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Journal Articles

Canonical Wnt: a safeguard and threat for erythropoiesis

Rosa A. Krimpenfort, Micha Nethe
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3726–3735.
https://doi.org/10.1182/bloodadvances.2021004845
Published: 2021
Journal Articles

Germline variants in DNA repair genes, including BRCA1 / 2 , may cause familial myeloproliferative neoplasms

Clinical Trials & Observations
Miriam Elbracht, Robert Meyer, Kim Kricheldorf, Deniz Gezer, Eggermann Thomas, Beate Betz, Ingo Kurth, Lino L. Teichmann, Tim H. Brümmendorf, Ulrich Germing, Susanne Isfort, Steffen Koschmieder
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3373–3376.
https://doi.org/10.1182/bloodadvances.2021004811
Published: 2021
Journal Articles

Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia

Clinical Trials & Observations
Sebastian Stasik, Jan-Niklas Eckardt, Michael Kramer, Christoph Röllig, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Volker Kunzmann, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan Krause, Regina Herbst, Mathias Hänel, Norbert Frickhofen, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Zdenek Rácil, Uwe Platzbecker, Wolfgang E. Berdel, Jiri Mayer, Hubert Serve, Carsten Müller-Tidow, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Jan M. Middeke, Christian Thiede, on behalf of the Study Alliance Leukemia (SAL)
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3279–3289.
https://doi.org/10.1182/bloodadvances.2021004631
Published: 2021
Includes: Supplemental data
Journal Articles

Splicing factor gene mutations in acute myeloid leukemia offer additive value if incorporated in current risk classification

Clinical Trials & Observations
Inge van der Werf, Anna Wojtuszkiewicz, Manja Meggendorfer, Stephan Hutter, Constance Baer, Martijn Heymans, Peter J. M. Valk, Wolfgang Kern, Claudia Haferlach, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Jacqueline Cloos, Torsten Haferlach
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3254–3265.
https://doi.org/10.1182/bloodadvances.2021004556
Published: 2021
Includes: Supplemental data
Journal Articles

Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications

Clinical Trials & Observations
Marta Lopes, Tiago L. Duarte, Maria J. Teles, Laura Mosteo, Sérgio Chacim, Eliana Aguiar, Joana Pereira-Reis, Mónica Oliveira, André M. N. Silva, Nuno Gonçalves, Gabriela Martins, Isabella Y. Kong, Magnus Zethoven, Stephin Vervoort, Sandra Martins, Miguel Quintela, Edwin D Hawkins, Fernanda Trigo, João T. Guimarães, José M. Mariz, Graça Porto, Delfim Duarte
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3102–3112.
https://doi.org/10.1182/bloodadvances.2021004373
Published: 2021
Includes: Supplemental data
Journal Articles

Phase 3 randomized trial of chemotherapy with or without oblimersen in older AML patients: CALGB 10201 (Alliance)

Clinical Trials & Observations
Alison R. Walker, Guido Marcucci, Jun Yin, William Blum, Wendy Stock, Jessica Kohlschmidt, Krzysztof Mrózek, Andrew J. Carroll, Ann-Kathrin Eisfeld, Eunice S. Wang, Sawyer Jacobson, Jonathan E. Kolitz, Mohan Thakuri, Grerk Sutamtewagul, Ravi Vij, Robert K. Stuart, John C. Byrd, Clara D. Bloomfield, Richard M. Stone, Richard A. Larson
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2775–2787.
https://doi.org/10.1182/bloodadvances.2021004233
Published: 2021
Includes: Supplemental data
Journal Articles

Zhou Z, Nath R, Cerny J, et al. Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a CIBMTR report. Blood Adv . 2020;4(13):3180-3190.

