supplemental data
Beyond platelet counts: assessing safety of postsplenectomy TPO-RA use in ITP
Ruah Alyamany,Damon E. Houghton,Meera Sridharan,Rajiv K. Pruthi,Surbhi Shah,Richard C. Godby,Alexandra Wolanskyj-Spinner,Ronald S. Go
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Supplemental data
An AI model classifies risks of early relapse post–CAR T-cell therapy in a multicenter real-world population with DLBCL
Clinical Trials & Observations
Michelle Wang,Krishna V. Komanduri,Debajyoti Datta,Ayan Patel,Barbee Whitaker,Artur Belov,Benjamin Rubin,Rohit Vashist,Rosa Rodriguez-Monguio,Pelin Cinar,Steven Anderson,Atul J. Butte
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Supplemental data
Debunking myths: sickle cell trait, crises, and sudden death
Michael R. DeBaun,Corey J. Hebert,Yvette M. Miller
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Defining and treating KICS: experience from the largest cohort yet
Casey L. McAtee,Nader Kim El-Mallawany
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FcR γ-chain and platelet hyperactivity
Roy L. Silverstein
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Artificial intelligence–based flow cytometry for the diagnosis of B-cell chronic lymphoproliferative disorders
Laurent Mauvieux,Raoul Herbrecht,Alice Eischen,Anne-Cécile Galoisy,Delphine Rolland,Carine Gervais,Caroline Mayeur-Rousse,Sarah Hueber-Bonnot,Alina Nicolae,Luc-Matthieu Fornecker,Thibaut Goetsch,François Severac,Razvan Bizoï,Thibaut Fabacher,Laurent Miguet
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Supplemental data
Deferral of immunosuppression in acquired hemophilia
Clinical Trials & Observations
Jerome Teitel,Jean St-Louis
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  • Cover Image

    Cover Image

    issue cover

    Imaging of Tg (lcr:eGFP) zebrafish embryo at 4 days post fertilization (dpf), where globin-expressing erythroid cells express green fluorescent protein (GFP) (green). The boxed region is the caudal hematopoietic tissue (CHT), from which definitive erythroid cells emerge at this developmental stage. See the article by Perfetto et al.

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Defining and treating KICS: experience from the largest cohort yet
FcR γ-chain and platelet hyperactivity
Deferral of immunosuppression in acquired hemophilia
Reproducibility and repeatability of the Myoton to quantify sclerotic chronic graft-versus-host disease
Artificial intelligence–based flow cytometry for the diagnosis of B-cell chronic lymphoproliferative disorders

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