Journal: Blood Advances
Blood Adv (2021) 5 (13): 2752.
https://doi.org/10.1182/bloodadvances.2021005193
Published: 2021
Journal Articles

Mesothelin is a novel cell surface disease marker and potential therapeutic target in acute myeloid leukemia

Allison J. Kaeding, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Rhonda E. Ries, Todd A. Alonzo, Robert B. Gerbing, Colin Correnti, Michael R. Loken, Lisa Eidenschink Broderson, Laura Pardo, Quy H. Le, Thao Tang, Amanda R. Leonti, Jenny L. Smith, Cassie K. Chou, Min Xu, Tim Triche, Jr, Steven M. Kornblau, E. Anders Kolb, Katherine Tarlock, Soheil Meshinchi
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2350–2361.
https://doi.org/10.1182/bloodadvances.2021004424
Published: 2021
Includes: Supplemental data
Journal Articles

Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations

Clinical Trials & Observations
Michael Heuser, Bennet Heida, Konstantin Büttner, Clara Philine Wienecke, Katrin Teich, Carolin Funke, Maximilian Brandes, Piroska Klement, Alessandro Liebich, Martin Wichmann, Blerina Neziri, Anuhar Chaturvedi, Arnold Kloos, Konstantinos Mintzas, Verena I. Gaidzik, Peter Paschka, Lars Bullinger, Walter Fiedler, Albert Heim, Wolfram Puppe, Jürgen Krauter, Konstanze Döhner, Hartmut Döhner, Arnold Ganser, Michael Stadler, Lothar Hambach, Razif Gabdoulline, Felicitas Thol
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2294–2304.
https://doi.org/10.1182/bloodadvances.2021004367
Published: 2021
Includes: Supplemental data
Journal Articles

LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα

Kensaku Kohrogi, Shinjiro Hino, Akihisa Sakamoto, Kotaro Anan, Ryuta Takase, Hirotaka Araki, Yuko Hino, Kazutaka Araki, Tetsuya Sato, Kimitoshi Nakamura, Mitsuyoshi Nakao
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2305–2318.
https://doi.org/10.1182/bloodadvances.2020003521
Published: 2021
Includes: Supplemental data
Journal Articles

Single-center experience with venetoclax combinations in patients with newly diagnosed and relapsed AML evolving from MPNs

Clinical Trials & Observations
Lucia Masarova, Courtney D. DiNardo, Prithviraj Bose, Naveen Pemmaraju, Naval G. Daver, Tapan M. Kadia, Helen T. Chifotides, Lingsha Zhou, Gautam Borthakur, Zeev Estrov, Marina Konopleva, Srdan Verstovsek
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2156–2164.
https://doi.org/10.1182/bloodadvances.2020003934
Published: 2021
Includes: Supplemental data
Journal Articles

Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax

Clinical Trials & Observations
Curtis A. Lachowiez, Sanam Loghavi, Ken Furudate, Guillermo Montalban-Bravo, Abhishek Maiti, Tapan Kadia, Naval Daver, Gautam Borthakur, Naveen Pemmaraju, Koji Sasaki, Yesid Alvarado, Musa Yilmaz, Nicholas J. Short, Kelly Chien, Maro Ohanian, Sherry Pierce, Keyur P. Patel, Elias Jabbour, Farhad Ravandi, Hagop M. Kantarjian, Guillermo Garcia-Manero, Koichi Takahashi, Marina Y. Konopleva, Courtney D. DiNardo
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2173–2183.
https://doi.org/10.1182/bloodadvances.2020004173
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia

Clinical Trials & Observations
Abhishek Maiti, Courtney D. DiNardo, Sa A. Wang, Jeffrey Jorgensen, Tapan M. Kadia, Naval G. Daver, Nicholas J. Short, Musa Yilmaz, Naveen Pemmaraju, Gautam Borthakur, Prithviraj Bose, Ghayas C. Issa, Alessandra Ferrajoli, Elias J. Jabbour, Nitin Jain, Guillermo Garcia-Manero, Maro Ohanian, Koichi Takahashi, Guillermo Montalban-Bravo, Lucia Masarova, Jan A. Burger, Philip A. Thompson, Srdan Verstovsek, Koji Sasaki, Michael Andreeff, Caitlin R. Rausch, Kathryn S. Montalbano, Sherry Pierce, Wei Qiao, Jing Ning, Hagop M. Kantarjian, Marina Y. Konopleva, Farhad Ravandi
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1876–1883.
https://doi.org/10.1182/bloodadvances.2020003717
Published: 2021
Includes: Supplemental data
Journal Articles

Minimally myelosuppressive regimen for remission induction in pediatric AML: long-term results of an observational study

Clinical Trials & Observations
Yixin Hu, Aili Chen, Li Gao, Hailong He, Shuting Jiang, Xinchang Zheng, Peifang Xiao, Jun Lu, Yi Wang, Jie Li, Jianqin Li, Junjie Fan, Yanhua Yao, Jing Ling, Liyan Fan, Shengqin Cheng, Cheng Cheng, Fang Fang, Jian Pan, Qian-fei Wang, Raul C. Ribeiro, Shaoyan Hu
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1837–1847.
https://doi.org/10.1182/bloodadvances.2020003453
Published: 2021
Includes: Supplemental data
Journal Articles

Gene expression signature predicts relapse in adult patients with cytogenetically normal acute myeloid leukemia

Clinical Trials & Observations
Christopher J. Walker, Krzysztof Mrózek, Hatice Gulcin Ozer, Deedra Nicolet, Jessica Kohlschmidt, Dimitrios Papaioannou, Luke K. Genutis, Marius Bill, Bayard L. Powell, Geoffrey L. Uy, Jonathan E. Kolitz, Andrew J. Carroll, Richard M. Stone, Ramiro Garzon, John C. Byrd, Ann-Kathrin Eisfeld, Albert de la Chapelle, Clara D. Bloomfield
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1474–1482.
https://doi.org/10.1182/bloodadvances.2020003727
Published: 2021
Includes: Supplemental data
Journal Articles

Deregulated expression of circular RNAs in acute myeloid leukemia

Susanne Lux, Tamara J. Blätte, Bernhard Gillissen, Antje Richter, Sibylle Cocciardi, Sabrina Skambraks, Klaus Schwarz, Hubert Schrezenmeier, Hartmut Döhner, Konstanze Döhner, Anna Dolnik, Lars Bullinger
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1490–1503.
https://doi.org/10.1182/bloodadvances.2020003230
Published: 2021
Includes: Supplemental data
Journal Articles

Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia

Clinical Trials & Observations
Antonio Pierini, Loredana Ruggeri, Alessandra Carotti, Franca Falzetti, Simonetta Saldi, Adelmo Terenzi, Claudio Zucchetti, Gianluca Ingrosso, Tiziana Zei, Roberta Iacucci Ostini, Sara Piccinelli, Samanta Bonato, Sara Tricarico, Antonella Mancusi, Sara Ciardelli, Roberto Limongello, Mara Merluzzi, Mauro Di Ianni, Rita Tognellini, Olivia Minelli, Cristina Mecucci, Maria Paola Martelli, Brunangelo Falini, Massimo Fabrizio Martelli, Cynthia Aristei, Andrea Velardi
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1199–1208.
https://doi.org/10.1182/bloodadvances.2020003739
Published: 2021
Includes: Supplemental data
Journal Articles

Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML

Sylvain Mareschal, Anna Palau, Johan Lindberg, Philippe Ruminy, Christer Nilsson, Sofia Bengtzén, Marie Engvall, Anna Eriksson, Anne Neddermeyer, Vinciane Marchand, Monika Jansson, My Björklund, Fabrice Jardin, Mattias Rantalainen, Andreas Lennartsson, Lucia Cavelier, Henrik Grönberg, Sören Lehmann
Journal: Blood Advances
Blood Adv (2021) 5 (4): 1003–1016.
https://doi.org/10.1182/bloodadvances.2020002517
Published: 2021
Includes: Supplemental data
Journal Articles

Cost-effectiveness of azacitidine and venetoclax in unfit patients with previously untreated acute myeloid leukemia

Kishan K. Patel, Amer M. Zeidan, Rory M. Shallis, Thomas Prebet, Nikolai Podoltsev, Scott F. Huntington
Journal: Blood Advances
Blood Adv (2021) 5 (4): 994–1002.
https://doi.org/10.1182/bloodadvances.2020003902
Published: 2021
Includes: Supplemental data
Journal Articles

Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

Svea Stratmann, Sara A. Yones, Markus Mayrhofer, Nina Norgren, Aron Skaftason, Jitong Sun, Karolina Smolinska, Jan Komorowski, Morten Krogh Herlin, Christer Sundström, Anna Eriksson, Martin Höglund, Josefine Palle, Jonas Abrahamsson, Kirsi Jahnukainen, Monica Cheng Munthe-Kaas, Bernward Zeller, Katja Pokrovskaja Tamm, Lucia Cavelier, Linda Holmfeldt
Journal: Blood Advances
Blood Adv (2021) 5 (3): 900–912.
https://doi.org/10.1182/bloodadvances.2020003709
Published: 2021
Includes: Supplemental data